Oral Cancer - Results of Treatment in the Copenhagen University Hospital

2000 ◽  
Vol 120 (543) ◽  
pp. 246-247 ◽  
Author(s):  
Birgitte Charabi
Keyword(s):  
Oral Cancer ◽  
University Hospital ◽  
Results Of Treatment

CLINICAL AND PARACLINICAL CHARACTERISTICS AND RESULTS FROM TREATMENT OF FOREIGN BODIES INGESTION

2016 ◽  
pp. 63-69
Author(s):  
Hoang Cuong Vo ◽  
Thanh Dang ◽  
Phuong Nam Tran ◽  
Thanh Thai Le
Keyword(s):  
Foreign Body ◽  
Clinical Characteristics ◽  
Foreign Bodies ◽  
University Hospital ◽  
Age Group ◽  
Central Hospital ◽  
Results Of Treatment ◽  
Rigid Esophagoscopy ◽  
Flexible Esophagoscopy ◽  
Esophageal Foreign Bodies

Background: Foreign bodies ingestion is a emergency in otology, knowledge of people about foreign bodies ingestion is not enough. Objective: To study the clinical characteristics, paraclinical characteristics and results of treatment from foreign bodies ingestion in Hue Central Hospital and Hue University Hospital. Methods and patiens: A cross descriptive and prospective study over the period from 6/2014 to 5/2016, total are 137 patients come to be diagnosised and treatmented. Results: the average age is 35 years old. Gender: male (51.8%) and women (48.2%). Adults (84.7%) having more than children (15.3%). Age group from 16-30 years is highest (32.8%). There are 95.7% of organic foreign bodies, 4.3% are inorganic foreign bodies. There are 90.5% of patients on diagnosis and treatment in stages less inflammation, arthritis 8.0% in the period and 1.5% in the period complications. Foreign body in the throat problems (73.7%), esophageal foreign bodies (26.3%). Pick up directly foreign bodies 54%, indirectly by the mirror 11.7% and endoscopy 8%, rigid esophagoscopy is 17.5%, flexible esophagoscopy is 7.3%, cervicotomy is 1.5%. Conclusion: Practing direction with in the oropharynx foreign body, using the larynx mirror or endoscopy with in the laryngopharynx for the esophagus foreign bodies, rigid esophagoscopy is better. Key words: Foreign bodies ingestion

scholarly journals Extent of neck dissection for patients with clinical N1 oral cancer

2020 ◽  
Vol 25 (6) ◽  
pp. 1067-1071 ◽  
Author(s):  
Yasumasa Kakei ◽  
Hirokazu Komatsu ◽  
Tsutomu Minamikawa ◽  
Takumi Hasegawa ◽  
Masanori Teshima ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Cancer ◽  
Neck Dissection ◽  
Tongue Cancer ◽  
Positive Lymph Node ◽  
University Hospital ◽  
Oral Cancers ◽  
Node Metastasis ◽  
Level Ii

Abstract Background No clear consensus has been reached on the indication of supraomohyoid neck dissection (SOHND) for clinically positive lymph-node metastasis. Patients Consecutive 100 patients with previously untreated oral cancer treated at Kobe University Hospital were included in this study. All patients were clinically staged as anyTN1M0 and underwent radical dissection of the primary site and level I–V neck dissection as the initial treatment. Results None of the 100 patients had pathological lymph-node metastasis (pLN) to level V. pLN to level IV was observed in two patients with tongue cancer in whom clinical lymph-node metastasis was preoperatively observed at level II. Conclusions Level V may be excluded in the neck dissection for patients with N1 oral cancers. Level IV dissection should be considered in the patient with tongue cancer and clinical lymph-node metastasis at level II.

scholarly journals Epidemiology and cost analysis for patients with oral cancer in a university hospital in China

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Sheng Han ◽  
Yan Chen ◽  
Xu Ge ◽  
Ming Zhang ◽  
Jinwei Wang ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cost Analysis ◽  
University Hospital

