Let food be your medicine: nutraceutical properties of lycopene

2019 ◽  
Vol 10 (6) ◽  
pp. 3090-3102 ◽  
Author(s):  
Małgorzata Grabowska ◽  
Dariusz Wawrzyniak ◽  
Katarzyna Rolle ◽  
Piotr Chomczyński ◽  
Stefan Oziewicz ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Human Health ◽  
Nutraceutical Properties

In this review, we highlight research and clinical trials involving lycopene and its impact on human health.

scholarly journals Modulation of Gut Microbiota for the Prevention and Treatment of COVID-19

2021 ◽  
Vol 10 (13) ◽  
pp. 2903
Author(s):  
Jiezhong Chen ◽  
Luis Vitetta
Keyword(s):  
Clinical Trials ◽  
Trace Elements ◽  
Gut Microbiota ◽  
Human Health ◽  
Intestinal Microbiota ◽  
Narrative Review ◽  
Bacterial Metabolites ◽  
Gut Dysbiosis ◽  
Prevention And Treatment

The gut microbiota is well known to exert multiple benefits on human health including protection from disease causing pathobiont microbes. It has been recognized that healthy intestinal microbiota is of great importance in the pathogenesis of COVID-19. Gut dysbiosis caused by various reasons is associated with severe COVID-19. Therefore, the modulation of gut microbiota and supplementation of commensal bacterial metabolites could reduce the severity of COVID-19. Many approaches have been studied to improve gut microbiota in COVID-19 including probiotics, bacterial metabolites, and prebiotics, as well as nutraceuticals and trace elements. So far, 19 clinical trials for testing the efficacy of probiotics and synbiotics in COVID-19 prevention and treatment are ongoing. In this narrative review, we summarize the effects of various approaches on the prevention and treatment of COVID-19 and discuss associated mechanisms.

scholarly journals Bioaccessibility of Marine Carotenoids

Marine Drugs ◽  
2018 ◽  
Vol 16 (10) ◽  
pp. 397 ◽  
Author(s):  
Isabel Viera ◽  
Antonio Pérez-Gálvez ◽  
María Roca
Keyword(s):  
Pharmaceutical Industry ◽  
Human Health ◽  
Industrial Production ◽  
Food Industry ◽  
Industrial Applications ◽  
Point Of View ◽  
Market Area ◽  
Biological Functions ◽  
Determination Methods ◽  
Nutraceutical Properties

The benefit of carotenoids to human health is undeniable and consequently, their use for this purpose is growing rapidly. Additionally, the nutraceutical properties of carotenoids have attracted attention of the food industry, especially in a new market area, the ‘cosmeceuticals.’ Marine organisms (microalgae, seaweeds, animals, etc.) are a rich source of carotenoids, with optimal properties for industrial production and biotechnological manipulation. Consequently, several papers have reviewed the analysis, characterization, extraction and determination methods, biological functions and industrial applications. But, now, the bioaccessibility and bioactivity of marine carotenoids has not been focused of any review, although important achievements have been published. The specific and diverse characteristic of the marine matrix determines the bioavailability of carotenoids, some of them unique in the nature. Considering the importance of the bioavailability not just from the health and nutritional point of view but also to the food and pharmaceutical industry, we consider that the present review responds to an actual demand.

scholarly journals A Systematic Review of Organic Versus Conventional Food Consumption: Is There a Measurable Benefit on Human Health?

Nutrients ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 7 ◽  
Author(s):  
Vigar ◽  
Myers ◽  
Oliver ◽  
Arellano ◽  
Robinson ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Health Outcomes ◽  
Human Health ◽  
Food Consumption ◽  
Health Benefits ◽  
Organic Food ◽  
Observational Research ◽  
Current Evidence ◽  
Current Evidence Base ◽  
Organic Food Consumption

The current review aims to systematically assess the evidence related to human health outcomes when an organic diet is consumed in comparison to its conventional counterpart. Relevant databases were searched for articles published to January 2019. Clinical trials and observational research studies were included where they provided comparative results on direct or indirect health outcomes. Thirty-five papers met the criteria for inclusion in the review. Few clinical trials assessed direct improvements in health outcomes associated with organic food consumption; most assessed either differences in pesticide exposure or other indirect measures. Significant positive outcomes were seen in longitudinal studies where increased organic intake was associated with reduced incidence of infertility, birth defects, allergic sensitisation, otitis media, pre-eclampsia, metabolic syndrome, high BMI, and non-Hodgkin lymphoma. The current evidence base does not allow a definitive statement on the health benefits of organic dietary intake. However, a growing number of important findings are being reported from observational research linking demonstrable health benefits with organic food consumption. Future clinical research should focus on using long-term whole-diet substitution with certified organic interventions as this approach is more likely to determine whether or not true measurable health benefits exist.

