scholarly journals Interrelationship between vitamin A, iodine and iron status in schoolchildren in Shoa Region, Central Ethiopia

1993 ◽  
Vol 70 (2) ◽  
pp. 593-607 ◽  
Author(s):  
Zewdie Wolde-Gebriel ◽  
Clive E. West ◽  
Haile Gebru ◽  
Amha-Selassie Tadesse ◽  
Tezera Fisseha ◽  
...  

A total of 14740 schoolchildren in seven provinces of Shoa Administrative Region in Central Ethiopia were surveyed for the prevalence of goitre, xerophthalmia and anaemia. Haemoglobin and packed cell volume were assessed in 966 children in one province while an in-depth study was conducted on 344 children in the same province and two others. Goitre, xerophthalmia (Bitot's spots) and clinical anaemia were observed in 34·2, 0·91 and 18·6% respectively of the children. Most biochemical variables were within the normal range while those of haemoglobin (Hb), mean corpuscular Hb concentration (MCHC) and urinary I excretion were lower, and mean corpuscular volume, mean corpuscular Hb (MCH), and immunoglobulins G and M were higher. Hb was strongly correlated with retinol. ferritin, MCHC, MCH, packed cell volume and erythrocyte count while retinol formed a triad with transthyretin (TTR) and retinol-binding protein (RBP) which were all correlated with one another. Total and free thyroxin and total and free triiodothyronine were positively correlated as were the concentrations of the total and free hormones. Thyrotropin (TSH) was negatively correlated with total and free thyroxin and positively correlated with free triiodothyronine. Thyroxin and triiodothyronine in both free and combined forms were all correlated with thyroxin-binding globulin which in turn was negatively correlated with the triad retinol, RBP and TTR. The triad was also negatively correlated with C-reactive protein. Urinary I excretion was positively associated with total thyroxin and negatively associated with TSH. The anaemia found was not nutritional in origin but due to the effect of infestation with intestinal parasites and malaria.

2021 ◽  
Vol 14 (1) ◽  
pp. 97-103
Author(s):  
S. M. Tanjil Shah ◽  
Md. Tanvir Islam ◽  
Rakiba Zabin ◽  
Pravas Chandra Roy ◽  
Nigar Sultana Meghla ◽  
...  

Background and Aim: The use of antibiotic growth promoters (AGPs) in the poultry industry has raised concern because of their potential harm to human health. Emerging evidence suggests that probiotics are a safer substitute, although little research has explored this in Bangladesh. We recently isolated local bacterial strains with probiotic properties. We aimed to determine their impact on the growth, hematobiochemical parameters, and production costs of broiler chicks relative to that of a commercial probiotic (CP) and AGP. Materials and Methods: Day-old male broiler chicks (Cobb 500, n=63) were divided equally into three experimental groups (three replicates per group and seven chicks per replicate). First group was fed a basal diet supplemented with the AGP, ciprofloxacin (CTL group), second group was fed a basal diet supplemented with the CP, Protexin® (CP group), and the third group was fed a basal diet supplemented with our isolated bacterial strains (study probiotic [SP] group) for 36 days. Body weight was recorded daily, and relative growth rate (RGR), feed conversion ratio (FCR), and organ weights and carcass yields were calculated at the study's end. Blood obtained on day 36 was used to determine the number of red blood cell (RBC) and white blood cells (WBCs), hemoglobin (Hb) concentration, packed cell volume, erythrocyte sedimentation rate, as well as levels of serum glucose, total and high-density lipoprotein (HDL) cholesterol, and triglycerides (TGs). Total production costs were estimated by summing the variable and fixed costs. Results: Chicks in both the CP and SP groups experienced significant decreases in blood glucose levels and significant increases in BW, RGR, FCR, levels of RBC and WBC, Hb concentration, and packed cell volume compared with those in the CTL group (p<0.05 for all). Our data suggested a numerical reduction (p>0.05) in levels of total cholesterol, TGs, and HDL in the SP and CP groups when compared to the CTL group. In addition, both CP and SP treatments resulted in significant (p<0.05) gains in net profit compared with the treatment given to the CTL group. Conclusion: Administration of probiotics, either from a commercialized or local source, led to greater improvements in growth, hematological parameters, and net profits of broiler chicks when compared with that of an AGP. This suggests that they are suitable alternatives to the AGPs used in poultry feed and that our isolated strains, in particular, are an ideal option for farmers in Bangladesh.


