An Overview on Adult Acne, Its Pathogenesis, Clinical Presentation, Treatment and Scope in Homoeopathy

2021 ◽  
Vol 34 (04) ◽  
pp. 291-299
Author(s):  
Rashmi Sharma ◽  
Deepti Dewan
Keyword(s):  
Bacterial Resistance ◽  
Late Onset ◽  
Holistic Approach ◽  
Poor Quality ◽  
Future Research ◽  
Adult Women ◽  
Lactation Period ◽  
General Acceptance ◽  
High Prevalence

AbstractAdult acne is defined as a presence of acne beyond the age of 25 years. Two main subtypes can be identified: persistent acne and late-onset acne (beginning after the age of 25 years), which are responsible for 80 and 20% of cases, respectively. Women have a high prevalence and incidence when compared with men. Hyperandrogenism is the main aetiology associated with acne in this age group. Stress-related worsening of acne is a common complaint. Due to the visibility of acne, it is known to have psychosocial impact that can influence person's perceptions regarding their self-appearance, resulting in poor quality of life. Adult acne is often refractory to treatment as older skin presents increased irritancy to topical applications and has potential for bacterial resistance. Treatment failures with antibiotics occur in up to 80% of adult women. Antiandrogens are associated with the risk of feminisation of male foetus, hepatotoxicity, hyperkalaemia etc. Isotretinoin which is given in severe cases is proved to be potent teratogen. In this backdrop, there has been a need for gentle and effective way of treatment, and homoeopathy has the answer. Homoeopathy has a holistic approach having the general acceptance and compliance amongst masses; it has been considered safe in pregnancy and during lactation period. Further, no bacterial resistance develops after prolonged use of homoeopathic medicines. Earlier studies conducted signify the action of homoeopathic medicines in the treatment of adolescent acne with effective results. Not many studies have focused or conducted on the adult acne. This review suggests conducting the future research studies on adult acne through homoeopathic medicine.

Inline Inspection: Both Effective Data Collection and Interpretation Needed to Achieve High Quality Reporting Results

2010 ◽  
Author(s):  
James R. Walker ◽  
Paul Mallaburn ◽  
Derek Balmer
Keyword(s):  
Financial Risk ◽  
Service Providers ◽  
Holistic Approach ◽  
Poor Quality ◽  
International Standards ◽  
Quality Reporting ◽  
Certification Standard ◽  
Consensus Standard ◽  
Inspection Data

Historically, pipeline operators have tended to place more weight on inline inspection tool specifications than on the inherent design and reporting capabilities of the service providers themselves. While internal collection of integrity data is very important, it’s imperative that vendors, also, have high levels of expertise and effective quality control systems in place to successfully analyze exceedingly high volumes of inspection data. The quality of inspection information is vital to assessing if a pipeline is fit for purpose now and/or into the future. Integrity managers attempting to reduce overall operating risk by making decisions based on inaccurate or poor quality reporting are in fact exposing their networks to greater safety and financial risk. Recognizing these risks and that inline inspection (ILI) is an overall system that needs to be formally qualified, operators and ILI service providers have collaborated to develop several international standards. The most recent is the umbrella API-1163 industry consensus standard, which is now being widely adopted, primarily in USA. This standard provides requirements and recommended practices for qualification of the entire ILI process. Two companion standards: ASNT In-line Personnel Qualification and Certification Standard No. ILI-PQ and NACE Recommended Practice In-Line Inspection of Pipelines RP0102 combine to address specific requirements for personnel who operate and analyze the results of ILI systems. In Europe, the Pipeline Operators Forum (POF) has, also, established specific requirements for ILI reporting processes and data formats. However, these standards do not define how operators and vendors must meet these requirements. To follow will be a story about how an ILI service provider embraced a holistic approach to address these standards’ requirements, in particular in the areas of data analysis, reporting, and dig verification due to their significant importance in assuring the final quality of its deliverables. A key outcome desired will be to provide operators with greater insight into what best practices and technologies ILI service providers should have embraced and invested in to insure reliable service delivery.

