Evaluation of the Stability of the Subjects with Anterior Cruciate Injuries Reconstruction

AbstractAnterior cruciate ligament (ACL) is the most frequently injured ligament in the knee and is often injured during sport-related activities. ACL injuries influence the abilities of the subjects during standing and walking. Although early surgical intervention is preferred treatment for the majority of knee surgeons, the effect of this approach on postural stability of patients is not fully understood. Therefore, the aim of this study was to determine the difference between stability of ACL-reconstructed subjects before and after surgery. A group of 15 consecutive ACL injured patients participated in this study. Postural stability of the patients was evaluated 1 week before and 6 months after surgery (ACL reconstruction with hamstring autograft). A Kistler force plate was used to evaluate center of pressure (COP) sway during quiet standing. The mean values of the COP parameters were obtained in pre and postsurgery conditions. Paired sample t-test was used to evaluate the difference between the stability parameters of the two conditions. The significant point was set at 0.05. The mean value of path length of COP velocity in mediolateral (ML) direction was 1,485.57 ± 479.42 mm and 2,641.33 ± 996.26 mm before and after surgery, respectively (p-value = 0.01). Although the mean value of COP velocity in anteroposterior and ML directions increased after surgery, the difference was only significant for velocity in ML direction (p-value = 0.049). The results of this study showed that the standing stability of those with ACL reconstruction decreased significantly after ACL reconstruction, which may be due to the effects of the surgery on sensory mechanism of ACL and inability of patients to return to their previous deep sense perception and knee proprioception.

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Evaluation the influence of core stability exercise on standing stability of hemiplegic cerebral palsy

10.21203/rs.2.23490/v1 ◽

2020 ◽

Author(s):

mohammad Karimi

Keyword(s):

Cerebral Palsy ◽

Approximate Entropy ◽

Normal Subjects ◽

Mean Value ◽

Core Stability ◽

Quiet Standing ◽

P Value ◽

Before And After ◽

The Mean ◽

The Stability

Abstract Background: Cerebral palsy (CP) is one of the most common neurological disorders influences the abilities of the subjects to stand and walk. Various kinds of exercise are recommended to improve the stability of CP subjects during quiet standing. However, there is no evidence regarding the effects of core stability exercise on stability of CP subjects. Therefore, the aim of this research was to determine the efficiency of this exercise on stability of CP subjects.Method: Two group of normal and CP children were recruited in this study (10 subjects). The stability of the subjects was determined by use of a Kistler forceplate. The stability of the subjects was measured by Approximate entropy (ApEn) based on COP sways. The dynamic stability was evaluated by Berge balance scale. Ashworth scale was used to determine the spasticity of lower limb muscles groups. Results: The mean value of ApEn of CP patients in the anteroposterior and mediolateral directions were 0.465±0.11 and 0.426±0.99, respectively compared to 1.02±0.11 and 0.426±0.099 for normal subjects. There was a significant increase in ApEn of CP subjects before and after exercise (p-value<0.05). The mean value of Berge scale was 46.2±5.77 and 51.87±3.9 before and after exercise, respectively.Conclusion: As lower value of ApEn associated with decrease in complexity, higher rigidity and unstability, it can be concluded that CP subjects were unstable than normal subjects. Use of core stability exercise improves complexity of the system and improves the stability of the subjects due to its effect on muscular spasm.

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PERBANDINGAN STATUS KEBERSIHAN GIGI DAN MULUTPADA ANAK BERKEBUTUHAN KHUSUS SLB-B DAN SLB-C KOTA TOMOHON

e-GIGI ◽

10.35790/eg.3.2.2015.9605 ◽

2015 ◽

Vol 3 (2) ◽

Author(s):

Vivie Indahwati ◽

Max F. J. Mantik ◽

Paulina N. Gunawan

Keyword(s):

