scholarly journals How does an athlete’s heart react to studying at university?

2020 ◽  
Vol 26 ◽  
pp. 00053
Author(s):  
Tatiana Popova ◽  
Yurj Koriukalov ◽  
Olga Kourova ◽  
Vladimir Gurlev ◽  
Tatiana Khomykova
Keyword(s):  
Heart Rate ◽  
Muscular Activity ◽  
Cognitive Test ◽  
Stress Index ◽  
Health Improvement ◽  
Pronounced Increase ◽  
Postgraduate Students ◽  
Arterial Blood ◽  
Fatigue Development ◽  
Functional Stress

2 groups of participants have been studied: I – student-athletes; II – students and postgraduate students, not involved in sport. The functional status of the heart has been studied in three conditions: at rest, during the cognitive test, and under local static load (the wrist dynamometer). The electroencephalography has also been applied. Results demonstrated a statistical decrease in wrist endurance in all participants during the academic year. They proved fatigue development. A pronounced increase of heart rate and arterial blood pressure, as well as the increase of heart rate variability mode and stress index under local load and during the cognitive test, proved the development of the heart functional stress, especially in athletes. Electroencephalography data prove the central origin of adaptation reactions both to mental and to local muscular activity. Disease prevention and health improvement measures are necessary for university students actively involved in sport. One of such measures is relaxation exercises aimed at a decrease in functional stress.

PENGARUH TINDAKAN MOBILISASI DINI TERHADAP DENYUT JANTUNG DAN FREKUENSI PERNAPASAN PADA PASIEN KRITIS DI ICU RSUD SLEMAN YOGYAKARTA

2019 ◽  
Vol 5 (3) ◽  
pp. 213-223
Author(s):  
Muhamat Nofiyanto ◽  
Tetra Saktika Adhinugraha
Keyword(s):  
Heart Rate ◽  
Respiratory Rate ◽  
Early Mobilization ◽  
Critical Conditions ◽  
P Value ◽  
Cardiorespiratory Function ◽  
Arterial Blood ◽  
Post Test ◽  
Critical Patients ◽  
Security Standards

Background: Patients with critical conditions in the ICU depend on a variety of tools to support their lifes. Patients’ conditions and and their unstable hemodynamic are challenges for nurses to perform mobilization. Less mobilization in critical patients can cause a variety of physical problems, one of them is cardiorespiratory function disorder. Objective: to investigate differences in heart rate (HR) and respiratory rate (RR) before, during, and immediately after early mobilization. Methods: This study employed quasi experiment with one group pre and post test design. Twenty four respondents were selected based on the criteria HR <110 / min at rest, Mean Arterial Blood Pressure between 60 to 110 mmHg, and the fraction of inspired oxygen <0.6. Early mobilization was performed to the respondents, and followed by assessments on the changes of respiratory rate and heart rate before, during, and immediately after the mobilization. Analysis of differences in this study used ANNOVA. Results: Before the early mobilization, mean RR was 22.54 and mean HR was 78.58. Immediately after the mobilization,  mean RR was 23.21 and mean HR was 80.75. There was no differences in the value of RR and HR, before and immediately after the early mobilization with the p-value of 0.540 and 0.314, respectively. Conclusions: Early mobilization of critical patients is relatively safe. Nurses are expected to perform early mobilization for critical patients. However, it should be with regard to security standards and rigorous assessment of the patient's conditions. Keywords: Early mobilization, critical patients, ICU

Compression Stocking Length Effects on Arterial Blood Pressure and Heart Rate Following Head-Up Tilt in Healthy Volunteers

2014 ◽  
Vol 63 (6) ◽  
pp. 435-438 ◽  
Author(s):  
Kunihiko Tanaka ◽  
Shiori Tokumiya ◽  
Yumiko Ishihara ◽  
Yumiko Kohira ◽  
Tetsuro Katafuchi
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Healthy Volunteers ◽  
Arterial Blood Pressure ◽  
Compression Stocking ◽  
Arterial Blood ◽  
Head Up Tilt ◽  
Length Effects

A Comparison of the Acute Haemodynamic Effects of Propranolol and Pindolol at Rest and during Supine Exercise in Man

1980 ◽  
Vol 59 (s6) ◽  
pp. 465s-468s ◽  
Author(s):  
T. L. Svendsen ◽  
J. E. Carlsen ◽  
O. Hartling ◽  
A. McNair ◽  
J. Trap-Jensen
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiac Output ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Response Curves ◽  
Receptor Blocking ◽  
Artery Pressure ◽  
Arterial Blood ◽  
Β Receptor

