A turn-on fluorescent sensor based on carbon dots from Sophora japonica leaves for the detection of glyphosate

2020 ◽  
Vol 12 (33) ◽  
pp. 4130-4138
Author(s):  
Jingzhou Hou ◽  
Xianfeng Wang ◽  
Shiyu Lan ◽  
Chao Zhang ◽  
Changjun Hou ◽  
...  

Carbon dots (CDs) having low cost and low toxicity and synthesized via a green route were applied to establish a fluorescent nanoprobe for the measurement of glyphosate.


Author(s):  
Junzhe Chen ◽  
Haiying Du ◽  
Yifeng Xu ◽  
Boyu Ma ◽  
Zhihong Zheng ◽  
...  


Polymers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 4317
Author(s):  
Xinxin Wang ◽  
Yanan Zhao ◽  
Ting Wang ◽  
Yan Liang ◽  
Xiangzhong Zhao ◽  
...  

As lactoferrin (LF) plays an essential role in physiological processes, the detection of LF has attracted increasing attention in the field of disease diagnosis. However, most current methods require expensive equipment, laborious pretreatment, and long processing time. In this work, carboxyl-rich carbon dots (COOH-CDs) were facilely prepared through a one-step, low-cost hydrothermal process with tartaric acid as the precursor. The COOH-CDs had abundant carboxyl on the surface and showed strong blue emission. Moreover, COOH-CDs were used as a fluorescent sensor toward Fe3+ and showed high selectivity for Fe3+ with the limit of detection (LoD) of 3.18 nM. Density functional theory (DFT) calculations were performed to reveal the mechanism of excellent performance for Fe3+ detection. Meanwhile, COOH-CDs showed no obvious effect on lactobacillus plantarum growth, which means that COOH-CDs have good biocompatibility. Due to the nontoxicity and excellent detection performance for Fe3+, COOH-CDs were employed as a fluorescent sensor toward LF and showed satisfying performance with an LoD of 0.776 µg/mL, which was better than those of the other methods.



2017 ◽  
Vol 9 (26) ◽  
pp. 3941-3948 ◽  
Author(s):  
Xu-Cheng Fu ◽  
Jiang-Zhou Jin ◽  
Ju Wu ◽  
Jun-Cheng Jin ◽  
Cheng-Gen Xie

Photoluminescent C-dots made by a one-step electrolysis method make a selective fluorescent sensor for Al3+ over other metal ions.



Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1981
Author(s):  
Roberto Sotolongo-García ◽  
Eustolia Rodríguez-Velázquez ◽  
Manuel Alatorre-Meda ◽  
Mercedes T. Oropeza-Guzmán ◽  
Antonio Tirado-Guízar ◽  
...  

In this work, the Förster resonance energy transfer (FRET) between carbon dots (CDs) as energy donors and riboflavin (RF) as an energy acceptor was optimized and the main parameters that characterize the FRET process were determined. The results were successfully applied in the development of an ultrasensitive ratiometric fluorescent sensor for the selective and sensitive determination of RF in different beverages. Water-soluble CDs with a high quantum yield (54%) were synthesized by a facile and direct microwave-assisted technique. The CDs were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), Zeta potential, and UV-visible and molecular fluorescence spectroscopy. The study of the FRET process at two donor concentrations showed that the energy transfer efficiency decreases as the donor concentration increases, confirming its dependence on the acceptor:donor ratio in nanoparticle-based systems. The results show the importance of optimizing the FRET process conditions to improve the corresponding output signal. The variation in the ratiometric signal with the concentration of RF showed linearity in a concentration range of 0 to 11 µM with R2 = 0.9973 and a detection limit of 0.025 µM. The developed nanosensor showed good selectivity over other possible types of interference. The sensor was then applied for the determination of RF in beverage samples using the standard addition method with recoveries between 96% and 106%. Preliminary cytocompatibility tests carried out with breast cancer cells (MDA-MB-231) revealed the nanosensor to be cytocompatible in its working concentration regime, even after long incubation times with cells. Altogether, the developed RF determination method was found to be fast, low-cost, highly sensitive, and selective and can be extended to other samples of interest in the biological and food sectors. Moreover, thanks to its long-lasting cytocompatibility, the developed platform can also be envisaged for other applications of biological interest, such as intracellular sensing and staining for live cell microscopy.