1970 ◽  
Vol 2 (2) ◽  
pp. 125-127
Author(s):  
MMR Howlader ◽  
S Begum ◽  
KhN Islam ◽  
MA Hai ◽  
MG Hossain

The changes on packed cell volume (PCV) and haemoglobin (Hb) in zebu cattle infected with Fasciola gigantica were studied in two age and two season groups during the period from November 1999 to June 2000. Eighty-eight selected cattle were divided into two age groups, 2.5 to 5.5 years (n = 44; 22 infected & 22 uninfected control) and 6.0 to 9.0 years (n = 44; 22 + 22 cattle), and similarly two seasons, winter (n = 22 + 22) and summer (n = 22 + 22) were used for this study. Blood samples were collected in glass vials contained EDTA anticoagulant for each age group of all animals in summer and winter seasons. PCV was determined using microhematocrit and Hb concentration by cyanomethemoglobin methods. The PCV of F. gigantica infected cattle were significantly (p < 0.01) lower than the non-infected control animals. The average PCV obtained were 24.43% and 32.33% for F. gigantica infected and non-infected cattle, respectively. The Hb concentrations of infected cattle were significantly (p < 0.01) lower than the non-infected control animals. The average Hb values found were 7.59 and 10.13 g% for F. gigantica infected and noninfected cattle, respectively. There was no significant effect of age and season on the values of PCV and Hb concentrations in infected and non-infected cattle.Key words: Zebu cattle; Fasciola gigantica; packed cell volume; haemoglobin concentrationdoi: 10.3329/bjvm.v2i2.2553Bangl. J. Vet. Med. (2004). 2 (2): 125-127


Author(s):  
Ifebajo A.Y ◽  
Afolabi W.A.O ◽  
Sanni S.A ◽  
Onabanjo O.O ◽  
Ariyo A.M

Iron is essential for children's cognition because it enhances behavioural and intellectual performance and promotes the body's resistance to infections. However, the risk of iron deficiency increases during period of rapid growth notably among school aged children in developing countries. This study assessed the anthropometric and iron status of school children in Somolu Local Government Area of Lagos State. Somolu Local Government was selected using purposive sampling. One hundred and forty school children (8-12 years) were selected from 3 primary schools using multistage sampling technique. Socio economic data were collected using structured questionnaire. Nutritional status of pupils were assessed using anthropometric measurements while iron status was determined using biochemical analyses of serum ferritin (SF), packed cell volume (PCV) and haemoglobin (H-B). Socio economic data were analysed with descriptive statistic (frequency, mean and percentages). While Chi-square and Pearson product moment correlation were used to establish relationship between variables. Pattern of dietary iron sources intake of the respondents were determined using food frequency questionnaire. Result showed that mean values of weight, height, haemoglobin, packed cell volume and ferritin were 43.82kg, 141.67cm, 11.50g/dl, 33.91% and 49.10ng/l respectively. Results of Anthropometric assessment indicated that 18.2% of female and 12.7% male were stunted; 15.6% of female and 14.30% of male were wasted, while 27.3% of the female and 23.0% of the male were underweight. 67% of the subjects had normal ferritin (15-100ng/l), 19.0% had low ferritin (<15ng/l) while 14.3% had abnormal high ferritin (>100ng/l). The respondents (14.3%) whose ferritin level were exceedingly high (>100ng/l) belong to AC (4.7%), SC (3.5%), and SS (6.1%) genotype blood'groups. Findings also revealed that 24.2% of the male and 33.0% of female respondents were anaemic (Hb<11g/dl). 81.43% of the respondents consume less of iron rich food. The haemoglobinlevel of the male respondents were found to be positively correlated with their BMI. (r = 0.289, P > 0.05). There was a positive correlation between PCV and BMI of male respondents (r = 0.209., P < 0.05). Furthermore, there was a relationship between blood Ferriftin and genotype of both male and female respondents respectively (r = 0.276, P < 0.05), (r = 0.341, P < 0.05). A positive correlation existed between ferritin and food intake pattern of female respondents (r = 0.288, P < 0.05). There was a negative correlation between iron status and income of the respondents' parents, (r = 0.276, P < 0.05). In conclusion, this study has ascertained that there is stunting, wasting, underweight and iron deficiency among school children in Somolu Local Government Area of Lagos State. It is recommended that appropriate intervention should be introduced to reduce the prevalence of iron deficiency among school aged children in Somolu Local Government Area.


