scholarly journals Effectiveness of a Food-Based Intervention to Increase Breast Milk Vitamin A Content at One Month of Infancy

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 130-130
Author(s):  
Sumathi Swaminathan ◽  
Sumithra Selvam ◽  
Agnita Narendra ◽  
Tinku Thomas ◽  
Anil Vasudevan ◽  
...  
Keyword(s):  
Breast Milk ◽  
Vitamin A ◽  
Randomized Study ◽  
Beta Carotene ◽  
Maternal Blood ◽  
Energy Agency ◽  
Funding Sources ◽  
Deuterium Dilution ◽  
And Control ◽  
Β Carotene

Abstract Objectives Vitamin A requirements in early infancy are met only by breast milk intake. It is critical to ensure adequate breast milk vitamin A levels which also helps develop liver stores. The objective of the study was to evaluate the effect of a maternal food-based intervention on breast milk vitamin A content Methods Pregnant women (n = 50; 24 ± 1 week of gestation) were recruited for the randomized study. A 10 g of a green leafy vegetable powder (mint/coriander/curry) providing about 3200 μg β-carotene/day, for a period of 4 months up to 1 month of lactation were provided for intervention arm. Breast milk (BM) retinol concentration and BM volume were assessed. BM retinol and beta-carotene were assayed by HPLC and BM fat by creamatocrit method. BM retinol: fat ratio was calculated. The dose-to-mother deuterium dilution technique was used to estimate BM volume through enrichment of saliva measured by Fourier Transform Infrared Spectroscopy. Total BM retinol content was calculated from BM volume and the BM retinol (including beta-carotene:1 vitamin A RAE = 12 μg β-carotene). Inadequacy of intake was defined as proportion of infants with intake below a requirement of 400 μg RAE/day. Analysis of co-variance was performed after adjusting for age of mother, change in maternal blood retinol from baseline and BM fat, to compare outcomes between intervention and control arm. Results Maternal age, gestational age, socio-demographic characteristics and baseline vitamin A intake were comparable in both arms. Mean BM volume was similar in the 2 arms (676 ± 102 in intervention vs 630 ± 100 ml/day in control). BM retinol content (0.72 ± 0.12 vs 0.64 ± 0.11 μg/mL; P = 0.029) and BM retinol: fat ratio [0.41 (0.31, 0.47) vs 0.29 (0.21, 0.41), P = 0.011] were significantly higher in the intervention arm. The mean total BM retinol content was significantly higher in the intervention (482.2 ± 100.7 vs 406.5 ± 89.2 μg/day; P = 0.015; Cohen's effect size 0.80). Inadequacy of infant vitamin A intake was 14.3% in the intervention arm as against 39.1% in the control arm (P = 0.065). Conclusions The food-based intervention was effective in increasing vitamin A content in breast milk and thereby vitamin A intake in infants. Funding Sources International Atomic Energy Agency.

scholarly journals Analysis of βeta-carotene from Jongi (Dillenia Serrata Thunb.) as a source of vitamin A

2021 ◽  
Vol 10 (2) ◽  
pp. 184-190
Author(s):  
Khairun Nisa ◽  
Ryka Marina Walanda
Keyword(s):  
Chronic Disease ◽  
Vitamin A ◽  
Essential Role ◽  
Antioxidant Activities ◽  
Beta Carotene ◽  
Neurological Function ◽  
The Body ◽  
Yellow Orange ◽  
Β Carotene ◽  
Healthy Eyes

Beta-carotene is converted in the body to vitamin A, a powerful antioxidant that plays an essential role in maintaining healthy eyes, skin, and neurological function. Beta-carotene and other carotenoids have antioxidant activities and are valued for their ability to prevent chronic disease. β-carotene is found in yellow, orange, red, and green fruits. The purpose of this study was to determine the β-carotene in Jongi. Jongi (Dillenia Serrata Thunb.) is an endemic fruit of Sulawesi which contains β-carotene. The samples used in this study were raw jongi and ripe jongi extracted with n-hexane: acetone (1:4). To the samples were analyzed quantitatively using UV-Vis spectrophotometry at a wavelength of 450.00 nm. The results showed that the β-carotene in raw jongi was 0.3554 mg/100 g and the β- carotene in ripe jongi was 1.1841 mg/100 g. Ripe jongi consist of more β-carotene than the raw jongi, hence better as a source of Vitamin A.

