Issues arising from genetic change: Ruminants

2000 ◽  
Vol 27 ◽  
pp. 53-62 ◽  
Author(s):  
Seerp Tamminga
Keyword(s):  
High Risk ◽  
Dairy Cows ◽  
Evaluation System ◽  
Nutrient Supply ◽  
Negative Energy ◽  
Energy Requirements ◽  
Calving Interval ◽  
Reproductive Disorders ◽  
Predisposing Factor ◽  
Energy Density Distribution

AbstractIn nutritional terms productivity in dairy cows is best expressed in multiples of their energy requirements for maintenance, which is directly related to Metabolic Body Weight (MBW). Energy requirements can further be specified as those for free energy (fME), ketogenic energy (kME), glucogenic energy (gME) and aminogenic energy (aME). For maintenance, energy is required in an approximate ratio fME:gME:aME of 85:5:10.For a production level of 6x maintenance the required ratio of fME:kME:gME:aME is approximately 18:31:29:22, hence 70% of the required ME has to be delivered as specific nutrients.During their productive life, dairy cattle alternate periods with high and periods with low risk of an inadequate nutrient supply. A period of high risk is between 10 days pre-partum and 90 days postpartum. High risk in this period means a high susceptibility for metabolic and reproductive disorders, many of which are interrelated. Negative Energy Balance (NEB) in early lactation is a metabolic status that is almost inevitable in high yielding dairy cows. In severe cases this is an important predisposing factor for metabolic disorders (paturient paresis, fatty liver, ketosis, displaced abomasum) and reproductive disorders (undetected heat, delayed ovarian cycle, reduced fertility, increased between calving interval).Adequate nutrient supply is required from 2 weeks pre-partum onwards. Critical issues are energy density, distribution between structural and non-structural carbohydrates and distribution between fME, kME, gME and aME. Practical solutions, which can help alleviate the metabolic and reproductive problems, could be a nutrient based feed evaluation system, a lower peak yield combined with an improved persistence and maybe a deliberately increased calving interval.

scholarly journals Immunosuppression - postpartum diseases of dairy cows

2013 ◽  
Vol 29 (2) ◽  
pp. 211-222 ◽  
Author(s):  
M. Joksimovic-Todorovic ◽  
V. Davidovic
Keyword(s):  
Dairy Cows ◽  
Ketone Bodies ◽  
Animal Health ◽  
Great Influence ◽  
Negative Energy ◽  
Reproductive Disorders ◽  
Periparturient Period ◽  
Tissue Lipids ◽  
Tissue Damages ◽  
Immunosuppressive Action

Periparturient period in dairy cows is accompanied by numerous physiological, metabolic and nutritive changes. The way in which they occur and develop have a great influence on lactation performances, subclinical and clinical postparturient diseases and reproductive disorders, thus affecting the profitability as well. During periparturient period dairy cows may subject to the immune system function disorders. This immunosuppression leads to increased number of severe cases of infections (mastitis, metritis, retained placenta and other health disorders). The cause of periparturient immunosuppression is unknown, although it is a subject of numerous studies which suggest that immune disfunction may be provoked by both metabolic and endocrine factors. Numerous authors suggest that negative energy balance, non-esterified fatty acids (NEFA), ketone bodies and hypocalcaemia play a significant role in the development of immunosuppression. It is well known that glucocorticoids exert an immunosuppressive action. The changes in the levels of estradiol and progesterone may have either a direct or indirect influence on immune defence. However, their effect on the development of this immunofunction is not long, since the changes in their concentrations are short-lasting. Some nutrients are involved in the function of immune cells thus minimizing the inflammatory damages, due to more efficient immune response. Numerous tissue damages during the infection are possible, as a consequence of oxidative stress - reaction of unstable oxidised molecules with tissue lipids, proteins and DNA. A great number of antioxidants are important for animal health, however, optimal concentrations and forms of these supplements for maximizing the immune function and tissue protection are still unknown.

scholarly journals Reproductive disorders in dairy cows of the southwest of Paraná