Author(s):  
Iserhienrhien Lucky Osafanme ◽  
Sheneni Victor Duniya ◽  
Nweje-Anyalowu Paul Chukwuemeka ◽  
Oguche Mercy ◽  
Idakwoji Precious Adejoh

Aim: The haematinic activity of the aqueous extract of Lophira lanceolata leaves was investigated using rat model of phenylhydrazine-induced anaemia. Methods and Results: Red Blood Cell (RBC) count, Haemoglobin (Hb) concentration and Packed Cell Volume (PCV) were analysed as indices of anaemia. Following phenylhydrazine administration to rats at a dose of 10 mg/kg for 8 days, a significant decrease (P<0.05) in the haematological parameters was observed indicating anaemia. However, treatment with graded doses (200, 400 and 800 mg/kg) of the aqueous extract of Lophira lanceolata leaves produced a significant (P<0.05) increase in the RBC count, Hb concentration and PCV time- and dose- dependently. Conclusion: It was concluded that Lophira lanceolata leaves possess haematinic activity, making it useful in the management of anaemia.


Author(s):  
AY Ifebajo ◽  
WAO Afolabi ◽  
SA Sanni ◽  
OO Onabanjo ◽  
AM Ariyo

Iron is essential for children's cognition because it enhances behavioural and intellectual performance and promotes the body's resistance to infections. However, the risk of iron deficiency increases during period of rapid growth notably among school aged children in developing countries. This study assessed the anthropometric and iron status of school children in Somolu Local Government Area of Lagos State. Somolu Local Government was selected using purposive sampling. One hundred and forty school children (8-12 years) were selected from 3 primary schools using multistage sampling technique. Socio economic data were collected using structured questionnaire. Nutritional status of pupils were assessed using anthropometric measurements while iron status was determined using biochemical analyses of serum ferritin (SF), packed cell volume (PCV) and haemoglobin (H-B). Socio economic data were analysed with descriptive statistic (frequency, mean and percentages). While Chi-square and Pearson product moment correlation were used to establish relationship between variables. Pattern of dietary iron sources intake of the respondents were determined using food frequency questionnaire. Result showed that mean values of weight, height, haemoglobin, packed cell volume and ferritin were 43.82kg, 141.67cm, 11.50g/dl, 33.91% and 49.10ng/l respectively. Results of Anthropometric assessment indicated that 18.2% of female and 12.7% male were stunted; 15.6% of female and 14.30% of male were wasted, while 27.3% of the female and 23.0% of the male were underweight. 67% of the subjects had normal ferritin (15-100ng/l), 19.0% had low ferritin (<15ng/l) while 14.3% had abnormal high ferritin (>100ng/l). The respondents (14.3%) whose ferritin level were exceedingly high (>100ng/l) belong to AC (4.7%), SC (3.5%), and SS (6.1%) genotype blood groups. Findings also revealed that 24.2% of the male and 33.0% of female respondents were anaemic (Hb <11g/dl). 81.43% of the respondents consume less of iron rich food. The haemoglobin levels of the male respondents were found to be positively correlated with their BMI. (r = 0.289, P > 0.05). There was a positive correlation between PCV and BMI of male respondents (r = 0.209., P < 0.05). Furthermore, there was a relationship between blood Ferriftin and genotype of both male and female respondents respectively (r = 0.276, P < 0.05), (r = 0.341, P < 0.05). A positive correlation existed between ferritin and food intake pattern of female respondents (r = 0.288, P < 0.05). There was a negative correlation between iron status and income of the respondents' parents, (r = 0.276, P < 0.05). In conclusion, this study has ascertained that there is stunting, wasting, underweight and iron deficiency among school children in Somolu Local Government Area of Lagos State. It is recommended that appropriate intervention should be introduced to reduce the prevalence of iron deficiency among school aged children in Somolu Local Government Area.


2005 ◽  
Vol 29 (1) ◽  
pp. 76-81
Author(s):  
A. M.H . Al-Judi

The effect of vit.E in feed blocks to ewes were studied in ewes on thefollowing parameters; Hemoglobin concentration, Packed Cell Volume,differential leukocytic count, total protein, albumin, and globulin ratios. Therewere a significant decrease in Hb concentration & PCV after two,& four weeks,there were no significant differences in the percentage of lymphocytes,neutrophils,& eiosinophils, & with a significant increase in monocytepercentage.There was no significant different in total protein ratio, while the ratio ofalbumin decreased significantly after 2 & 4 weeks, with a significant increase inthe globulin ratio at the same period.