1. Dose-response curves for heart rate, cardiac output, arterial blood pressure and pulmonary artery pressure were obtained in 16 male patients after intravenous administration of three increasing doses of pindolol, propranolol or placebo. All patients had an uncomplicated acute myocardial infarction 6–8 months earlier. 2. The dose-response curves were obtained at rest and during repeated bouts of supine bicycle exercise. The cumulative dose amounted to 0.024 mg/kg body weight for pindolol and to 0.192 mg/kg body weight for propranolol. 3. At rest propranolol significantly reduced heart rate and cardiac output by 12% and 15% respectively. Arterial mean blood pressure was reduced by 9.2 mmHg. Mean pulmonary artery pressure increased significantly by 2 mmHg. Statistically significant changes in these variables were not seen after pindolol or placebo. 4. During exercise pindolol and propranolol both reduced cardiac output, heart rate and arterial blood pressure to the same extent. After propranolol mean pulmonary artery pressure was increased significantly by 3.6 mmHg. Pindolol and placebo did not change pulmonary artery pressure significantly. 5. The study suggests that pindolol may offer haemodynamic advantages over β-receptor-blocking agents without intrinsic sympathomimetic activity during low activity of the sympathetic nervous system, and may be preferable in situations where the β-receptor-blocking effect is required only during physical or psychic stress.

scholarly journals Salt sensitivity of blood pressure in NKCC1-deficient mice

2008 ◽  
Vol 295 (4) ◽  
pp. F1230-F1238 ◽  
Author(s):  
Soo Mi Kim ◽  
Christoph Eisner ◽  
Robert Faulhaber-Walter ◽  
Diane Mizel ◽  
Susan M. Wall ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Wheel Running ◽  
Plasma Renin ◽  
Pressure Change ◽  
Standard Diet ◽  
Wild Type ◽  
Vascular Effects ◽  
Arterial Blood ◽  
Deficient Mice

NKCC1 is a widely expressed isoform of the Na-2Cl-K cotransporter that mediates several direct and indirect vascular effects and regulates expression and release of renin. In this study, we used NKCC1-deficient (NKCC1−/−) and wild-type (WT) mice to assess day/night differences of blood pressure (BP), locomotor activity, and renin release and to study the effects of high (8%) or low (0.03%) dietary NaCl intake on BP, activity, and the renin/aldosterone system. On a standard diet, 24-h mean arterial blood pressure (MAP) and heart rate determined by radiotelemetry, and their day/night differences, were not different in NKCC1−/− and WT mice. Spontaneous and wheel-running activities in the active night phase were lower in NKCC1−/− than WT mice. In NKCC1−/− mice on a high-NaCl diet, MAP increased by 10 mmHg in the night without changes in heart rate. In contrast, there was no salt-dependent blood pressure change in WT mice. MAP reductions by hydralazine (1 mg/kg) or isoproterenol (10 μg/mouse) were significantly greater in NKCC1−/− than WT mice. Plasma renin (PRC; ng ANG I·ml−1·h−1) and aldosterone (aldo; pg/ml) concentrations were higher in NKCC1−/− than WT mice (PRC: 3,745 ± 377 vs. 1,245 ± 364; aldo: 763 ± 136 vs. 327 ± 98). Hyperreninism and hyperaldosteronism were found in NKCC1−/− mice during both day and night. High Na suppressed PRC and aldosterone in both NKCC1−/− and WT mice, whereas a low-Na diet increased PRC and aldosterone in WT but not NKCC1−/− mice. We conclude that 24-h MAP and MAP circadian rhythms do not differ between NKCC1−/− and WT mice on a standard diet, probably reflecting a balance between anti- and prohypertensive factors, but that blood pressure of NKCC1−/− mice is more sensitive to increases and decreases of Na intake.

Abstract MP45: Deletion Of The Transient Receptor Vanilloid-1 (TRPV1) Channel In Rats Attenuates 2 Kidney 1 Clip Hypertension

Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Sean D Stocker ◽  
Leon J DeLalio
Keyword(s):  
Heart Rate ◽  
Renovascular Hypertension ◽  
Sensory Nerve ◽  
Experimental Models ◽  
Sensory Nerves ◽  
Male Rats ◽  
Wild Type ◽  
Renal Nerve ◽  
Trpv1 Channels ◽  
Arterial Blood

