Title- Role of herbal products in curing Vitiligo

Plants produce a wide diversity of secondary metabolites which serve them as defence compounds against herbivores, and other plants and microbes, but also as signal compounds. In general, secondary metabolites exhibit a wide array of biological and pharmacological properties. Because of this, some plants or products isolated from them have been and are still used to treat infections, health disorders or diseases. Vitiligo is a skin disorder that is caused due to oxidative stress in the body resulting in the destruction of melanocytes, which are the cells responsible for the pigmentation of the skin. On their destruction the skin gets depigmented resulting in patches of skin losing their colour. In this review we focus on how plant based herbal products help in curing vitiligo.

Environmental Toxicant and Immune cells: A Review

Immune system is the adaptive defense mechanism which is evolved in vertebrates to keep them from invading pathogenic microorganisms and cancer. In immune system consists of some specialized cells like: lymphocytes, neutrophils, NK cells, basophils, macrophages, eiosinophils, mast cells, etc.Ecotoxicology is a subdisicipline of environmental toxicology concerd with studing the damaging effects of toxicants at the population and nature. Environmental toxicants are simply toxic substances in the nature. Environmental toxicant which is effect on ecosystem very badly.In this paper we discuss that how environmental toxicant effect on immune system or immune cells.

Determination & expression of chimeric protein in colorectal cancer: A bioinformatics Approach

Colorectal cancer (CRC) accounts for about 10% of cancer-related mortality in western countries. Increasing ageing population, undesirable modern dietary and high-risk factors like smoking, obesity and low exercise. Chromosomal instability (CIN), CpG island methylator phenotype (CIMP), and microsatellite instability are the three different mechanism that give rise to CRC. It often grow slowly, and customarily doesn’t produce symptoms until reaching a substantial size of several centimeters, which can block the passage of feces and cause cramping, pain, or bleeding which can present as visible bleeding with bowel movements or, rarely, dark “tarry” stools. Most colon tumors develop via a several different processes involving a series of histological, morphological, and genetical changes that accumulate over time to time. New treatments for primary and metastatic colorectal cancer have emerged, like in variety of therapeutic process by preparing chimeric proteins that triggers the cells and stop it from getting severe.

Synthesis and Characterization of a Biocompatible Bioactive Borate Glass

A typical bioactive borate glass of composition 5Na2O-30Ca-65B2O3(NCBO) was prepared by melt quenching method. The NCBO glass powder and solid glass fibers were found to slowly converted to nanocrystalline hydroxyapatite (or Ca10(PO4)6(OH)2) by soaking in (0.25M)K2HPO4(KDP) solution (with pH = 9.5 and Ca/P ratio ˜1.6 at 37°C) for about one month. We studied biocompatibility (cells adhesion and proliferation) of the NCBO glass by allowing adhesion and proliferation of human cord blood derived mesenchymal stem cells (CB-hMSCs) directly on the thin glass plate. The cells viability on glass surface was determined by MTT [3-(4,5-di-methylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide] assay analysis. The NCBO glass exhibiting excellent biocompatibility might be suitable for in vivo tissue engineering applications.

Identification of Plant Diseases: A short review

As per FAO (2000) reports, 67% of population are involved in Agriculture, and alone contributing to 34% of overall GDP. Diseases in Plants cases major losses therefore it’s quite evident that proper monitoring and disease detection is necessary for sustainability. According to several reports, in the period 2001-2003, Global potential loss varied to about 29% in soyabean, 50% in wheat to about 80% in Cotton. This short synopsis will be acting a small referral piece of document to give an idea about the common Fungal, Viral, Bacterial diseases. This shall also be discussing about some of the conventional techniques for disease detection in plants viz.; Microarray, PCR, ELISA etc.

Arsenic Pollution: An Insight into its Effect in Plant Productivity and Human Health

Arsenic (As), a naturally occurring metalloid, has been a major concern to the environment due to its adverse effects on the plants and human. Arsenic uptake and accumulation in plants has not only impaired the plant processes leading to loss in growth and crop yield but also resulted in toxicity in human due to biomagnification. With decades of research on the effects of arsenic accumulation on plant growth and development and its consequences in human health, we briefly discuss the effects of As on plants and humans. In the first part of the review the principles of uptake of As by plant from soil are discussed. In the second part, the primary mechanism through which the As accumulation affect plant productivity are discussed. The last part describes the effect As has on different human organs. Our mini-review serves to guide the ongoing and future research on the effects As contamination.