scholarly journals Evaluation the influence of core stability exercise on standing stability of hemiplegic cerebral palsy

2020 ◽  
Author(s):  
mohammad Karimi

Abstract Background: Cerebral palsy (CP) is one of the most common neurological disorders influences the abilities of the subjects to stand and walk. Various kinds of exercise are recommended to improve the stability of CP subjects during quiet standing. However, there is no evidence regarding the effects of core stability exercise on stability of CP subjects. Therefore, the aim of this research was to determine the efficiency of this exercise on stability of CP subjects.Method: Two group of normal and CP children were recruited in this study (10 subjects). The stability of the subjects was determined by use of a Kistler forceplate. The stability of the subjects was measured by Approximate entropy (ApEn) based on COP sways. The dynamic stability was evaluated by Berge balance scale. Ashworth scale was used to determine the spasticity of lower limb muscles groups. Results: The mean value of ApEn of CP patients in the anteroposterior and mediolateral directions were 0.465±0.11 and 0.426±0.99, respectively compared to 1.02±0.11 and 0.426±0.099 for normal subjects. There was a significant increase in ApEn of CP subjects before and after exercise (p-value<0.05). The mean value of Berge scale was 46.2±5.77 and 51.87±3.9 before and after exercise, respectively.Conclusion: As lower value of ApEn associated with decrease in complexity, higher rigidity and unstability, it can be concluded that CP subjects were unstable than normal subjects. Use of core stability exercise improves complexity of the system and improves the stability of the subjects due to its effect on muscular spasm.

Author(s):  
Hossein Akbari Aghdam ◽  
Mahsa Kavyani ◽  
Maryam Bosak ◽  
Mohammad Taghi Karimi ◽  
Mehdi Motififard

AbstractAnterior cruciate ligament (ACL) is the most frequently injured ligament in the knee and is often injured during sport-related activities. ACL injuries influence the abilities of the subjects during standing and walking. Although early surgical intervention is preferred treatment for the majority of knee surgeons, the effect of this approach on postural stability of patients is not fully understood. Therefore, the aim of this study was to determine the difference between stability of ACL-reconstructed subjects before and after surgery. A group of 15 consecutive ACL injured patients participated in this study. Postural stability of the patients was evaluated 1 week before and 6 months after surgery (ACL reconstruction with hamstring autograft). A Kistler force plate was used to evaluate center of pressure (COP) sway during quiet standing. The mean values of the COP parameters were obtained in pre and postsurgery conditions. Paired sample t-test was used to evaluate the difference between the stability parameters of the two conditions. The significant point was set at 0.05. The mean value of path length of COP velocity in mediolateral (ML) direction was 1,485.57 ± 479.42 mm and 2,641.33 ± 996.26 mm before and after surgery, respectively (p-value = 0.01). Although the mean value of COP velocity in anteroposterior and ML directions increased after surgery, the difference was only significant for velocity in ML direction (p-value = 0.049). The results of this study showed that the standing stability of those with ACL reconstruction decreased significantly after ACL reconstruction, which may be due to the effects of the surgery on sensory mechanism of ACL and inability of patients to return to their previous deep sense perception and knee proprioception.


2012 ◽  
Vol 12 (05) ◽  
pp. 1250029
Author(s):  
SAED MOHSEN MIRBOD ◽  
MOHAMMAD TAGHI KARIMI ◽  
A. ESHRAGHI

Footwear is an extremely important clothing item worn by all individuals. Currently, there is insufficient research regarding the influence of dress shoes on standing stability and energy consumption while walking. Therefore, the aim of this study was to evaluate the influence of dress shoes on the performance of normal subjects based on stability and energy consumption analysis. Fifteen normal subjects were recruited in this research study to stand and walk with and without shoes. The stability of the subjects in quiet standing was measured by the use of a force plate based on center of pressure (COP) sway. The energy consumption was evaluated by a heart rate monitoring system (Polar Electro) based on the physiological cost index (PCI). The mean values of PCI while walking with and without shoes were 0.29 ± 0.117 and 0.265 ± 0.112 beats/m, respectively (p-value > 0.05). The amplitudes of COP sways in the mediolateral and anteroposterior directions were 10.4 ± 3.5 and 25 ± 6.92 mm while standing with shoes and 9.3 ± 2.84 and 22.5 ± 5.25 mm in barefoot standing, respectively (p-value > 0.05). It can be concluded that wearing dress shoes does not influence the performance of subjects while standing or walking.


