scholarly journals Research on the Neurobiology of COVID-19

2021 ◽  
Vol 245 ◽  
pp. 03045
Author(s):  
Yilun Tong
Keyword(s):  
Nervous System ◽  
Molecular Mechanism ◽  
The Novel ◽  
Neurologic Manifestations ◽  
Neurological Manifestations ◽  
Corona Virus ◽  
The World ◽  
Human Nervous System ◽  
Different Parts

More studies have shown the neurological manifestations of the novel corona virus (COVID-19) and have inferred the molecular mechanism by which it invades the nervous system. The neurological aspect of the COVID-19 pandemic has been differently interpreted and dealt with in different parts of the world. To review the neurological manifestations and the neurovirulent mechanism by which CoV attacks the human nervous system and to examine different perspectives on this very same topic, the research on PubMed and ScienceDirect is conducted. The mechanisms that CoV enter and attack the nervous system and the subsequent neurologic manifestations have been proposed and now seems quite clear. However, more studies have to be done directly on the effect of COVID-19 on the CNS as well as the PNS.

scholarly journals Neurological manifestations of COVID-19: a clinical approach

2021 ◽  
Author(s):  
Ni Made Susilawathi ◽  
Kumara Tini ◽  
Ida Ayu Sri Wijayanti ◽  
Putu Lohita Rahmawati ◽  
Dewa Putu Wisnu Wardhana ◽  
...  
Keyword(s):  
Nervous System ◽  
World Health ◽  
Critical Conditions ◽  
Clinical Approach ◽  
Vascular Endothelial ◽  
Neurological Manifestations ◽  
Global Pandemic ◽  
The World ◽  
Health Organization ◽  
Human Nervous System

Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by SARS-CoV-2 which attacks the respiratory tract and has been declared a global pandemic by the World Health Organization. The disease has a very wide clinical spectrum which can be manifested as asymptomatic to critical conditions. SARS-CoV-2 shows a neurotropism proven by its identification in the cerebrospinal fluid and brain vascular endothelial. The complete mechanism of how the virus invades the human nervous system is yet to be identified. Thus, every neurologist needs to follow the progressivity of COVID-19 symptoms involving the nervous system.

Neurological Involvement of Patients with COVID-19: Proposed Neuroinvasive Mechanisms and Management

2020 ◽  
Vol 24 (4) ◽  
Author(s):  
Nahid Davoodian ◽  
Maryam Arab Firouzjaei ◽  
Ahmadagha Negahi
Keyword(s):  
Nervous System ◽  
Organ Failure ◽  
Present Article ◽  
Respiratory Symptoms ◽  
Neurological Symptoms ◽  
Neurological Involvement ◽  
The Novel ◽  
Neurological Manifestations ◽  
The World ◽  
Novel Coronavirus

: The novel Coronavirus Disease 2019 (COVID-19) is a highly contagious virus that has caused tremendous chaos in the world. Generally, respiratory symptoms are dominant manifestations in patients with COVID-19. However, the involvement of other organs, such as the nervous system has also been reported, which elucidates the capability of the virus to induce multi-organ failure. In this regard, the presentation of neurological symptoms in infected patients has raised the concern regarding the neuroinvasive potential of COVID-19. As of today, there is emerging evidence that supports the susceptibility of the nervous system to COVID-19. Undoubtedly, the awareness of these findings can result in the timely management and treatment of patients. In the present article, we documented a brief overview of neurological manifestations, possible neuroinvasion mechanisms of COVID-19, and the management of neurological symptoms in infected patients.

scholarly journals COVID-19 Vaccination: From Interesting Agent to the Patient

Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 120
Author(s):  
Anis Daou
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Gastrointestinal Tract ◽  
Circulatory System ◽  
The Novel ◽  
Lead Compound ◽  
Fda Approval ◽  
The World ◽  
The Central Nervous System ◽  
Novel Coronavirus

The vaccination for the novel Coronavirus (COVID-19) is undergoing its final stages of analysis and testing. It is an impressive feat under the circumstances that we are on the verge of a potential breakthrough vaccination. This will help reduce the stress for millions of people around the globe, helping to restore worldwide normalcy. In this review, the analysis looks into how the new branch of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) came into the forefront of the world like a pandemic. This review will break down the details of what COVID-19 is, the viral family it belongs to and its background of how this family of viruses alters bodily functions by attacking vital human respiratory organs, the circulatory system, the central nervous system and the gastrointestinal tract. This review also looks at the process a new drug analogue undergoes, from (i) being a promising lead compound to (ii) being released into the market, from the drug development and discovery stage right through to FDA approval and aftermarket research. This review also addresses viable reasoning as to why the SARS-CoV-2 vaccine may have taken much less time than normal in order for it to be released for use.

