Use of water-soluble polysaccharides from mango (Mangifera indica L.) fruits as alternative source of mutanase inductors

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
A Wiater ◽  
K Próchniak ◽  
M Janczarek ◽  
M Pleszczyńska ◽  
M Tomczyk ◽  
...  
2021 ◽  
Vol 1 (1) ◽  
pp. 1-8
Author(s):  
Andini Andini ◽  
Cindy Fernanda Putri

Mango peel (Mangfera indica L.) has many pharmacological effects as a traditional medicine. Therefore, standardization of mango peel simplisia needs to be done as a preparation of phytopharmaca raw material. This research aimed to obtain standardization of mango peel simplisia include specific and non-specific parameter. The research procedures include plant determination, simplisia preparation as well as specific standardization test (includes organoleptic, water-soluble compound concentration, and ethanol solution compound concentration) and nonspecific standardization test (includes moisture content, dried shrinkage, total ash content and acid insoluble ash content). The specific organoleptic parameters of dried mango peel simplisia have a distinctive sweet aroma, bitter taste, and brownish yellow colour. Water-soluble and ethanol-soluble concentrations are 22,36% ± 1,17% and 9,56% ± 0,07%. Moisture content is 9,09% ± 1,44%. Dried shrinkage rate is 0,19% ± 0,04%. Total ash and acid insoluble ash contents are 4,11% ± 0,10% and 0,14% ± 0,03%. The mango peel simplisia has met the quality standard of the raw material.


2020 ◽  
Vol p4 (05) ◽  
pp. 2394-2400
Author(s):  
Pooja Dogra ◽  
A. Rama Murthy ◽  
Sumit Nathani

Introduction: Mangifera Indica Linn., Anacardiaceae family, is a large evergreen tree of tropical and sub-tropical regions of the world. Mango kernel can be used as a potential source for functional food ingredi-ents, animal feeds, antimicrobial compounds and cosmetic due to its high quality of fat and protein as well as high levels of natural antioxidants. Aim: The aim of the present study was to evaluate the physicochemical and phytochemical analysis of Mangifera Indica Linn. Methods Aamra Kernel were collected, cleaned, dried and powdered. Aqueous and alcoholic extracts of Aamra kernel were analyzed for physicochemical and phytochemical constituents. The study was conduct-ed as per the guidelines of Ayurvedic pharmacopeia of India. Results: The result of physicochemical parameters (moisture content: 10.2%, total ash: 2.12%, acid insolu-ble ash: 0.3%, water soluble ash: 1.42%, aqueous extractive value: 14.67% and alcoholic extractive value 12.98%). The phytochemical studies revealed the presence of active constituents, carbohydrates, amino acid, steroids, proteins, saponins, alkaloids, glycosides, tannins in aqueous and alcoholic extracts. Conclusion: All studies standardization parameters like physicochemical and phytochemical screening pa-rameters provide the knowledge in the identification, authentication of kernel of Mangifera Indica Linn. Hence it is concluded that this drug supposed to be great beneficial and boon for our society.


Weed Science ◽  
1969 ◽  
Vol 17 (2) ◽  
pp. 154-157 ◽  
Author(s):  
R. W. Bovey ◽  
J. D. Diaz-Colon

Studies were conducted to determine the effect of simulated rainfall on the phytotoxicity of several herbicides. Oil soluble herbicides 4,6-dinitro-o-sec-butylphenol (DNBP), pentachlorophenol (PCP), a 1:1 mixture of the butyl esters of 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid (2,4-D: 2,4,5-T), and a 2:2:1 mixture of the isooctyl esters of 2,4–13:2,4,5-T: 4-amino-3,5,6-trichloropicolinic acid (picloram) (hereinafter referred to as M-3140), usually were less affected by artificial rainfall than were water soluble 1,1'-dimethyl-4,4'-bipyridinium salt (paraquat), dimethylarsinic acid (cacodylic acid), and cis-2,3,5,5,5-pentachloro-4-ketopentenoic acid (hereinafter referred to as AP-20), on guava (Psidium guajava L.) and mango (Mangifera indica L.). Washing reduced the activity of some oil and water-soluble herbicides on sorghum (Sorghum bicolor (L.) Moench, var. Combine Kafir-60) and dioscorea (Dioscorea composita Hemsl). As herbicide rates were increased, washing reduced the phytotoxicity of paraquat and 2,4-D:2,4,5-T less on mango and guava. Artificial rainfall applied as a mist spray at different intervals had no effect on the phytotoxicity of paraquat; it reduced the activity of cacodylic acid and increased the effectiveness of AP-20 on mango.


