195 Effect of feeding a licorice extract to Japanese Black cows on embryo production performance after superovulation treatment

2019 ◽  
Vol 31 (1) ◽  
pp. 222
Author(s):  
Y. Aoyagi ◽  
M. Takeuchi ◽  
Y. Oono ◽  
M. Urakawa ◽  
M. Koiwa
Keyword(s):  
Treatment Group ◽  
Glycyrrhizic Acid ◽  
Embryo Quality ◽  
Production Performance ◽  
Control Group ◽  
Embryo Production ◽  
Significant Difference ◽  
Licorice Extract ◽  
The Mean ◽  
Effect Of Feeding

The objective was to determine the effect of feeding a licorice extract that contains glycyrrhizic acid, which is known to have a liver function-enhancing effect, on embryo production performance after superovulation treatment in Japanese Black cows. Japanese Black breed cows (n=136) that had calved 1 to 4 times and had normal uteri as seen by ultrasonography after at least 40 days from the last calving were used as test animals. Animals in the treatment group (n=90) were continuously fed 20g head−1 d−1 of a licorice extract (Kanzou, Fabric Onishi Co. Ltd., Osaka, Japan), with at least 13% glycyrrhizic acid content) once a day, mixed with the formula feed, for 60 to 90 days starting from around the day of calving until ova/embryos were collected. The control group (n=46) received no Kanzou from the day of the last calving until ova/embryo collection. A total of 20 Armour units (AU) of FSH (Antorin R, Kyoritsu Seiyaku Corporation, Kanagawa, Japan) from porcine pituitary was given intramuscularly (IM) twice a day, morning and evening, for 3 consecutive days (decreasing dose schedule: 5 AU×2, 3 AU×2, and 2AU×2) as the superovulation treatment to the cows at 8 to 11 days post-oestrus in both groups. Prostaglandin F2α 25mg and 15mg (IM) were administered in the morning and evening, respectively, on the third day of FSH administration. Artificial insemination was done at 12 and 24h after the start of oestrus, and ova/embryos were collected using a uterine reflux method on Day 7 post-oestrus. The mean numbers of ova/embryos and transferable embryos collected and the mean embryo quality scores (according to the IETS guidelines) in the treatment and control groups were compared by t-test. A chi-squared test was used to compare the proportion of transferable embryos in the 2 groups. There was no significant difference in the mean number of ova/embryos retrieved between the treatment group (21.7±11.8) and the control group (15.8±11.3), although the former tended (P=0.07) to yield more ova/embryos. There was significant difference (P<0.05) in the mean number of transferable embryos collected in the treatment group (13.1±8.3) than in the control group (8.1±5.3). The mean embryo quality score was significantly greater (P<0.01) in the treatment group (1.6±0.4) than in the control group (2.2±0.6). The proportion of transferable embryos in the treatment group (60.3±26.4%) was also significantly higher (P<0.05) than in the control group (51.2±26.0%). In conclusion, feeding a licorice extract to Japanese Black cows for 60 days or longer improves the quality of embryos obtained after superovulation treatment and leads to an increase in the mean number of transferable embryos per cow.

scholarly journals Dentofacial Changes after Orthodontic Intervention with Eruption Guidance Appliance in the Early Mixed Dentition

2008 ◽  
Vol 78 (2) ◽  
pp. 324-331 ◽  
Author(s):  
Katri Keski-Nisula ◽  
Leo Keski-Nisula ◽  
Hannu Salo ◽  
Kati Voipio ◽  
Juha Varrela
Keyword(s):  
Treatment Group ◽  
Mixed Dentition ◽  
Class I ◽  
Control Group ◽  
Significant Shift ◽  
Facial Height ◽  
Significant Difference ◽  
The Mean ◽  
Maxillary Incisors ◽  
Clinically Significant

