Coagulation of organic pollutants by Moringa oleifera protein molecules: In silico approach

Author(s):  
Victoria Teniola Adeleke ◽  
Adebayo A Adeniyi ◽  
David Lokhat

Availability of clean water for various activities is a global challenge. Moringa oleifera (MO) seed protein extract has been identified as a natural coagulant for wastewater treatment. The mechanistic understanding...

2016 ◽  
Vol 7 (3) ◽  
pp. 1369-1376 ◽  
Author(s):  
Tan Chu Shan ◽  
Manaf Al Matar ◽  
Essam A. Makky ◽  
Eman N. Ali

Lontara ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 23-30
Author(s):  
A. M. Fadhil Hayat ◽  
St. Mu'tamirah Naim

One alternative to solving the problem of wastewater treatment is to treat wastewater using Moringa seeds as a natural coagulant. Moringa seeds contain the bioactive compound rhamnosyloxy-benzil isothiocyanate, which is able to adsorb and neutralize mud and metal particles contained in suspension waste with dirt particles floating in water, so it is very potential to be used as a natural coagulant to clean water.This research was conducted to determine the method of wastewater treatment by using Moringa Oleifera Seeds for Phosphate (PO4) Content in Hospital Wastewater, and calculating the difference in weight variations of Moringa oleifera seeds (1000, 1500, and 2000 mg / L) with deposition time (15 minutes). This type of research is quantitative research with true experimental research. The research design used was randomized control-group pretest-posttest design.The results showed that in the range of observations made, the weight of Moringa seed powder as an effective coagulant was 2000 mg / L hospital wastewater with a deposition time of 15 minutes capable of removing phosphate levels by 28.77%.


2021 ◽  
Vol 18 (38) ◽  
pp. 214-223
Author(s):  
Olubunmi ATOLANI ◽  
Olufunke Esan OLORUNDARE ◽  
Priyanka BANERJEE ◽  
Oluyomi Stephen ADEYEMI ◽  
Robert PREISSNER

Background: Moringa oleifera seed, which is widely utilized as an affordable source of domestic water treatment, is also reputable for its various pharmacological applications globally. Aim: This study evaluates the toxicity and pharmacological potentials of Moringa oleifera seed protein while establishing the chemical profile. Method: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and liquid chromatography coupled with electrospray ionization mass spectrometry (LC-ESI-MS/MS) were used to analyze the protein/peptide content of the purified protein. The protein was also investigated for in vitro anticancer potential on Hela and MDA-MB-231 cell lines, cytotoxic on 3T3 cell line, and toxicity to brine shrimps. In addition, the antimicrobial action of the protein (polypeptide) was evaluated. Results and Discussion: The MALDI-MS revealed three protein moieties with values of 3.4, 4.6, and 6.9 kDa. On the other hand, LC-ESIMS/MS analysis revealed dipeptides and tripeptides, which include serinylarginine, leucylproline, leucylmethionyl-glycine, isoleucyl-glycyl-methinine, glycyl-arginyl-aspartic acid, isoleucyl-glutamyl-methionine, diphenylalanine, asparaginyl-aspartyl-histidine, seryl-tyrosyl-tyrosine, phenylalanyl-asparaginyl-tyrosine, and propanolyl-trytophanyl-glycine. The seed protein exhibited extremely low toxicity on both 3T3 and MDA-MB-231 breast cancer cell lines, while the standards, doxorubicin, and cycloheximide had IC50 = 0.5 ± 0.07 and 0.8 ± 0.10 μg/mL, respectively. Further, the protein showed no antibacterial or antifungal activity against all tested organisms. The protein also exhibited no lethality against brine shrimp. The in-silico toxicity results indicated that the peptides are not immunotoxic, carcinogenic, or mutagenic as most belonged to the tox class V except serylarginine predicted for tox class IV (harmful if swallowed). Hence, the intake of the protein remnant in water could be within the tolerable limit. Conclusion: The results obtained suggested that the protein content of the Moringa oleifera seed is non-cytotoxic. The result further validates the safety potential of the defatted and debittered seed material used as potential food sources for both humans and animals.


Author(s):  
Ya'’ara Cattan ◽  
Devashree Patil ◽  
Yiftach Vaknin ◽  
Giora Rytwo ◽  
Catriona Lakemond ◽  
...  

Author(s):  
Chen-Jing Sun ◽  
Li-Ping Zhao ◽  
Rui Wang

: With the development of industrialization, the global environmental pollution and energy crisis are becoming increasingly serious. Organic pollutants pose a serious health threat to human beings and other organisms. The removal of organic pollutants in environment has become a global challenge. The photocatalytic technology has been widely used in the degradation of organic pollutants with its characteristics of simple process, high efficiency, thorough degradation and no secondary pollution. However, the single photocatalyst represented by TiO2 has disadvantages of low light utilization rate and high recombination rate of photocarriers. Building heterojunction is considered one of the most effective methods to enhance the photocatalytic performance of single photocatalyst, which can improve the separation efficiency of photocarriers and utilization of visible light. The classical heterojunction can be divided into four different cases: type I, typeⅡ, p–n heterojunctions and Z-scheme junction. In this paper, the recent progress in the treatment of organic pollution by heterostructure photocatalysts is summarized and the mechanism of heterostructure photocatalysts for the treatment of organic pollutants is reviewed. It is expected that this paper can deepen the understanding of heterostructure photocatalysts and provide guidance for high efficient photocatalytic degradation of organic pollutants in the future.


Author(s):  
Huchuan Yan ◽  
Cui Lai ◽  
Dongbo Wang ◽  
Shiyu Liu ◽  
Xiaopei Li ◽  
...  

Refractory organic pollutants in wastewater have the characteristics of persistence and toxicity, which seriously threaten the health and safety of humans and other organisms. Many researchers have committed to developing...


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