Oral Hygiene ◽

Mean Value ◽

T Test ◽

P Value ◽

Special Needs Children ◽

Normal Children ◽

Children With Disability ◽

The Mean ◽

The Difference ◽

Better Than

Abstract: Special need children is children with disability mental, physical, and emotion which different with the normal children, thus their more needed parents help in keeping hygene especially oral hygene. Every disability they have influenced the behaviour of special need children in keeping their oral hygiene. This study aimed to obtain the difference of oral hygiene between special needs children in SLB-B and SLB-C in Tomohon.This was a descriptive analytical study. Samples were obtained by total sampling method. This study was conducted at SLB-B GMIM Damai Tomohon and SLB-C Katolik Santa Anna Tomohon. There were 101 children in this study. The results of independent t test showed that there were significant differences between the mean value of OHI-S status at SLB-B (1.86) and the mean value OHI-S status at SLB-B ( 2.50) with a P value of <0,05. Conclusion: Oral hygiene of SLB-B children was significantly better than of SLB-C children.Keywords: oral hygiene, special need childrenAbstrak: Anak berkebutuhan khusus merupakan anak yang memiliki keterbatasan mental, fisik dan emosi yang berbeda dengan anak normal, sehingga mereka memerlukan bantuan dalam menjaga kebersihan diri khusunya kebersihan gigi dan mulut. Perbedaan keterbatasan yang mereka miliki, memengaruhi perilaku anak berkebutuhan khusus dalam menjaga kebersihan gigi dan mulut. Penelitian ini bertujuan untuk melihat bagaimana perbedaan status kebersihan gigi dan mulut pada anak berkebutuhan khusus di SLB-B dan SLB-C kota Tomohon, Jenis penelitian yang digunakan adalah deskriptif analitik. Pengambilan sampel penelitian ini secara total sampling. Pengambilan data dilaksanakan di SLB-B GMIM Damai Tomohon dan SLB-C Katolik Santa Anna Tomohon. Jumlah anak dalam penelitian sebanyak 101 anak. Hasil penelitian diolah dengan uji statistik t tidak berpasangan (independent t test).Dari uji statistik diperoleh bahwa terdapat perbedaan rerata yang bermakna, antara status OHI-S SLB-B dengan nilai rata-rata 1,86 dibandingkan status OHI-S SLB-C dengan nilai rata-rata 2,50 dan nilai p<0,05. Simpulan: Rerata status kebersihan gigi dan mulut SLB-B lebih baik secara bermakna dibandingkan dengan SLB-C.Kata kunci: kebersihan gigi dan mulut, anak berkebutuhan khusus

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Investigation of Olfactory Function Following Septorhinoplasty in Iranian Population by Rapid Smell Test (RST)

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2019/v31i630369 ◽

2020 ◽

pp. 1-6

Author(s):

Amir Yarahmadi ◽

Kamran Kamrava ◽

Ali Shafee ◽

Maryam Milanifard ◽

Mohammad Aghajanpour ◽

...

Keyword(s):

Social Sciences ◽

Olfactory Function ◽

P Value ◽

Clinical Tool ◽

Smell Test ◽

Before And After ◽

The Mean ◽

The Difference ◽

Smell Identification

Introduction: All surgical procedures on nose affect the olfactory function to some extent. There are different viewpoints about olfactory function after septorhinoplasty. We aim to investigate smell perception changes in patients following septorhinoplasty. In this study the use of Rapid Smell Test (RST) as a fast and reliable clinical tool was investigated. Methods: A prospective cohort study was done in Rasool Akram teaching hospital in 2018 and 2019. Group of 74 septorhinoplasty candidates aged over 18 was selected by convenience. Persian Smell Identification Test (PSIT) and rapid smell test (RST) was obtained from patients before surgery and one month after, if needed three months after and six months after. In addition for patients with dysfunction in any of follow up periods (one month, 3 months and 6 months after surgery) smell magnitude test (SMT) was used. All data were analyzed using Statistical Package for Social Sciences, version 24.0 (IBM SPSS Statistics Inc., Chicago, IL, USA). Results: Out of 74 patients participating in this study 67 were female. Mean age of 25.68±5.18 years was recorded for participants. All patients before surgery had PSIT score more than 19 and the mean PSIT score before operation was 22.63±1.39. Also all patients scored 5 out of 5 in RST before surgery. Mean PSIT score one month after surgery decreased to 22.21±2.20 but still 93 percent (69 patients) of participants were in range for normal olfactory function. We recorded this to be significant (p value = 0.044). RST after one month showed the same results. The difference between RST before and after surgery was also significant (p value = 0.024). For those 5 patients with abnormal olfactory function PSIT and RST were done 3 months after operation which determines normal olfactory function for all of them. As well as PSIT, RST also shows the same results and five participants recorded 5 out of 5 three months after surgery. Conclusion: This study showed changes in olfactory function after septorhinoplasty will resolve at most 3 months after surgery and it is safe to say there is no effect on olfactory function three months after operation. Also we demonstrated that RST can be a fast and reliable tool for assessing patients’ olfactory function in clinical setting.

