The PREVIEW Study

2019 ◽  
Vol 26 (1) ◽  
pp. 10-20
Author(s):  
Maija Huttunen-Lenz ◽  
Sylvia Hansen ◽  
Thomas Meinert Larsen ◽  
Pia Christensen ◽  
Mathijs Drummen ◽  
...  

Abstract. Individuals at risk of Type 2 Diabetes are advised to change health habits. This study investigated how the PREMIT behavior modification intervention and its association with socio-economic variables influenced weight maintenance and habit strength in the PREVIEW study. Overweight adults with pre-diabetes were enrolled ( n = 2,224) in a multi-center RCT including a 2-month weight-loss phase and a 34-month weight-maintenance phase for those who lost ≥ 8% body weight. Initial stages of the PREMIT covered the end of weight-loss and the beginning of weight-maintenance phase (18 weeks). Cross-sectional and longitudinal data were explored. Frequent PREMIT sessions attendance, being female, and lower habit strength for poor diet were associated with lower weight re-gain. Being older and not in employment were associated with lower habit strength for physical inactivity. The PREMIT appeared to support weight loss maintenance. Younger participants, males, and those in employment appeared to struggle more with inactivity habit change and weight maintenance.

2021 ◽  
Vol 8 ◽  
Author(s):  
Marleen A. van Baak ◽  
Gabby Hul ◽  
Arne Astrup ◽  
Wim H. Saris

In this secondary analysis of the DiOGenes study, we investigated whether physical activity (PA) contributes to diet-induced weight loss and helps to reduce subsequent regain. We also studied the associations of PA with changes in cardiometabolic variables. Adults with overweight were included and followed an 8-week low-calorie diet (LCD). When successful (>8% weight loss), participants were randomized to different ad libitum diet groups and were advised to maintain their weight loss over the 6-month intervention period. Body weight (BW), body composition, cardiometabolic variables and subjectively-assessed PA were measured at baseline, at the end of weight loss and at the end of the intervention. BW was reduced by the LCD (from 99.8 ± 16.7 to 88.4 ± 14.9 kg; P < 0.001). This reduction was maintained during the weight maintenance period (89.2 ± 16.0 kg). Total PA (sum score of the three subscales of the Baecke questionnaire) increased during the weight loss period (from 8.16 ± 0.83 to 8.39 ± 0.78; P < 0.001) and this increase was subsequently maintained (8.42 ± 0.90). We found no evidence that baseline PA predicted weight loss. However, a higher level of baseline PA predicted a larger weight-loss-induced improvement in total cholesterol, triglycerides, glucose and CRP, and in post-prandial insulin sensitivity (Matsuda index). Subsequent weight and fat mass maintenance were predicted by the post-weight loss level of PA and associated with changes in PA during the weight maintenance phase. In conclusion, despite the fact that higher baseline levels of PA did not predict more weight loss during the LCD, nor that an increase in PA during the LCD was associated with more weight loss, higher PA levels were associated with more improvements in several cardiometabolic variables. The positive effect of higher PA on weight loss maintenance seems in contrast to randomized controlled trials that have not been able to confirm a positive effect of exercise training programmes on weight loss maintenance. This analysis supports the notion that higher self-imposed levels of PA may improve the cardiometabolic risk profile during weight loss and help to maintain weight loss afterwards.


2012 ◽  
Vol 108 (8) ◽  
pp. 1466-1474 ◽  
Author(s):  
Irene A. Munro ◽  
Manohar L. Garg

Obesity is associated with elevated levels of inflammation and metabolic abnormalities which are linked to CVD. The aim of the present study was to investigate whether long-chain n-3 PUFA (LCn-3PUFA), combined with a very-low-energy diet (VLED), facilitated weight loss and weight maintenance, and improvements in blood lipids and inflammatory mediators. This was a double-blind, randomised, controlled trial with two parallel groups. For 14 weeks, one group consumed 6 × 1 g capsules/d of monounsaturated oil (placebo group, PB), and the other group consumed 6 × 1 g capsules/d of LCn-3PUFA (fish oil group, FO), each comprising 70 mg EPA and 270 mg DHA. Both groups were on VLED for 4 weeks (n 14 PB, n 18 FO), which was then followed by 10 weeks of weight maintenance (n 12 PB, n 17 FO). Fasting blood samples, anthropometric measurements and 3 d food diaries were collected at baseline, at 4 and 14 weeks. A greater-than-2-fold increase occurred in plasma levels of EPA and DHA in the FO group (P < 0·001). At 4 weeks, the mean weight loss was − 6·54 (sd 2·08) kg ( − 6·9 %) for PB and − 6·87 (sd 1·83) kg ( − 7·7 %) for FO. At week 14, after the maintenance phase, there was a further mean decrease in weight, − 1·57 (sd 3·7) kg (1·85 %) for PB and − 1·69 (sd 2·32) kg ( − 1·9 %) for FO. Both groups experienced improved metabolic profiles and there was a significant reduction in fat mass for the FO group at week 14 but not for PB. However, it would appear that supplementation with LCn-3PUFA had no significant effect on weight loss or weight maintenance over the 14 weeks.


