scholarly journals INTAKE OF ULTRAPROCESSED FOODS IS ASSOCIATED WITH INFLAMMATORY MARKERS IN BRAZILIAN ADOLESCENTS

2021 ◽  
pp. 1-26
Author(s):  
Glauciane Márcia dos Santos Martins ◽  
Ana Karina Teixeira da Cunha França ◽  
Poliana Cristina de Almeida Fonseca Viola ◽  
Carolina Abreu de Carvalho ◽  
Karla Danielle Silva Marques ◽  
...  
Keyword(s):  
Energy Consumption ◽  
Inflammatory Markers ◽  
Saturated Fat ◽  
Population Based ◽  
Poor Quality ◽  
Northeastern Brazil ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Lower Protein ◽  
Simple Carbohydrates

ABSTRACT Objective: To evaluate the association of the consumption of foods of the ultra-processed group (UPF) with inflammatory markers in the adolescent population in Northeastern Brazil. Design: A cross-sectional population-based study. Food consumption was evaluated using two 24-hour dietary recalls using the NOVA classification for food processing levels. The following inflammatory markers were evaluated: adiponectin, interleukin-6 (IL-6), interleukin-8 (IL-8), C-reactive protein (CRP), and tumor necrosis factor (TNF-α). Multivariate linear regression was used to investigate the association between the percentage of UPF energy contribution and inflammatory markers. Setting: São Luís, Maranhão, Brazil. Participants: The sample consisted of 391 male and female adolescents, aged from 17 to 18 years. Results: The average daily energy consumption by adolescents was 8032.9 kJ/day, of which 26.1% originated from UPF. The upper tertile (T3) of UPF consumption presented higher intake of simple carbohydrates, lipids, saturated fat, and sodium and lower protein intake. Individuals in T3 presented higher serum leptin and CRP levels (p <0.05). Adolescents with UPF energy consumption ≥30.0% (Tertile 3 of UPF) had a 79% [exp(0.58)=1.79] increase in IL-8 levels when compared to adolescents in Tertile 1 of UPF (p = 0.013). Conclusions: The association between the consumption of UPF, poor quality diet, and pro-inflammatory markers have important harmful effects that can be observed as early as in adolescence.

scholarly journals Associations between dietary inflammatory index and inflammatory markers in the Asklepios Study

2015 ◽  
Vol 113 (4) ◽  
pp. 665-671 ◽  
Author(s):  
Nitin Shivappa ◽  
James R. Hébert ◽  
Ernst R. Rietzschel ◽  
Marc L. De Buyzere ◽  
Michel Langlois ◽  
...  
Keyword(s):  
Inflammatory Markers ◽  
Smoking Status ◽  
Population Based ◽  
Cross Sectional Study ◽  
Lipid Lowering ◽  
Dietary Inflammatory Index ◽  
Cross Sectional ◽  
Inflammatory Index ◽  
Reactive Protein ◽  
Dietary Index

Previous research has shown that nutrients and certain food items influence inflammation. However, little is known about the associations between diet, as a whole, and inflammatory markers. In the present study, we examined the ability of a FFQ-derived dietary inflammatory index (DII) to predict inflammation. Data from a Belgian cross-sectional study of 2524 generally healthy subjects (age 35–55 years) were used. The DII is a population-based, literature-derived dietary index that was developed to predict inflammation and inflammation-related chronic diseases. The DII was calculated from FFQ-derived dietary information and tested against inflammatory markers, namely C-reactive protein (CRP), IL-6, homocysteine and fibrinogen. Analyses were performed using multivariable logistic regression, adjusting for energy, age, sex, BMI, smoking status, education level, use of non-steroidal anti-inflammatory drugs, blood pressure, use of oral contraceptives, anti-hypertensive therapy, lipid-lowering drugs and physical activity. Multivariable analyses showed significant positive associations between the DII and the inflammatory markers IL-6 (>1·6 pg/ml) (OR 1·19, 95 % CI 1·04, 1·36) and homocysteine (>15 μmol/l) (OR 1·56, 95 % CI 1·25, 1·94). No significant associations were observed between the DII and the inflammatory markers CRP and fibrinogen. These results reinforce the fact that diet, as a whole, plays an important role in modifying inflammation.