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AB0495 BIOMECHANICAL STRESS IN THE CONTEXT OF COMPETITIVE SPORTS TRAINING TRIGGERS ENTHESITIS

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.1793 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 1275.1-1275

Author(s):

D. Simon ◽

A. Kleyer ◽

S. Bayat ◽

J. Knitza ◽

L. Valor ◽

...

Keyword(s):

Psoriatic Arthritis ◽

Mechanical Stress ◽

Power Doppler ◽

Mean Value ◽

Mixed Effects ◽

P Value ◽

Biomechanical Stress ◽

Score Difference ◽

Before And After ◽

The Mean

Background:Preclinical models have indicated that biomechanical stress can trigger entheseal inflammation (1). Furthermore, enthesitis is a hallmark of psoriatic arthritis (PsA) and spondyloarthritis (SpA), suggesting that mechanoinflammation is an important step in their pathogenesis (2). However, the relation between mechanical stress and enthesitis in humans is poorly investigated. Competitive badminton is a demanding stop-and-go sport that strains entheseal sites in particular and provides an opportunity to assess the impact of physical activity on the development of an instant inflammatory response in the entheses.Objectives:To evaluate the influence of mechanical stress on the development of immediate enthesitis.Methods:BEAT (Badminton Enthesitis Arthrosonography Study) is an interventional study that assessed entheses in competitive badminton players before and immediately after a 60-minute intensive training session by ultrasound. Power Doppler (PD) signal and Gray-Scale (GS) changes were evaluated at the insertions sites of both Achilles tendon, patellar tendons and lateral humeral epicondyles and quantified using a validated scoring system (3). Pre- and post-training scores were compared using linear mixed-effects models. We used interaction terms to assess possible differential effects on patellar, elbow and Achilles entheses.Results:Thirty-two badminton players (22 men, 10 women) with an average age of 31.1±13.0 years were included (Table 1). On average, they had been playing badminton for 16.2±10.1 years. 192 entheseal sites were examined twice. The respective empirical total scores for PD examination were 0.1 (0.3) before and 0.5 (0.9) after training (Figure 1). Mean total GS scores were 2.9 (2.5) and 3.1 (2.5) before and after training, respectively. The mean total PD score difference of 0.4 between pre- and post -training was significant with a p value of 0.0014, whereas the p value for the mean total GS score difference of 0.2 was 0.63. Overall, seven participants (22%) showed an increased empirical total PD score. A mixed-effects model showed a significant increase of PD scores after training, with a mean increase per site of 0.06 (95%CI 0.01 to 0.12, p=0.017).Table 1.Baseline characteristicsDemographic characteristicsN, total32Females, N (%)10 (31.3)Age, years (mean ± SD)36.1 ± 13.0Height, cm (mean value ± SD)178.6 ± 9.9Body weight, kg (mean value ± SD)74.7 ± 13.5Smoking, N (%)11 (34.4)Alcohol, N (%)24 (75.0)Concomitant DiseasesInflammatory bowel disease, N (%)0Psoriasis, N (%) 0Uveitis, N (%)0Diabetes mellitus, N (%)0Hypertension, N (%)2 (6.3)Sports historyYears Badminton (mean ± SD)16.2 ± 10.1Figure 1.Ultrasound scores before and after training Figure 1. A Spaghetti plots depicting inividual Gray-Scale and Power Doppler ultrasound scores before and after trainingConclusion:Mechanical stress leads to rapid inflammatory responses in the entheseal structures of humans. These data support the concept of mechanoinflammation in diseases associated with enthesitis. However, while such responses may be self-contained in healthy subjects, they may be prolonged and more pronounced in certain risk groups, such as patients with PsA or SpA.References:[1]Cambré I, et al. Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis. Nature Communications. 2018; 9:4613.[2]Schett G, et al. Enthesitis: from pathophysiology to treatment. Nat Rev Rheumatol. 2017; 13:731-741.[3]Balint PV, et al. Reliability of a consensus-based ultrasound definition and scoring for enthesitis in spondyloarthritis and psoriatic arthritis: an OMERACT US initiative. Annals of the Rheumatic Diseases. 2018; 77:1730.Disclosure of Interests:David Simon: None declared., Arnd Kleyer: None declared., Sara Bayat: None declared., Johannes Knitza: None declared., Larissa Valor: None declared., Marina Schweiger: None declared., Georg Schett: None declared., Koray Tascilar: None declared., Axel Hueber Grant/research support from: Novartis Research Grant.

