Coexistence of Osteoporosis and Cardiovascular Disease Risk Factors in Apparently Healthy, Untreated Postmenopausal Women

2005 ◽  
Vol 75 (2) ◽  
pp. 97-106 ◽  
Author(s):  
Massé ◽  
Tranchant ◽  
Dosy ◽  
Donovan

This study aimed to determine whether apparently healthy, untreated postmenopausal women at risk of osteoporosis relative to nonmenopausal women are concomitantly at risk of cardiovascular disease (CVD) in terms of various aspects of lifestyle, personality, body shape and composition, and blood chemistry. Two homogeneous groups of 30 women having reached menopause for 3–5 years and 30 nonmenopausal controls, all non-estrogen users without apparent CVD risk factors, were compared in a cross-sectional design. Data related to physical activity, dietary intakes, personality type, anthropometry, and skinfold-thickness were collected. Plasma insulin-like growth factor (IGF-1) and serum lipids were measured and used as biochemical predictors of osteoporosis and CVD, respectively. Compared to nonmenopausal controls, postmenopausal women were at greater risk of bone loss given their lower plasma IGF-1, lower physical activity level, and even given their higher serum lipids, as recent literature suggests. Moreover, their dietary calcium intake fulfilled only 70% of the current recommendation, which may reduce protection against osteoporosis and CVD (particularly hypertension) as well. The two groups did not differ regarding energy intake, body weight and frame size, body mass index (BMI), waist circumference, and waist-hip ratio (WHR). However, postmenopausal subjects had more adipose tissue and differed in terms of lifestyle factors (lower dietary lipids and greater alcohol consumption). While neither group was at particular risk of CVD according to waist circumference, WHR, and serum triglycerides, postmenopausal women were at risk according to percent body adiposity and serum cholesterol. This study shows that several risk factors for osteoporosis and CVD can coexist in apparently healthy postmenopausal women after a few years of natural menopause. It emphasizes the need for a timely screening that would stress both heart and bone risk factors.

Author(s):  
Mette Aadahl ◽  
Michael Kjær ◽  
Torben Jørgensen

Introduction Sedentary behaviour, especially TV viewing, has been identified as a possible risk factor for cardiovascular disease, whereas physical activity seems to protect against major cardiovascular risk factors: obesity, dyslipidemia and hypertension. The aim of this study was to explore the association between both time spent on TV viewing and vigorous intensity physical activity in relation to body mass index, waist circumference, waist/hip ratio, serum lipids and blood pressure. Methods A total of 1693 men and women, 33-64 years of age, from the 3-year follow-up of a population-based intervention study, The Inter 99 study, were included in this cross-sectional design. Information on TV viewing, physical activity and other lifestyle habits was obtained by self-report questionnaire. Associations between TV viewing/physical activity and biological cardiovascular risk factors were explored by multiple linear regression analyses. Results Data from 835 (51%) men and 805 (49%) women were included. Mean age was 50.8 years (33.0-64.6). Men had a higher overall physical activity score than women ( P < 0.0001). TV viewing was significantly, positively associated with waist/hip ratio ( P = 0.005), body mass index ( P = 0.03), triglycerides ( P = 0.005), low density lipoprotein cholesterol ( P = 0.03), total cholesterol ( P = 0.01), systolic ( P = 0.05) and diastolic blood pressure ( P = 0.03), but not with waist circumference and high density lipoprotein cholesterol (HDL). Engaging in vigorous intensity physical activity was associated with higher HDL ( P = 0.0006) and lower waist circumference ( P < 0.0001). Conclusion TV viewing and physical activity should be regarded as separate types of behaviour that relate to different cardiovascular disease risk factors. Eur J Cardiovasc Prev Rehabil 14:660-665 © 2007 The European Society of Cardiology


1997 ◽  
Vol 82 (2) ◽  
pp. 652-660 ◽  
Author(s):  
Edith T. Stevenson ◽  
Kevin P. Davy ◽  
Pamela P. Jones ◽  
Christopher A. Desouza ◽  
and Douglas R. Seals ◽  
...  