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1275.1-1275
Author(s):  
D. Simon ◽  
A. Kleyer ◽  
S. Bayat ◽  
J. Knitza ◽  
L. Valor ◽  
...  

Background:Preclinical models have indicated that biomechanical stress can trigger entheseal inflammation (1). Furthermore, enthesitis is a hallmark of psoriatic arthritis (PsA) and spondyloarthritis (SpA), suggesting that mechanoinflammation is an important step in their pathogenesis (2). However, the relation between mechanical stress and enthesitis in humans is poorly investigated. Competitive badminton is a demanding stop-and-go sport that strains entheseal sites in particular and provides an opportunity to assess the impact of physical activity on the development of an instant inflammatory response in the entheses.Objectives:To evaluate the influence of mechanical stress on the development of immediate enthesitis.Methods:BEAT (Badminton Enthesitis Arthrosonography Study) is an interventional study that assessed entheses in competitive badminton players before and immediately after a 60-minute intensive training session by ultrasound. Power Doppler (PD) signal and Gray-Scale (GS) changes were evaluated at the insertions sites of both Achilles tendon, patellar tendons and lateral humeral epicondyles and quantified using a validated scoring system (3). Pre- and post-training scores were compared using linear mixed-effects models. We used interaction terms to assess possible differential effects on patellar, elbow and Achilles entheses.Results:Thirty-two badminton players (22 men, 10 women) with an average age of 31.1±13.0 years were included (Table 1). On average, they had been playing badminton for 16.2±10.1 years. 192 entheseal sites were examined twice. The respective empirical total scores for PD examination were 0.1 (0.3) before and 0.5 (0.9) after training (Figure 1). Mean total GS scores were 2.9 (2.5) and 3.1 (2.5) before and after training, respectively. The mean total PD score difference of 0.4 between pre- and post -training was significant with a p value of 0.0014, whereas the p value for the mean total GS score difference of 0.2 was 0.63. Overall, seven participants (22%) showed an increased empirical total PD score. A mixed-effects model showed a significant increase of PD scores after training, with a mean increase per site of 0.06 (95%CI 0.01 to 0.12, p=0.017).Table 1.Baseline characteristicsDemographic characteristicsN, total32Females, N (%)10 (31.3)Age, years (mean ± SD)36.1 ± 13.0Height, cm (mean value ± SD)178.6 ± 9.9Body weight, kg (mean value ± SD)74.7 ± 13.5Smoking, N (%)11 (34.4)Alcohol, N (%)24 (75.0)Concomitant DiseasesInflammatory bowel disease, N (%)0Psoriasis, N (%) 0Uveitis, N (%)0Diabetes mellitus, N (%)0Hypertension, N (%)2 (6.3)Sports historyYears Badminton (mean ± SD)16.2 ± 10.1Figure 1.Ultrasound scores before and after training Figure 1. A Spaghetti plots depicting inividual Gray-Scale and Power Doppler ultrasound scores before and after trainingConclusion:Mechanical stress leads to rapid inflammatory responses in the entheseal structures of humans. These data support the concept of mechanoinflammation in diseases associated with enthesitis. However, while such responses may be self-contained in healthy subjects, they may be prolonged and more pronounced in certain risk groups, such as patients with PsA or SpA.References:[1]Cambré I, et al. Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis. Nature Communications. 2018; 9:4613.[2]Schett G, et al. Enthesitis: from pathophysiology to treatment. Nat Rev Rheumatol. 2017; 13:731-741.[3]Balint PV, et al. Reliability of a consensus-based ultrasound definition and scoring for enthesitis in spondyloarthritis and psoriatic arthritis: an OMERACT US initiative. Annals of the Rheumatic Diseases. 2018; 77:1730.Disclosure of Interests:David Simon: None declared., Arnd Kleyer: None declared., Sara Bayat: None declared., Johannes Knitza: None declared., Larissa Valor: None declared., Marina Schweiger: None declared., Georg Schett: None declared., Koray Tascilar: None declared., Axel Hueber Grant/research support from: Novartis Research Grant.