Abstract Objective: To evaluate skeletal and dentoalveolar changes induced by the eruption guidance appliance in the early mixed dentition. Materials and Methods: Pre- and posttreatment cephalometric radiographs of 115 consecutively treated children, 62 boys and 53 girls, were compared with those obtained from a control group of 104 children, 52 boys and 52 girls. Pretreatment radiographs were taken at the deciduous-mixed dentition interphase (T1) and after full eruption of all permanent incisors and first molars (T2). The mean age of the children in both groups was 5.1 years at T1 and 8.4 years at T2. Results: A significant difference between the groups at T2 was found in the mandibular length, midfacial length, and maxillomandibular differential. The increase in mandibular length was 11.1 mm in the treatment group and 7.2 mm in the control group. No differences were found in measurements of maxillary position or size. There was a significant shift toward a Class I relationship in the treatment group. Labial tipping and linear protrusion of the mandibular incisors was evident in the treatment group at T2. There was no effect on the inclination or position of the maxillary incisors. Conclusions: Occlusal correction was achieved mainly through changes in the dentoalveolar region of the mandible. In addition, the appliance enhanced condylar growth resulting in a clinically significant increase in mandibular length. No effect was observed on maxillary position, maxillary size, inclination or protrusion of the maxillary incisors, or facial height.

scholarly journals Antibacterial Activity of Lumbricus Rubellus Earthworm Extract Against Porphyromonas Gingivalis as the Bacterial Cause of Periodontitis

2019 ◽  
Vol 7 (6) ◽  
pp. 1032-1036 ◽  
Author(s):  
I Gusti Agung Ayu Dharmawati ◽  
Tjokorda Gde Bagus Mahadewa ◽  
I Putu Eka Widyadharma
Keyword(s):  
Antibacterial Activity ◽  
Treatment Group ◽  
Lumbricus Rubellus ◽  
Control Group ◽  
Inhibitory Zone ◽  
Control Group Design ◽  
Zone Diameter ◽  
Significant Difference ◽  
The Mean

AIM: The purpose of this study was to determine the antibacterial activity of Lumbricus rubellus earthworms through inhibitory zone diameter to the growth of the bacterium Phorphyromonas gingivalis as the cause of periodontitis. METHODS: This was an experimental study with randomised posttest-only control group design. The study was conducted at the Microbiology Research Center laboratory at the Faculty of Dentistry, Airlangga University, Indonesia. The study was conducted in vitro, the sample size was calculated using the Federer formula as many as four agar plates containing bacteria Phorphyromonas gingivalis, with each plate given five different treatments: control (ethanol), Lumbricus rubellus earthworm extract (ECT) with concentrations of 50%, 25%, 12.5%, and 6.25% respectively. The data in the form of inhibition zone diameter (measured in millimetres) obtained were tested using One-Way ANOVA. RESULTS: The mean diameter of the inhibitory zone extract of Lumbricus rubellus earthworm on the growth of Phorphyromonas gingivalis bacteria in the treatment group had significant differences (p < 0.05). The mean inhibition zones between controls and the ECT treatment group (ECT 50%, ECT 25%, ECT 12.5%) were statistically different (p < 0.05), in contrast with ECT 6.25% (p > 0.05) which did not show significant difference with the control group (p > 0.05). CONCLUSION: Lumbricus rubellus earthworm extract with a concentration of 50% has the largest diameter of the inhibitory zone on the growth of the Phorphyromonas gingivalis bacteria. The 6.25% earthworm extract showed no antibacterial activity against the growth of Phorphyromonas gingivalis bacteria.

scholarly journals Teaching English Vocabulary with Greek or Latin Roots to Iranian EFL Students by PLS Sequential Structures

2020 ◽  
Vol 8 (4) ◽  
pp. p73
Author(s):  
Abolfazl Shirban Sasi
Keyword(s):  
Treatment Group ◽  
Teaching Method ◽  
English Word ◽  
Control Group ◽  
Teaching English ◽  
Control Group Design ◽  
Significant Difference ◽  
Efl Students ◽  
The Mean ◽  
And Control

