“Where is Dementia?” A Systematic Literature Review Exploring Neuroanatomical Aspects of Dementia

2017 ◽  
Vol 2 (15) ◽  
pp. 9-23 ◽  
Author(s):  
Chorong Oh ◽  
Leonard LaPointe
Keyword(s):  
English Language ◽  
Signs And Symptoms ◽  
Behavioral Symptoms ◽  
Journal Articles ◽  
People With Dementia ◽  
Different Types ◽  
Precise Diagnosis ◽  
Physical Changes ◽  
The Brain ◽  
Language Literature

Dementia is a condition caused by and associated with separate physical changes in the brain. The signs and symptoms of dementia are very similar across the diverse types, and it is difficult to diagnose the category by behavioral symptoms alone. Diagnostic criteria have relied on a constellation of signs and symptoms, but it is critical to understand the neuroanatomical differences among the dementias for a more precise diagnosis and subsequent management. With this regard, this review aims to explore the neuroanatomical aspects of dementia to better understand the nature of distinctive subtypes, signs, and symptoms. This is a review of English language literature published from 1996 to the present day of peer-reviewed academic and medical journal articles that report on older people with dementia. This review examines typical neuroanatomical aspects of dementia and reinforces the importance of a thorough understanding of the neuroanatomical characteristics of the different types of dementia and the differential diagnosis of them.

scholarly journals Research Synthesis

2019 ◽  
Vol 83 (3) ◽  
pp. 598-626 ◽  
Author(s):  
Caroline Roberts ◽  
Emily Gilbert ◽  
Nick Allum ◽  
Léïla Eisner
Keyword(s):  
Data Quality ◽  
English Language ◽  
Survey Methodology ◽  
Future Research ◽  
Journal Articles ◽  
Inclusion Criteria ◽  
Response Error ◽  
Response Strategies ◽  
Online Databases ◽  
Different Types

Abstract Herbert Simon’s (1956) concept of satisficing provides an intuitive explanation for the reasons why respondents to surveys sometimes adopt response strategies that can lead to a reduction in data quality. As such, the concept rapidly gained popularity among researchers after it was first introduced to the field of survey methodology by Krosnick and Alwin (1987), and it has become a widely cited buzzword linked to different forms of response error. In this article, we present the findings of a systematic review involving a content analysis of journal articles published in English-language journals between 1987 and 2015 that have drawn on the satisficing concept to evaluate survey data quality. Based on extensive searches of online databases, and an initial screening exercise to apply the study’s inclusion criteria, 141 relevant articles were identified. Guided by the theory of survey satisficing described by Krosnick (1991), the methodological features of the shortlisted articles were coded, including the indicators of satisficing analyzed, the main predictors of satisficing, and the presence of main or interaction effects on the prevalence of satisficing involving indicators of task difficulty, respondent ability, and respondent motivation. Our analysis sheds light on potential differences in the extent to which satisficing theory holds for different types of response error, and highlights a number of avenues for future research.

scholarly journals CHARACTERISTICS AND ANALYTICAL METHODS OF MANNITOL: AN UPDATE

2021 ◽  
pp. 20-32
Author(s):  
ALANKAR SHRIVASTAVA ◽  
SANJAY SHARMA ◽  
MONIKA KAURAV ◽  
ABHISHEK SHARMA
Keyword(s):  
Organic Compound ◽  
Analytical Methods ◽  
English Language ◽  
Glycaemic Index ◽  
Sugar Alcohol ◽  
Compound A ◽  
Search Terms ◽  
Different Types ◽  
Language Literature

Mannitol is an organic compound, a widely distributed natural sugar alcohol in nature. It is found in various plant species and produced by many microorganisms. Mannitol is about 50% as sweet as sucrose, has a low glycaemic index and inert nature, making it suitable to be used in many food products. Mannitol is an osmotic diuretic administering through the iv route and having many clinical usages and is one of the well-known excipients in many different types of formulations. This is also used to increase the dissolution of drugs having solubility problems. Mannitol can be used as a drug and excipient. The goal of this work was to summarize the important physicochemical properties, mechanism of action, production, applications, incompatibilities, polymorphism, and particularly the analytical methodologies published in the last five decades for quantification. Relevant articles related to analytical methods were identified through a search of the English-language literature indexed in Medline, PubMed, ScienceDirect and google scholar from 1970 to till date. The search terms were benign estimation of mannitol, determination of mannitol, methods for determination of mannitol, HPLC and Spectrophotometry method for estimation of mannitol. The methods described in USP, IP, and BP are also described. The presented review also outlines the further scope of research in the field of development of analytical methods.