CLINICAL CHARACTERISTICS, CLASSIFICATION AND RESULTS OF TREATMENT RECURRENT ANAL FISTULA

2019 ◽  
Author(s):  
Toulabouth Manothay ◽  
Doan Van Phu Nguyen
Keyword(s):  
Wound Healing ◽  
Surgical Treatment ◽  
Anal Fistula ◽  
Postoperative Hemorrhage ◽  
Healing Time ◽  
University Hospital ◽  
Fistula Tract ◽  
Cross Sectional ◽  
Recurrent Fistula ◽  
Results Of Treatment

Objectives: To evaluate the results of surgical treatment of recurrent anal fistula. Methods: This was a cross-sectional, descriptive study including 30 recurrent anal fistula patients who underwent surgery from March 2017 to August 2018 at Hue University Hospital of Medicine and Pharmacy and Hue Central Hospital. Results: Male/female radio was 4/1. The highest proportion was among the ages of 21 – 60 (90%). The most common clinical presentation was perianal discharge in 86.7% of cases. The average duration of disease was found to be 2.5 ± 1.7 months approximately. Early postoperative complications rate is. 36.7% including: air or facial incontinence (33.4%),,postoperative hemorrhage (3.s3%). Average wound healing time is 7.5 ± 2.3 weeks and delayed wound healing rate is 100%. Results of surgical treatment of recurrent fistula anal are good 90%, mid 6.7%, poor 3.3%. Conclusions: Surgical treatment of recurrent anal fistula must depend upon the understanding the relative between anal sphincter and fistula tract. Surgical procedures have to be suitable for each type of anal fistulas. Key words: anal fistula, recurrent, surgical treatment

scholarly journals Serum Natrium Determines Outcome of Treatment of Advanced GIST with Imatinib: A Retrospective Study of 80 Patients from a Single Institution

ISRN Oncology ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Ninna Aggerholm-Pedersen ◽  
Peter Rasmussen ◽  
Helle Dybdahl ◽  
Philip Rossen ◽  
Ole Steen Nielsen ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Kinase Inhibitors ◽  
University Hospital ◽  
Time To Progression ◽  
Single Institution ◽  
Multicenter Studies ◽  
First Line Therapy ◽  
Results Of Treatment ◽  
Line Therapy ◽  
Advanced Gist

Treatment with tyrosine kinase inhibitors (TKIs) has drastically improved overall survival (OS) of patients with advanced GIST. The aim of this study is to evaluate the results of treatment with different TKIs on advanced GIST and identify prognostic factors for OS. The medical records of all patients treated at the Department of Oncology, Aarhus University Hospital were retrospectively reviewed. Between 2001 and 2009, 80 patients with advanced GIST were treated with imatinib as first-line therapy. The median OS was 44 months (95% CI 31–56), and the 5-year OS was 40%. Since 2005, 32 patients were treated with sunitinib as 2nd-line therapy. The median time to progression was 9 months (95% CI: 3–13 months), and the 3-year OS was 30%. The data illustrate that data from large multicenter studies are reproducible in a single sarcoma centre. This retrospective study pointed to low serum sodium at the start of imatinib as a possible prognostic factor affecting OS.

Diagnostic Role of Saliva in Oral Cancers

2020 ◽  
Vol 71 (7) ◽  
pp. 474-480
Author(s):  
Radu Radulescu ◽  
Maria Greabu ◽  
Alexandra Totan ◽  
Marina Melescanu Imre ◽  
Daniela Miricescu ◽  
...  
Keyword(s):  
Oral Cancer ◽  
University Hospital ◽  
Oral Cancers ◽  
Facial Surgery ◽  
Biomarker Analysis ◽  
Diagnostic Role ◽  
Total Antioxidant ◽  
Almost All ◽  
Tumoral Cells

Saliva is a noninvasive diagnostic fluid alternative containing almost all the compounds found in blood, oral and tumoral cells. The aim of this study is to analyze the correlations occurred between different key biomarkers involved in different stages of oral cancer, such as inflammation markers - interleukin 6 (IL-6), extracellular collagen degradation markers - matrix metalloprotease 9 (MMP-9) and tissue inhibitors of metalloprotease 2 (TIMP-2).This study included a lot of 30 patients diagnosed with oral cancer at the Department of Oro Maxillo-Facial Surgery, University Hospital of Dental Medicine Prof. Dr. Dan Teodorescu. The patients were included in this study after informed consent was obtained. Salivary biomarker analysis was made using ELISA methods, biochemical or colorimetric assays. Uric acid (UA) levels were positively correlated with total antioxidant capacity (TAC) levels (r = 0.78). TAC levels were negatively correlated with IL-6 levels (r = -0.66). MMP-9 levels were positively correlated with the Ki-67protein (also known as MKI67) levels (r = 0.65) and negatively correlated with TIMP-2 levels (r = -0.71). We can conclude upon the results that salivary research may lead to the usage of saliva as a quick and reliable screening and diagnostic tool for oral cancer.

