scholarly journals Iodine deficiency: socio-economic problems and new approaches to its solution in veterinary medicine

2021 ◽  
Vol 32 ◽  
pp. 04002
Author(s):  
Alexey Yevglevsky ◽  
Andrey Gostev

One of the global, vital problems of humanity is iodine deficiency. According to the World Health Organization (WHO), more than 2 billion people live in conditions of iodine deficiency. people: among them, 740 million have endemic goiter, 43 million have mental retardation, more than 6 million. they suffer from cretinism (an extreme degree of mental retardation). Currently, iodine deficiency diseases are the most common non-infectious diseases in the world. What about mammalian animals? In animals, iodine performs the same functions as in humans. Animals, especially agricultural animals, are just as sensitive to iodine deficiency as humans. With a lack of iodine in the body of animals, the biosynthesis of thyroid hormones is disrupted, which leads to a decrease in the intensity of redox processes, as a result of which all types of metabolism are disrupted:-protein, fat, carbohydrate, macro – and microelement, energy. In this regard, the failure of the thyroid gland is accompanied by the development of severe pathobiochemical processes, which, in the end, leads to the clinical manifestation of pathophysiological conditions. Taking into account the fact that in conditions of constant iodine deficiency it is very problematic to ensure the health of productive animals, the issues of prevention of iodine deficiency conditions are economically significant for industrial animal husbandry. It is no accident that in countries experiencing natural iodine deficiency, state programs have been developed that provide for the use of iodine-containing additives in the diets of productive animals. Despite the fact that the simplest and most affordable method of eliminating iodine deficiency in humans and animals is the inclusion of iodized salt in the diet, however, this method can not be used for veterinary purposes. First of all, the feed method of using biologically active additives eliminates the possibility of dosed therapeutic or preventive treatment. On the pages of this article, we draw attention to the emerging prospects for the use of a new iodine-metabolic composition in non-infectious and infectious pathology, based on an iodine polymer complex known in pharmacology as iodinol and succinic acid.

2020 ◽  
Vol 21 (2) ◽  
pp. 93-111
Author(s):  
Sergey Brankovich Bolevich ◽  
Peter Frantzevich Litvitsky ◽  
Sergei Vitalievich Grachev ◽  
Sergey Ivanovich Vorobyev ◽  
Alexandra Sergeevna Orlova ◽  
...  

AbstractAt the end of 2019, a new coronavirus infection occurred in the People’s Republic of China with an epicentre in the city of Wuhan. On February 11th, 2020, the World Health Organization assigned the official name of the infection caused by the new coronavirus – COVID-19. COVID-19 has affected people from all over the world given that the infection was noted in 200 countries resulting in annunciation of the pandemic situation. Human corona viruses cause mild to moderate respiratory infections. At the end of 2002, a new coronavirus appeared (SARS-CoV), the causal agent of atypical pneumonia, which caused acute respiratory distress syndrome (ARDS). The initial stage of COVID-19 infection is the penetration of SARS-CoV-2 into target cells that have angiotensin converting enzyme type II receptors. The virus enters the body through the respiratory tract and interacts primarily with toll-like receptors (TLRs). The events in SARS-Cov-2 induced infection follow the next scenario: epithelial cells via TLRs recognize and identify SARS-Cov-2, and after that the information is transmitted to the transcriptional NF-κB, which causes expression of the corresponding genes. Activated in this way, the epithelial cells begin to synthesize various biologically active molecules. The results obtained on preclinical material indicate that ROS generation increases and the antioxidant protection decreases, which plays a major role in the pathogenesis of SARS-CoV, as well as in the progression and severity of this respiratory disease.


2013 ◽  
Vol 51 (2) ◽  
pp. 113-116 ◽  
Author(s):  
Marc J. Tassé

Abstract The World Health Organization (WHO) is in the process of developing the 11th edition of the International Classification of Diseases (ICD–11). Part of this process includes replacing mental retardation with a more acceptable term to identify the condition. The current international consensus appears to be replacing mental retardation with intellectual disability. This article briefly presents some of the issues involved in changing terminology and the constraints and conventions that are specific to the ICD.