The Acute Effect of Alcohol on Various Memory Processes

2010 ◽  
Vol 24 (4) ◽  
pp. 249-252 ◽  
Author(s):  
Márk Molnár ◽  
Roland Boha ◽  
Balázs Czigler ◽  
Zsófia Anna Gaál
Keyword(s):  
Low Dose ◽  
Short Term Memory ◽  
Acute Effect ◽  
Long Term Memory ◽  
Term Memory ◽  
Memory Processes ◽  
Different Types ◽  
The Brain ◽  
Legal Consequences

This review surveys relevant and recent data of the pertinent literature regarding the acute effect of alcohol on various kinds of memory processes with special emphasis on working memory. The characteristics of different types of long-term memory (LTM) and short-term memory (STM) processes are summarized with an attempt to relate these to various structures in the brain. LTM is typically impaired by chronic alcohol intake but according to some data a single dose of ethanol may have long lasting effects if administered at a critically important age. The most commonly seen deleterious acute effect of alcohol to STM appears following large doses of ethanol in conditions of “binge drinking” causing the “blackout” phenomenon. However, with the application of various techniques and well-structured behavioral paradigms it is possible to detect, albeit occasionally, subtle changes of cognitive processes even as a result of a low dose of alcohol. These data may be important for the consideration of legal consequences of low-dose ethanol intake in conditions such as driving, etc.

The Impact of Anglicizing Former German-Language Psychology Journals on Authorship and Citation Frequencies

2012 ◽  
Vol 17 (3) ◽  
pp. 190-198 ◽  
Author(s):  
Günter Krampen ◽  
Thomas Huckert ◽  
Gabriel Schui
Keyword(s):  
Side Effects ◽  
English Language ◽  
General Trend ◽  
Native Language ◽  
Impact Factors ◽  
German Language ◽  
Journal Articles ◽  
Number Of Citations ◽  
The Impact ◽  
Number Of Authors

Exemplary for other than English-language psychology journals, the impact of recent Anglicization of five former German-language psychology journals on (1) authorship (nationality, i.e., native language, and number of authors, i.e., single or multiple authorships), (2) formal characteristics of the journal (number of articles per volume and length of articles), and (3) number of citations of the articles in other journal articles, the language of the citing publications, and the impact factors (IF) is analyzed. Scientometric data on these variables are gathered for all articles published in the four years before anglicizing and in the four years after anglicizing the same journal. Results reveal rather quick changes: Citations per year since original articles’ publication increase significantly, and the IF of the journals go up markedly. Frequencies of citing in German-language journals decrease, citing in English-language journals increase significantly after the Anglicization of former German-language psychology journals, and there is a general trend of increasing citations in other languages as well. Side effects of anglicizing former German-language psychology journals include the publication of shorter papers, their availability to a more international authorship, and a slight, but significant increase in multiple authorships.

Tauchnitz for Translators. The Circulation of English-language Literature in Finland

2019 ◽  
Vol 16 (2-3) ◽  
pp. 161-179
Author(s):  
Outi Paloposki
Keyword(s):  
Foreign Language ◽  
English Language ◽  
Book History ◽  
Language Skills ◽  
Point Of View ◽  
Book Production ◽  
German Publisher ◽  
Language Literature ◽  
Selection Of

The article looks at book production and circulation from the point of view of translators, who, as purchasers and readers of foreign-language books, are an important mediating force in the selection of literature for translation. Taking the German publisher Tauchnitz's series ‘Collection of British Authors’ and its circulation in Finland in the nineteenth and early twentieth century as a case in point, the article argues that the increased availability of English-language books facilitated the acquiring and honing of translators' language skills and gradually diminished the need for indirect translating. Book history and translation studies meet here in an examination of the role of the Collection in Finnish translators' work.

