scholarly journals Elevated resting heart rate is associated with increased radiographic severity of knee but not hand joints

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sung-Eun Choi ◽  
Haimuzi Xu ◽  
Ji-Hyoun Kang ◽  
Dong-Jin Park ◽  
Sun-Seog Kweon ◽  
...  
Keyword(s):  
Heart Rate ◽  
Knee Joint ◽  
Musculoskeletal Diseases ◽  
Smoking Status ◽  
Chronic Obstructive ◽  
Activity Levels ◽  
Resting Heart Rate ◽  
Radiographic Severity ◽  
Hand Joints ◽  
Risk Of Cancer

AbstractAlthough the resting heart rate (RHR) predicts the clinical outcomes of cardiovascular disease, chronic obstructive lung disease, diabetes mellitus, and the risk of cancer, its role in patients with musculoskeletal diseases, such as osteoarthritis (OA), remains unclear. We explored the association of the RHR with the extents of radiographic changes in the knees and hands of 2369 subjects from the Dong-gu Study. The radiographic hand and knee joint findings were graded semi-quantitatively; we calculated total hand and knee joint scores. Multiple linear regression was performed to examine the associations between the RHR and the radiographic characteristics of these joints. For the knee joints, the RHR was associated positively with the total (p < 0.01), osteophyte (p < 0.01), joint space narrowing (JSN; p < 0.01), and tibial attrition (p = 0.02) scores after adjustment for age, sex, body mass index, smoking status, alcohol consumption, educational and physical activity levels, and comorbidities. For the hand joints, the RHR was associated positively with the JSN (p = 0.01) and subchondral cyst (p < 0.01) scores after such adjustment. The RHR was not associated with the total, osteophyte, sclerosis, erosion, or malalignment score for the hand joints. This study is the first to reveal an association between the RHR and the radiographic severity of knee, but not hand, OA.

scholarly journals Resting Heart Rate as a Predictor of Cancer Mortality: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 10 (7) ◽  
pp. 1354
Author(s):  
Diana P. Pozuelo-Carrascosa ◽  
Iván Cavero-Redondo ◽  
I.M. Lee ◽  
Celia Álvarez-Bueno ◽  
Sara Reina-Gutierrez ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cancer Mortality ◽  
Meta Analysis ◽  
Positive Association ◽  
Cochrane Library ◽  
Resting Heart Rate ◽  
Potential Marker ◽  
Meta Analyses ◽  
Risk Of Cancer ◽  
The Relationship

This work was aimed to synthetize the evidence available about the relationship between resting heart rate (RHR) and the risk of cancer mortality. A computerized search in the Medline, EMBASE, Web of Science, and Cochrane Library databases from their inception to 24 September 2020 was performed. We performed three meta-analyses: (1) cancer mortality comparing the “less than 60 bpm” and “more than 60 bpm” categories; (2) cancer mortality comparing “less than 60 bpm”, “60 to 80 bpm”, and “more than 80 bpm” categories; and (3) analysis for 10–12 and 20 bpm increase in RHR and risk of cancer mortality. Twenty-two studies were included in the qualitative review, and twelve of them met the inclusion criteria for the meta-analysis. Our results showed a positive association between RHR and the risk of cancer mortality. This association was shown in a meta-analysis comparing studies reporting mean RHR values below and above 60 bpm, when comparing three RHR categories using less than 60 bpm as the reference category and, finally, in dose response analyses estimating the effect of an increase of 10–12 bpm in RHR, both in men and in women. In conclusion, a low RHR is a potential marker of low risk of cancer mortality.

scholarly journals Exercise Training in Patients with Chronic Respiratory Diseases: Are Cardiovascular Comorbidities and Outcomes Taken into Account?—A Systematic Review

2019 ◽  
Vol 8 (9) ◽  
pp. 1458 ◽  
Author(s):  
Ana Machado ◽  
Kirsten Quadflieg ◽  
Ana Oliveira ◽  
Charly Keytsman ◽  
Alda Marques ◽  
...  
Keyword(s):  
Systematic Review ◽  
Heart Rate ◽  
Exercise Training ◽  
Respiratory Diseases ◽  
Cardiovascular Outcomes ◽  
Chronic Obstructive ◽  
Resting Heart Rate ◽  
Cardiovascular Comorbidities ◽  
Exercise Programmes ◽  
The Impact

Patients with chronic obstructive pulmonary disease (COPD), asthma and interstitial lung diseases (ILD) frequently suffer from cardiovascular comorbidities (CVC). Exercise training is a cornerstone intervention for the management of these conditions, however recommendations on tailoring programmes to patients suffering from respiratory diseases and CVC are scarce. This systematic review aimed to identify the eligibility criteria used to select patients with COPD, asthma or ILD and CVC to exercise programmes; assess the impact of exercise on cardiovascular outcomes; and identify how exercise programmes were tailored to CVC. PubMed, Scopus, Web of Science and Cochrane were searched. Three reviewers extracted the data and two reviewers independently assessed the quality of studies with the Quality Assessment Tool for Quantitative Studies. MetaXL 5.3 was used to calculate the individual and pooled effect sizes (ES). Most studies (58.9%) excluded patients with both stable and unstable CVC. In total, 26/42 studies reported cardiovascular outcomes. Resting heart rate was the most reported outcome measure (n = 13) and a small statistically significant effect (ES = −0.23) of exercise training on resting heart rate of patients with COPD was found. No specific adjustments to exercise prescription were described. Few studies have included patients with CVC. There was a lack of tailoring of exercise programmes and limited effects were found. Future studies should explore the effect of tailored exercise programmes on relevant outcome measures in respiratory patients with CVC.

scholarly journals Exercise capacity and body mass index - important predictors of change in resting heart rate

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Michal Ehrenwald ◽  
Asaf Wasserman ◽  
Shani Shenhar-Tsarfaty ◽  
David Zeltser ◽  
Limor Friedensohn ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Heart Rate ◽  
Body Mass ◽  
Healthy Lifestyle ◽  
Smoking Status ◽  
Medical Center ◽  
Linear Regression Analysis ◽  
Density Lipoprotein ◽  
Resting Heart Rate ◽  
Metabolic Equivalents

Abstract Background Resting heart rate (RHR) is an obtainable, inexpensive, non-invasive test, readily available on any medical document. RHR has been established as a risk factor for cardiovascular morbidity, is related to other cardiovascular risk factors, and may possibly predict them. Change in RHR over time (∆RHR) has been found to be a potential predictor of mortality. Methods In this prospective study, RHR and ∆RHR were evaluated at baseline and over a period of 2.9 years during routine check-ups in 6683 subjects without known cardiovascular disease from the TAMCIS: Tel-Aviv Medical Center Inflammation Survey. Multiple linear regression analysis with three models was used to examine ∆RHR. The first model accounted for possible confounders by adjusting for age, sex and body mass index (BMI). The 2nd model included smoking status, baseline RHR, diastolic blood pressure (BP), dyslipidemia, high-density lipoprotein (HDL) and metabolic equivalents of task (MET), and in the last model the change in MET and change in BMI were added. Results RHR decreased with age, even after adjustment for sex, BMI and MET. The mean change in RHR was − 1.1 beats/min between two consecutive visits, in both men and women. This ∆RHR was strongly correlated with baseline RHR, age, initial MET, and change occurring in MET and BMI (P < 0.001). Conclusions Our results highlight the need for examining individual patients’ ∆RHR. Reinforcing that a positive ∆RHR is an indicator of poor adherence to a healthy lifestyle.

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