scholarly journals Analysis of inflammatory markers in patients with abnormal circadian rhythm of blood pressure

2021 ◽  
Author(s):  
Néstor Agra ◽  
Ana Teresa Afonso ◽  
Antón Sande ◽  
Ignacio Veleiro ◽  
José Enrique Paz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Circadian Rhythm ◽  
Inflammatory Markers ◽  
Antihypertensive Drugs ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Inflammatory Status ◽  
Retrospective Data Analysis ◽  
Cross Sectional Design

IntroductionInflammatory status could play a role in alterations of blood pressure (BP) circadian rhythm. The aim of our study is to compare levels of usual inflammatory markers in patients with and without circadian BP abnormalities.Material and methodsThis is a cross-sectional design study with retrospective data analysis which included patients from an Internal Medicine Department with normal and high BP levels older than 18 years who were separated into two groups according to the circadian profile of BP (dipper and non-dipper) based on the results of 24-hour ambulatory BP monitoring. Patients were assessed for demographic characteristics and cardiovascular risk factors. We considered as inflammatory markers the platelet count (PTC), erythrocyte sedimentation rate (ESR), ultra-sensitive C-reactive protein, ferritin, fibrinogen, and uric acid.ResultsThe study included 551 patients (mean age of 54 years, 47% women). The non-dipper group had a higher percentage of individuals with higher ESR (OR = 1.77, 95% CI: 1.23–1.55, p = 0.001), uric acid (OR = 1.50, 95% CI: 1.04–2.16, p = 0.028) and fibrinogen (OR = 1.72, 95% CI: 1.18–2.51, p = 0.001) and a higher percentage of patients with higher PTC (OR = 0.54, 95% CI: 0.37–0.78, p = 0.005). These results were independent of age, waist circumference, presence of arterial hypertension, diabetes or hyperlipidemia, and use of antihypertensive drugs including renin angiotensin aldosterone system blockers.ConclusionsPatients with impaired circadian BP rhythm were associated with an unfavorable inflammatory status independently of BP levels. This fact could play a role in the prognostic differences observed between dipper and non-dipper patients.

scholarly journals The impact of C-reactive protein levels on headache frequency in the HUNT study 2006–2008

BMC Neurology ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Knut Hagen ◽  
Lars Jacob Stovner ◽  
Kristian Bernhard Nilsen ◽  
Espen Saxhaug Kristoffersen ◽  
Bendik Slagsvold Winsvold
Keyword(s):  
Migraine With Aura ◽  
Large Scale ◽  
Population Based ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Population Based Study ◽  
Reactive Protein ◽  
Scale Population ◽  
Hs Crp ◽  
The Impact

Abstract Background Increased high sensitivity C- reactive protein (hs-CRP) levels have been found in many earlier studies on migraine, and recently also in persons with migraine and insomnia. The aim of this study was to see whether these findings could be reproduced in a large-scale population-based study. Methods A total of 50,807 (54%) out of 94,194 invited aged ≥20 years or older participated in the third wave of the Nord-Trøndelag Health Study study performed in 2006–2008. Among these, 38,807 (41%) had valid measures of hs-CRP and answered questions on headache and insomnia. Elevated hs-CRP was defined as > 3.0 mg/L. The cross-sectional association with headache was estimated by multivariate analyses using multiple logistic regression. The precision of the odds ratio (OR) was assessed with 95% confidence interval (CI). Results In the fully adjusted model, elevated hs-CRP was associated with migraine (OR 1.14, 95% CI 1.04–1.25) and migraine with aura (OR 1.15, 95% CI 1.03–1.29). The association was strongest among individuals with headache ≥15 days/month for any headache (OR 1.26, 95% CI 1.08–1.48), migraine (OR 1.62, 95% CI 1.21–2.17), and migraine with aura (OR 1.84, 95% CI 1.27–2.67). No clear relationship was found between elevated hs-CRP and headache less than 7 days/month or with insomnia. Conclusions Cross-sectional data from this large-scale population-based study showed that elevated hs-CRP was associated with headache ≥7 days/month, especially evident for migraine with aura.