2020 ◽  
Vol 138 ◽  
pp. 109719
Author(s):  
Omar Patiño-Rodríguez ◽  
Luis A. Bello-Pérez ◽  
Edith Agama-Acevedo ◽  
Glenda Pacheco-Vargas

2021 ◽  
Vol 6 (48) ◽  
pp. 2-2
Author(s):  
Olga Kameneva ◽  
Oksana Kibalnik ◽  
Irina Efremova ◽  
Dmitry Semin ◽  
Yuri Kalinin

The ability of sugar sorghum plants to accumulate 18-24% of water-soluble sugars in the juice of stems expands the potential of the crop as a raw material for the production of not only feed (green feed, silage), but also in various areas of the processing industry for food (glucose-fructose syrup, sorghum honey) and technical purposes (bioethanol, biofuels). The brief review presents data on the origin; biological features of sorghum; on the fractional composition of water-soluble sugars; on global trends in the use of renewable energy sources. The advantage of growing Sorghum saccharatum as a sugar carrier in regions with insufficient moisture is reflected. Keywords: SUGAR SORGHUM, WATER-SOLUBLE SUGARS, FRUCTOSE, GLUCOSE, SUCROSE, SUGAR SYRUP, BIOETHANOL, BIOFUEL


2020 ◽  
Vol 42 ◽  
pp. e52115
Author(s):  
Fabiana Guillen Moreira Gasparin ◽  
Marcio de Barros ◽  
Gabriela Alves Macedo

Esterases are enzymes that present good potential for industrial applications since they catalyze the formation or cleavage of ester bonds in water-soluble substrates, and sorghum seeds can represent an alternative source of this enzyme. The extraction of esterase from sorghum seeds is an economical alternative to obtain an enzyme of great interest. Esterases may improve the quality or accelerate the maturation of cheeses, cured bacon and fermented sausages and may also resolve racemic mixtures. Recently, seed esterases have been the focus of much attention as biocatalysts. In some cases, these enzymes present advantages over animal and microbial lipases due to some quite interesting features such as specificity and low cost, being a great alternative for their commercial exploitation as industrial enzymes The esterase studied here was extracted from sorghum seeds and some of its biochemical properties determined using synthetic substrates (p-nitrophenyl butyrate, caprylate, laurate and palmitate). The enzyme presented optimum activity at pH 8.0 and was stable in all the pH ranges studied. The optimum temperature for its activity was 40ºC but it showed low stability at this temperature (40% relative activity). The values derived for Km and Vmax were 0.67mM and 125 U.mg-1, respectively, obtained using p-nitrophenyl butyrate as the substrate. The enzyme showed an increase in activity when K2HPO4 was added to the reaction medium, but the ions Mn2+, CO+, Hg+ and Fe2+ strongly inhibited the enzyme activity. This enzyme showed a preference for the hydrolysis of short chain fatty acids. The characteristics of sorghum esterase are very similar to those of the microbial esterases used in detergent processing.


HortScience ◽  
2012 ◽  
Vol 47 (10) ◽  
pp. 1466-1471 ◽  
Author(s):  
Zhengke Zhang ◽  
Zhaoyin Gao ◽  
Min Li ◽  
Meijiao Hu ◽  
Hui Gao ◽  
...  