Nutritional Deficiencies

2017 ◽  
Author(s):  
Deanna Saylor ◽  
John C. Probasco
Keyword(s):  
Bariatric Surgery ◽  
Developing Countries ◽  
Nervous System ◽  
Nutritional Deficiencies ◽  
Neurologic Manifestations ◽  
Neurological Manifestations ◽  
Biochemical Activity ◽  
Vitamin Deficiencies ◽  
Post Bariatric Surgery ◽  
Developed World

Nutritional deficiencies are estimated to affect at least one third of the world’s population. Although they are most common in developing countries, they are also found in the developed world where they often occur in the setting of alcoholism, eating disorders, post bariatric surgery, and malabsorptive disorders. Neurologic manifestations of vitamin deficiencies are varied, reflecting the diversity of biochemical activity of vitamins throughout the nervous system. Here the neurological manifestations of common vitamin deficiencies are examoned, beginning with a discussion of relevant biochemistry and pathophysiology of each respective vitamin. Several micronutrients are included in the tables within this chapter.

scholarly journals Neurological manifestations of ixodic tick-borne borreliosis associated with chronic opisthorchiasis in the Tomsk Region

2010 ◽  
Vol 9 (4) ◽  
pp. 123-128
Author(s):  
S. A. Pershina ◽  
N. G. Zhukova ◽  
L. V. Lukashova ◽  
I. N. Udintseva
Keyword(s):  
Nervous System ◽  
Comparative Analysis ◽  
Pathological Process ◽  
Acute Stage ◽  
Neurological Manifestations ◽  
Analog Scale ◽  
Cognitive Failures ◽  
Tomsk Region ◽  
Neurological Pathology ◽  
Different Parts

A comparative analysis of neurological manifestations in patients with acute ixodic tick-borne borreliosis (ITB) and patients with ITB associated with chronic opisthorchiasis has been carried out. It has been found that at ITB in the acute phase, nearly all parts of the nervous system are involved in the pathological process. Diseases of central parts of the nervous system were found in 86.7% patients with the monoinfection and in 96.7% patients with ITB associated with chronic opisthorchiasis, diseases of the vegetative part were found in 75.0 and 83.3% patients, and peripheral failures were found in 18.3 and 48.3% patients, respectively. In the structure of neurological pathology of the acute stage of ITB with chronic opisthorchiasis, the prevalence of the combined disease of different parts of the nervous system (93.3%), the more frequent occurrence (96.7%) and higher intensity of headaches (more than 4 points by the visual analog scale), vertigo (76.7%), cognitive failures (35.0%), signs of the vegetative disfunction syndrome (95.0%), and peripheral neuropathy (48.3%) were diagnosed.

scholarly journals Laboratory testing for COVID-19 in suspected human cases and the impact of corona virus pandemic on the global health system

2020 ◽  
Vol 5 (4) ◽  
pp. 498-504
Author(s):  
Debashis Mania ◽  
T.K. Mandal ◽  
A.K. Bera ◽  
Brig. Rajiv Sethi
Keyword(s):  
Laboratory Testing ◽  
Multiple Organ ◽  
Human Beings ◽  
Indian Health ◽  
Corona Virus ◽  
Organ Systems ◽  
The World ◽  
The Impact ◽  
Organ Invasion ◽  
Different Parts

COVID-19, coronavirus (SARS-CoV-2) infection has become pandemic after first appearing in Wuhan, China in December 2019. It destroyed the life of millions of people throughout the different parts of Europe, America, Asia and others in the world. Various groups of scientists throughout the globe have claimed on trialing for the corona vaccine and for finding out suitable medication for the treatment of COVID-19. No vaccine or medicines are successfully reported to short out the issue for saving the valuable life of human beings, till date. The mechanism of SARS-CoV-2 infection and organ invasion are not understood and it creates difficulty in clinical diagnosis and treatment of corona patients. The pathogenic mechanism of SARS-CoV-2 infection is not very much clear and it may invade multiple organ systems of respiratory, digestive and hematological in a confirmed case. The impact of corona virus outbreak on the global and Indian health systems is also reviewed herewith.

scholarly journals Analyzing and Visualizing the Impact of Covid19 on the World

2020 ◽  
pp. 265-268
Keyword(s):  
World Health ◽  
The Novel ◽  
Global Public Health ◽  
Corona Virus ◽  
Johns Hopkins University ◽  
Large Numbers ◽  
The World ◽  
Open Datasets ◽  
Health Organization ◽  
The Impact

The Novel Corona virus is emerging as a Global public health threat. The outbreak initially emerged in Wuhan, China, large numbers of patients were getting sick because of Pneumonia and later it was found that they were nfected with the Novel Corona virus this emphasizes the importance of analyzing the data of this virus and predicting their risks of infecting people all around the globe. In this study, we present an effort to compile and analyze the outbreak information on COVID19 based on the open datasets on 2019 nCoV provided by the Johns Hopkins University, World Health Organization. An exploratory data analysis with visualizations has been made to understand the number of different cases reported (confirmed, death, and re-covered) in the World. Overall, at the outset of an outbreak like this, it is highly important to readily provide information to begin the evaluation necessary to understand the risks and begin containment activities.