Author(s):  
Paa-Kobina Turkson ◽  
Ebenezer Y. Ganyo

A convention that has been adopted in medicine is to estimate haemoglobin (HB) concentration as a third of packed cell volume (PCV) or vice versa. The present research set out to determine whether a proportional relationship exists between PCV and Hb concentration in cattle blood samples, and to assess the validity of the convention of estimating Hb concentration as a third of PCV. A total of 440 cattle in Ghana from four breeds (Ndama, 110; West African Short Horn, 110; Zebu, 110 and Sanga, 110) were bled for haematological analysis, specifically packed cell volume, using the microhaematocrit technique and haemoglobin concentration using the cyanmethaemoglobin method. Means, standard deviations, standard errors of mean and 95% confidence intervals were calculated. Trendline analyses generated linear regression equations from scatterplots. For all the cattle, a significant and consistent relationship (r = 0.74) was found between Hb concentration and PCV (%). This was expressed as Hb concentration (g/dL) = 0.28 PCV + 3.11. When the Hb concentration was estimated by calculating it as a third of PCV, the relationship was expressed in linear regression as Hb concentration (g/dL) = 0.83 calculated Hb + 3.11. The difference in the means of determined (12.2 g/dL) and calculated (10.9 g/dL) Hb concentrations for all cattle was significant (p < 0.001), whereas the difference in the means of determined Hb and corrected calculated Hb was not significant. In conclusion, a simplified relationship of Hb (g/dL) = (0.3 PCV) + 3 may provide a better estimate of Hb concentration from the PCV of cattle.


Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2340
Author(s):  
Jordie A. J. Fischer ◽  
Carolina S. Sasai ◽  
Crystal D. Karakochuk

Oral contraceptive use has been associated with decreased menstrual blood losses; thus, can independently reduce the risk of anemia and iron deficiency in women. Manufacturers have recently started to include supplemental iron in the non-hormonal placebo tablets of some contraceptives. The aims of this narrative review are: (i) to describe the relationship between oral contraceptive use and both anemia and iron status in women; (ii) to describe the current formulations of iron-containing oral contraceptives (ICOC) available on the market; and (iii) to systematically review the existing literature on the effect of ICOC on biomarkers of anemia and iron status in women. We discovered 21 brands of ICOC, most commonly including 25 mg elemental iron as ferrous fumarate, for seven days, per monthly tablet package. Our search identified one randomized trial evaluating the effectiveness of ICOC use compared to two non-ICOC on increasing hemoglobin (Hb) and iron status biomarker concentrations in women; whereafter 12 months of contraception use, there were no significant differences in Hb concentration nor markers of iron status between the groups. ICOC has the potential to be a cost-effective solution to address both family planning needs and iron deficiency anemia. Yet, more rigorous trials evaluating the effectiveness of ICOC on improving markers of anemia and iron deficiency, as well as investigating the safety of its consumption among iron-replete populations, are warranted.


Biomarkers ◽  
2006 ◽  
Vol 11 (4) ◽  
pp. 370-382 ◽  
Author(s):  
W. K. Al-Delaimy ◽  
E. H. J. M. Jansen ◽  
P. H. M. Peeters ◽  
J. D. van der Laan ◽  
P. A. H. van Noord ◽  
...  

2005 ◽  
Vol 41 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Jennifer L. Strasser ◽  
Eleanor C. Hawkins

Epistaxis was retrospectively evaluated in 35 dogs. Systemic disease was diagnosed in seven dogs and intranasal disease in 29. Nineteen dogs with intranasal disease had neoplasia. Dogs with neoplasia were older (mean 10.0 years) than dogs with nonneoplastic intranasal disease (mean 5.6 years). Signs persisting for &gt;1 month occurred more often in dogs with intranasal than systemic disease. Unilateral epistaxis did not distinguish intranasal from systemic disease. Only dogs with intranasal disease had facial deformity, decreased airflow, or regional sub-mandibular lymphadenopathy. Dogs with systemic disease had a lower packed cell volume (mean 31.8%) than dogs with intranasal disease (mean 42.7%).


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