Pierre D. Thionet. Quelques problemes concemtlnt les sondages. Goettingen : Vandenhoeck & Ruprecht. 1978. 137pp.

1982 ◽  
Vol 21 (1) ◽  
pp. 83-84
Author(s):  
Karol J. Krotki
Keyword(s):  
Information Theory ◽  
Developing Countries ◽  
Experimental Design ◽  
Bayesian Methods ◽  
English Language ◽  
Applied Statistics ◽  
A Posteriori ◽  
Journal Articles ◽  
Multi Stage ◽  
Theoretical Issues

The publication reviewed is number 9 in the series" Applied Statistics and Econometrics" edited by Gerhard Tintner, Pierre Desire Truonet, and Heinrich Strecker. The purpose of the series is to publish papers " too long for ordinary journal articles, but not long enough for books . ... . . Upon acceptance, speedy publication can be promised". The abstracts in English, French, and German, usual in this series, are missing from the copy reviewed. The book consists of ten chapters: sampling theory; multi -stage sampling and other fundamental problems; optimum stratification; variances; sampling with replacement and other theoretical issues; experimental design; information theory; a posteriori raising factors ; order statistics; Bayesian methods. Such an ambitious content within 130 pages requires parsimonious presentation. One chapter has been squeezed into hardly more than four pages. The chapter on a posteriori raising factors will be useful in developing countries and particularly when samples do not work out as designed. It will also be refreshing to those limited to the literature in the English language.

Types of refractive errors and methods for their diagnosis

2020 ◽  
pp. 30-36
Author(s):  
Olga Lemzyakova
Keyword(s):  
Optical System ◽  
Contact Lenses ◽  
Vision Impairment ◽  
Refractive Errors ◽  
Vision Correction ◽  
Light Rays ◽  
Different Types ◽  
Almost All ◽  
Degrees Of Severity ◽  
The Brain

Refraction of the eye means its ability to bend (refract) light in its own optical system. In a normal state, which is called emmetropia, light rays passing through the optical system of the eye focus on the retina, from where the impulse is transmitted to the visual cortex of the brain and is analyzed there. A person sees equally well both in the distance and near in this situation. However, very often, refractive errors develop as a result of various types of influences. Myopia, or short-sightedness, occurs when the light rays are focused in front of the retina as a result of passing through the optical system of the eye. In this case, a person will clearly distinguish close objects and have difficulties in seeing distant objects. On the opposite side is development of farsightedness (hypermetropia), in which the focusing of light rays occurs behind the retina — such a person sees distant objects clearly, but outlines of closer objects are out of focus. Near vision impairment in old age is a natural process called presbyopia, it develops due to the lens thickening. Both myopia and hypermetropia can have different degrees of severity. The variant, when different refractive errors are observed in different eyes, is called anisometropia. In the same case, if different types of refraction are observed in the same eye, it is astigmatism, and most often it is a congenital pathology. Almost all of the above mentioned refractive errors require correction with spectacles or use of contact lenses. Recently, people are increasingly resorting to the methods of surgical vision correction.

TO THE PROBLEM OF PHRASEOLOGICAL UNITS REFLECTION IN DICTIONARIES OF DIFFERENT TYPES

2020 ◽  
pp. 130-142
Author(s):  
Е.М. Григорьева
Keyword(s):  
Detailed Analysis ◽  
English Language ◽  
Sampling Method ◽  
Semantic Features ◽  
Continuous Sampling ◽  
Translation Equivalent ◽  
Different Types ◽  
Individual Source ◽  
Graphic Illustration ◽  
Characteristic Features