PLS is a newly developed language teaching method which predominantly applies imaginative and random usage of pictures. The present paper explains and reports the application of a PLS technique in teaching English vocabulary with Greek or Latin roots to Iranian EFL learners. A pretest-posttest control-group design was used to investigate the effects of this sequential structures technique. Participants were intermediate level EFL students in two branches of the same language institute in Tehran (N = 94, p ? 0.05). The subjects were randomly assigned into two groups of treatment and control. The experiment lasted for seven one-hour lessons held in successive sessions in three weeks during which 35 Greek and Latin roots were taught with at least three English word examples. For the research instrument, the students were administered a 35-item multiple-choice vocabulary exam for the pre and post tests prior to and immediately after the teaching phase. Consequently, an independent sample T-test was used to examine the outcome of the experiment. At p = .009, the statistical test revealed a significant difference in the gain scores between the two groups. Also, the mean vocabulary gain score of 7.23 for the treatment group as opposed to the mean of 5.35 for the control group illustrated the relative more L2 vocabulary intake for the treatment group.

scholarly journals Spironolactone versus observation in the treatment of acute central serous chorioretinopathy

2017 ◽  
Vol 102 (8) ◽  
pp. 1060-1065 ◽  
Author(s):  
Xinghong Sun ◽  
Yuanlu Shuai ◽  
Wangyi Fang ◽  
Jia Li ◽  
Weizhong Ge ◽  
...  
Keyword(s):  
Treatment Group ◽  
Central Serous Chorioretinopathy ◽  
Complete Resolution ◽  
Subretinal Fluid ◽  
Control Group ◽  
Significant Difference ◽  
Registration Number ◽  
Acute Central Serous Chorioretinopathy ◽  
The Mean ◽  
Randomised Controlled

PurposeTo evaluate the efficacy of oral spironolactone in patients with acute central serous chorioretinopathy (CSC).MethodsThis is a prospective, randomised controlled clinical study. Thirty patients with acute CSC were the participants, including 18 patients who were treated with spironolactone (40 mg orally, twice daily) for 2 months in the experimental group and 12 patients who received observation in the control group. Main outcome measures included the proportion of eyes achieving complete resolution of subretinal fluid (SRF), changes in central macular thickness (CMT), the height of SRF (SRFH), best corrected visual acuity (BCVA) and subfoveal choroidal thickness (SFCT). The follow-up period was 2 months.ResultsComplete resolution of SRF was achieved in 55.6% (10/18) and 8.3% (1/12) of the eyes in the treatment group and the control group, respectively, at 2 months (p=0.018). The mean CMT and SRFH decreased significantly at each visit in both groups (p<0.05), and there was significant difference between the two groups at 2 months (p<0.05 and p<0.05, respectively). BCVA (in logarithm of the minimum angle of resolution; mean) improved in both groups at 2 months (p<0.05). In the treatment group, the mean baseline SFCT significantly decreased from 502.50±87.38 µm to 427.44±74.37 µm at 2 months (p<0.01), while the change from baseline (from 480.33±102.38 µm to 463.75±100.63 µm) was not significant in the control group (p=0.195). But the differences between the two groups in BCVA and SFCT were not significant.ConclusionsOral spironolactone is more effective with a faster absorption of SRF than observations. It is a promising treatment for acute CSC.Trial registration numberChiCTR-IPR-16008428, Results.

Discrete cerebral hypothermia in the management of traumatic brain injury: a randomized controlled trial

2009 ◽  
Vol 110 (6) ◽  
pp. 1256-1264 ◽  
Author(s):  
Odette A. Harris ◽  
Carrie R. Muh ◽  
Monique C. Surles ◽  
Yi Pan ◽  
Grace Rozycki ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Treatment Group ◽  
Temperature Gradient ◽  
Control Group ◽  
Systemic Effects ◽  
Randomized Controlled ◽  
Bladder Temperature ◽  
Significant Difference ◽  
The Mean ◽  
Gcs Score