scholarly journals Association between childhood infection, serum inflammatory markers and intelligence: findings from a population-based prospective birth cohort study

2017 ◽  
Vol 146 (2) ◽  
pp. 256-264 ◽  
Author(s):  
N. MACKINNON ◽  
S. ZAMMIT ◽  
G. LEWIS ◽  
P. B. JONES ◽  
G. M. KHANDAKER
Keyword(s):  
Birth Cohort ◽  
Inflammatory Markers ◽  
Intellectual Development ◽  
Inflammatory Marker ◽  
Population Based ◽  
Birth Cohort Study ◽  
Reactive Protein ◽  
Parents And Children ◽  
High Infection ◽  
Prospective Birth Cohort

SUMMARYA link between infection, inflammation, neurodevelopment and adult illnesses has been proposed. The objective of this study was to examine the association between infection burden during childhood – a critical period of development for the immune and nervous systems – and subsequent systemic inflammatory markers and general intelligence. In the Avon Longitudinal Study of Parents and Children, a prospective birth cohort in England, we examined the association of exposure to infections during childhood, assessed at seven follow-ups between age 1·5 and 7·5 years, with subsequent: (1) serum interleukin 6 and C-reactive protein (CRP) levels at age 9; (2) intelligence quotient (IQ) at age 8. We also examined the relationship between inflammatory markers and IQ. Very high infection burden (90+ percentile) was associated with higher CRP levels, but this relationship was explained by body mass index (adjusted odds ratio (OR) 1·19; 95% confidence interval (CI) 0·95–1·50), maternal occupation (adjusted OR 1·23; 95% CI 0·98–1·55) and atopic disorders (adjusted OR 1·24; 95% CI 0·98–1·55). Higher CRP levels were associated with lower IQ; adjusted β = −0·79 (95% CI −1·31 to −0·27); P = 0·003. There was no strong evidence for an association between infection and IQ. The findings indicate that childhood infections do not have an independent, lasting effect on circulating inflammatory marker levels subsequently in childhood; however, elevated inflammatory markers may be harmful for intellectual development/function.

scholarly journals How well do Australian women comply with dietary guidelines?

2004 ◽  
Vol 7 (3) ◽  
pp. 443-452 ◽  
Author(s):  
Kylie Ball ◽  
Gita D Mishra ◽  
Christopher W Thane ◽  
Allison Hodge
Keyword(s):  
Economic Status ◽  
Saturated Fat ◽  
Population Based ◽  
Dietary Guidelines ◽  
Dietary Recommendations ◽  
Middle Aged ◽  
National Guidelines ◽  
Cross Sectional ◽  
Behavioural Characteristics ◽  
Increased Risk

AbstractObjective:To investigate the proportion of middle-aged Australian women meeting national dietary recommendations and its variation according to selected sociodemographic and behavioural characteristics.Design:This cross-sectional population-based study used a food-frequency questionnaire to investigate dietary patterns and compliance with 13 commonly promoted dietary guidelines among a cohort of middle-aged women participating in the Australian Longitudinal Study on Women's Health.Setting:Nation-wide community-based survey.Subjects:A total of 10 561 women aged 50–55 years at the time of the survey in 2001.Results:Only about one-third of women complied with more than half of the guidelines, and only two women in the entire sample met all 13 guidelines examined. While guidelines for meat/fish/poultry/eggs/nuts/legumes and ‘extra’ foods (e.g. ice cream, chocolate, cakes, potatoes, pizza, hamburgers and wine) were met well, large percentages of women (68–88%) did not meet guidelines relating to the consumption of breads, cereal-based foods and dairy products, and intakes of total and saturated fat and iron. Women working in lower socio-economic status occupations, and women living alone or with people other than a partner and/or children, were at significantly increased risk of not meeting guidelines.Conclusions:The present results indicate that a large proportion of middle-aged Australian women are not meeting dietary guidelines. Without substantial changes in their diets, and help in making these changes, current national guidelines appear unachievable for many women.