2018 ◽  
Vol 9 (3) ◽  
pp. 535-539
Author(s):  
Fernanda Elisa Giacomelli ◽  
ADALGIZA PINTO NETO ◽  
MARCELO FALCI MOTA ◽  
ANTÔNIO CAMPANHA MARTINEZ ◽  
LUIZ SÉRGIO MERLINI
Keyword(s):  
Dairy Cows ◽  
Milk Production ◽  
Diagnosis And Treatment ◽  
Economic Losses ◽  
Reproductive Efficiency ◽  
Ovarian Cysts ◽  
Calving Interval ◽  
Estrus Cycle ◽  
Reproductive Disorders ◽  
South Of Brazil

Reproductive efficiency of dairy cows is evaluated directly considering the calving interval, which is affected by nutrition, irregular estrus cycle, prolonged anestrus, and reproductive diseases. Reproductive diseases cause economic losses due to diagnosis and treatment costs, and reduction in milk production. Thus, the objective of this study was to report the occurrence of the main reproductive disorders in dairy cows of the Southwest of Paraná, South of Brazil. Data of ultrasound diagnoses were collected from 2274 cows of 70 rural properties in the municipalities of Realeza, Planalto, Capanema, Pérola do Oeste, and Santa Isabel do Oeste from January 2014 to May 2015. Reproductive disorders were found in 24.50% (557/2274) of the animals evaluated; ovarian cysts (follicular, and luteal) were the most significant disorders, found in 16.13% (367/2274) of the cases. Other disorders were found less frequently. The occurrence of follicular and luteal cysts was observed especially in primiparous animals in months of pasture transition.

scholarly journals Metabolic Adaptations to Dynamic Energy Requirements during Lactation and Pregnancy in Dairy Cows with Varying Proportions of Holstein and Simmental Breed

Proceedings ◽  
2020 ◽  
Vol 73 (1) ◽  
pp. 9
Author(s):  
Deise Aline Knob ◽  
André Thaler Neto ◽  
Helen Schweizer ◽  
Anna Weigand ◽  
Roberto Kappes ◽  
...  
Keyword(s):  
Energy Balance ◽  
Dairy Cows ◽  
Fixed Effects ◽  
Mixed Model ◽  
Negative Energy ◽  
Negative Energy Balance ◽  
Repeated Measure ◽  
Holstein Cows ◽  
Mixed Model Analysis ◽  
Genetic Groups

Depending on the breed or crossbreed line, cows have to cope with a more or less severe negative energy balance during the period of high milk yields in early lactation, which can be detected by beta-hydroxybutyrate (BHBA) and non-esterified fatty acids (NEFAs) in blood. Preventing cows from undergoing a severe negative energy balance by breeding and/or feeding measures is likely to be supported by the public and may help to improve the sustainability of milk production. The aim was to compare BHBA and NEFA concentrations in the blood of Holstein and Simmental cows and their crosses during the prepartum period until the end of lactation. In total, 164 cows formed five genetic groups according to their theoretic proportion of Holstein and Simmental genes as follows: Holstein (100% Holstein; n = 9), R1-Hol (51–99% Holstein; n = 30), F1 crossbreds (50% Holstein, 50% Simmental; n = 17), R1-Sim (1–49% Holstein; n = 81) and Simmental (100% Simmental; n = 27). NEFA and BHBA were evaluated once a week between April 2018 and August 2019. A mixed model analysis with fixed effects breed, week (relative to calving), the interaction of breed and week, parity, calving year, calving season, milking season, and the repeated measure effect on cows was used. Holstein cows had higher NEFAs (0.196 ± 0.013 mmol/L), and Simmental cows had the lowest NEFA concentrations (0.147 ± 0.008 mmol/L, p = 0.03). R1-Sim, F1 and R1-Hol cows had intermediate values (0.166 ± 0.005, 0.165 ± 0.010, 0.162 ± 0.008 mmol/L; respectively). The highest NEFA value was found in the first week after calving (0.49 ± 0.013 mmol/L). BHBA did not differ among genetic groups (p = 0.1007). There was, however, an interaction between the genetic group and week (p = 0.03). While Simmental, R1-Sim and F1 cows had the highest BHBA value, the second week after calving (0.92 ± 0.07 and 1.05 ± 0.04, and 1.10 ± 0.10 mmol/L, respectively), R1-Hol and Holstein cows showed the BHBA peak at the fourth week after calving (1.16 ± 0.07 and 1.36 ± 0.12 mmol/L, respectively). Unexpectedly, Holstein cows had a high BHBA peak again at week 34 after calving (1.68 ± 0.21 mmol/L). The genetic composition of the cows affects NEFA and BHBA. Simmental and R1-Sim cows mobilize fewer body reserves after calving. Therefore, dairy cows with higher degrees of Simmental origin might be more sustainable in comparison with Holstein genetics in the present study.