Leprosy ◽  
2020 ◽  
pp. 1-19
Author(s):  
Charlotte A. Roberts

This chapter introduces leprosy, an infection that is still misunderstood and considered a neglected tropical disease but declining in frequency, according to the World Health Organization. The bacteria that cause leprosy, Mycobacterium leprae and Mycobacterium lepromatosis, are outlined, as well as how a relative strength of a person’s immune system determines how leprosy affects the body. Although leprosy is curable, associated stigma and disability remain common challenges for people with the disease in parts of the world. The goals and structure of the book are outlined, ten myths that still pervade society at large are listed, and the use of the word “leper” discussed. Based on World Health Organization data, the chapter also explores the frequency of leprosy today, where the infection remains a challenge, and the history of detecting and reporting evidence for leprosy in living populations. Finally, the reasons why bioarchaeologists have an interest in this infection are explored.


2020 ◽  
Vol 21 (10) ◽  
pp. 3570 ◽  
Author(s):  
Katarzyna Zorena ◽  
Olga Jachimowicz-Duda ◽  
Daniel Ślęzak ◽  
Marlena Robakowska ◽  
Małgorzata Mrugacz

The World Health Organization (WHO) has recognized obesity as one of the top ten threats to human health. It is estimated that the number of obese and overweight people worldwide exceeds the number of those who are undernourished. Obesity is not only a state of abnormally increased adipose tissue in the body, but also of increased release of biologically active adipokines. Adipokines released into the circulating blood, due to their specific receptors on the surface of target cells, act as classic hormones affecting the metabolism of tissues and organs. What is more, adipokines and cytokines may decrease the insulin sensitivity of tissues and induce inflammation and development of chronic complications. Certainly, it can be stated that in an era of a global obesity pandemic, adipokines may gain more and more importance as regards their use in the diagnostic evaluation and treatment of diseases. An extensive search for materials on the role of white, brown and perivascular fatty tissue and obesity-related metabolic and chronic complications was conducted online using PubMed, the Cochrane database and Embase.


2019 ◽  
Vol 6 (1) ◽  
pp. 14-20
Author(s):  
Betti Rosita ◽  
Helvina Mustika

Based on the results of a survey conducted by the World Health Organization (WHO) in 2012, the number of active smokers in the world has reached more than 1 billion people. This number is expected to continue to increase given the high prevalence of world cigarette consumption rates, while in Indonesia it is found that almost every year the number of smokers is increasing. Cigarettes containing chemicals including carbon monoxide, nicotine, tar, ammonia, arsenic, cyanide and lead (Pb) The main effect is lead that is inhaled and enters the respiratory system will also circulate throughout the tissues and organs of the body. More than 90% of lead metal absorbed by blood binds to red blood cells and results in a disruption in the process of hemoglobin synthesis. The purpose of this study is to determine the level of lead metal toxicity with an overview of smear preparations in the blood of active smokers. The research method with simple random sampling, samples taken capillary blood and making blood smear preparations that were examined with a microscope while examining the metal in the urine using Atomic Absorption Spectrophotometer (AAS). The results of the study of lead content in urine of active smokers found that the high is 0.384 mg / dl and the low lead level is 0.002 mg / dl positive containing lead in the urine with the amount of lead content exceeding the threshold and from the results of the smear dosage found that normal or normociter cell size can be obtained normal or normochrome (1/3 of the center is pale) whereas abnormalities in the cell form are teardrop cells, ovalocytes, schistocyte, this is due to the effect of lead that disrupts health especially usually occurs in haemotopoetic systems (blood formation system)