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Effect of the Use Lethal Ovitrap to Population Aedes sp

Medical Science & Healthcare Practice ◽

10.22158/mshp.v1n1p20 ◽

2017 ◽

Vol 1 (1) ◽

pp. 20

Author(s):

Tri Ramadhani ◽

Bondan Fajar Wahyudi

Keyword(s):

Population Control ◽

Total Sample ◽

Control Group ◽

P Value ◽

Before And After ◽

Quasi Experimental ◽

The Mean ◽

The Difference ◽

And Control ◽

Experimental Group

Dengue vector control has been done in various ways, however, has not been able to obtain optimal results. Ovirap use to determine the presence of Aedes sp in a region is often done, but the application of lethal ovitrap for population control Aedes sp still rarely done. This study was aimed to assess the effect of LO applications on populations of Aedes sp. This research includes quasi experimental design with a pretest-posttest control group without randomization. Research sites in dengue in endemic areas in Banyumas district, with a total sample of 100 homes in each treatment and control areas. Insecticides used on ovistrip is cypermethrin at a dose of 12.5 mg ai/strip. Populations of Aedes sp measured each week for three weeks prior to the intervention and twelve weeks during the intervention. The mean density of Aedes sp compared before and after intervention and between treatment and control areas. The study showed the difference of mosquito densities before and after the intervention in the experimental group was 0,07 ( p-value 0.044), whereas the control group was 0.037 (p-value 0.341). LO use with the addition of insecticide active ingredient cypermetrin on ovistrip impact on the decline density of Aedes sp.

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A Counseling on Complementary Food to Mothers of Infants Aged 6--24 Months at A Community Clinic in Sukmajaya

MITRA Jurnal Pemberdayaan Masyarakat ◽

10.25170/mitra.v3i1.496 ◽

2019 ◽

Vol 3 (1) ◽

pp. 11-20

Author(s):

Avliya Quratul Marjan ◽

A’immatul Fauziyah ◽

M. Ikhsan Amar

Keyword(s):

Breast Milk ◽

Mean Value ◽

Complementary Food ◽

Average Score ◽

P Value ◽

Before And After ◽

Post Test ◽

Service Activity ◽

Nutritional Needs ◽

The Difference

MPASI, complementary food to breast milk, is food or drink containing nutrients, given to babies or infants aged 6-24 months, and given in stages according to the age and digestive capacity of the babies or infants to meet their nutritional needs other than breast milk. The objective of the activity was to improve the mothers’ knowledge of correct and good complementary food for their under-five-year-old infants in Sukmajaya, Depok 2018 and to determine the differences of these mothers’ knowledge about how to process and use ingredients for the complementary food before and after counseling. The method of this community service activity was through pre- and post-test designs. The results showed that the average score of mothers; knowledge before the counseling was 73.00 and after the counseling 79.43. The difference in the mean value between the first and second measurements was 6.43 and the results of the statistical test show the value of P value <0.05. Therefore, it can be concluded that there were significant differences between the pre-test (before counseling) and post-test (after counseling) scores. Based on the results of data processing and analysis, it was found that 66.66% of respondents experienced improving knowledge of complementary food, although the number was still below the target of 70%.

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MO607THE EFFECT OF VITAMINE E ON OXIDATIVE STRESS AND CARDIOVASCULAR COMPLICATIONS IN HEMODIALYSIS PATIENTS

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfab089.0020 ◽

2021 ◽

Vol 36 (Supplement_1) ◽

Author(s):

Leila Azouaou toualbi ◽

Medina Arab ◽

Chahine Toualbi ◽

Khelfi Abderrezak ◽

Henni Chader ◽

...

