scholarly journals Compounds from Caesalpinia sappan with anti-inflammatory properties in macrophages and chondrocytes

2016 ◽  
Vol 7 (3) ◽  
pp. 1671-1679 ◽  
Author(s):  
Monika Mueller ◽  
Daniela Weinmann ◽  
Stefan Toegel ◽  
Wolfgang Holzer ◽  
Frank M. Unger ◽  
...  

The heartwood of Caesalpinia sappan is a traditional ingredient of food and beverages in South East Asia and has been used in traditional medicine as an analgesic and anti-inflammatory drug or to promote blood circulation.

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Gilhye Lee ◽  
Jung-Hee Kim ◽  
Hyun-Jae Jang ◽  
Ji-Won Park ◽  
Jae-Won Lee ◽  
...  

Pyrus pyrifolia Nakai (P. pyrifolia) has been traditionally used in East Asia to treat diseases such as phlegm, cough, hangover, and fever. However, there is no investigation that evaluates the biological activities of the leaves of P. pyrifolia. This study aims at describing the anti-inflammatory effects of PP, a bioactive fraction from the leaves of P. pyrifolia, in lipopolysaccharide (LPS)-stimulated THP-1 cells. Initially, PP decreased the protein and RNA expression of TNF-α, MCP-1, IL-8, and IL-6 induced by LPS. Moreover, PP attenuated the phosphorylation of p38, JNK, and ERK. In addition, after stimulation with LPS, the degradation of IκB-α was suppressed by PP, and the phosphorylation of IκB-α and p65 was suppressed by PP. Additionally, PP increased HO-1, which controls the production of inflammatory molecules, by activating Nrf2. These results indicated that PP could be used as an anti-inflammatory drug to promote wellness.


2021 ◽  
Author(s):  
Sultana Parven ◽  
Aparajita De ◽  
Abhik Gupta

Abstract Enydra fluctuans DC. (Asteraceae) is an edible semi-aquatic floating or trailing herbaceous plant widely distributed in tropical Africa, South and South East Asia, and Australia. Its leaves, which are consumed as a vegetable, are also used in traditional medicine to treat several diseases. The efficacy of this plant in removal of copper and lead from aqueous medium was tested in the present study. Accumulation of both Cu and Pb was significantly higher in root than that in leaf and stem. Though all the bioconcentration factor (BCF) values were greater than unity, none of the translocation factor (TF) values was greater than unity, indicating that this plant could not be considered a hyperaccumulator of these metals. Nevertheless, E. fluctuans could remove Cu from aqueous medium at rates ranging from 98.8–99.7 %, with a mean reduction of 99.2 % after 96 h exposure at various concentrations. The removal of Pb ranged from 97.1–99.1 %, with a mean reduction of 98.2 %. Thus, E. fluctuans showed high potential in removal of Cu and Pb from aqueous medium, and has the prospect of being used in phytoremediation of these metals.


2018 ◽  
Vol 3 (3) ◽  

To determine the immunization status of pediatric patients under age of 5 years visiting pediatric department of tertiary care hospitals in South East Asia. The aim of this study was to appreciate the awareness and implementation of vaccination in pediatric patients who came into pediatric outpatient Department with presenting complain other than routine vaccination. we can also know the count of patients who do not complete their vaccination after birth. we can differentiate between vaccinated and unvaccinated patients and incidence of severe disease in both groups. Immunization is a protective process which makes a person resistant to the harmful diseases prevailing in the community, typically by vaccine administration either orally or intravenously. It is proven for controlling and eliminating many threatening diseases from the community. WHO report that licensed vaccines are available for the prevention of many infectious diseases. After the implementation of effective immunization the rate of many infectious diseases have declined in many countries of the world. South-East Asia is far behind in the immunization coverage. An estimated total coverage is 56%-88% for a fully immunized child, which is variable between countries. Also the coverage is highest for BCG and lowest for Polio.


2014 ◽  
Vol 41 (2) ◽  
pp. 230-239 ◽  
Author(s):  
Charles E. Jarvis ◽  
Joanne H. Cooper

It had long been believed that none of the bird, egg or nest specimens that had been in the collection of Sir Hans Sloane at his death in 1753 had survived. However, a specimen of a rhinoceros hornbill, originally in Sloane's hands, was discovered in the Natural History Museum's collections in London in 2003, and three more Sloane hornbill specimens have subsequently come to light. In addition, we report here a most unexpected discovery, that of the head of a woodpecker among the pages of one of Sloane's bound volumes of pressed plants. The context suggests that the head, like its associated plant specimens, was probably collected in south-east Asia about 1698–1699 by Nathanael Maidstone, an East India Company trader, the material reaching Sloane via William Courten after the latter's death in 1702. A detailed description of the head is provided, along with observations on its identity and possible provenance.


Writing from a wide range of historical perspectives, contributors to the anthology shed new light on historical, theoretical and empirical issues pertaining to the documentary film, in order to better comprehend the significant transformations of the form in colonial, late colonial and immediate post-colonial and postcolonial times in South and South-East Asia. In doing so, this anthology addresses an important gap in the global understanding of documentary discourses, practices, uses and styles. Based upon in-depth essays written by international authorities in the field and cutting-edge doctoral projects, this anthology is the first to encompass different periods, national contexts, subject matter and style in order to address important and also relatively little-known issues in colonial documentary film in the South and South-East Asian regions. This anthology is divided into three main thematic sections, each of which crosses national or geographical boundaries. The first section addresses issues of colonialism, late colonialism and independence. The second section looks at the use of the documentary film by missionaries and Christian evangelists, whilst the third explores the relation between documentary film, nationalism and representation.


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