scholarly journals The Capacity of Holstein-Friesian and Simmental Cows to Correct a Negative Energy Balance in Relation to Their Performance Parameters, Course of Lactation, and Selected Milk Components

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1674
Author(s):  
Ilona Strączek ◽  
Krzysztof Młynek ◽  
Agata Danielewicz
Keyword(s):  
Fatty Acid ◽  
Energy Balance ◽  
Dairy Cows ◽  
Body Condition ◽  
Body Condition Score ◽  
Negative Energy ◽  
Negative Energy Balance ◽  
Holstein Friesian ◽  
Condition Score ◽  
Peak Lactation

A significant factor in improving the performance of dairy cows is their physiological ability to correct a negative energy balance (NEB). This study, using Simmental (SIM) and Holstein-Friesian (HF) cows, aimed to assess changes in NEB (non-esterified fatty acid; body condition score; and C16:0, C18:0, and C18:1) and its effect on the metabolic efficiency of the liver (β-hydroxybutyrate and urea). The effects of NEB on daily yield, production at peak lactation and its duration, and changes in selected milk components were assessed during complete lactation. Up to peak lactation, the loss of the body condition score was similar in both breeds. Subsequently, SIM cows more efficiently restored their BCS. HF cows reached peak lactation faster and with a higher milk yield, but they were less able to correct NEB. During lactation, their non-esterified fatty acid, β-hydroxybutyrate, C16:0, C18:0, C18:1, and urea levels were persistently higher, which may indicate less efficient liver function during NEB. The dynamics of NEB were linked to levels of leptin, which has anorectic effects. Its content was usually higher in HF cows and during intensive lactogenesis. An effective response to NEB may be exploited to improve the production and nutritional properties of milk. In the long term, it may extend dairy cows’ productive life and increase lifetime yield.

The use of regression techniques on calorimetric data to estimate the metabolisable energy requirements of lactating dairy cows

1997 ◽  
Vol 1997 ◽  
pp. 4-4
Author(s):  
T. Yan ◽  
F. J. Gordon ◽  
R. E. Agnew ◽  
M. G. Porter ◽  
D. C. Patterson
Keyword(s):  
Dairy Cows ◽  
Open Circuit ◽  
Energy Requirements ◽  
Gaseous Exchange ◽  
Calorimetric Data ◽  
Grass Silage ◽  
Lactating Dairy Cows ◽  
Holstein Friesian ◽  
Regression Techniques ◽  
Metabolisable Energy

The metabolisable energy (ME) requirement for maintenance (MEm) can be determined by measuring the fasting metabolism of the non-lactating cow, but this approach cannot encompass any differences in maintenance metabolic rate between lactating and non-lactating animals. The MEm and efficiency of ME use for lactation (k1) can also be estimated by regression of energy outputs against ME intake (MEI). During 1992 to 1995, a total of 221 Holstein/Friesian lactating dairy cows, which were offered grass silage-based diets, were subjected to gaseous exchange measurements in indirect open-circuit respiration calorimeters. The objective of the present study was to use these data to predict the MEm and k1 by a range of regression techniques for lactating dairy cows offered grass silage-based diets.