‘Tainong 1’ mango fruit were treated with hot water for 10 minutes at 55 °C and then stored at 5 °C for 3 weeks. After removal from low-temperature storage, the effects of hot water treatment (HWT) on chilling injury (CI), ripening and cell wall metabolism during storage (20 °C, 5 days) were investigated. HWT reduced the CI development of the fruit as manifested by firmer texture, external browning, and fungal lesions. A more rapid ripening process, as indicated by changes in firmness, respiration rate, and ethylene production, occurred in heated fruit after exposure to low temperature as compared with non-heated fruit. At the same time, the cell wall components in heated fruit contained more water-soluble pectin and less 1,2-cyclohexylenedinitrilotetraactic acid (CDTA)-soluble pectin than those in non-heated fruit. HWT also maintained higher polygalacturonase [enzyme classification (EC) 3.2.1.15] and β-galactosidase (EC 3.2.1.23) activities as well as lower pectin methylesterase (EC 3.1.1.11) activity. In general, the changes of ripening and cell wall metabolism parameters in the heated fruit after low-temperature storage exhibited a comparable pattern to that of non-cold-stored fruit.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Md Tausif Alam ◽  
Nayyar Parvez ◽  
Pramod Kumar Sharma

Oral route is the most preferred route for administration of different drugs because it is regarded as safest, most convenient, and economical route. Fast disintegrating tablets are very popular nowadays as they get dissolved or facilely disintegrated in mouth within few seconds of administration without the need of water. The disadvantages of conventional dosage form, especially dysphagia (arduousness in swallowing), in pediatric and geriatric patients have been overcome by fast dissolving tablets. Natural materials have advantages over synthetic ones since they are chemically inert, non-toxic, less expensive, biodegradable and widely available. Natural polymers like locust bean gum, banana powder, mango peel pectin, Mangifera indica gum, and Hibiscus rosa-sinenses mucilage ameliorate the properties of tablet and utilized as binder, diluent, and superdisintegrants increase the solubility of poorly water soluble drug, decrease the disintegration time, and provide nutritional supplement. Natural polymers are obtained from the natural origin and they are cost efficacious, nontoxic, biodegradable, eco-friendly, devoid of any side effect, renewable, and provide nutritional supplement. It is proved from the studies that natural polymers are more safe and efficacious than the synthetic polymers. The aim of the present article is to study the FDA-approved natural polymers utilized in fast dissolving tablets.


Author(s):  
K. Krishnananda Kamath ◽  
A. Shabaraya

Herbal medicine have become an item of global importance both has medicinal and economical value. Plants used for medicinal purposes long before recorded history. Many plant species have been proved to have antibacterial activity. Thus, the main objective of the study was to formulate and evaluate a poly-herbal semisolid dosage forms using ethanolic extracts of frontal leaves of T. grandis, M. indica and A. occidentale. Formulations were evaluated for its physicochemical properties like color, consistency, pH, spreadability, extrudability and the results were found satisfactory. Antibacterial activity of formulations was studied against S. aureus, E. coli and P. aeruginosa by agar well diffusion method. (E. coli, P. aeruginosa) bacteria. The order of activity was as follows: Water Soluble bases > Gel Bases > Hydrocarbon Bases. The zones of inhibition of poly herbal formulations were in between 23-28 mm which can be comparable with standard formulation 24-29 mm. Activity of the formulations may be due to the presence of alkaloids, flavanoids, phenols and tannins in the extracts. The formulations were found to be very efficacious in all the parameters.


Author(s):  
J. G. Robertson ◽  
D. F. Parsons

The extraction of lipids from tissues during fixation and embedding for electron microscopy is widely recognized as a source of possible artifact, especially at the membrane level of cell organization. Lipid extraction is also a major disadvantage in electron microscope autoradiography of radioactive lipids, as in studies of the uptake of radioactive fatty acids by intestinal slices. Retention of lipids by fixation with osmium tetroxide is generally limited to glycolipids, phospholipids and highly unsaturated neutral lipids. Saturated neutral lipids and sterols tend to be easily extracted by organic dehydrating reagents prior to embedding. Retention of the more saturated lipids in embedded tissue might be achieved by developing new cross-linking reagents, by the use of highly water soluble embedding materials or by working at very low temperatures.


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