scholarly journals Healthy Eating Index: Assessment of the Diet Quality of a Brazilian Elderly Population

2018 ◽  
Vol 11 ◽  
pp. 117863881881884
Author(s):  
Dalila Pinto de Souza Fernandes ◽  
Maria Sônia Lopes Duarte ◽  
Milene Cristine Pessoa ◽  
Sylvia do Carmo Castro Franceschini ◽  
Andréia Queiroz Ribeiro
Keyword(s):  
Healthy Eating ◽  
Diet Quality ◽  
Saturated Fat ◽  
Population Based ◽  
Cross Sectional Study ◽  
Whole Grains ◽  
Healthy Eating Index ◽  
Cross Sectional ◽  
Global Quality

Background: The food consumption assessment is necessary to monitor elderly’s nutritional status because it allows detecting nutrition deficits and guiding the elaboration of effective conducts. Objective: The objective of this study is to assess the global quality of the elderly’s diet in Viçosa—MG, Brazil. Methods: This is a population-based cross-sectional study, involving noninstitutionalized elderly. Diet quality was assessed through the Brazilian Healthy Eating Index-Revised (BHEI-R) validated to the Brazilian population. Results: The study comprised 620 elderly individuals. The mean total BHEI-R score was 64.28. The worse consumption scores concerned the components Whole grains, Milk and derivatives, Sodium, Total fruit, and Whole fruit. Approximately 82% scored zero (0%) for Whole grains and 67% for Sodium. Men presented significantly lower scores than women, who have presented maximal score in the same items. Women’s scores were not only significantly higher for Total fruit, Whole fruit, Milk and derivatives, but also significantly lower for Saturated fat. Discussion: Most elderly need to improve their diet quality. Strategies heading toward the improvement of diet quality must be priority in policies to health promotion toward the healthy and active aging.

scholarly journals The prevalence of rheumatoid arthritis in middle-aged and elderly people living in Naqu City, Tibet, Autonomous Region of China

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Qingxi Zhang ◽  
Qiang Liu ◽  
Chutong Lin ◽  
Yangjin Baima ◽  
Hu Li ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Population Based ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Autonomous Region ◽  
Reactive Protein ◽  
American College Of Rheumatology ◽  
European League Against Rheumatism ◽  
Tibet Autonomous Region ◽  
The Tibet Autonomous Region

Abstract Objective To estimate the prevalence of rheumatoid arthritis (RA) in the Tibet Autonomous Region (China). Methods A population-based cross-sectional survey was conducted on 1458 residents of Luoma Town, Tibet Autonomous Region, who were aged ≥ 40 years old. We interviewed participants using questionnaires, and rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA), and C-reactive protein (CRP) were determined. The identification of RA in this study was on the basis of criteria issued by the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) guideline. Results Herein, 782 participants completed all items of RA. The overall prevalence of RA was 4.86%, and the prevalence was higher in women than that in men (7.14% vs. 2.56%, p = 0.005). The age-standardized prevalence of RA was 6.30% (95% confidence interval (CI) 4.20–8.64%), which was 2.46% (95% CI 1.04%, 4.10%) and 9.59% (95% CI 5.93%, 13.77%) in men and women, respectively. Conclusion The prevalence of RA is relatively higher in the Tibet than that in other areas of China.