Volatile Organic Compounds in the Breath of Oral Squamous Cell Carcinoma Patients: A Pilot Study

2017 ◽  
Vol 157 (6) ◽  
pp. 981-987 ◽  
Author(s):  
Stefan Hartwig ◽  
Jan D. Raguse ◽  
Dorothee Pfitzner ◽  
Robert Preissner ◽  
Sebastian Paris ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Pilot Study ◽  
Volatile Organic Compounds ◽  
Oral Cancer ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Organic Compounds ◽  
Squamous Cell ◽  
University Hospital ◽  
Volatile Organic

Objective To assess the feasibility of detecting signature volatile organic compounds in the breath of patients with oral squamous cell carcinoma. Study Design Prospective cohort pilot study. Setting University hospital. Subjects and Methods Using gas chromatography and mass spectrometry, emitted volatile organic compounds in the breath of patients before and after curative surgery (n = 10) were compared with those of healthy subjects (n = 4). It was hypothesized that certain volatile organic compounds disappear after surgical therapy. A characteristic signature of these compounds for diseased patients was compiled and validated. Results Breath analyses revealed 125 volatile organic compounds in patients with oral cancer. A signature of 8 compounds that were characteristic for patients with oral cancer could be detected: 3 from this group presented were absent after surgery. Conclusion The presented results confirmed the hypothesis of an absence of cancer-associated volatile organic compounds in the breath after therapy. In this pilot study, we proved the feasibility of this test approach. Further studies should be initiated to establish protocols for usage in a clinical setting.

scholarly journals Oral Cancer Lethality in the Dental Department of Kinshasa University Hospital, Democratic Republic of the Congo

2021 ◽  
pp. 160-165
Author(s):  
Charly Mana Mfutu ◽  
Jean-Paul Isouradi Sekele ◽  
Fidèle Nyimi Bushabu ◽  
Adelin Baudouin Nzudjom Foche ◽  
Matthieu Nkumu Loposso ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Low Income ◽  
Cancer Mortality ◽  
Democratic Republic ◽  
Histological Type ◽  
University Hospital ◽  
Primary Role ◽  
Early Management ◽  
Cancer Management ◽  
Republic Of The Congo

Background: Despite the scientific advances achieved during this century in cancer management, nevertheless, the cancer disease remains one of the most fatal sickens globally and little data are available on oral cancer mortality in most low-income countries including the Democratic Republic of the Congo. Aim: To assess the frequency of oral cancer mortality in the Department of Dental medicine at the Kinshasa University Hospital. Patients and Methods: A cross-sectional study based on the records of patients who died from oral cancer was conducted in the Department of Dental Medicine, Kinshasa University Hospital spanning over a period of 20 years (2000 to 2019). The data were collected from the records of patients with a histologically proven diagnosis of cancer. Pertinent parameters included Age, sex, stage of disease, histological type of tumor and probability of survival of patients were evaluated. Results: During the study, 889 patients were hospitalized in the Department. Out of 91 patients who died while in hospital, 49 deaths (53.8%) were from oral cancer in 57% males. Median age was 46.02±19.6 years and sex ratio of male/female of 1.3. The epidermoid or squamous cell carcinoma (63.3%) was the most frequent histological type of malignancy, and the majority of deaths (96%) occurred at and advanced cT4NM clinical stage with 90% having less than 200 days prognostic survival chance. Conclusion: The frequency of lethality in the present study was high and constitutes a health problem concern in the Democratic Republic of Congo. This study emphasizes the primary role devoted to oral health professionals in education, population, prevention, early detection and early management of oral cancer.

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