scholarly journals Vitamin A intake of Brazilian mothers and retinol concentrations in maternal blood, human milk, and the umbilical cord

2018 ◽  
Vol 46 (4) ◽  
pp. 1555-1569 ◽  
Author(s):  
Thalia Manfrin Martins Deminice ◽  
Ivan Savioli Ferraz ◽  
Jacqueline Pontes Monteiro ◽  
Alceu Afonso Jordão ◽  
Lívia Maria Cordeiro Simões Ambrósio ◽  
...  
Keyword(s):  
Breast Milk ◽  
Vitamin A ◽  
Human Milk ◽  
Pregnant Women ◽  
Umbilical Cord ◽  
Maternal Blood ◽  
Maternal Serum ◽  
Serum Retinol ◽  
Cross Sectional ◽  
Blood Samples

Objectives To analyse intake of vitamin A (VA) and retinol concentrations in maternal blood, breast milk (BM), and the umbilical cord (UC) of newborns, and to determine the associations among these variables. Methods We performed a cross-sectional, epidemiological study of 180 mother–newborn dyads. Maternal and UC blood samples and BM were collected. VA intake by the mother over 30 days was assessed using a questionnaire. Results Mean retinol concentrations in maternal serum, the UC, and BM were 0.65 ± 0.27, 0.36 ± 0.18, and 2.95 ± 2.70 µmol/L, respectively. Retinol concentrations <0.70 µmol/L were found in 57.2% of maternal blood samples and in 94.9% of UC samples. A total of 27.9% of BM samples showed retinol concentrations <1.05 µmol/L. Mean VA intake by the mothers was 1041.33 ± 1187.86 µg retinol activity equivalents/day and was inadequate (<550 µg retinol activity equivalents/day) in 44.7%. Conclusions High proportions of insufficient retinol concentrations were observed in the UC, maternal blood, and BM. A high percentage of pregnant women had inadequate VA intake. Mothers with insufficient serum retinol concentrations had newborns with lower retinol concentrations in the UC. Higher retinol concentrations were observed in maternal blood and the UC with a higher VA intake.

scholarly journals Diallel Analysis of Sweet Potato [Ipomoea batatas (L.) Lam] Genotypes for Combined Beta Carotene and Dry Matter Content in Southern Guinea Savanna, Nigeria

2019 ◽  
pp. 1-9
Author(s):  
M. S. Afolabi ◽  
O. B. Bello ◽  
G. O. Agbowuro ◽  
C. O. Aremu ◽  
M. O. Akoroda
Keyword(s):  
Vitamin A ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Dry Matter ◽  
Vitamin A Deficiency ◽  
Beta Carotene ◽  
Matter Content ◽  
Quality Trait ◽  
Dry Matter Content ◽  
Β Carotene

Roots of orange-fleshed sweet potato varieties currently available in Nigeria contain high quantities of β-carotene or pro-vitamin A but have high moisture content. These varieties have been found to be a cheap and crucially important remedy for vitamin A deficiency. The cream or white-fleshed varieties, on the other hand, have a sweet taste with high dry matter content, giving a dry texture, a quality trait preferred in Nigeria. Development of sweet potato genotypes that can combine these two important quality traits is the objective of this breeding work. A diallel experiment using six parental sweet potato genotypes crossed in all possible combinations were carried out and thirty progenies were evaluated for beta carotene (β-carotene) and dry matter content in Landmark University, Omu Aran, Kwara State, Nigeria. The 30 F1 progenies along with their parental lines were planted in the same field trial. The trial was laid out in 6 x 6 triple lattice in two replications. Highly significant (P≤ 0.01) differences were observed among the genotypes for the traits. The average β-carotene content among the progenies was 2.86 (mg/100g.f.w) while the dry matter cttgontent had a mean value of 31.89%. The cross progenies 199024.2 x Excel had the highest beta carotene (14.37mg/100g.f.w) content with the highest dry matter content (40.10%) and are therefore recommended for further evaluation.