Effect of concentrate to silage ratio and hoof trimming on lameness in dairy cows

1997 ◽  
Vol 1987 ◽  
pp. 30-30
Author(s):  
Felicity J Manson ◽  
J D Leaver
Keyword(s):  
Dairy Cows ◽  
Animal Welfare ◽  
Preventative Measure ◽  
Predisposing Factor ◽  
Economic Implications ◽  
Two Factors

Lameness in dairy cows has both important animal welfare and economic implications. High concentrate to silage ratios may be an important predisposing factor, whilst trimming has been advocated as an effective preventative measure. This trial examined the effects of these two factors on locomotion, incidence of lameness and hoof measurements.

Glycogenic induction of thyroid hormone conversion and leptin system activation in the liver of postpartum dairy cows

2009 ◽  
Vol 57 (1) ◽  
pp. 139-146
Author(s):  
Andrea Győrffy ◽  
Mónika Keresztes ◽  
Vera Faigl ◽  
Vilmos Frenyó ◽  
Margit Kulcsár ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Energy Balance ◽  
Dairy Cows ◽  
Energy Homeostasis ◽  
Leptin Receptor ◽  
Energy Content ◽  
Short Form ◽  
Negative Energy ◽  
Type I ◽  
Leptin System

In the regulation of energy metabolism, the liver plays an important role in the reinforcement of energy production. In periparturient cows the energy homeostasis turns into a negative energy balance that may shift the physiological regulation of energy balance towards pathological processes. Propylene glycol (PG), as a complementary source of energy used in the nutrition of dairy cows, alters systemic thyroid hormone economy; however, the exact mechanism through which highly glycogenic feed supplements impact liver metabolism is little known. Previous studies showed that only leptin receptors are expressed in the liver of cows, and now we report that leptin mRNA is expressed in the liver of cows as well. The present results show that the mRNA of leptin and its receptors are differentially modulated by the increased energy content of the feed consumed. Simultaneous changes in hepatic type I deiodinase activity suggest that hepatic modulation of the leptin system by PG supplementation may be mediated by an increased local thyroxine-triiodothyronine conversion. Since PG supplementation with simultaneous T4–T3 turnover and increased hepatic leptin- and short-form leptin receptor mRNA were not associated with a significant change in hepatic total lipid levels, it is suggested that the leptin system, directly or indirectly modulated by thyroid hormones, may represent a local defence mechanism to prevent fatty liver formation.

scholarly journals Seroprevalensi Brucellosis dan Tingkat Gangguan Reproduksi Pada Sapi Perah di Kota Batu

2020 ◽  
Vol 4 (1) ◽  
pp. 14-19
Author(s):  
Ani Setianingrum ◽  
Mira Fatmawati ◽  
Aulia Firmawati ◽  
Dahliatul Qosimah ◽  
Fidi Nur Aini E P Dameanti ◽  
...  
Keyword(s):  
Data Analysis ◽  
Dairy Cows ◽  
Statistical Test ◽  
Reproductive Disorders ◽  
Serum Samples ◽  
Chi Square ◽  
Cross Sectional ◽  
Repeated Mating ◽  
The Relationship ◽  
The Rose

This study aimed to measure the incidence rate of brucellosis in dairy cattle at Batu City based onserological tests (seroprevalence) and to determine the relationship between the incidence ofbrucellosis and reproductive disorders. Cross-sectional epidemiological research was conducted todetermine the prevalence of brucellosis in dairy cows. Serum samples were obtained from 130dairy cows over 6 months of age, reproductive disorders data using a questionnaire on 21 farmers.Serological testing used the Rose Bengal Test (RBT) and continued with the Complement FixationTest (CFT). The data analysis used Pearson's Chi-Square correlation statistical test. Theseroprevalence of brucellosis at Batu City was 0.7%. The prevalence of reproductive disorders indairy cows was 29.2% consisted of 8.5% abortion and 20.8% repeated mating. There was acorrelation between brucellosis and the incidence of abortion (2 = 10.90; P<0.05) and a correlation between the incidence of abortion and the age more than 3 years (2 = 5.35; P<0.05). The conclusion of this study showed that the prevalence of brucellosis at Batu city was low (<2%).The results of this study could be used as the basis for implementing a vaccination program anderadicating brucellosis at East Java

scholarly journals Worldline numerics applied to custom Casimir geometry generates unanticipated intersection with Alcubierre warp metric