Keyword(s):

Oxidative Stress ◽

Nitrogen Monoxide ◽

Cardiovascular Complications ◽

Hemodialysis Patients ◽

Protein Product ◽

Mean Value ◽

P Value ◽

Mean Values ◽

The Mean ◽

The Difference

Abstract Background and Aims Oxidative stress represents a risk factor for cardiovascular complications . The aim of the work is to evaluate the effectiveness of vitamin E on cardiovascular complications in hemodialysis patients. Method a study including 420 patients on hemodialysis and 360 controls. Treatment with Vit E at a rate of 300 mg / day for 2 years. All patients benefited from a blood sample of oxidative stress markers as well as paraclinical explorations in search of cardiovascular complications. Results The study grouped together 780 cases. We find that there is a significant relationship between cardiovascular complications and Advanced Oxidation Protein Product (AOPP), Low Density Oxidized Lipoprotein (LDLox), Malondialdehydes (MDA) and Gluthations), we did not find any correlation with nitrogen monoxide (NO) and myeloperoxidases (MPO) .Concerning gluthations (IU / ml ) we observe that the mean values clearly increased after treatment (P-value <0.05) . The mean value of MDA µmol / l significantly decreased after treatment .we note that the cardiovascular complications have decreased (11.03% versus 16.04%) with the decrease in certain markers of oxidative stress. (p > 0.05) Conclusion Regarding cardiovascular complications, we have certainly noticed a drop in their frequency after treatment with vit E without the difference being significant.

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Airway Clearance in Bronchiectasis: A Randomized Control Trial of N-Acetylcysteine with 3% hypertonic saline

Journal of Islamabad Medical & Dental College ◽

10.35787/jimdc.v8i3.389 ◽

2019 ◽

Vol 8 (3) ◽

pp. 146-150 ◽

Cited By ~ 1

Author(s):

Muhammad Imran Shehzad ◽

Muhammad Atiq Ul Mannan ◽

Masood Alam ◽

Abdul Rauf ◽

Muhammad Imran Sharif

Keyword(s):

Acute Exacerbation ◽

Hypertonic Saline ◽

Control Group ◽

P Value ◽

Airway Clearance ◽

Before And After ◽

Group A ◽

The Mean ◽

The Difference ◽

Group B

Background: N-Acetylcysteine and 3% hypertonic saline are being used effectively for sputum clearance in chronic cases of bronchiectasis for quite some time. However, their use in acute condition of the disease seems to be underexplored. The objective of our study is to compare the role of nebulized N-acetylcysteine and 3% hypertonic saline in clearing the airway in patients with acute exacerbation of bronchiectasis. Material and Methods: A total of 136 confirmed cases of bronchiectasis were enrolled in this study. This randomized controlled trial was done in chest ward of Nishtar Hospital Multan from January 2015 to March 2017. Sampling was done by non-probability consecutive sampling and patients were divided into two groups A and B by lottery method. Verbal informed consent was taken from all participants. Group A participants received nebulization of N acetylcysteine mixed in normal saline for ten minutes, while group B participants were nebulized with 10ml of 3% hypertonic saline for ten minutes. Group B was active control group in the study. Data was collected on pre-designed Proforma, and analyzed by SPSS version 22. Numerical variables such as saturation, weight of sputum, age and blood pressure was analyzed by using t test. These were considered significant if the p value was equal or less than 0 .05. For qualitative variables chi square test was applied. Results: The mean O2 saturation of Group A, before and after treatment, was 92.11±3.07% and 94.47±2.18%, respectively. The difference was statistically significant (p value =0.001). The sputum weight of Group A, before and after treatment, was 2.63±2.39 g and 7.41±1.38 g, respectively. The difference was statistically significant (p value =0.001). The frequency of rhonchi of Group A, before and after treatment, was 52% and 76%, respectively. The difference was statistically significant (p value =0.003). While, for Group B, the mean O2 saturation, before and after treatment, was 92.36±3.13% and 93.49±2.27%, respectively. The difference was statistically significant (p value =0.012). The sputum weight, before and after treatment, was 3.11±2.01 g and 5.56±1.02 g, respectively. The frequency of rhonchi, before and after treatment, was 45% and 74% respectively. Again, the difference was statistically significant. Conclusion: Both nebulized N-acetylcysteine and 3% hypertonic saline cause airway clearance by enhancing sputum expectoration in patients with acute exacerbation of bronchiectasis equally. Both these agents also improve oxygen saturation in acute exacerbation of bronchiectasis significantly.