Combining Ability of Sweet Potato [Ipomoea batatas (L.) Lam] Genotypes for Beta Carotene and Dry Matter Content in Southern Guinea Savanna, Nigeria

2021 ◽  
Vol 19 (1) ◽  
pp. 53-61
Author(s):  
M.S Afolabi ◽  
G.O Agbowuro ◽  
A.E Salami ◽  
M.O Akoroda
Keyword(s):  
Vitamin A ◽  
Sweet Potato ◽  
Dry Matter ◽  
Beta Carotene ◽  
Diallel Analysis ◽  
Matter Content ◽  
Dry Matter Content ◽  
Carotene Content ◽  
Guinea Savanna ◽  
Β Carotene

Roots of orange fleshed sweet potato varieties currently available in Nigeria contain high quantities of β-carotene or pro-vitamin A but have high moisture content. These varieties have been found to be a cheap and important remedy for vitamin A deficiency. The cream or white fleshed varieties on the other hand, have sweet taste with high dry matter content, giving a dry texture, a quality trait preferred in Nigeria. The objectives of this study were to examine the quantitative inheritance of important traits in sweet potato by means of a diallel analysis with a view to estimating the GCA and SCA components of genetic variance, and to determine the associated type of gene action controlling β-carotene content and root dry mass. A diallel crosses experiment using six parental sweet potato genotypes crossed in all possible combinations were carried out. Resultant thirty progenies were evaluated for beta carotene (β-carotene) and dry matter content in Landmark University, Omu Aran, Kwara State, Nigeria during the cropping season of 2012 and 2013. The 30 F1 progenies along with their parental lines were planted in the same field trial. The trial was laid out in 6 x 6 triple lattice in two replications. Highly significant (P≤ 0.01) differences were observed among the genotypes for all the tested traits. The average β-carotene content for the progenies was 2.86 (mg/100 g f.w.) while the dry matter content was 31.89%. The cross combination 199024.2 x Excel recorded the highest beta carotene (14.37 mg/100 g f.w) and dry matter content (40.10%), this candidate is therefore suggested for further evaluation. Key words: Diallel analysis, Dry matter, Southern Guinea Savanna, Sweet potato, Vitamin A, β-carotene.

REPRODUCTIVE PERFORMANCE OF PREPUBERTAL DAIRY HEIFERS ON LOW OR HIGH β-CAROTENE DIETS

1987 ◽  
Vol 67 (2) ◽  
pp. 477-489
Author(s):  
F. R. TEKPETEY ◽  
W. M. PALMER ◽  
J. R. INGALLS
Keyword(s):  
Vitamin A ◽  
Estrous Cycle ◽  
Reproductive Performance ◽  
Average Daily Gain ◽  
Beta Carotene ◽  
Corn Silage ◽  
Dairy Heifers ◽  
Daily Gain ◽  
Estradiol 17Β ◽  
Β Carotene

Twenty 5-mo-old heifers were assigned randomly to either a no-carotene or a carotene-supplemented grain ration (2–2.5 kg head−1 d−1) for a 10-mo trial to investigate the effect of β-carotene deficiency on pre and postpuberal reproductive performance. All heifers received, ad libitum, a low-carotene basal forage of corn silage, weathered hay and/or straw. Mean serum β-carotene and vitamin A were higher (P < 0.05) in the carotene-supplemented heifers. Beta-carotene supplementation improved (P < 0.05) overall average daily gain, but had no effect on mean age and body weight at puberty, estrous cycle length and services per conception. Mean serum concentrations of progesterone (P4) estradiol-17β, LH and FSH from prepuberty to day 17 of the first estrous cycle were not affected by β-carotene supplementation. Total P4 output during the estrous cycle did not differ between control and β-carotene-supplemented heifers. However, intensity of estrus was weaker (P < 0.01) and interval (h) from LH peak to ovulation was longer (P < 0.01) in the control (low-carotene) heifers. Key words: β-carotene, vitamin A, reproductive performance, prepubertal dairy heifers

scholarly journals β-Cryptoxanthin from supplements or carotenoid-enhanced maize maintains liver vitamin A in Mongolian gerbils (Meriones unguiculatus) better than or equal to β-carotene supplements

2008 ◽  
Vol 100 (4) ◽  
pp. 786-793 ◽  
Author(s):  
Christopher Davis ◽  
Hua Jing ◽  
Julie A. Howe ◽  
Torbert Rocheford ◽  
Sherry A. Tanumihardjo
Keyword(s):  
Vitamin A ◽  
Cottonseed Oil ◽  
Meriones Unguiculatus ◽  
Mongolian Gerbils ◽  
Institute Of Medicine ◽  
Retinyl Acetate ◽  
Provitamin A Carotenoids ◽  
And Control ◽  
Β Carotene ◽  
Better Than