scholarly journals Nutraceuticals in Human Health

Foods ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 370 ◽  
Author(s):  
Alessandra Durazzo ◽  
Massimo Lucarini ◽  
Antonello Santini
Keyword(s):  
Clinical Trials ◽  
Health Status ◽  
Human Health ◽  
Biologically Active ◽  
Bioactive Components ◽  
Special Issue ◽  
Concerted Action ◽  
Beneficial Effects ◽  
Wide Range ◽  
Efficacy Studies

The combined and concerted action of nutrient and biologically active compounds is flagged as an indicator of a “possible beneficial role” for health. The use and applications of bioactive components cover a wide range of fields, in particular the nutraceuticals. In this context, the Special Issue entitled “Nutraceuticals in Human Health” is focused on the all aspects around the nutraceuticals, ranging from analytical aspects to clinical trials, from efficacy studies to beneficial effects on health status.

scholarly journals A Brief Overview on Probiotics: The Health Friendly Microbes

2021 ◽  
Vol 14 (4) ◽  
pp. 1869-1880
Author(s):  
Sanjukta Mishra ◽  
Swastik Acharya
Keyword(s):  
Clinical Trials ◽  
Human Health ◽  
Intrinsic Property ◽  
Saccharomyces Boulardii ◽  
Human Beings ◽  
Fatty Acid Production ◽  
Beneficial Effects ◽  
Probiotic Mechanisms

Probiotics are defined as non-pathogenic live microorganisms that, when administered in adequate amounts, confer health benefits on the host. Association of probiotics with human beings has a lot of history. Well known as 'health-friendly bacteria', they are widely used commercially as a functional food. The popularity of probiotics has gone exponentially high due to an increasing number of clinical trials, supporting their beneficial effects. Several in vivo and in-vitro experimental evidence supports strain-specific and disease-specific probiotic efficacy to prevent and ameliorate antibiotic-associated diarrhoea, traveller's diarrhoea, ulcerative colitis, and many more. Besides, numerous recent studies have reported that probiotics could have a significant effect in alleviating various metabolic, lifestyle and diet-related disorders like obesity, type 2 diabetes, metabolic syndrome, irritable bowel syndrome Strains of Bifidobacterium, Lactobacillus and Saccharomyces boulardii are the most commonly used as probiotics. Safety, efficacy, pathogenicity, infectivity, intrinsic property, virulence factors are to be addressed during probiotic selection. The underlying mechanisms of probiotics effects are still not fully elucidated and have been under intensive research. Numerous diverse, strain-specific probiotic mechanisms have been proposed, which include early colonization of perturbed microbes, competitive exclusion of pathogens, short-chain volatile fatty acid production, alteration of gut pH, immunomodulation and many more. Considering the remarkable influence on human health, probiotics seem to be alluring attractive agents to promote human health conditions and to improve the quality of life against several diseases. This review discusses the current documentation and recent advances on probiotics and their possible health attributes, in scientific literature, focusing on diverse, heterogeneous, and strain-specific mechanisms of action. Randomised human controlled clinical trials are needed to reconfirm its safety and beneficial effects.

scholarly journals Probiotics: Past, Present and Future Challenges

10.3823/816 ◽  
2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Baraa M. AL-Taha ◽  
Jamal Wadi ◽  
Asem A. Shehabi
Keyword(s):  
Clinical Trials ◽  
Human Health ◽  
Large Bowel ◽  
Bacterial Species ◽  
Nutritional Supplement ◽  
Review Article ◽  
Research Topic ◽  
Gut Flora ◽  
Future Challenges ◽  
The Status

The term probiotic (prolife) is utilized to describe useful living microorganisms, intended to colonize the large bowel, when consumed in adequate amounts, they confer physiological health benefits to the host. In the last decade, probiotics have been widely used as a nutritional supplement and became a rapidly developing research topic that gained importance in medicine. Recent clinical trials have found that consumption of beneficial bacterial species can manipulate gut flora and reduce or prevent the development of certain serious diseases. This brief review article is intended to discuss the status of research on probiotics, and the value of their consumption in human health.

scholarly journals Nutraceutical Properties of Legume Seeds and Their Impact on Human Health

2019 ◽  
Author(s):  
Arindam Barman ◽  
Chinky M. Marak ◽  
Rituparna Mitra Barman ◽  
Cheana S. Sangma
Keyword(s):  
Human Health ◽  
Legume Seeds ◽  
Nutraceutical Properties