The prevalence of rheumatoid arthritis in middle-aged and elderly people in Tibet Autonomous Region of China

2020 ◽  
Author(s):  
Jianhao Lin ◽  
Qing Xi Zhang ◽  
Qiang Liu ◽  
Chu Tong Lin ◽  
Yangjin Baima ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Epidemiological Survey ◽  
Population Based ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Autonomous Region ◽  
Face To Face ◽  
Reactive Protein ◽  
Tibet Autonomous Region ◽  
Definition Of

Abstract Objective There has been no epidemiological survey of it in Tibet. We estimated the prevalence of rheumatoid arthritis in Luoma Town, Naqu City, Tibet Autonomous Region of China. Methods A population-based cross-sectional survey was conducted among 1458 residents of Luoma Town, Tibet Autonomous Region, aged ≥ 40 years. We used questionnaires in face-to-face interviews, anthropometric measurements and rheumatoid factor (RF), autoantibodies binding to citrullinated antigens (ACPA) and C-reactive protein (CRP) test. The definition of rheumatoid arthritis in this study was on the basis of new 2010 ACR/EULAR classification criteria. Results 782 participants completed all items of rheumatoid arthritis. The overall crude prevalence of rheumatoid arthritis was 4.86%. The prevalence was higher in women than in men (7.14% vs. 2.56%, P = 0.005). Tibetan had a higher age-standardized prevalence of rheumatoid arthritis 6.30% (95% confidence interval: 4.20% − 8.64%) compared with the other areas in China (range: 0.20% − 0.93%). Conclusion The prevalence of rheumatoid arthritis is relatively higher than other places in China.

scholarly journals Prevalence of Maternal Morbidity and Its Association with Socioeconomic Factors: A Population-based Survey of a City in Northeastern Brazil

2017 ◽  
Vol 39 (11) ◽  
pp. 587-595 ◽  
Author(s):  
Tatyana Rosendo ◽  
Angelo Roncalli ◽  
George Azevedo
Keyword(s):  
Socioeconomic Status ◽  
Prenatal Care ◽  
Maternal Morbidity ◽  
Associated Factors ◽  
Public Services ◽  
Population Based ◽  
Northeastern Brazil ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
Validated Questionnaire

Purpose To identify the prevalence of maternal morbidity and its socioeconomic, demographic and health care associated factors in a city in Northeastern Brazil. Methods A cross-sectional and population-based study was conducted, with a design based on multi-stage complex sampling. A validated questionnaire was applied to 848 women aged between 15 and 49 years identified in 8,227 households from 60 census tracts of Natal, the capital of the state of Rio Grande do Norte (RN), Brazil. The main outcome measure was maternal morbidity. The Poisson regression analysis, with 5% significance, was used for the analysis of the associated factors. Results The prevalence of maternal morbidity was of 21.2%. A bivariate analysis showed the following variables associated with an increased number of obstetric complications: non-white race (prevalence ratio [PR] =1.23; 95% confidence interval [95%CI]: 1.04–1.46); lower socioeconomic status (PR = 1.33; 95%CI: 1.12–1.58); prenatal care performed in public services (PR = 1.42; 95%CI: 1.16–1.72): women that were not advised during prenatal care about where they should deliver (PR = 1.24; 95%CI: 1.05–1.46); delivery in public services (PR = 1.63; 95%CI: 1.30–2.03); need to search for more than one hospital for delivery (PR = 1.22; 95%CI: 1.03–1.45); and no companion at all times of delivery care (PR = 1.25, 95%CI: 1.05–1.48). The place where the delivery occurred (public or private) and the socioeconomic status remained significant in the final model. Conclusion Women in a worse socioeconomic situation and whose delivery was performed in public services had a higher prevalence of maternal morbidity. Such an association reinforces the need to strengthen public policies to tackle health inequalities through actions focusing on these determinants.

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