Renal denervation lowers arterial blood pressure (ABP) in both clinical populations and multiple experimental models of hypertension. This therapeutic effect is partly attributed to the removal of overactive renal sensory nerves that increase sympathetic efferent activity and ABP. Renal sensory nerves highly express TRPV1 channels, and administration of the TRPV1 agonist capsaicin increases renal sensory nerve activity. However, the extent by which TRPV1 channels directly contribute to renal nerve dependent models of hypertension has not been tested. To test this hypothesis, we generated a novel TRPV1 -/- rat using CRISPR/Cas9 and deletion of exon 3. Male and female TRPV1 -/- and wild-type littermates (8-12 weeks) were instrumented with telemetry. At 2 weeks later, renovascular hypertension via renal stenosis was produced by placement of a PTFE cuff (0.16 x 0.22 inches, 1mm long) around the right renal artery. Male TRPV1 -/- and wild-type rats had no differences in baseline mean ABP (99±2 vs 98±3 mmHg, respectively; n=7-9) or heart rate (390±7 vs 400±8 bpm, respectively). Renal stenosis significantly increased mean ABP in both groups; however, mean ABP was significantly lower at Day 28 in male TRPV1 -/- versus wild-type rats (125±8 vs 155±2 mmHg, respectively: P<0.01). Ganglionic blockade with chlorisondamine (2.5mg/kg, sc) at Day 28 produced a smaller fall in mean ABP of male TRPV1 -/- versus wild-type rats (-53±4 vs -86±3 mmHg, respectively; P<0.001). On the other hand, female TRPV1 -/- and wild-type rats had no differences in baseline mean ABP (102±2 vs 104±1 mmHg, respectively; n=6-9) or heart rate (419±8 vs 410±7 bpm, respectively). Renal stenosis significantly increased mean ABP in both groups; however, there were no differences at Day 28 between female TRPV1 -/- versus wild-type rats (117±8 vs 122±6 mmHg, respectively). Moreover, the increase in mean ABP was smaller in females versus males. The ganglionic blocker chlorisondamine produced similar depressor responses in female TRPV1 -/- versus wild-type rats (-64±7 vs -65±7 mmHg, respectively). These findings illustrate a sex difference in renovascular hypertension in rats, but importantly indicate that TRPV1 channels contribute to the established phase of renovascular hypertension in male rats.

Features of the long-term dynamics of heart rate variability among workers of a potash ore processing enterprise

2021 ◽  
Vol 61 (7) ◽  
pp. 442-450
Author(s):  
Alexandr E. Nosov ◽  
Nina V. Zaitseva ◽  
Vitalii G. Kostarev ◽  
Julia A. Ivashova ◽  
Maksim A. Savinkov ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Significant Relationship ◽  
Work Experience ◽  
Fine Particles ◽  
Comparison Group ◽  
Stress Index ◽  
Observation Group ◽  
Ore Processing ◽  
Processing Enterprise

Introduction. Currently, the violation of heart rate variability as one of the main pathogenetic mechanisms of the damaging effect of pollutants, associated effects on the cardiovascular system. The study aims to explore the dynamics of the influence of the autonomic nervous system (ANS) on heart rate variability (HRV) in workers of a potassium ore processing enterprise exposed to industrial pollutants (fine fractions of potassium chloride dust, formaldehyde, hexane, heptane) with an assessment of changes in dependence from work experience, establishment of cause-and-effect relationships of violations of heart rate variability with exposure to chemical compounds. Materials and methods. The object of the study was 140 employees of a potash ore processing enterprise, assigned to the observation group, and 76 employees of the administrative and technical apparatus, who made up the comparison group. Samples were taken from the air of the working medium for the content of saturated hydrocarbons (hexane, heptane), the vapors of formhehyde were considered, and the presence of fine particles PM2.5 and PM10 was established. Investigation of biological media (blood, urine) of workers at the enterprise determination of formaldehyde in blood, hexane and heptane in urine. Evaluation of heart rate variability was carried out on a computer electrocardiograph "Poli-Spectr-8/EX" using a cardiorhythmographic program using the method of time analysis, variation pulsometry and spectral analysis. Results. The concentration of fine particles in the air at the workplaces of the observation group was 12-111 times higher for PM2.5, and 5.6-74.6 times higher for PM10 than for the work places of the comparison group. The concentration of formaldehyde, hexane and heptane in the air did not exceed hygienic standards. In the observation group relative to the comparison group, formaldehyde blood was 1.5 times (p<0.001), in the urine of hexane - 1.2 times (p=0.011), heptane - 1.3 times (p=0.046). It was found that with an experience of up to 10 years, formaldehyde in the blood of workers in the observation group was 1.4 times higher than that in the comparison group (p=0.011), with an experience of more than 10 years - 1.7 times (p=0.005). In the urine of workers in the observation group with work experience of up to 10 years, an excess of 1.3 (p=0.026) relative to the comparison group of hexane was found. HRV data analysis. With damage to the length of service in the observation group, there was a significant decrease in the temporal analysis indicators (SDNN, ms, RMSSD, ms, pNN50, %, CV, %), while in the comparison group, only the CV, % decrease was statistically significant; the values of IN conventional units, AMo, % significantly increased (p=0.03 and p=0.003, respectively). A statistically significant relationship was established between the likelihood of an increase depending on the content of heptane in urine (b0=0.22; b1=10.6; F=21.5; R2=0.09; p=0.0001) and formaldehyde in the blood (b0=0.02; b1=6.55; F=69.6; R2=0.25; p=0.0001) in the surveyed workers. Conclusions. Activation of central ergotropic and humoral-metabolic mechanisms, a tendency towards a decrease in parasympathetic influences. The method of logistic regression analysis established a statistically significant relationship between the probability of an increase in the stress index depending on the heptane content in the blood of the surveyed suppliers.