2021 ◽  
Vol 81 (7) ◽  
Author(s):  
Harold White ◽  
Jerry Vera ◽  
Arum Han ◽  
Alexander R. Bruccoleri ◽  
Jonathan MacArthur
Keyword(s):  
Energy Density ◽  
Three Dimensional ◽  
Casimir Energy ◽  
Negative Energy ◽  
Vacuum Model ◽  
Energy Density Distribution ◽  
Dynamic Vacuum ◽  
Negative Energy Density ◽  
Funded Project ◽  
Transient Electric Field

AbstractWhile conducting analysis related to a DARPA-funded project to evaluate possible structure of the energy density present in a Casimir cavity as predicted by the dynamic vacuum model, a micro/nano-scale structure has been discovered that predicts negative energy density distribution that closely matches requirements for the Alcubierre metric. The simplest notional geometry being analyzed as part of the DARPA-funded work consists of a standard parallel plate Casimir cavity equipped with pillars arrayed along the cavity mid-plane with the purpose of detecting a transient electric field arising from vacuum polarization conjectured to occur along the midplane of the cavity. An analytic technique called worldline numerics was adapted to numerically assess vacuum response to the custom Casimir cavity, and these numerical analysis results were observed to be qualitatively quite similar to a two-dimensional representation of energy density requirements for the Alcubierre warp metric. Subsequently, a toy model consisting of a 1 $$\upmu $$ μ m diameter sphere centrally located in a 4 $$\upmu $$ μ m diameter cylinder was analyzed to show a three-dimensional Casimir energy density that correlates well with the Alcubierre warp metric requirements. This qualitative correlation would suggest that chip-scale experiments might be explored to attempt to measure tiny signatures illustrative of the presence of the conjectured phenomenon: a real, albeit humble, warp bubble.

scholarly journals THE NUTRITIONAL BALANCE OF EARLY LACTATION DAIRY COWS GRAZING IN INTENSIVE SILVOPASTORAL SYSTEMS

2017 ◽  
Vol 18 (0) ◽  
Author(s):  
Elisa Sierra Montoya ◽  
Julian David Chará ◽  
Rolando Barahona-Rosales
Keyword(s):  
Dairy Cows ◽  
Negative Energy ◽  
Protein Supplementation ◽  
Metabolizable Energy ◽  
Early Lactation ◽  
Tropical Conditions ◽  
Forage Intake ◽  
Daily Milk Yield ◽  
To Receive ◽  
Daily Milk

Abstract A study was carried out to estimate the balance of metabolizable protein (MP), metabolizable energy (ME), calcium, and phosphorus in 12 recently calved (RC) and early lactation (EL, 42 - 50 days after calving) Gyr x Holstein dairy cows grazing in a Leucaena leucocephala and Cynodon plectostachyus intensive silvopastoral system (ISS) and receiving energy and protein supplementation. Dry matter (DM) availability from the grazing paddocks, nutrients offered and their balance were estimated. On average, the available forage DM per animal.day-1 was 44.7 kg for C. plectostachyus and 11.8 kg for L. leucocephala. EL cows had greater requirements of MP, ME, and minerals than RC cows. In RC cows, ME, MP, and mineral requirements were supplied by the total diet, while EL cows exhibited a negative energy balance. For both RC and EL cows, ME was the limiting dietary factor, whereas MP and P were found to be in excess. If cows were only to receive ISS forages with no supplementation, estimated daily milk yield would be 10 and 12 litters for RC and EL cows, respectively. Under tropical conditions, based on ISS forage intake, RC and EL cows can meet most of their ME, MP, calcium, and phosphorous requirements.

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