scholarly journals Vulnerability in the elderly

2021 ◽  
Vol 64 (3) ◽  
pp. 62-67
Author(s):  
Ana Popescu ◽  
◽  
Gabriela Soric ◽  
Victoria Federiuc ◽  
Vitalie Ojovanu ◽  
...  
Keyword(s):  
Genetic Factors ◽  
Functional Decline ◽  
The Elderly ◽  
Poor Quality ◽  
Important Target ◽  
Increased Risk ◽  
High Prevalence ◽  
Assessment Measures ◽  
Cognitive Problems

Background: Aging process involves an increased risk for the development of vulnerability, because senescence is a process characterized by a multitude of changes that influence the living conditions and health of the individuals. In geriatrics, the term “vulnerability” implies a multidimensional aspect, among which, multimorbidity, functional incapacity, socio-economic and cognitive problems in the elderly. The main objective of the article is to systematize data from the literature through the analysis of the concept and prevalence of vulnerability, assessed by the score Vulnerable Elders Survey-13 (VES-13) in the elderly. For this purpose, publications from the database GoogleSearch, PubMed, Hinari, etc. were analyzed. The information was systematized, highlighting the main aspects of the contemporary vision of the last 5 years.A series of studies (USA, Brazil, etc.) revealed a high prevalence of vulnerability in the elderly according to the VES-13 score, it was estimated in respondents aged > 65 years, between 40-50% of cases were vulnerable people, with a score ≥ 3 p. The vulnerability of the elderly results from different conditions, correlated with each other, especially biological, social and genetic factors. There was a functional decline between 13 and 24% of cases, especially in the elderly over 75 years, and an association with health problems, mobility and low autonomy in over 50% of cases, with a poor quality of life and increased risk of institutionalization. Conclusions: Vulnerability assessment measures are important for identifying older people at high risk of deteriorating health, which is an important target for interdisciplinary intervention.

Couples Facing Cancer

2021 ◽  
pp. 729-736
Author(s):  
Hoda Badr ◽  
Courtney Bitz
Keyword(s):  
Routine Care ◽  
Poor Quality ◽  
Psychosocial Adaptation ◽  
Future Research ◽  
Great Promise ◽  
Clinical Implications ◽  
Social Challenges ◽  
Healthcare Settings ◽  
Care And Support

Cancer survivors experience significant physical, psychological, and social challenges that contribute to poor quality of life. Intimate partners provide critical care and support across the cancer continuum, but they report psychological distress, lack basic healthcare knowledge and skills, and experience increased tension and conflict in their relationships with survivors. Couple-based interventions hold great promise in cancer because they can simultaneously address survivor, partner, and relationship concerns. However, they are seldom implemented in healthcare settings as part of routine care. This chapter will therefore integrate what research has taught us about couples and cancer and what we have learned from couples in the clinical setting. We begin with an overview of challenges faced by couples across the cancer continuum, including biopsychosocial stressors. Next, we describe different perspectives that have shaped descriptive and intervention research on couples’ psychosocial adaptation to cancer. We conclude with clinical implications and directions for future research.

scholarly journals Report from a multidisciplinary meeting on anxiety as a non-motor manifestation of Parkinson’s disease

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Gregory M. Pontone ◽  
Nadeeka Dissanayaka ◽  
Liana Apostolova ◽  
Richard G. Brown ◽  
Roseanne Dobkin ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Expert Panel ◽  
Motor Impairment ◽  
Future Research ◽  
Severe Problem ◽  
High Prevalence ◽  
Expert Meeting ◽  
Clinician Scientist

AbstractAnxiety is a severe problem for at least one-third of people living with Parkinson’s disease (PD). Anxiety appears to have a greater adverse impact on quality of life than motor impairment. Despite its high prevalence and impact on daily life, anxiety is often undiagnosed and untreated. To better address anxiety in PD, future research must improve knowledge about the mechanism of anxiety in PD and address the lack of empirical evidence from clinical trials. In response to these challenges, the Parkinson’s Foundation sponsored an expert meeting on anxiety on June 13th and 14th 2018. This paper summarizes the findings from that meeting informed by a review of the existing literature and discussions among patients, caregivers, and an international, clinician-scientist, expert panel working group. The goal is to provide recommendations to improve our understanding and treatment of anxiety in PD.

