Prevalence and risk factors of hypovitaminosis D in pregnant Spanish women

Abstract The hypovitaminosis D epidemic is a global health problem. Our aim was to assess the prevalence and potential risk factors of hypovitaminosis D among pregnant women on the eastern Mediterranean coast. Cross-sectional analysis involved 793 healthy pregnant women (35.3 ± 5.0 years) participating in ECLIPSES, a multicenter randomized trial. Socio-demographic, obstetric, anthropometric, lifestyle, dietary variables and blood draw was collected in the first trimester. Vitamin D deficiency was identified in 50.2% and insufficiency in 30.3% of pregnant women. The mean vitamin D level in the overall sample was 33.9 nmol/L (SD, 17.0). Multivariable logistic regression analysis applying AIC-based backward selection identified excess weight during the 1st trimester (BMI ≥ 25 kg/m2) (OR = 1.950, 95% CI = 1.409, 2.699), Arab ethnic group/dark skin colour (OR = 4.005, 95% CI = 2.488, 6.447), winter/spring (OR = 4.319, 95% CI = 3.112, 5.994), and consumption of milk (OR = 0.754, 95% CI = 0.572, 0.993) and yogurt (OR = 0.635, 95% CI = 0.436, 0.922) as independent risk factors for vitamin D deficiency. All of these factors (except yogurt consumption) and physical activity were independently associated with vitamin D deficiency/insufficiency risk in the final multivariable model (all p < 0.05). All these factors and social class were the most important determinants of circulating 25(OH)D concentrations. Our results confirm a high prevalence of vitamin D deficiency and insufficiency among pregnant women from the eastern Mediterranean coast.

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Vitamin D Deficiency and Associated Risk Factors in Women from Riyadh, Saudi Arabia

Scientific Reports ◽

10.1038/s41598-019-56830-z ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 1

Author(s):

Nora A. AlFaris ◽

Nora M. AlKehayez ◽

Fatema I. AlMushawah ◽

AbdulRhman N. AlNaeem ◽

Nadia D. AlAmri ◽

...

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Saudi Arabia ◽

Vitamin D Deficiency ◽

Public Awareness ◽

Public Health Problem ◽

Hypovitaminosis D ◽

Cross Sectional Study ◽

Cross Sectional ◽

Associated Risk Factors

AbstractVitamin D deficiency is an epidemic public health problem worldwide. It is common in the Middle East and is more severe in women. This cross-sectional study was conducted to assess vitamin D deficiency and associated risk factors in women living in Riyadh, Saudi Arabia. Serum 25-hydroxyvitamin D (25(OH)D) was measured in 166 women aged 30–65 years. Socio-demographic, lifestyle and health status characteristics, as well as intake of selected dietary supplements, were collected. Weight and height were measured. Vitamin D deficiency (25(OH)D < 20 ng/mL) was reported in 60.2% of participants. Mean of serum 25(OH)D was 20.7 ng/mL. Older age and taking the supplements of vitamin D, multi-vitamins or calcium were identified as factors that associated with a lower risk of hypovitaminosis D. A national strategy is needed to control a hypovitaminosis D crisis in Saudi Arabia. This could be accomplished by raising public awareness regarding vitamin D, regulating and enhancing vitamin D fortification and supplementation and screening vitamin D status among women at high risk.

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25-hydroxyvitamin D status of pregnant women is associated with the use of antenatal vitamin supplements and ambient ultraviolet radiation

Journal of Developmental Origins of Health and Disease ◽

10.1017/s2040174416000143 ◽

2016 ◽

Vol 7 (4) ◽

pp. 350-356 ◽

Cited By ~ 4

Author(s):

A. P. Jones ◽

K. Rueter ◽

A. Siafarikas ◽

E.-M. Lim ◽

S. L. Prescott ◽

...

