Coiled coils and SAH domains in cytoskeletal molecular motors
2011 ◽
Vol 39
(5)
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pp. 1142-1148
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Keyword(s):
Cytoskeletal motors include myosins, kinesins and dyneins. Myosins move along tracks of actin filaments, whereas kinesins and dyneins move along microtubules. Many of these motors are involved in trafficking cargo in cells. However, myosins are mostly monomeric, whereas kinesins are mostly dimeric, owing to the presence of a coiled coil. Some myosins (myosins 6, 7 and 10) contain an SAH (single α-helical) domain, which was originally thought to be a coiled coil. These myosins are now known to be monomers, not dimers. The differences between SAH domains and coiled coils are described and the potential roles of SAH domains in molecular motors are discussed.
2012 ◽
Vol 23
(19)
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pp. 3911-3922
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2018 ◽
Vol 74
(3)
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pp. 194-204
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Keyword(s):
Keyword(s):
2020 ◽
Vol 21
(10)
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pp. 3584
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Keyword(s):
Keyword(s):
Ubiquitination and Long Non-coding RNAs Regulate Actin Cytoskeleton Regulators in Cancer Progression
2019 ◽
Vol 20
(12)
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pp. 2997
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Keyword(s):
2019 ◽
Vol 116
(22)
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pp. 10889-10898
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