Stevenson, Edith T., Kevin P. Davy, Pamela P. Jones, Christopher A. Desouza, and Douglas R. Seals. Blood pressure risk factors in healthy postmenopausal women: physical activity and hormone replacement. J. Appl. Physiol. 82(2): 652–660, 1997.—The prevalence of cardiovascular disease (CVD) increases with advancing age in women, particularly after menopause. CVD risk is lower in physically active women relative to their sedentary peers, but the responsible mechanisms are not well understood. The aims of this study were to test the hypotheses that 1) physically active postmenopausal women demonstrate more favorable blood pressure (BP)-related risk factors for CVD than do sedentary healthy women and 2) women on hormone replacement therapy (HRT) also have more favorable levels of these CVD risk factors. BP-related CVD risk factors were measured in physically active women ( n = 18; age 55 ± 1 yr; n = 8 on HRT) and in healthy less-active controls ( n = 34; age 59 ± 1 yr; n = 17 on HRT). Maximal oxygen consumption was higher in the active group, whereas waist-to-hip ratio and waist circumference were lower (all P < 0.005). The active women demonstrated marginally lower (5–8 mmHg; P ≤ 0.10) levels of casual, 24-h, and daytime systolic BP (SBP). They also tended to have lower ( P = 0.11) daytime SBP loads (percentage of BP recordings >140/90 mmHg) and lower daytime and nighttime BP variabilities ( P = 0.04) and a reduced ( P < 0.007) SBP response to submaximal exercise. Women on HRT tended to have lower (3–4 mmHg; P = 0.07) levels of 24-h and nighttime diastolic BP (DBP) relative to the nonusers and smaller ( P < 0.04) daytime and 24-h DBP loads. Stepwise multiple regression indicated that waist circumference was the primary predictor of most of the SBP-related CVD risk factors while HRT use was the best predictor for DBP loads. These findings indicate that, in general, physically active postmenopausal women demonstrate more favorable SBP-related CVD risk factors relative to their less-active healthy peers, which may be mediated, in part, by their lower levels of abdominal adiposity. In addition, HRT use tends to be associated with lower levels of DBP-related CVD risk factors.


2009 ◽  
Vol 12 (6) ◽  
pp. 816-824 ◽  
Author(s):  
Yin Ruixing ◽  
Yang Dezhai ◽  
Li Shuquan ◽  
Chen Yuming ◽  
Yang Hanjun ◽  
...  

AbstractObjectiveTo compare the differences in hyperlipidaemia prevalence and its risk factors between the Guangxi Bai Ku Yao and Han populations.DesignCross-sectional study of hyperlipidaemia.SettingBoth populations were from Lihu and Baxu villages in Nandan County, Guangxi Zhuang Autonomous Region, People’s Republic of China.SubjectsA total of 1170 healthy subjects of Bai Ku Yao and 1173 participants of Han Chinese aged 15–89 years were surveyed by a stratified randomized cluster sampling. Information on demographic, dietary and lifestyle characteristics was collected by standard questionnaires. Blood pressure, height, weight, waist circumference, serum lipids and apolipoproteins were measured, and BMI (kg/m2) was calculated as weight divided by the square of height.ResultsThe prevalence rates of hypercholesterolaemia, hypertriacylglycerolaemia and hyperlipidaemia in Bai Ku Yao and Han were 12·4 % v. 26·2 % (P < 0·001), 15·0 % v. 14·8 % (P > 0·05) and 24·4 % v. 33·9 % (P < 0·001), respectively. Hyperlipidaemia was positively correlated with BMI, waist circumference, total energy and total fat intakes, and negatively associated with physical activity and total dietary fibre intake in Bai Ku Yao (P < 0·05 to 0·001). Hyperlipidaemia was positively associated with age, alcohol consumption, BMI, waist circumference, total energy and total fat intakes, and inversely correlated with physical activity and total dietary fibre intake in Han (P < 0·05 to 0·001).ConclusionsThe prevalence of hypercholesterolaemia and hyperlipidaemia was significantly lower in the Bai Ku Yao than in the Han population, which might result from different dietary habits, lifestyle choices and physical activity level, as well as genetic factors between the two ethnic groups.


2021 ◽  
Author(s):  
Charrlotte Seib ◽  
Stephanie Moriarty ◽  
Nicole McDonald ◽  
Debra Anderson ◽  
Joy Parkinson

Abstract Background Chronic disease is the leading cause of premature death globally, and many of these deaths are preventable by modifying some key behavioural and metabolic risk factors. This secondary data analysis examines changes in health behaviours among men and women at risk of diabetes or cardiovascular disease (CVD) who participated in a 6-month lifestyle intervention called the My health for life program. Methods My health for life is a government-funded multi-component program designed to reduce chronic disease risk factors amongst at-risk adults. The intervention comprises six sessions over a 6-month period, delivered by a trained facilitator or telephone health coach. The analysis presented in this paper stems from 9,372 participants who participated in the program between July 2017 and December 2019. Primary outcomes included fruit and vegetable intake, consumption of sugar-sweetened drinks and take-away, alcohol and tobacco smoking, physical activity, body mass index (BMI), and waist circumference (WC). Variables were summed to form a single Healthy Lifestyle Index (HLI) ranging from 0 to 18, with higher scores denoting healthier behaviours. Longitudinal associations between lifestyle indices, assessed using Gaussian Generalized Estimating Equations (GEE) models with an identity link and robust standard errors. Results Improvements in HLI scores were noted between baseline (Md = 10.0; IQR = 8.3, 11.7] and 26-weeks (Md = 11.7; IQR = 10.0, 13.2] which corresponded with increases in fruit and vegetable consumption and decreases in takeaway frequency, and weight indices (p < .01 for all) but not risky alcohol intake. Modelling showed higher average HLI among those aged 45 or older (β = 0.97, 95% CI = 0.81, 1.13, p < .01) with vocational educational qualifications (certificate/diploma: β = 0.47, 95% CI = 0.19, 0.76, p < .01; bachelor/post-graduate degree β = 1.05, 95% CI = 0.76, 1.34, p < .01) while being male, Aboriginal or Torres Strait Islander background, or not currently working conferred lower average HLI scores (p < .01 for all). Conclusions While participants showed improvements in many healthy lifestyle indices including BMI, waist circumference, physical activity, and dietary indicators, changes in alcohol consumption were less amenable to the program. There is a need for additional research to understand the multi-level barriers and facilitators of behaviour change in this context to tailor the intervention for more-difficult-to-treat groups.