Object Hypothermia has been extensively evaluated in the management of traumatic brain injury (TBI), but no consensus as to its effectiveness has yet been reached. Explanatory hypotheses include a possible confounding effect of the neuroprotective benefits by adverse systemic effects. To minimize the systemic effects, the authors evaluated a selective cerebral cooling system, the CoolSystem Discrete Cerebral Hypothermia System (a “cooling cap”), in the management of TBI. Methods A prospective randomized controlled clinical trial was conducted at Grady Memorial Hospital, a Level I trauma center. Adults admitted with severe TBI (Glasgow Coma Scale [GCS] score ≤ 8) were eligible. Patients assigned to the treatment group received the cooling cap, while those in the control group did not. Patients in the treatment group were treated with selective cerebral hypothermia for 24 hours, then rewarmed over 24 hours. Their intracranial and bladder temperatures, cranial-bladder temperature gradient, Glasgow Outcome Scale (GOS) and Functional Independence Measure (FIM) scores, and mortality rates were evaluated. The primary outcome was to establish a cranial-bladder temperature gradient in those patients with the cooling cap. The secondary outcomes were mortality and morbidity per GOS and FIM scores. Results The cohort comprised 25 patients (12 in the treatment group, 13 controls). There was no significant intergroup difference in demographic data or median GCS score at enrollment (treatment group 3.0, controls 3.0; p = 0.7). After the third hour of the study, the mean intracranial temperature of the treatment group was significantly lower than that of the controls at all time points except Hours 4 (p = 0.08) and 6 (p = 0.08). However, the target intracranial temperature of 33°C was achieved in only 2 patients in the treatment group. The mean intracranial-bladder temperature gradient was not significant for the treatment group (p = 0.07) or the controls (p = 0.67). Six (50.0%) of 12 patients in the treatment group and 4 (30.8%) of 13 in the control group died (p = 0.43). The medians of the maximum change in GOS and FIM scores during the study period (28 days) for both groups were 0. There was no significant difference in complications between the groups (p value range 0.20–1.0). Conclusions The cooling cap was not effective in establishing a statistically significant cranial-bladder temperature gradient or in reaching the target intracranial temperature in the majority of patients. No significant difference was achieved in mortality or morbidity between the 2 groups. As the technology currently stands, the Discrete Cerebral Hypothermia System cooling cap is not beneficial for the management of TBI. Further refinement of the equipment available for the delivery of selective cranial cooling will be needed before any definite conclusions regarding the efficacy of discrete cerebral hypothermia can be reached.

scholarly journals HUBUNGAN OKSIDA NITRAT DAN NILAI HISTOPATOLOGIS PADA ENDOTOKSEMIA

2016 ◽  
Vol 20 (3) ◽  
pp. 201
Author(s):  
Sotianingsih Sotianingsih ◽  
Suharyo Suharyo ◽  
Lisyani S ◽  
Guntur HA
Keyword(s):  
Nitric Oxide ◽  
Treatment Group ◽  
Control Group ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Termination Time ◽  
Control Group Group

Lipopolysaccharide (LPS) is an endotoxin from the outer membrane of Gram-negative bacteria, which has an important role in the occurrence of sepsis. Exposure to LPS will stimulate increase of nitric oxide (NO). Nitric oxide is a bioregulator of apoptosis and has some sepsis prognostic role of apoptosis regulators within the gastrointestinal cells. The objective of the study is to know if endotoxemia induces an increase in NO levels and histopathology scores as well as the existing relationship between them. This study is an observational intervention. The subjects were 48 male mice Balb/C, divided into 2 groups. The samples consisted of 24 tail as control group (group A) and 24 as treatment group (group B). The A group as well as the B group is divided into 4 subgroups according to the time of termination. The levels of NO were examined by Griess method. Histopathology score was examined by HE and read as a score of 0–5. There was a statistically significant difference between the mean NO in the treatment group with the control group at the termination of the group of 12h (p=0.009), 24h (p=0.015), 36h (p=0.014), 48h (p=0.002) and the whole group (p=0.0001), as well as between the mean histopathology score at the termination time of 12 h (p=0.0001), 24h (p=0.0001), 36h (p=0.0001), 48h (p=0465) and the whole group (p=0.0001). Increase in NO and histopathology scores in all groups of mice (r=0.527) showed a statistically significant correlation. NO levels and histopathology scores are increased during endotoxemia and thus have a significant correlation.