Chemoreflex and endocrine components of cardiovascular responses to acute hypoxemia in the llama fetus

1996 ◽  
Vol 271 (1) ◽  
pp. R73-R83 ◽  
Author(s):  
D. A. Giussani ◽  
R. A. Riquelme ◽  
F. A. Moraga ◽  
H. H. McGarrigle ◽  
C. R. Gaete ◽  
...  
Keyword(s):  
Heart Rate ◽  
Angiotensin Ii ◽  
High Altitude ◽  
Chronic Exposure ◽  
Perfusion Pressure ◽  
Carotid Sinus ◽  
Cardiovascular Responses ◽  
Pronounced Increase ◽  
Plasma Vasopressin ◽  
Plasma Angiotensin

We tested the hypothesis that the llama fetus has a blunted cardiovascular chemoreflex response to hypoxemia by investigating the effects of acute hypoxemia on perfusion pressure, heart rate, and the distribution of the combined ventricular output in 10 chronically instrumented fetal llamas at 0.6-0.7 gestation. Four llama fetuses had the carotid sinus nerves sectioned. In the intact fetuses, there was a marked bradycardia, an increase in perfusion pressure, and a pronounced peripheral vasoconstriction during hypoxemia. These cardiovascular responses during hypoxemia in intact fetuses were accompanied by a pronounced increase in plasma vasopressin, but not in plasma angiotensin II concentrations. Carotid denervation prevented the bradycardia at the onset of hypoxemia, but it did not affect the intense vasoconstriction during hypoxemia. Plasma vasopressin and angiotensin II levels were not measured in carotid-denervated fetuses. Our results do not support the hypothesis that the carotid chemoreflex during hypoxemia is blunted in the llama fetus. However, they emphasize that other mechanisms, such as increased vasopressin concentrations, operate to produce an intense vasoconstriction in hypoxemia. This intense vasoconstriction in the llama fetus during hypoxemia may reflect the influence of chronic exposure to the hypoxia of high altitude on the magnitude and gain of fetal cardiovascular responses to a superimposed acute episode of hypoxemia.

scholarly journals Cardiovascular effects of lumbar epidural anaesthesia in isoflurane-anaesthetised pigs during surgical removal of the liver

2009 ◽  
Vol 80 (1) ◽  
Author(s):  
G.F. Stegmann
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Abdominal Surgery ◽  
Epidural Anaesthesia ◽  
Cardiovascular Effects ◽  
Surgical Removal ◽  
Arterial Blood ◽  
Combined Administration ◽  
Lumbar Epidural Anaesthesia ◽  
Surgical Preparation

In humans the combined administration of epidural anaesthesia and inhalation anaesthesia may result in cardiovascular instability associated with decreases in heart rate and blood pressure. Anaesthesia was induced with a combination of midazolam / ketamine in 18 female pigs with a mean body weight of 24.9±5.9 kg scheduled for surgical removal of the liver. After tracheal intubation, anaesthesia was maintained on a circle rebreathing circuit with isoflurane. Epidural anaesthesia was administered with ropivacaine (AL-group, n=8) at 0.2 mℓ / kg of a 7.5 mg / mℓ solution to the anaesthetised animals. The A-group (n = 10) received isoflurane anaesthesia only. The vaporiser was set at 2.5 % for the A-group and 1.5 % for the AL-group. Heart rate, invasive systolic, diastolic, and mean arterial blood pressure were monitored. Comparisons were made between treatments and within treatments comparing variables during surgical preparation and abdominal surgery. Differences between treatments were not statistically significant (P > 0.05) during surgical preparation or during abdominal surgery. For within treatment groups, the differences between surgical preparation and abdominal surgery were statistically significant (P < 0.05) for heart rate in the A-group, but not statistically significant (P > 0.05) for the other variables. It is concluded that abdominal surgery may be associated with statistically significant changes in heart rate in isoflurane-anaesthetised pigs and that the combined administration of epidural ropivacaine may prevent statistically significant changes in HR during abdominal surgery.

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