2012 ◽  
Vol 140 (11-12) ◽  
pp. 746-750 ◽  
Author(s):  
Lidija Dimitrijevic ◽  
Bojko Bjelakovic ◽  
Milica Lazovic ◽  
Ivona Stankovic ◽  
Hristina Colovic ◽  
...  

Introduction. Aquatic exercise is one of the most popular supplementary treatments for children with neuro-motor impairment, especially for cerebral palsy (CP). As water reduces gravity force which increases postural stability, a child with CP exercises more easily in water than on land. Objective. The aim of the study was to examine aquatic exercise effects on gross motor functioning, muscle tone and cardiorespiratory endurance in children with spastic CP. Methods. The study included 19 children of both sexes, aged 6 to 12 years, with spastic CP. They were included in a 12-week aquatic exercise program, twice a week. Measurements of GMFM (Gross Motor Function Measurement), spasticity (MAS ? Modified Ashworth Scale), heart rate (HR) and maximal oxygen consumption (VO2max) were carried out before and after treatment. The measurement results were compared before and after treatment. Results. GMFM mean value before therapy was 80.2% and statistically it was significantly lower in comparison to the same value after therapy, which was 86.2% (p<0.05). The level of spasticity was considerably decreased after therapy; the mean value before treatment was 3.21 according to MAS, and after treatment it was 1.95 (p<0.001). After treatment there was a statistically significant improvement of cardiorespiratory indurance, i.e., there was a significant decrease in the mean value of HR and a significant increase of VO2max (p<0.001). Conclusion. Aquatic exercise program can be useful in improving gross motor functioning, reducing spasticity and increasing cardiorespiratory endurance in children with spastic CP.


Author(s):  
M. Smitha

Background: Hirsutism is defined as presence of excess coarse hairs appear in male pattern in women.There is various aetiology of hirsutism like Idiopathic hirsutism, PCOS, androgen secreting ovarian tumours, menopause, CAH, Cushing’s syndrome, drugs which increases testosterone level, insulin resistance and tumour secreting androgen. We have designed present study with an aim to study the clinicoepidemiology, metabolic and hormonal profile of women with hirsutism in Konaseema region of Andhra Pradesh.Methods: All patients with hirsutism attending gynaecology outpatient department were selected for study based on inclusion and exclusion criteria. After that patient were examined clinically, BMI was calculated for each patient. Patients were clinically evaluated for signs of excess androgen secretion, Cushing syndrome, metabolic syndrome and hyperprolactinemia. Modified Ferriman-Gallwey scoring system was used for evaluating and quantifying hirsutism.Results: The mean Fasting plasma insulin12.42±2.41 (mIU/dl), the mean of HOMA-IR was 3.14±1.18. The mean value of dehydroepiandrosteronesulphate (DHEAS) 355.78±15.41 mcg/dl. There was statistically significant reduction in modified Ferriman-Gallwey scoring in before and after treatment (12.38± 1.55 vs. 9.62±1.6), the p value was 0.00001. The number of patients with menstrual irregularities were reduced from 63.3% to 20% after treatment and this difference is statistically significant (p=0.04).Conclusions: Hirsutism is associated with insulin resistance and DHEAS concentration was high. Modified Ferriman-Gallwey score was significantly reduced and there was significant weight loss and improvement in menstrual irregularities after treatment.


Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 1206-1206
Author(s):  
Anna Serra ◽  
Sonia Carturan ◽  
Enrico Gottardi ◽  
Francesca Arruga ◽  
Francesca Messa ◽  
...  