scholarly journals Periapical Status and Quality of Root Fillings and Coronal Restorations in an Adult Turkish Subpopulation

2010 ◽  
Vol 04 (01) ◽  
pp. 017-022 ◽  
Author(s):  
Nimet Gencoglu ◽  
Filiz Namdar Pekiner ◽  
Birsay Gumru ◽  
Dilek Helvacioglu
Keyword(s):  
Statistical Analysis ◽  
Root Canal ◽  
Poor Quality ◽  
Apical Periodontitis ◽  
Panoramic Radiographs ◽  
High Prevalence ◽  
Chi Squared ◽  
Low Prevalence ◽  
The Relationship

ABSTRACTObjectives: To investigate the quality of root fillings and coronal restorations and their association with periapical status in an adult Turkish subpopulation.Methods: A total of 400 subjects were examined. Panoramic radiographs of all participants and additional periapical radiographs of affected teeth were processed. The frequency of root canal treatment and the periapical status of all root filled teeth were evaluated. The relationship between the radiographic quality of root fillings and coronal restorations was examined by chi-squared statistical analysis.Results: A total of 9460 teeth were examined. The total number of root filled teeth was 890 (9.39%), and 658 (73.9%) had apical periodontitis (AP). There was a significant correlation between the presence of periapical pathology and inadequate root canal fillings (P <.05). Presence of AP in root filled teeth was associated with inadequate adaptation of the filling (OR=1.097; P=0.54), and with poor radiographic quality of the coronal restoration (OR=0.91; P=0.70), and with poor radiographic quality of the filling restoration (OR=0.97; P=0.92). Only 24.5% of the root fillings were adequate. The highest percentage of root fillings was found in maxillary right first molars (6.9%).Conclusions: The results demonstrate a low prevalence of root-filled teeth and poor quality of coronal restorations and root fillings consistent with a high prevalence of apical periodontitis in a Turkish subpopulation. (Eur J Dent 2010;4:17-22)

Strong Artificial Intelligence and Consciousness

2020 ◽  
Vol 07 (01) ◽  
pp. 63-72 ◽  
Author(s):  
Gee Wah Ng ◽  
Wang Chi Leung
Keyword(s):  
Artificial Intelligence ◽  
Language Processing ◽  
Human Life ◽  
Autonomous Systems ◽  
Holistic Approach ◽  
Future Research ◽  
Strong Ai ◽  
Strong Artificial Intelligence ◽  
Future Research Directions

In the last 10 years, Artificial Intelligence (AI) has seen successes in fields such as natural language processing, computer vision, speech recognition, robotics and autonomous systems. However, these advances are still considered as Narrow AI, i.e. AI built for very specific or constrained applications. These applications have its usefulness in improving the quality of human life; but it is not good enough to do highly general tasks like what the human can do. The holy grail of AI research is to develop Strong AI or Artificial General Intelligence (AGI), which produces human-level intelligence, i.e. the ability to sense, understand, reason, learn and act in dynamic environments. Strong AI is more than just a composition of Narrow AI technologies. We proposed that it has to be a holistic approach towards understanding and reacting to the operating environment and decision-making process. The Strong AI must be able to demonstrate sentience, emotional intelligence, imagination, effective command of other machines or robots, and self-referring and self-reflecting qualities. This paper will give an overview of current Narrow AI capabilities, present the technical gaps, and highlight future research directions for Strong AI. Could Strong AI become conscious? We provide some discussion pointers.