Keyword(s):

Vitamin D ◽

Pregnant Women ◽

Vitamin D Deficiency ◽

Uv Radiation ◽

South Australia ◽

Cross Sectional Study ◽

Vitamin D Supplementation ◽

Blood Draw ◽

Cross Sectional ◽

Hydroxyvitamin D

Previous research suggests prevalent vitamin D deficiency in pregnant women residing in South Australia and the Eastern Seaboard, however recent data from Perth, Western Australia (WA) is lacking. This cross-sectional study ofn=209 pregnant women (36–40 weeks of gestation, 84% white Caucasian) reports on the vitamin D (25[OH]D) status of a contemporary population of pregnant women in Perth, WA, with a focus on the relative contributions of supplemental vitamin D and ambient ultraviolet (UV) radiation to 25(OH)D levels. Mean (SD) season-adjusted 25(OH)D levels were 77.7 (24.6) nmol/l. The prevalence of vitamin D deficiency (25[OH]D<50 nmol/l) was 13.9%. Ambient UV radiation levels in the 90 days preceding blood draw were significantly correlated with serum 25(OH)D levels (unstandardized coefficient 2.82; 95% CI 1.77, 3.86,P<0.001). Vitamin D supplementation expressed as dose per kg of body weight was also positively correlated with serum 25(OH)D levels (unstandardized coefficient 0.744; 95% CI 0.395, 1.092,P<0.001). In conclusion, this study finds that vitamin D deficiency in a predominantly white Caucasian cohort of pregnant women is less prevalent than has been reported in other studies, providing useful information relating to supplementation and screening in this, and similar, populations.

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Determination of Pregnant women Knowledge toward Risk Factors of Vitamin D Deficiency and Measuring Level During Pregnancy in Al- Nasiriyah City

10.36295/asro.2020.231333 ◽

2020 ◽

Vol 23 (13) ◽

Author(s):

Ali Abdulhakeem Hassan Albakaa ◽

Amer Muhssen Naser ◽

Ali Riyad Saleim

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Pregnant Women ◽

Vitamin D Deficiency

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Analysis of risk factors for vitamin D deficiency by results of the first stage of Russian non-interventional register study

Medical Council ◽

10.21518/2079-701x-2021-7-109-118 ◽

2021 ◽

pp. 109-118

Author(s):

L. A. Suplotova ◽

V. A. Avdeeva ◽

L. Y. Rozhinskaya ◽

E. A. Pigarova ◽

E. A. Troshina

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Russian Federation ◽

Direct Sunlight ◽

Cross Sectional ◽

Wide Range ◽

Smoking Duration

Introduction. In Russian Federation, there are no comprehensive studies assessing the quality of life and risk factors for vitamin D deficiency and insufficiency, taking into account its status in different geographic latitudes.Aim. To assess the quality of life and risk factors for vitamin D deficiency and insufficiency among the population living in the regions of the Russian Federation located at latitudes from 45 ° to 70 °.Materials and methods. The first stage of the Russian multicenter non-interventional registry study using the “cross-sectional” method was carried out from March 2020 to May 2020.Results and discussion. According to the results of the correlation analysis, qualitative and quantitative factors were identified, presumably being risk factors for vitamin D deficiency and deficiency. Qualitative risk factors include: education; alcohol consumption; being in direct sunlight for more than 30 minutes a day; visit to the solarium; using sunscreen; drinking coffee; taking medications (not vitamin-mineral complexes). Quantitative factors include: visits to specialists (total per year); smoking (duration, years); exercise for more than 30 minutes a day, once a week; being in direct sunlight for more than 30 minutes a day.Conclusion. A wide range of risk factors for vitamin D deficiency dictates the need for their further study to clarify the category of persons who are shown targeted biochemical screening with subsequent drug correction.

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Assessment of risk factors associated with vitamin D status among children of an urban and a rural areas of Bangladesh

Bangladesh Medical Research Council Bulletin ◽

10.3329/bmrcb.v46i2.49024 ◽

2020 ◽

Vol 46 (2) ◽

pp. 134-141

Author(s):

Anamika Saha ◽

Md Salim Shakur ◽

Runa Laila ◽

Salomee Shakur ◽

Md Sohel Shomik ◽

...