2021 ◽  
Vol 11 (3) ◽  
pp. 1-2

Every year on 24 March, World Tuberculosis Day is commemorated annually, for raising the public awareness regarding devastating consequences of tuberculosison health and economic aspects of life. This helps to launch efforts to end the globalepidemic of tuberculosis. On the date of 24th March in 1882, Dr. Robert Koch announced about the discovery of bacterium that causes tuberculosis.1 It was held on 24th March 1982 first time by The World Health Organization at the 100th anniversary of Dr. Koch’s discovery. The target 3.3 of SDG calls for, by 2030, ending the epidemics of tuberculosis, malaria, AIDS, combat other communicable and water-borne diseases. A large number of people 1.7 billion, roughly 23% of the world's population suffered from tuberculosis. In the world, each year 1.5 million people died due to TB, proving it a leading infectious killer disease. Thirty countries having the high burden of TB, accounted for 87% of new TB cases during 2019.2 Among these, two thirds of the total cases were in India, Indonesia, China, Bangladesh, Philippines, Pakistan, Nigeria, and South Africa. An estimated 510,000 new TB cases are emerging each year in Pakistan. Among these about, 15 000 are developing drug resistant TB cases. Pakistan is bearing 61% of the TB burden in the EMRO. Tuberculosis is preventable and curable disease. The causative agent of tuberculosis, Mycobacterium tuberculosis, most often affect the lungs. The vaccine for tuberculosis (TB) disease is called BCG (Bacille Calmette-Guérin). In 1921, first patient was vaccinated with BCG vaccine, 13 years were spent in the making the vaccine. In countries where TB is common, BCG vaccine is given to infants and small children. It does not always protect people from getting TB. BCG vaccine is included in national Expanded Program on Immunization (EPI) in Pakistan and given at birth. To make TB free Pakistan through universal access to quality TB care, National TB Control Program (NTP) is striving for achieving Zero TB death by reducing 50% prevalence of TB in general population by 2025. The mode of transmission of TB from person to person is through the air. The TB germs are propelled into the air,when people with lung TB cough, sneeze or spit carelessly due to lack of awareness that they are participating in the spread of disease and weakening the efforts. These germs are when inhaled by other people, resulting in lung infection, which is called primary TB. From primary TB infection, majority of people recover withoutany further evidence of the disease. For years the infection may stay inactive (latent). People with TB infection are not contagious, do not have any symptoms, and do not put their friends, co-workers and family at risk. Many people who have latent TB infection never develop TB disease. In these people, the TB bacteria remain inactive for a lifetime without causing disease. But in other people, especially people who have weak immune systems, the bacteria become active, multiply, and cause TB disease. There is good news for people with TB disease! It can almost always be treated and cured with medicine. But the medicine must be taken as directed by Physician. The relapse rate differs by a country's incidence and control: 0–27% of TB relapses occur within 2 years after treatment completion and most relapses occur within 5 years; however, some relapses occur 15 years after treatment. A person who has genital tuberculosis can infect others through sexual contact. The most common means of spreading genital TB can be through blood or lymph. Hence, sexual contact can spread genital tuberculosis. Genital tuberculosis can spread to any other body organ, once it enters the body. Consuming a diet high in nutritious foods and beverages is a smart way to support and protect lung health. Coffee, dark leafy greens, fatty fish, peppers, tomatoes, olive oil, oysters, blueberries, and pumpkin are just some examples of foods and drinks that have been shown to benefit lung function. Milk can be used by TB patient. It is also a great source of protein, providing strength necessary to perform day-to-day activities. Directly observed treatment, short-course (DOTS, also known as TB-DOTS) is the name given to the tuberculosis (TB) control strategy recommended by the World Health Organization. According to WHO, "The most cost-effective way to stop the spread of TB in communities with a high incidence is by curing it. The usual treatment is: two antibiotics (isoniazid and rifampicin) for 6 months, two additional antibiotics (pyrazinamide and ethambutol) for the first 2 months of the 6-month treatment period. Groups with high rates of TB transmission are homeless persons, injection drug users, and persons with HIV infection are more susceptible for TB and persons who have immigrated from areas of the world with high rates of TB. The disease is prevalent mainly in the underprivileged sections of the society. The lack of knowledge in the masses and the communities is a factor that contributes largely to the spread of the disease. The theme of World TB Day 2020 was “It's TIME to end TB” and in 2021 it is,” Am I stopping TB” highlighting the importance of awareness. It is the time to fuel the awareness program with full energy, resources and ways. In such a scenario, there is always a need for new and innovative ideas to create mass awareness about tuberculosis. The more focus of this awareness campaign should be very much targeted towards people living in an area where there are a lot of people are with TB, or have been homeless or live in poorly ventilated or overcrowded housing and sufferers of a weakened immune system.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Getachew Seid ◽  
Tsegaye Tsedalu ◽  
Marta Ayele ◽  
Faham Khamesipour