scholarly journals PENGARUH SELF-HYPNOSIS TERHADAP INTENSITAS NYERI DAN TINGKAT KECEMASAN LANSIA PENDERITA OSTEOARTRITIS

Biomedika ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 24
Author(s):  
Chandra Irawan ◽  
Aris Sudiyanto ◽  
Mohammad Fanani
Keyword(s):  
Treatment Group ◽  
Pain Intensity ◽  
The Elderly ◽  
Complementary Therapy ◽  
Mean Value ◽  
Control Group ◽  
Intensity Level ◽  
Osteoarthritis Pain ◽  
Significant Difference ◽  
The Mean

Arthritis or rheumatism in the elderly (called osteoarthritis) is chronic and can not be recovered. Pain becomes the main symptoms of osteoarthritis joints experience. The pain can disrupt motor function, sleep disorders and psychological stress. Nowadays, the treatment for elderly with osteoarthritis pain therapy is to pharmacotherapy. Due to psychological disorders such as anxiety and depression play a role in the recurrence of pain, then there is a complementary therapy intervention that is self-hypnosis. Self-hypnosis (as a complementary therapy) popular and familiar because it is easy to do, inexpensive and can be done at home independently. The aimed of this study was to find out whether there is any influence of self-hypnosis on the pain intensity and level of anxiety elderly with osteoarthritis.This study was a quantitative research in the form of quasi experimental randomized pretest-posttest control group design, intervention module using self-hypnosis to reduce pain intensity and level of anxiety elderly with osteoarthritis. This study was approved by the hospital ethics committee. The result of this study was a significant difference in the value pretest and posttest group treated osteoarthritis pain and anxiety elderly. The mean value of NRS (pain) treatment group pretest posttest 1,47 ± 0.57 and 0.97 ± 0.72 with p = 0.001> 0.05. The mean value of TMAS (anxiety) treatment group pretest amounted to 13.13 ± 2.27 posttest 10.93 ± 3.35 with p= 0.000Keywords: Self-Hypnosis, Pain Intensity, Level Of Anxiety, The Elderly With Osteoarthritis.

scholarly journals Peningkatan Pengetahuan Ibu-Ibu Rumah Tangga Dalam Perilaku Pengobatan Sendiri Untuk Penatalaksanaan Demam Dengan Metode Cara Belajar Ibu Aktif

2018 ◽  
Vol 1 (1) ◽  
pp. 27-30
Author(s):  
Rezqi Handayani
Keyword(s):  
Treatment Group ◽  
Mean Value ◽  
Pharmacological Therapy ◽  
Control Group ◽  
Test Results ◽  
Self Medication ◽  
Treatment Groups ◽  
Significant Difference ◽  
Level Of Knowledge ◽  
The Mean

Pharmacological therapy in fever patients is to provide Antipyretic drugs, can be done by using a doctor's prescription or by self-treatment. The condition that occurs in the community is self-medication conducted in the category of irrational treatment therapy because it is not in accordance with the condition of the patient. So, it is necessary to do education using Active Mother�s Ways of Learning Method to the housewives about rational fever self-treatment. The sample in this study were 40 housewives in the Flamboyant Bawah, divided into two major groups namely the control and treatment groups. Each group was given a pretest and posttest in a questionnaire of fever management. In the treatment group, fever drug education given before posttest by used CBIA method. The results showed an increase in knowledge of housewives from before education and after education was seen from the acquisition of grades. The mean pretest value in the control group was 74.38 and the treatment group was 69.69. Statistical test results show there was no significant difference in the mean value between the control group and the treatment group. The mean posttest value in the control group was 77.81 and the treatment group was 87.50. There was a significant difference between the mean value of the control group and treatment group. From the results of the statistical analysis showed that the level of knowledge of the treatment group given education by used the CBIA method produced a higher value than the control group that was not given education.

scholarly journals Effects of alfaprostol and luprostiol on the embryo production within MOET technique in Black Bengal goats