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Hypovitaminosis D ◽

Urban Children ◽

Outpatient Department ◽

P Value ◽

Rural Children ◽

Vitamin D Status ◽

Factors Associated

Background: Vitamin D deficiency is one of the most common micronutrient deficiency in children worldwide, even in Bangladesh. However, to date, the prevalence of vitamin D deficiency among children of different region of Bangladesh is less reported. Objective: This study was conducted to assess vitamin D status of urban and rural Bangladeshi children including the risk factors associated with vitamin D deficiency are also evaluated. Methods: A multi-centre (urban and rural based), cross sectional study was done from July 2016 to June 2017, using serum 25(OH) vitamin D3 as a marker of nutritional vitamin D status. Urban and rural children were taken from Paediatric Outpatient Department, United Hospital Limited. Dhaka and Medical Outpatient Department, Upazila Health Complex, Ghatail, Tangail respectively. Children of 1-10 years age attending OPD with mild undernutrition (<–1 SD z score) and/or clinical features suggestive of vitamin D deficiency were included in the study. Results: A total 150 children were studied with 102 (68.0%) urban and 48 (32.0%) rural children. Hypovitaminosis D (25-OHD <30ng/ml) was found in 75.0% of children. Hypovitaminosis D was found significantly more in urban children (81.0%) compared to rural (62.0%) children (OR=0.382, 95% CI: 0.177-0.822, p value <0.05). Inadequate exposure to sunlight was significantly associated with hypovitaminosis D compared to adequate sun exposure and it was about 2.5 times higher (OR=2.475, 95% CI: 1.139-5.380, p value <0.05). No significant associations of vitamin D deficiency were detected with skin color of children, covering clothes of mother, exclusive breast feeding, limb pain and anthropometric status. Children of higher educated mother (above Secondary School Certificate) (OR=0.412, 95% CI: 0.189-0.900) were more associated with vitamin D deficiency. Conclusion: Vitamin D deficiency (VDD) is prevalent among Bangladeshi children, urban children being more vulnerable to VDD. Adoption of a screening programme for children of all age group and implementation of preventive strategies for VDD through public health policies are strongly recommended. Bangladesh Med Res Counc Bull 2020; 46(2): 134-141

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The Association of Serum Vitamin D Deficiency and Metabolic Risk Factors in Chinese Adults with Prediabetes: A Cross-Sectional Study

Journal of Nutritional Science and Vitaminology ◽

10.3177/jnsv.65.211 ◽

2019 ◽

Vol 65 (3) ◽

pp. 211-218 ◽

Cited By ~ 2

Author(s):

Li-Qiang TIAN ◽

Wen-Qi SHI ◽

Yang ZHOU ◽

Yu-Wen ZHANG ◽

Mei-Lin ZHANG

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Serum Vitamin ◽

Cross Sectional Study ◽

Metabolic Risk ◽

Sectional Study ◽

Chinese Adults ◽

Cross Sectional ◽

Serum Vitamin D

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High Prevalence of Vitamin D Deficiency in Pregnant Women: A National Cross-Sectional Survey

PLoS ONE ◽

10.1371/journal.pone.0043868 ◽

2012 ◽

Vol 7 (8) ◽

pp. e43868 ◽

Cited By ~ 78

Author(s):

Stefanie Vandevijvere ◽

Sihame Amsalkhir ◽

Herman Van Oyen ◽

Rodrigo Moreno-Reyes

Keyword(s):

Vitamin D ◽

Pregnant Women ◽

Vitamin D Deficiency ◽

Cross Sectional Survey ◽

Cross Sectional ◽

High Prevalence

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VITAMIN D PROVISION FOR CHILDREN AND ADULT POPULATION OF THE AMUR REGION

Bulletin physiology and pathology of respiration ◽

10.12737/20121 ◽

2016 ◽

Vol 1 (60) ◽

pp. 57-61 ◽

Cited By ~ 1

Author(s):

Романцова ◽

Elena Romantsova ◽

Борисенко ◽

Elena Borisenko ◽

Бабцева ◽

...