Background. The World Health Organization recommends that all children below the age of five who have household contact with an infectious tuberculosis case should receive isoniazid preventive treatment for at least six months after the active tuberculosis disease has been ruled out. This research aims to determine the adherence of children, eligible for isoniazid preventive treatment, to the treatment who had contact with pulmonary tuberculosis patients. Methods. A mixed study design was used to prospectively assess the adherence to IPT among children under the age of 5 in contact with pulmonary TB patients through the quantitative study design and barriers of adherence in view of health care professionals and the family of children through a descriptive qualitative study. The study was conducted from July 2019 to December 2019 in Addis Ababa. Data were collected by a structured datasheet from the selected health center registration book. Data were entered into Epi Data software and analyzed by using SPSS version 20. Descriptive statistical methods were used to summarize the sociodemographic characteristics of the study participants. Result. The ratio of the total number of pulmonary tuberculosis index cases recruited into the study to the number of child contacts aged less than 5 years was 1 : 1.32. The total isoniazid preventive treatment uptake in this study was 75.2%; one-fifth (21.3%) of the children who started IPT did not complete the full course of six-month isoniazid preventive treatment. Except for HIV not to be tested ( P < 0.001 ), there was no significant association of the listed risk factors in default to complete the full six months of preventive treatment. Conclusion. Enrolment of eligible children for isoniazid preventive treatment in the urban city Addis Ababa was still below the target of the World Health Organization End tuberculosis strategy by 2030. The treatment adherence rate also needs a great deal of effort to achieve the strategy. Child default after the first visit indicates a lack of understanding about the benefit and safety of preventive therapy in young children among families of TB patients, and awareness-creating efforts by health extension workers will help to improve the outcomes.


2020 ◽  
Vol 02 (03) ◽  
pp. 21-24
Author(s):  
Gulara Rufat Sadikhova ◽  
◽  
Sayali Yolchu gizi Ibrahimova ◽  

It is common knowledge that the Diabetes is a widespread disease of the endocrine system. To outline the main points, it is worth too say that Diabetes is a chronic disease associated with an absolute or relative deficiency of the hormone insulin, wherein the insulin secreted by the pancreas and cleaves the glucose in the blood. Diabetes affects many organ systems of the body so that the most severe complication of the disease is coma. Therefore, in the treatment of the disease, sugar-reducing drugs and mandatory diet are used. It comes as no surprise that almost 422 mln of the world's population suffer from Diabetes, as it is stipulates by the World Health Organization statistics. Key words: Diabetes, hormone insulin, diet, coma


2021 ◽  
Vol 3 (2) ◽  
pp. 178
Author(s):  
Dwi Kartika Pebrianti ◽  
Armina Armina

The case of the Corona Virus is known through a mysterious disease that paralyzed the City of Wuhan, China. The tragedy at the end of 2019 has continued until the spread of the Corona virus has spread throughout the world. Quoted from CNN, here are some things that must be known about the development of the Corona virus, which is commonly called the Corona virus or COVID-19, until it broke out and became a pandemic. Everyone needs to maintain mental health to avoid physical complaints that arise due to stress. Because when someone is stressed, the immune system in the body will decrease. This will cause the body to be susceptible to disease. Realizing that anxiety due to COVID-19 has pervaded many communities, the World Health Organization (WHO) in March 2020 released a guide for people to jointly maintain mental health. Through community service activities by directly interacting with the community while still implementing the COVID-19 protocol, socialization was carried out about the importance of maintaining mental health in the community during the Covid-19 Pandemic. Community service at RT 30 Recognize Besar, the community can know, recognize and overcome how to recognize mental health disorders including anxiety and depression, it is hoped that the community will always think optimistically in facing the Covid-19 pandemic, by implementing health protocols, maintaining a healthy lifestyle, regular exercise, always think positively, maintain communication with family and friends


2021 ◽  
Vol 1 (1) ◽  
pp. 387-410
Author(s):  
Erna Martiyani ◽  
Farah Maulida Rahmah ◽  
Marisa Amalia Citra ◽  
Medinio Leonita KS

Exclusive breastfeeding is that babies are only given breast milk, without the addition of other liquids such as formula milk, orange juice, honey, tea water, water, and without the addition of solid foods such as bananas, papaya, milk porridge, biscuits, rice porridge, and the team, as long as 6 months from the date of birth. Data from the World Health Organization (WHO) in 2016 still shows that the average rate of exclusive breastfeeding in the world is only around 38%. This study aims to determine the description of exclusive breastfeeding in infants in Java. Qualitative research using a descriptive observational study design that is conducting in-depth interviews with 4 informants which are by the interview guidelines. The results showed that the mother's age can affect the exclusive breastfeeding for the baby because the younger mother will produce more milk than the older mother. While the knowledge variable shows the results that mothers who have high knowledge about exclusive breastfeeding have a 20.8 times chance compared to mothers who have low knowledge. The existence of family support can also increase the mother's confidence in breastfeeding and the support from health workers can increase knowledge and motivate mothers to give exclusive breastfeeding. Based on this, we can say that breast milk is a perfect food that contains various nutrients that are needed by the body of living beings so that the body's metabolism can run smoothly and the development of the body goes well.


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