Постановка задачи. Статья посвящена детальному анализу фразеологизмов английского языка различных тематических групп и особенностям их регистрации в англо-английских и англо-русском словарях и справочных пособиях. Рассматривается ряд характеристик, которые отличают фразеологические единицы от свободных словосочетаний. Кроме того, исследуется вопрос включения пословиц в состав фразеологического фонда того или иного языка. Впоследствии отобранные методом сплошной выборки фразеологические единицы классифицируются по различным основаниям, а также проводится детальный анализ особенностей их отражения в представленных изданиях. Результаты. Осуществляется классификация фразеологизмов по следующим категориям: функция в коммуникации, определяемая их структурно-семантическими особенностями, а также тематическое деление. Отдельно рассматриваются фразеологизмы-эвфемизмы, относящиеся к нескольким тематическим группам, среди которых смерть, ругательства и беременность. Выделяются и описываются характерные особенности организации микроструктуры (словарной статьи) каждого отдельно взятого издания. Выводы. На основании проведенного анализа регистрации английских фразеологизмов сделаны выводы о том, что данная лексика получает подробное и точное отражение в справочниках. Проведенный анализ теоретической литературы показал правомерность включения пословиц во фразеологический фонд, поскольку они принадлежат к культурному наследию того или иного народа и воспроизводятся в речи в исходной форме. Тип и адресат справочника определяют особенности организации словарной статьи, а также компоненты, которые входят в нее (дефиниция, переводной эквивалент, иллюстративный пример, грамматическая, стилистическая, региональная и этимологическая пометы, графическая иллюстрация). Statement of the problem. The article is devoted to a detailed analysis of the phraseological units of the English language of various thematic groups and the features of their registration in the English-English and English-Russian dictionaries and reference books. Features that distinguish phraseological units from free phrases are studied. More than that, the question of belonging proverbs to phraseological stock is studied. Then phraseological units selected by the continuous sampling method are classified according to different grounds, and a detailed analysis of the features of their reflection in the analyzed sources is carried out. Results. Phraseological units are classified into some categories according to the following criteria: function in communication, determined by their structural and semantic features and thematic division. Phraseological units-euphemisms related to several thematic groups, including death, curse words and pregnancy are studied. The characteristic features of microstructure organization of each individual source are described. Conclusion. The analysis of English phraseological units registration showed that this lexis is reflected in dictionaries in a proper way. Theoretical literature analysis shows justification of proverbs inclusion into phraseological stock as they are a part of national cultural heritage and are reproduced in speech in the basic form. Further, the author comes to a conclusion that dictionary type and addressee of the reference book determine features of microstructure organization and their components (definition, translation equivalent, illustrative example, grammar, stylistic, regional and etymological labels, graphic illustration).

Ligand and Structure-based Modeling of Passive Diffusion through the Blood-Brain Barrier

2018 ◽  
Vol 25 (9) ◽  
pp. 1073-1089 ◽  
Author(s):  
Santiago Vilar ◽  
Eduardo Sobarzo-Sanchez ◽  
Lourdes Santana ◽  
Eugenio Uriarte
Keyword(s):  
Blood Brain Barrier ◽  
In Silico ◽  
Passive Diffusion ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Blood Brain ◽  
Brain Barrier Permeability ◽  
Different Types ◽  
The Brain

Background: Blood-brain barrier transport is an important process to be considered in drug candidates. The blood-brain barrier protects the brain from toxicological agents and, therefore, also establishes a restrictive mechanism for the delivery of drugs into the brain. Although there are different and complex mechanisms implicated in drug transport, in this review we focused on the prediction of passive diffusion through the blood-brain barrier. Methods: We elaborated on ligand-based and structure-based models that have been described to predict the blood-brain barrier permeability. Results: Multiple 2D and 3D QSPR/QSAR models and integrative approaches have been published to establish quantitative and qualitative relationships with the blood-brain barrier permeability. We explained different types of descriptors that correlate with passive diffusion along with data analysis methods. Moreover, we discussed the applicability of other types of molecular structure-based simulations, such as molecular dynamics, and their implications in the prediction of passive diffusion. Challenges and limitations of experimental measurements of permeability and in silico predictive methods were also described. Conclusion: Improvements in the prediction of blood-brain barrier permeability from different types of in silico models are crucial to optimize the process of Central Nervous System drug discovery and development.

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