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Pregnant Women ◽

Vitamin D Deficiency ◽

Respiratory Infections ◽

Adult Population ◽

Amur Region ◽

Preschool Age ◽

First Year ◽

First Year Of Life

The aim of the research is to study the availability of vitamin D among children of different age and pregnant women living in the Amur region. 339 residents of Blagoveshchensk (279 children of different age and 60 adults) were examined. Among them there were 129 toddlers, 90 children of preschool age of 3-6 years old, 60 adolescents of 15-17 years old and 60 adults (pregnant women) of 18-40 years old. In the blood serum the content of the metabolite of vitamin D [25(OH)D] was studied by high performance liquid chromatography. The assessment of risk factors for failure and deficiency of vitamin D was conducted by clinical and anamnestic data. The first results of the study have been presented. They indicate a high frequency of various vitamin D deficiency in the population of the Amur region. Among 339 residents of the Amur region 92 (27.1%) had an adequate availability of vitamin D, 144 (42.4%) had an insufficiency of 25(OH)D; at the same time vitamin D deficiency was identified in 90 (26.5%) with 1/3 of the child population and 1/4 of pregnant women. The level of 25(OH)D within normal limits found in 37.5% of children in the first year of life decreased till 3.6 % by 3 years old, with its deficit increasing from 29.1% to 50%, persisting at this level (45.5 percent) in 3-6 year-old children, declining till 23.3% in adolescents and till 23.3% in pregnant women. The average vitamin D in the studied age periods was the highest in the first year of life (36.14±4.3 ng/ml), and the lowest in 2-3 year-old children (19.31±14.68 ng/ml), with a gradual increase in 3-6 years old (21.77±0.96 ng/ml); in 15-17 years old (23.89±0.66 ng/ml) and in pregnant women it has reached a level of 27.75±0.18 ng/ml, remaining below normal values. Respiratory infections, digestion, bone and joint systems pathologies are the most important risk factors contributing to the low status of 25 (OH) D; their prevention, alongside with the correction of vitamin D deficiency can improve the health of the population of the Amur region.

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Vitamin D Status and Its Associated Risk Factors among Adults in the Southwest Region of Cameroon

Journal of Nutrition and Metabolism ◽

10.1155/2018/4742574 ◽

2018 ◽

Vol 2018 ◽

pp. 1-9 ◽

Cited By ~ 2

Author(s):

Delphine A. Tangoh ◽

Tobias O. Apinjoh ◽

Yasir Mahmood ◽

Robert V. Nyingchu ◽

Beatrice A. Tangunyi ◽

...

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Hypovitaminosis D ◽

Vitamin D Status ◽

West Region ◽

South West ◽

Study Population ◽

Associated Risk Factors ◽

South West Region

Background. Vitamin D has been shown to exert its actions on the musculoskeletal, gastrointestinal, prostate, renal, endocrine, immune, and cardiovascular systems. Current reported data of hypovitaminosis D reveals a global pandemic, with an estimated one billion people worldwide presenting with hypovitaminosis D. Objective. This study aimed at investigating the vitamin D status and its associated risk factors in Cameroonians from the South West Region. Method. The study was a community- and hospital-based prospective longitudinal study. It was carried out during the dry and rainy seasons between the months of July and December 2015 in the South West Region of Cameroon involving 372 participants aged 35 years and above. After obtaining informed consent, a structured questionnaire was used to capture demographic data and risk factors of vitamin D deficiency. Blood samples were collected from the volunteer participants in the peak months of the rainy season and dry season, and the serum used to analyse for vitamin D by ELISA and calcium by spectrophotometry. 25(OH)D levels ≥75 nmol/L (≥30 ng/mL) were considered sufficient while levels <75 nmol/L were considered as hypovitaminosis D (insufficiency/deficiency). Results. Hypovitaminosis D (deficiency/insufficiency) was prevalent in 25.8% (96) of the study population, with only 3.2% (12) deficiency and 22.6% (84) insufficiency. There was a significant inverse relationship r=−0.119,p=0.02 between age and 25(OH)D levels; however, this relationship was not significant when controlled for gender, number of hours spent outdoors, and percentage of body covered. Gender, ethnic origin, percentage of body covered, time spent outdoors, and season did not influence serum vitamin D levels. Conclusion. Results of this study suggest that the prevalence of hypovitaminosis D is relatively low in this study population and only age is a risk factor of vitamin D deficiency.

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