Abstract Recently, a JAK2V617F mutation has been described in the majority of patients with polycythemia vera (PV), and in a subset of patients with essential thromocythemia (ET) and idiopathic myelofibrosis (IMF). Similarly, PRV-1 has been found overexpressed in many of these patients. The aim of the study was to correlate PRV-1 and WT1 expression with the presence of JAK2 mutation in order to establish whether these markers identify the same subset of patients. Using a Real Time PCR we studied the expression level of PRV1 and WT1 in 330 patients including 26 IMF, 156 PV, 122 ET, 16 HES. 10 familiar forms of PV were included. In addition a control group of 50 healthy subject and 60 reactive conditions were studied All the patients were analyzed for the presence of JAK2 mutation using the ABI Prims 3100 genetic analyzer. We found that JAK2 mutation was present in 50 % of IMF, 93% of PV and 55% of ET and 6% of HES. PRV-1 was increased in 84% of IMF, 98% of PV and 90% of ET and it was not increased in HES. WT1 was increased in 99% of IMF, 45% of PV and 42% of ET and 100% of HES. No mutations of JAK2 were detected in normal subjects or in reactive conditions. Both WT1 and PRV1 were expressed at low levels in normal subject (for PRV1 the mean value of 2-Delta Delta Ct was 2,05; range 0,05–5,46; for WT1 mean value WT1 copies/104 ABL copies of 4; range 0–20). The mean value of WT1 copies/104 ABL copies in IMF was 306 (p=0,00004 compared to normal controls), in PV was 156 (p=0,0001), in ET was 202 (p=0,0002) and in HES was 161 (p=0,0004). PRV1 mean value in IMF was 144 expressed as 2−Delta Delta Ct, and it was 423 in PV and 290 in ET. Moreover the correlation between the three markers allowed to establish that both WT1 and PRV1 were higher in JAK2 mutated samples when compared to wild type JAK2 with a p value of 0,001 for WT1 and 0,004 for PRV1. In spite of these we were able to identify a subset of patients affected by IFM characterized by increased values of PRV1 and WT1 but not by JAK2 mutation (34%) and a small subset 15% characterized only by WT1 overexpression. Only 5% of PV and 35% of ET patients expressed only PRV-1 but not JAK2 mutation and WT1 expression. HES patients overexpressed WT1 but not PRV1 and only one patient presented the JAK2 mutation. Finally 10 patients affected by familiar form of PV were studied. All the subjects showed normal PRV-1 expression but high level of WT1 transcript and 9 out of 10 presented the JAK2 mutation. This study demonstrates that the combination of all these markers is probably useful for a correct diagnosis of these patients but further studies are required to stratify these patients and to better classify them according to the presence of molecular lesions.


2014 ◽  
Vol 1 (2) ◽  
pp. 1
Author(s):  
Yayun Siti Rochmah ◽  
Minidian Fasitasari

Background: Banana counted as nearly perfect food since it contains six nutrients : water , sugar , proteins , fats , vitamins , and minerals . Because of that , bananas are often used as a staple food for most people because of its nutritional value. However, sometimes people do not realize the benefits of bananas as a whole , from leaves , fruits , flowers and stems of the bananas . Penggaron Lor society , still minimal in using the banana plant . Usually the community will sell fruit and leaves to the market , so that the results obtained from the banana plant community less than optimal. Method : This study is an observational analytic study . The research was done in the Village of Penggaron Lor Semarang , and was conducted in March-June 2014. The instrument in this research was primary data obtained directly from respondents through interviews using questionnaires distributed before and after counseling . To determine whether there are differences in knowledge before and after counseling on the benefits of banana plants as a medium for maintaining oral hygiene, statistical test Wilcoxon Sign Ranks test was conducted, and processed with SPSS. Result: The results of SPSS calculation because the data is not normal ( p value < 0.05), then the data was processed using the non-parametric test for two sample pairs , ie Wilcoxon Sign Ranks test , and obtained p value of 0.008 . This means that there was a significant difference between the mean value of the pre-test and post-test. Conclusion : there are differences in knowledge before and after counseling , counseling means that a significant impact on respondents' knowledge of the benefits of banana plants for maintain oral health.