Prevalence of enthesopathies in adults with X-linked hypophosphatemia : analysis of risk factors

2021 ◽  
Author(s):  
Julia Herrou ◽  
Axelle Salcion Picaud ◽  
Louis Lassalle ◽  
Laurence Pacot ◽  
Catherine Chaussain ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medical Records ◽  
Alveolar Bone ◽  
Poor Quality ◽  
Dental Disease ◽  
X Rays ◽  
Reference Center ◽  
High Prevalence ◽  
Center For Rare Diseases

Abstract Context Enthesopathies are the determinant of a poor quality of life in adults with X-linked hypophosphatemia (XLH). Objective To describe the prevalence of patients with enthesopathies and to identify the risk factors of having enthesopathies. Design and setting Retrospective study in the French Reference Center for Rare Diseases of the Calcium and Phosphate Metabolism between June 2011 and December 2020. Patients Adults XLH patients with full body x-rays performed using the EOS® low-dose radiation system and clinical data collected from medical records. Interventions None. Main Outcome Measures Demographic, PHEX mutation, conventional treatment and dental disease with the presence of enthesopathies. Results Of the 114 patients included (68% women, mean age 42.2±14.3 years), PHEX mutation was found in 105 patients (94,6%), 86 (78%) had been treated during childhood. Enthesopathies (spine and/or pelvis) were present in 67% of the patients (N=76). Patients with enthesopathies were significantly older (p = 0,001) and more frequently reported dental disease collected from medical records (p = 0,03). There was no correlation between the PHEX mutations and the presence of enthesopathies. Sixty -two patients had a radiographic dental examination in a reference center. Severe dental disease (number of missing teeth, number of teeth endodontically treated, alveolar bone loss and proportion of patients with five abscesses or more) was significantly higher in patients with enthesopathies. Conclusion Adults XLH patients have a high prevalence of enthesopathies in symptomatic adults patients with XLH seen in a reference center. Age and severe dental disease were significantly associated with the presence of enthesopathies.

scholarly journals Classification of Uremic Toxins and Their Role in Kidney Failure

2021 ◽  
pp. CJN.02660221
Author(s):  
Mitchell Rosner ◽  
Thiago Reis ◽  
Faeq Husain-Syed ◽  
Raymond Vanholder ◽  
Colin Hutchison ◽  
...  
Keyword(s):  
Classification Scheme ◽  
Clinical Symptoms ◽  
Holistic Approach ◽  
Physicochemical Characteristics ◽  
Consensus Conference ◽  
Uremic Toxins ◽  
Future Research ◽  
Major Focus

Advances in our understanding of uremic retention solutes, as well as improvements in hemodialysis membranes and other techniques designed to remove uremic retention solutes, offer opportunities to readdress the definition and classification of uremic toxins. A consensus conference was held to develop recommendations for an updated definition and classification scheme based upon a holistic approach that incorporates physicochemical characteristics, and, dialytic removal patterns of uremic retention solutes and their linkage to clinical symptoms and outcomes. The major focus is on removal of uremic retention solutes by hemodialysis. The identification of representative biomarkers for different classes of uremic retention solutes and their correlation to clinical symptoms and outcomes may facilitate personalized and targeted dialysis prescriptions to improve quality of life, morbidity, and mortality. Recommendations for areas of future research were also formulated, aimed at improving understanding of uremic solutes and improving outcomes in patients with chronic kidney disease.

scholarly journals Reiki: a modality towards holistic approach to cancer cure

2017 ◽  
Vol 4 (6) ◽  
pp. 1790
Author(s):  
Sonia Puri ◽  
Dinesh Kumar Walia ◽  
Har Ashish Jindal
Keyword(s):  
Alternative Medicine ◽  
Complementary Therapies ◽  
Holistic Approach ◽  
Future Research ◽  
Evidence Based ◽  
Treatment Protocols ◽  
Cancer Management ◽  
Near Future ◽  
Major Criticism

Reiki is one of the complementary and alternative medicine modalities which have been accepted and appreciated, globally. Many evidence based studies have validated its role in cancer. Reiki can play a major role in changing the patient’s outlook towards life and increasing the patient’s ability as well as willingness to comply with physician’s instructions and adhere to treatment protocols. The goal of Reiki treatments is to strengthen the flow of energy through these blocked or disturbed pathways, thus decreasing pain and enhancing the body’s natural ability to fight illnesses and heal itself. It combats the nausea caused from chemotherapy. One of the major criticism is lack of scientific foundation. There has been effort to collaborate conventional and complementary therapies to improve the quality of future research. In the near future, it may be considered as one of the advanced modalities of alternative medicine used in conjunction with conventional therapy for holistic approach for cancer management.

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