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Perbandingan Metode Brainstorming dan Metode Buzz Group dalam Pemberian KIE Kesehatan Reproduksi di Posyandu Remaja Puskesmas Aur Duri Kota Jambi

Jurnal Akademika Baiturrahim Jambi ◽

10.36565/jab.v10i1.295 ◽

2021 ◽

Vol 10 (1) ◽

pp. 163

Author(s):

Ruwayda Ruwayda ◽

Netti Herawati

Keyword(s):

Reproductive Health ◽

Sampling Technique ◽

Bivariate Analysis ◽

Group Method ◽

Control Group ◽

P Value ◽

Control Group Design ◽

Before And After ◽

The Mean ◽

The Difference

This study aims to analyze the effectiveness of the Brainstorming method and the Buzz Group method in providing IEC for reproductive health at the AurDuri Youth Health Center Posyandu in Jambi City in 2019. This research is a quasi-experimental study using a pretest and posttest design with control group design. The population is all adolescents who visit the posyandu as many as 60 people. Samples were taken using a total sampling technique of 30 treatment groups given the Brainstorming method and 30 people received the Buzz Group method. The research instrument was a questionnaire. Data analysis was carried out univariately to determine the frequency distribution, then bivariate analysis using the dependent t-test to see differences in knowledge before and after giving the brainstorming method and the Buzz Group method. The results showed that there was a difference in the mean increase in respondents' knowledge before and after using the brainstorming method with a mean difference of 1.233 and the difference in knowledge before and after using the buzz group method, namely 3.133. While the results of the analysis of differences in knowledge using the brainstorming method and the buzz group with a p value of 0.000, the difference in the mean value of 2.689 means that the buzz group method is more effective in increasing adolescent knowledge about reproductive health than the brainstorming method. It is suggested that the puskesmas should provide guidance to youth posyandu using a variety of varied methods such as buzz groups in providing IEC for reproductive health

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A prospective study of clinicoepidemiology, metabolic and hormonal profile of women with hirsutism in Konaseema region of Andhra Pradesh

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20213854 ◽

2021 ◽

Vol 10 (10) ◽

pp. 3875

Author(s):

M. Smitha

Keyword(s):

Insulin Resistance ◽

Cushing Syndrome ◽

Mean Value ◽

P Value ◽

Hormonal Profile ◽

Number Of Patients ◽

Menstrual Irregularities ◽

Before And After ◽

The Mean ◽

A Prospective Study

Background: Hirsutism is defined as presence of excess coarse hairs appear in male pattern in women.There is various aetiology of hirsutism like Idiopathic hirsutism, PCOS, androgen secreting ovarian tumours, menopause, CAH, Cushing’s syndrome, drugs which increases testosterone level, insulin resistance and tumour secreting androgen. We have designed present study with an aim to study the clinicoepidemiology, metabolic and hormonal profile of women with hirsutism in Konaseema region of Andhra Pradesh.Methods: All patients with hirsutism attending gynaecology outpatient department were selected for study based on inclusion and exclusion criteria. After that patient were examined clinically, BMI was calculated for each patient. Patients were clinically evaluated for signs of excess androgen secretion, Cushing syndrome, metabolic syndrome and hyperprolactinemia. Modified Ferriman-Gallwey scoring system was used for evaluating and quantifying hirsutism.Results: The mean Fasting plasma insulin12.42±2.41 (mIU/dl), the mean of HOMA-IR was 3.14±1.18. The mean value of dehydroepiandrosteronesulphate (DHEAS) 355.78±15.41 mcg/dl. There was statistically significant reduction in modified Ferriman-Gallwey scoring in before and after treatment (12.38± 1.55 vs. 9.62±1.6), the p value was 0.00001. The number of patients with menstrual irregularities were reduced from 63.3% to 20% after treatment and this difference is statistically significant (p=0.04).Conclusions: Hirsutism is associated with insulin resistance and DHEAS concentration was high. Modified Ferriman-Gallwey score was significantly reduced and there was significant weight loss and improvement in menstrual irregularities after treatment.

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