2021 ◽  
Vol 4 (1) ◽  
pp. 24-30
Author(s):  
Zhan Chengwu ◽  
Florenly ◽  
Johannes Bastira Ginting ◽  
Fioni

Orthopedic surgery is a surgical action associated with the correction of musculoskeletal system deformities and orthopedic problems that aim to improve function by restoring movement and stability and reducing pain and disabilities. Early mobilization is a prominent factor in speeding up postoperative recovery and may prevent postoperative complications. This study aims to find out the influence before and after early mobilization of changes in pain levels in orthopedic postoperative clients at RSU Royal Prima. This type of research uses a correlational descriptive research design, using the One Group Pretest-Postest approach. The location of this study was conducted at RSU Royal Prima Medan in March 2021. The population of all patients’ post-surgery orthopedic hospitalization amounted to 176 patients. The size of the sample uses the formula Structural Equation Modelling (SEM), then the number of samples is determined to be 100 people. Univariate analysis, bivariate with t-dependent test (paired t-test) with a meaningful limit of 0.05. The results of the study that there was a change in the level of pain Wilcoxon test results at the time of the pre-test the result of the mean value of 3.82, at the time of the post-test test the mean value was 2.34. So the result of Z = -5,358 then p-value as much as 0.004 < 0.05 so that Ho is rejected and Ha accepts. The conclusion of the level of pain before early mobilization in the client post orthopedic surgery the majority feels even more pain and the minority experience severe pain. The level of pain after early mobilization in the majority of orthopedic postoperative clients was slightly more painful and the minority felt even more pain. There is an early mobilization effect on pain changes in orthopedic postoperative clients in patients in the hospital room of RSU Royal Prima in 2021.


1983 ◽  
Vol 22 (05) ◽  
pp. 246-250 ◽  
Author(s):  
M. Al-Hilli ◽  
H. M. A. Karim ◽  
M. H. S. Al-Hissoni ◽  
M. N. Jassim ◽  
N. H. Agha

Gelchromatography column scanning has been used to study the fractions of reduced hydrolyzed 99mTc, 99mTc-pertechnetate and 99mTc-chelate in a 99mTc-glucoheptonate (GH) preparation. A stable high labelling yield of 99mTc-GH complex in the radiopharmaceutical has been obtained with a concentration of 40-50 mg of glucoheptonic acid-calcium salt and not less than 0.45 mg of SnCl2 2 H2O at an optimal pH between 6.5 and 7.0. The stability of the complex has been found significantly affected when sodium hydroxide solution was used for the pH adjustment. However, an alternative procedure for final pH adjustment of the preparation has been investigated providing a stable complex for the usual period of time prior to the injection. The organ distribution and the blood clearance data of 99mTc-GH in rabbits were relatively similar to those reported earlier. The mean concentration of the radiopharmaceutical in both kidneys has been studied in normal subjects for one hour with a scintillation camera and the results were satisfactory.


2017 ◽  
Vol 4 (2) ◽  
pp. 14
Author(s):  
Putri Megasari

Hepatitis has become a health problem in the world. The hepatitis virus infected many people. According to the teacher of MTsN 02 Bondowoso more than 20 students have hepatitis A viral infection. The purpose of this research was to know the differences of students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study used pre-experimental (pre-post test design). This study used stratified random sampling technique, 127 students from 270 sample involved this research,and 143 students was excluded. We used questionnaires to collect data. The results showed that the mean value of the students 'knowledge about hepatitis A before counseling in MTsN 02 Bondowoso 2015 was 83.96 with the lowest value of 37.5 and the highest value was 100. The mean value of the students' knowledge about hepatitis A after counseling in MTsN 02 Bondowoso 2015 was 93.21 with the lowest value waf 62.5 and the highest value was 100. Paired t test showed that t (-9.07) > t table (1.98), the null hypothesis (H0) was rejected. There was a difference between students' knowledge about hepatitis A before and after counseling in MTsN 02 Bondowoso 2015. This study showed that routine counseling by healthcare provider was important to prevent hepatitis A infection.; Keywords: counseling, knowledge of students, hepatitis


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