Author(s):  
Carlos Albuquerque ◽  
Carla Correia ◽  
Sara Oliveira Albuquerque

Objectives: To determine the adherence to physical activity among people with type 2 diabetes Methods: Quantitative, cross-sectional, nonexperimental, descriptive, and correlational study, with a sample of 102 people suffering from type 2 diabetes whose age ranged between 40 and 85 years. Most of the participants were male (51.96%). The evaluation protocol included a sociodemographic and clinical questionnaire, Diabetes Self-Care Scale(1) and the Diabetes Knowledge Questionnaire(2). The HbA1c clinical parameter was used to directly assess adherence. Results: The self-care activity in which respondents showed higher level of involvement was glucose monitoring that had an average participation of 5.73 days per week. Inversely, participants did not seem interested in physical activity. In this sort of activity participation amounted to 1 mere day per week on average. The study also showed that people with type 2 diabetes show minimal knowledge of areas related to the identity of the illness, its causes, complications, and treatment. 53.9% of the respondents did not recognise the role played by physical exercise in the treatment of their condition. Conclusion: Reducing the incidence of this disease is an imperative and preventive measure must be implemented to prevent the appearance of the problem, especially for people at higher risk. Among all the possible measures to be implemented, special focus will have to be placed on physical activity and weight loss. Physical activity has a direct impact on the control of the disease through the reduction of HbA1c levels, but its influence is also evident in other parameters, like weight loss, prevention of risk factors for cardiovascular diseases and it also plays a crucial role in increasing quality of life.


PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0160774 ◽  
Author(s):  
Kirsten A. Berk ◽  
Monique T. Mulder ◽  
Adrie J. M. Verhoeven ◽  
Herman van Wietmarschen ◽  
Ruud Boessen ◽  
...  

Author(s):  
Kristy L. Gray ◽  
Lois McKellar ◽  
Sharleen L. O’Reilly ◽  
Peter M. Clifton ◽  
Jennifer B. Keogh

Weight loss after gestational diabetes (GDM) reduces the risk of type 2 diabetes (T2DM); however, weight loss remains challenging in this population. In order to explore perceptions of T2DM risk, barriers to weight loss, and views of diet strategies in women with previous GDM, a cross-sectional online survey of n = 429 women in Australia aged ≥18 years with previous GDM was conducted. Opinions of intermittent energy restriction (IER) were of interest. Seventy-five percent of responders (n = 322) had overweight or obesity, and 34% (n = 144) believed they had a high risk of developing T2DM. Within the Theoretical Domains Framework, barriers to weight loss were prominently related to Environmental Context and Resources, Beliefs about Capabilities, and Behavioural Regulation. Exercising was the most tried method of weight loss over other diet strategies (71%, n = 234) and weight loss support by a dietician was appealing as individual appointments (65%, n = 242) or an online program (54%, n = 200). Most women (73%, n = 284) had heard of IER (the “5:2 diet”), but only 12% (n = 34) had tried it. Open comments (n = 100) revealed mixed views of IER. Women in Australia with previous GDM were found to lack a self-perceived high risk of developing T2DM and expressed barriers to weight loss related to their family environment, beliefs about their capabilities and behavioural regulation. IER is appealing for some women with previous GDM; however, views vary.


Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1643
Author(s):  
Shaheen Tomah ◽  
Ahmed H. Eldib ◽  
Mhd Wael Tasabehji ◽  
Joanna Mitri ◽  
Veronica Salsberg ◽  
...  

Dairy products are integral parts of healthy diets; however, their association with cardiometabolic (CM) health among patients with type 2 diabetes (T2D) undergoing weight management is debated. We examined the relationship between dairy consumption and CM biomarkers in 45 subjects with T2D and obesity (mean age 56 ± 9 yrs, 40% female) enrolled in a 12-week intensive multidisciplinary weight management (IMWM) program. After the IMWM program (intervention phase), subjects were followed for 12 weeks (maintenance phase). We stratified subjects based on initial average dairy consumption into infrequent (IFR), less-frequent (LFR), and frequent (FR) consumers. Outcomes were assessed at baseline, 12, and 24 weeks. There were no differences between tertiles at baseline except for higher total energy intake among FR compared with IFR. HbA1c changes showed no association with dairy consumption at 12 or 24 weeks. FR Females achieved greater weight loss at 12 weeks compared with IFR peers (−4.5 kg; 95%CI: −5.5, −3.5). There was a trend towards lower HDL-C with increasing dairy consumption during the intervention phase. In subjects with T2D and overweight or obesity, dairy consumption during weight management is not associated with HbA1c changes but with lower HDL-C and with higher magnitude of weight loss among females.


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