Direct cellular organization with ring-shaped composite polymers and glass substrates for urethral sphincter tissue engineering

2016 ◽  
Vol 4 (22) ◽  
pp. 3998-4008 ◽  
Author(s):  
Wenqiang Du ◽  
Jianfeng Chen ◽  
Huan Li ◽  
Gang Zhao ◽  
Guangli Liu ◽  
...  

We introduce the substrates of composite materials for sphincter tissue engineering and demonstrate the mechanisms of how dimensions, curvature and parallelism of constraints affect cellular organization.

Materials ◽  
2019 ◽  
Vol 12 (11) ◽  
pp. 1874 ◽  
Author(s):  
Natalia V. Smirnova ◽  
Konstantin A. Kolbe ◽  
Elena N. Dresvyanina ◽  
Sergey F. Grebennikov ◽  
Irina P. Dobrovolskaya ◽  
...  

This paper discusses the mechanical and physicochemical properties of film matrices based on chitosan, as well as the possibility of optimizing these properties by adding chitin nanofibrils. It is shown that with the introduction of chitin nanofibrils as a filler, the mechanical stability of the composite materials increases. By varying the concentration of chitin nanofibrils, it is possible to obtain a spectrum of samples with different bioactive properties for the growth of human dermal fibroblasts. Film matrices based on the nanocomposite of chitosan and 5 wt % chitin nanofibrils have an optimal balance of mechanical and physicochemical properties and bioactivity in relation to the culture of human dermal fibroblasts.


2009 ◽  
Vol 190 (1-2) ◽  
pp. 89-94 ◽  
Author(s):  
Nadine Le Bolay ◽  
Véronique Santran ◽  
Gérard Dechambre ◽  
Christèle Combes ◽  
Christophe Drouet ◽  
...  

2021 ◽  
Vol 63 (2) ◽  
pp. 219-226
Author(s):  
T. S. Demina ◽  
T. A. Akopova ◽  
A. N. Zelenetsky

Abstract The transition to green chemistry and biodegradable polymers is a logical stage in the development of modern chemical science and technology. In the framework of this review, the advantages, disadvantages, and potential of biodegradable polymers of synthetic and natural origin are compared using the example of polylactide and chitosan as traditional representatives of these classes of polymers, and the possibilities of their combination via obtaining composite materials or copolymers are assessed. The mechanochemical approach to the synthesis of graft copolymers of chitosan with oligolactides/polylactides is considered in more detail.


2019 ◽  
Vol 14 (12) ◽  
pp. 1900055 ◽  
Author(s):  
Ekaterina Naumenko ◽  
Rawil Fakhrullin

2011 ◽  
Vol 2 (1) ◽  
pp. 85-90 ◽  
Author(s):  
A. Yu. Fedotov ◽  
V. S. Komlev ◽  
V. V. Smirnov ◽  
I. V. Fadeeva ◽  
S. M. Barinov ◽  
...  

Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 965
Author(s):  
Zuzana Weberová ◽  
Hana Šourková ◽  
Jakub Antoň ◽  
Taťána Vacková ◽  
Petr Špatenka

This paper describes a newly developed testing method for determination of the adhesivity of a film sintered from thermoplastic powder. This method is based on the modified EN 15337 standard. Application of this method enables an effective development of thermoplastic composites with enhanced adhesion between reinforcement and matrix and/or high-quality joints between plastics and dissimilar materials. The proposed method was successfully tested on a series of polyethylene powders treated in the oxygen atmosphere for 0–1200 s. Adhesion to metal and glass substrates in dependence on treatment conditions is described along with powder wettability and X-ray photoelectron spectroscopy analysis. The results show an increase in adhesion to metal by 580% and to glass by 1670% for the longest treatment time, compared to a nontreated powder. Sintering of treated powders revealed a strong influence of treatment time on the melting process. The XPS analysis confirmed the formation of new oxygen groups (C–O, C=O, O–C=O). The method reveals a specific behavior of powders based on treatment conditions, which is crucial for the optimization of plasma treatment for the improved adhesion, applicability of polymer powders, and a development of composite materials.


2021 ◽  
Vol 2 (1) ◽  
pp. 154-167
Author(s):  
Vasilina A. Zakharova ◽  
Nataliya R. Kildeeva

For the creation of tissue-engineered structures based on natural biopolymers with the necessary chemical, physical, adhesive, morphological, and regenerative properties, biocompatible materials based on polysaccharides and proteins are used. This work is devoted to a problem of the technology of polymeric materials for biomedical purposes: the creation of biopolymer tissue engineering matrix and the development of a methodology for studying morphology and functional properties of their surface to establish the prospects for using the material for contact with living objects. The conditions for the formation of scaffolds based on composite materials of chitosan and fibroin determine the structure of the material, the thickness and orientation of molecular layers, the surface morphology, and other parameters that affect cell adhesion and growth. The analysis of studies of the morphology and properties of the surface of biopolymer matrices obtained using different methods of molding from solutions of chitosan and fibroin is carried out.


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