scholarly journals Being aware of the neurological manifestations of COVID-19 infection

2021 ◽  
Vol 40 (3) ◽  
pp. 187-189
Author(s):  
Basak Atalay
Keyword(s):  
Respiratory Tract ◽  
Sore Throat ◽  
Strong Evidence ◽  
Initial Presentation ◽  
The Novel ◽  
Neurologic Manifestations ◽  
Neurological Manifestations ◽  
Impaired Consciousness ◽  
Atypical Symptoms ◽  
Novel Coronavirus

The novel coronavirus disease- 2019 (COVID-19) is first reported from China, and unfortunately, no longer restricted, and spreads in all geographies.(1) The main symptoms of COVID-19 infection are respiratory tract related. Infected patients usually have symptoms such as fever, sore throat, and fatigue, and they may have atypical symptoms like headache, seizure, anosmia, stroke, and even impaired consciousness. Strong evidence of an association between COVID-19 infection and neurological manifestations has been reported. Besides, the neurologic manifestations may be the initial presentation of COVID-19 infection.

scholarly journals A Review on Automatic Covid-19 Lung Infection Detection from Different Imaging Techniques

2021 ◽  
Vol 9 (VII) ◽  
pp. 3850-3856
Author(s):  
Sangeeta Singh
Keyword(s):  
World Health Organization ◽  
Virus Disease ◽  
Imaging Techniques ◽  
World Health ◽  
The Novel ◽  
Corona Virus ◽  
The World ◽  
Health Organization ◽  
High Level ◽  
Precision Rate

Corona Virus Disease-2019 commonly known as COVID-19 which has been defined by the Novel Corona Virus. It is a family of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and was first detected during respiratory outbreak. It was first reported to the World Health Organization on December 31, 2019. On January 30, 2020, the World Health Organization declared the COVID-19 eruption a global health emergency. As of 27-May-2021 169,095,283 confirmed cases have been reported in the world and 2, 73, 67, 935 cases in India. It is required to identify the infection with high precision rate but there are lots of deficiency in the diagnosing system that may resulted false alarm rate. Initially it could be detected through throat saliva but now it can also be identified thought the impairment in lungs from computerized tomographical imaging technique. This paper reviewed various researches over COVID-19 diagnosis approach as well as the syndrome in respiratory organs. There are so many imaging techniques through which lungs impairments can be detected that may diagnose COVID-19 with high level of accuracy. CT scan image is the best alternative for diagnosing COVID-19.

scholarly journals COVID-19: The Pandemic Situation in the Context of India

2021 ◽  
pp. 456-463
Author(s):  
Daksh Hardaswani
Keyword(s):  
Virus Disease ◽  
The Novel ◽  
Physical And Mental Health ◽  
Health Crisis ◽  
Animal Virus ◽  
Therapeutic Drugs ◽  
Corona Virus ◽  
Hand Wash ◽  
The World ◽  
Financial Impacts

The novel corona virus disease (COVID-19) is a pandemic due to the global health crisis it has created in the world and greatest challenges that it has introduced in this 21ST century. COVID-19 is the the 5th pandemic which was first reported in Wuhan, China and gradually spread into the other parts of the world. This virus is a spillover of an animal virus and then also adapted the ability of transferring human to human. The virus is highly contagious due to rapid spread and constantly evolves in the human population.  COVID-19 pandemic is a lot more than just a health emergency, but it is also socio-economic because people are losing jobs and income. The COVID-19 disease affects physical and mental health due to isolation. Moreover, more and more countries are affecting the cases of COVID-19 which are rising very rapidly day by day. Therefore, every country needs to several actions which accelerates their safety health, balance between the protection of health, prevent economic and social disruption due to this pandemic. In the spirit of the solidarity, we all need to be contributing our self to protect this situation. However, every country is equally responsible for determining the measures to prevent or decrease the viral transmission. Government authorizes also trying to act for reduce disease’s trajectory and they focus on develop the vaccination and therapeutic drugs.  Aim: To find causes, symptoms, awareness, Prevention, and treatment of COVID-19. Conclusion: The world is going by the critical situation and that is COVID-19 pandemic which is originated due to corona virus. Shortness of breath, fever and dry cough are most common symptoms of the novel corona virus. COVID-19 is highly contagious, so we must keep safe distance from other people and wear a mast hand wash our hands frequently. As it were together can we overcome the interwoven wellbeing and social and financial impacts of the widespread and anticipate its acceleration into an extended compassionate and nourishment security catastrophe, with the potential misfortune of as of now accomplished advancement picks up. 

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