Phytotherapic Drugs For Covid19 Treatment: A Scoping Review

2021 ◽  
Vol 27 ◽  
Author(s):  
Meenakshi Singh ◽  
Darshini Trivedi ◽  
Reecha Mohapatra ◽  
Trisha Bagchi ◽  
Chandra Sai Potla Durthi ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Side Effects ◽  
Antiviral Activity ◽  
Human Health ◽  
Bioactive Compounds ◽  
Well Being ◽  
Bioactive Metabolites ◽  
Herbal Extracts ◽  
Plant Metabolites ◽  
Health Crisis

Background: The rapid eruption of Coronavirus at the end of 2019 has caused global health crisis and significant loss to the economy and social well-being. This created a massive shortage of advanced health facilities with inadequate medicinal supply, further deteriorating human health conditions. On the basis of adverse effects of the ongoing pandemic, this review is proposed to evaluate the antiviral efficacy of plant-based therapeutics against SARS-CoV-2 (commonly called COVID19) infection. It highlights the possible action of the mechanism of phytotherapeutic drugs against coronavirus inhibition, further validated by clinical trials on herbal formulas. Though the experimental studies on COVID19 treatment are limited, the undesirable side effects of herbal drugs and unidentified compounds cannot be ignored. Objective: We have made an effort to study the prospective plant-derived bioactive entities and their effectiveness in the treatment of COVID19 and emphasize safety and regulatory concerns of phytomedicines. Methods: The methodology involves the relevant studies on COVID19 treatment based on herbal extracts and the purified bioactive metabolites. The e-literature survey is done by downloading research articles available on PubMed (National library of medicine), Elsevier, and Google scholar search engines. The keywords used are plant metabolites, natural bioactive, phytotherapeutic drugs, clinical trials, SARS-CoV-2, Coronavirus inhibitors and herbal extracts. Results: The review pays particular attention to the etiological study of the COVID19 virus and its inhibition using medicinal plant metabolites as immunomodulatory agents. The application of valuable bioactive like phenolic compounds, saponins, alkaloids, tannins, flavonoids and terpenoids in preparing herbal formula/drug. The drug resistance of bioactive compounds and their side effects on human health were discussed for effective phytomedicine. Thus, emphasizing the perspectives of phytotherapeutic drugs as a safe remedy to boost immunomodulatory functions and antiviral activity against COVID19. Conclusion: Altogether, the review presents the action mechanism of plant extracts rich in bioactive compounds and depicted potential antiviral activity against SARS-CoV-2. These plant bioactive compounds can serve as lead molecules to develop phytomedicine, ensuring all safety regulations in the clinical trials to treat or prevent COVID19 viral infections.

scholarly journals Edible Mushrooms: Improving Human Health and Promoting Quality Life

2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
María Elena Valverde ◽  
Talía Hernández-Pérez ◽  
Octavio Paredes-López
Keyword(s):  
Vitamin D ◽  
Immune System ◽  
Human Health ◽  
Chinese Culture ◽  
Food Source ◽  
Health Food ◽  
Invasion And Metastasis ◽  
Beneficial Effects ◽  
Quality Life ◽  
Nutraceutical Properties

Mushrooms have been consumed since earliest history; ancient Greeks believed that mushrooms provided strength for warriors in battle, and the Romans perceived them as the “Food of the Gods.” For centuries, the Chinese culture has treasured mushrooms as a health food, an “elixir of life.” They have been part of the human culture for thousands of years and have considerable interest in the most important civilizations in history because of their sensory characteristics; they have been recognized for their attractive culinary attributes. Nowadays, mushrooms are popular valuable foods because they are low in calories, carbohydrates, fat, and sodium: also, they are cholesterol-free. Besides, mushrooms provide important nutrients, including selenium, potassium, riboflavin, niacin, vitamin D, proteins, and fiber. All together with a long history as food source, mushrooms are important for their healing capacities and properties in traditional medicine. It has reported beneficial effects for health and treatment of some diseases. Many nutraceutical properties are described in mushrooms, such as prevention or treatment of Parkinson, Alzheimer, hypertension, and high risk of stroke. They are also utilized to reduce the likelihood of cancer invasion and metastasis due to antitumoral attributes. Mushrooms act as antibacterial, immune system enhancer and cholesterol lowering agents; additionally, they are important sources of bioactive compounds. As a result of these properties, some mushroom extracts are used to promote human health and are found as dietary supplements.

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