1970 ◽  
Vol 2 (2) ◽  
pp. 147-150 ◽  
Author(s):  
MI Faruk ◽  
BZ Fatema ◽  
FY Bari ◽  
MGS Alam
Keyword(s):  
Treatment Group ◽  
Embryo Transfer ◽  
Treated Group ◽  
Embryo Production ◽  
Recovery Method ◽  
Treatment Groups ◽  
Multiple Ovulation ◽  
Significant Difference ◽  
Surgical Recovery ◽  
The Mean

The effects of Alfaprostol and Luprostiol on embryo production within multiple ovulation and embryo transfer (MOET) technique were studied on 16 Black Bengal goats during the period from January 2002 to June 2003. These 16 goats were randomly divided into two equal groups (A & B), each consisting of 8 goats. Each of the 16 goats was flushed in different times within MOET technique to determine the effects of alfaprostol and luprostiol on embryo production. Each group consisting of 8 donors was synchronized with alfaprostol (Gabbrostim®, VETEM, Italy) or luprostiol (Prosolvin®, Intervet International, Netherlands) @ 2 mg and 7.5 mg, equivalent to 1 ml / donor respectively. The donor goats were hand mated following the onset of oestrus, 1-2 times at 6 h interval depending on the duration of oestrus. The embryos were collected at Day 7 of mating using surgical recovery method. The mean number of ovulation in alfaprostol and luprostiol group was 8.50 ± 0.90 and 8.1 ± 0.76, respectively, where in both cases 900 iu PMSG was used for induction. There was no significant (p > 0.05) difference between this two groups on superovulation rate. The mean numbers of recovered, fertilized and transferable embryos were 5.4 ± 0.80 and 5.1 ± 0.61; 3.9 ± 0.52 and 2.6 ± 0.37 and 3.6 ± 1.6 and 2.4 ± 1.0, respectively, in alfaprostol and luprostiol treatment group. Like superovulation, there was no difference between the two treatment groups on recovered, fertilized and transferable embryos. The percentage of recovered, fertilized and transferable embryos were 63 ± 7.7 and 63 ± 3.74, 72 ± 4.55 and 51 ± 7.0 and 93.6 ± 1.6 and 90.48 ± 1.0 in alfaprostol and luprostiol treated groups, respectively. The significant difference was only existed in the percentages of fertilized embryos between the two treatment groups, where alfaprostol treated group had the significantly (p < 0.01) higher percentage of fertilized embryos.Key words: Alfaprostol; luprostiol; effect; embryo transfer; ovulation; Black Bengal goatsdoi: 10.3329/bjvm.v2i2.2558Bangl. J. Vet. Med. (2004). 2 (2): 147-150

scholarly journals Standardization of Honey Application on Acute Partial Thickness Wound

1970 ◽  
Vol 1 (6) ◽  
Author(s):  
Benni Raymond ◽  
Gentur Sudjatmiko
Keyword(s):  
Clinical Trial ◽  
Wound Healing ◽  
Treatment Group ◽  
Control Group ◽  
Wound Treatment ◽  
Randomize Clinical Trial ◽  
Area Reduction ◽  
Partial Thickness ◽  
Significant Difference ◽  
The Mean

Backgrounds: : Inthe past few years, clinicians worldwide have been using honey for wound treatment. But until now, there was no such standard on method of honey application on wound. In our center, honey was applied on wound by once a day application and the result was observationally satisfactory. What if application of honey were done once every two days? Would the result become more satisfactory? This study aims to search honey application method, which gives the best result on wound treatment. Methods: This is single-blinded non-randomize clinical trial, which was conduscted in Cipto Mangunkusumo Hospital Jakarta from July until September 2012. 14 Patients with acute partial thickness wound resulted from STSG harvesting were involved in this study. Patients were devided into 2 groups: control (once every two days application of honey) and the rate of wound healing were evaluated. Rate of wound healing will be assessed as number of percentage of reduced non-epithelialized areas on the seventh day of application. Results: The mean percentage of non-epithelialized area reduction on treatment gruop was 86,76% and 97,97% on control group. There was significant difference on percentage of reduced area between control and treatment group (p<0,00). Conclusion: There was statistically signi!cant difference between once a day and once every two days application of honey. However, changing of honey dressing once a day is still a preferable method in wound treatment.

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