2019 ◽  
Vol 280 ◽  
pp. 290-297 ◽  
Author(s):  
Vanesa Romero ◽  
Victoria Vila ◽  
Inmaculada de la Calle ◽  
Isela Lavilla ◽  
Carlos Bendicho


Nanomaterials ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 634 ◽  
Author(s):  
Susana Campuzano ◽  
Paloma Yáñez-Sedeño ◽  
José M. Pingarrón

Graphene quantum dots (GQDs) and carbon dots (CDs) are among the latest research frontiers in carbon-based nanomaterials. They provide interesting attributes to current electrochemical biosensing due to their intrinsic low toxicity, high solubility in many solvents, excellent electronic properties, robust chemical inertness, large specific surface area, abundant edge sites for functionalization, great biocompatibility, low cost, and versatility, as well as their ability for modification with attractive surface chemistries and other modifiers/nanomaterials. In this review article, the use of GQDs and CDs as signal tags or electrode surface modifiers to develop electrochemical biosensing strategies is critically discussed through the consideration of representative approaches reported in the last five years. The advantages and disadvantages arising from the use of GQDs and CDs in this context are outlined together with the still required work to fulfil the characteristics needed to achieve suitable electrochemical enzymatic and affinity biosensors with applications in the real world.



Nanoscale ◽  
2021 ◽  
Author(s):  
Yiqun Ni ◽  
Xiangyang Li ◽  
Wenqing Liang ◽  
Shaofeng Zhang ◽  
Xuesong Xu ◽  
...  

Carbon dots (CDs), a subject of academic research, have attracted intense attention due to their intrinsic merits of high stability, low cost, and low toxicity. However, the absence of highly...



2020 ◽  
Vol 25 (46) ◽  
pp. 4848-4860 ◽  
Author(s):  
Anisha Anand ◽  
Gopinathan Manavalan ◽  
Ranju Prasad Mandal ◽  
Huan-Tsung Chang ◽  
Yi-Ru Chiou ◽  
...  

: The prevention and treatment of various infections caused by microbes through antibiotics are becoming less effective due to antimicrobial resistance. Researches are focused on antimicrobial nanomaterials to inhibit bacterial growth and destroy the cells, to replace conventional antibiotics. Recently, carbon dots (C-Dots) become attractive candidates for a wide range of applications, including the detection and treatment of pathogens. In addition to low toxicity, ease of synthesis and functionalization, and high biocompatibility, C-Dots show excellent optical properties such as multi-emission, high brightness, and photostability. C-Dots have shown great potential in various fields, such as biosensing, nanomedicine, photo-catalysis, and bioimaging. This review focuses on the origin and synthesis of various C-Dots with special emphasis on bacterial detection, the antibacterial effect of CDots, and their mechanism.



2020 ◽  
Vol 21 (9) ◽  
pp. 661-673 ◽  
Author(s):  
Mohammed Asadullah Jahangir ◽  
Chettupalli Anand ◽  
Abdul Muheem ◽  
Sadaf Jamal Gilani ◽  
Mohamad Taleuzzaman ◽  
...  

Herbal medicines are being used since ancient times and are an important part of the alternative and traditional medicinal system. In recent decades, scientists are embracing herbal medicines based on the fact that a number of drugs that are currently in use are derived directly or indirectly from plant sources. Moreover, herbal drugs have lesser side effects, albeit are potentially strong therapeutic agents. The herbal medicine market is estimated to be around US $62 billion globally. Herbal medicine has gained widespread acceptance due to its low toxicity, low cost, ease of accessibility and efficacy in treating difficult diseases. Safety and efficacy are another important factors in the commercialization process of herbal medicines. Nanotechnology has been shown to be potentially effective in improving the bioactivity and bioavailability of herbal medicines. Development of nano-phytomedicines (or by reducing the size of phytomedicine), attaching polymers with phytomedicines and modifying the surface properties of herbal drugs, have increased the solubility, permeability and eventually the bioavailability of herbal formulations. Novel formulations such as niosomes, liposomes, nanospheres, phytosomes etc., can be exploited in this area. This article reviews herbal medicines, which have prominent activity in the Central Nervous System (CNS) disorders and reported nano-phytomedicines based delivery systems.



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