2016 ◽  
Vol 18 (1) ◽  
pp. 26-36 ◽  
Author(s):  
Rita De Cássia Spanhol ◽  
Carlos Kusano Bucalen Ferrari

<p>To evaluate the frequency of obesity and lifestyle risk factors in the population of Barra do Garças, Legal Amazon.</p><p><strong>Methodology </strong>A randomized, transversal study with 305 adults of both genders was performed. Weight, height, body mass index (BMI), waist circumference, food dietary habits, frequency of smoking and alcoholic consumption, practice of physical activity, and the physical activity level were evaluated.  </p><p><strong>Results </strong>Smoking and alcoholic consumption was higher among men compared to women. Almost 60 % of men engaged in leisure-time physical activities, whereas only 42.4 % of women practiced physical activity. Women were engaged in mostly sedentary behavior activities, such as watching television and using the computer use than men. Dietary daily intake of fruits and vegetables were higher among women compared to men (65.9 % and 51.5 %, respectively). Men were more prone to drink soft drinks than women. However, 39.4 % of men and only 3.4 % of women drank soft drinks three or more days <em>per</em> week. The prevalence of overweight and obesity according to body mass index (BMI) was higher in this study. 34.4 % of men and 33.7 % of women were overweight and 15.10 % and 17.50% of men and women, respectively, were classifyied as obese. Elevated values of waist circumference were found in 35.35 % of men and 70.73 % of women.</p><p><strong>Conclusión</strong> Women were more sedentary than men and had higher prevalence of abnormal waist circumference values.</p>


Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Nse A Odunaiya ◽  
Quinette A Louw ◽  
Karen Grimmer-sommers

Cardiovascular disease (CVD) is a global health problem. Studies have shown that the majority of people dying from CVD have one or more major risk factors that are influenced by lifestyle. Major predisposing risk factors include obesity, physical inactivity, abdominal obesity. These risk factors have been seen in adolescents in developed countries. Throughout the world the risks are starting to appear earlier. Adolescence is a critical temporal window for the development of obesity in adult age. Researchers have advocated that children and adolescent populations should be the target for cardiovascular risk factors prevention programs, however, there is paucity of information on these risk factors especially among rural adolescents. It is a general belief in Nigeria that rural dwellers are active, consume natural foods as such CVD and other chronic diseases may not be highly prevalent among rural people However, primordial prevention for cardiovascular is needed even in rural communities since prevention is better than cure. The study aimed to ascertain selected CVD risk factors such as physical activity level, BMI Waist Hip ratio and dietary pattern of adolescents in rural Nigeria The study was a cross sectional survey of 1079 adolescents aged 15-18 years, attending schools at Ibarapa central local government of South West Nigeria. Ethical approval was sought and obtained from Stellenbosch University ethics committee, approval from the local Education authority and principals of the selected schools. Informed consent was obtained from the principals of the schools who acted in place of the parents and guardians who were not in the community and also from parents within the community. Assent was obtained from adolescents either written or verbal. CVD risk factors were assessed using standard measures .Result shows 23% of adolescents are underweight, 75% normal weight and 1.4% overweight. Waist hip ratio of 84.6% of adolescents are normal, 15.4% abdominal obesity, for physical activity level; 27.9% had low physical activity level, 36.5% moderate physical activity level and 35.6% high physical activity level. More female had low activity level compared to male, 63.5% compared to 36.5% The adolescents generally have bad dietary pattern such as high fat consumption, low fruit and vegetable intake Underweight is still a major problem among rural adolescents. Many of the rural adolescents are not active enough to safeguard their future health. Sedentary living is more among female than male. Although these rural adolescents are not generally obese but there is a high prevalence of abdominal obesity, low fruit and vegetable consumption which is associated with cardiovascular disease Implication; there is need for CVD primordial and primary prevention program for Nigerian rural adolescents


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