Maize with enhanced provitamin A carotenoids (biofortified), accomplished through conventional plant breeding, maintains vitamin A (VA) status in Mongolian gerbils (Meriones unguiculatus). Two studies in gerbils compared the VA value of β-cryptoxanthin with β-carotene. Study 1 (n 47) examined oil supplements and study 2 (n 46) used maize with enhanced β-cryptoxanthin and β-carotene. After 4 weeks' depletion, seven or six gerbils were killed; remaining gerbils were placed into weight-matched groups of 10. In study 1, daily supplements were cottonseed oil, and 35, 35 or 17·5 nmol VA (retinyl acetate), β-cryptoxanthin or β-carotene, respectively, for 3 weeks. In study 2, one group of gerbils was fed a 50 % biofortified maize diet which contained 2·9 nmol β-cryptoxanthin and 3·2 nmol β-carotene/g feed. Other groups were given equivalent β-carotene or VA supplements based on prior-day intake from the biofortified maize or oil only for 4 weeks. In study 1, liver retinol was higher in the VA (0·74 (sd 0·11) μmol) and β-cryptoxanthin (0·65 (sd 0·10) μmol) groups than in the β-carotene (0·49 (sd 0·13) μmol) and control (0·41 (sd 0·16) μmol) groups (P < 0·05). In study 2, the VA (1·17 (sd 0·19) μmol) and maize (0·71 (sd 0·18) μmol) groups had higher liver retinol than the control (0·42 (sd 0·16) μmol) group (P < 0·05), whereas the β-carotene (0·57 (sd 0·21) μmol) group did not. Bioconversion factors (i.e. 2·74 μg β-cryptoxanthin and 2·4 μg β-carotene equivalents in maize to 1 μg retinol) were lower than the Institute of Medicine values.

scholarly journals Pengaruh Pemberian Cookies Galohgor terhadap Kadar Vitamin A ASI Ibu Nifas

2020 ◽  
Vol 9 (3) ◽  
pp. 95-100
Author(s):  
Ibnu Malkan Bakhrul Ilmi ◽  
Rimbawan Rimbawan ◽  
Katrin Roosita ◽  
Zakiudin Munasir
Keyword(s):  
Experimental Design ◽  
Breast Milk ◽  
Vitamin A ◽  
Food Consumption ◽  
Intervention Group ◽  
Control Group ◽  
Milk Samples ◽  
Quasi Experimental ◽  
Postpartum Mothers ◽  
Β Carotene

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian cookies galohgor terhadap kadar β-karoten dan retinol ASI ibu nifas. Penelitian ini menggunakan quasi-experimental design yang terdiri atas dua kelompok, yaitu kelompok kontrol (n=9) dan kelompok intervensi (n=9). Kelompok intervensi diberikan cookies galohgor 4 keping ~ 40 g/ hari, sedangkan kelompok kontrol diberikan cookies dengan jumlah yang sama namun cookies tersebut tanpa penambahan galohgor. Pemberian cookies dilakukan selama 40 hari pascamelahirkan. Sampel ASI diambil pada hari ke-14 dan hari ke-40 untuk dianalisis kadar β-karoten dan retinol ASI. Analisis konsumsi pangan juga dilakukan bersamaan dengan pengambilan sampel ASI. Hasil penelitian ini menunjukkan tidak terdapat perbedaan pada kadar β-karoten dan retinol ASI antara kelompok kontrol dan intervensi, baik pada hari ke-14 maupun hari ke-40 pascamelahirkan (p>0,05), akan tetapi pemberian cookies galohgor relatif dapat mempertahankan kadar β-karoten ASI selama masa nifas. Oleh karena itu, penelitian ini menyimpulkan cookies galohgor dapat menjadi sumber β-karoten ASI.Effect of Galohgor Cookies on Vitamin A Content in Breast Milk of Postpartum MothersAbstractThis study was aimed to analyze the effect of galohgor cookies on β-carotene and retinol in breast milk of postpartum mothers. This study used quasi-experimental design consisting of two groups, the control group (n = 9) and the intervention group (n = 9). The intervention group was given galohgor cookies (4 pieces ~ 40 g / day), while the control group was given cookies without galohgor as many as the intervention group. Cookies were given for 40 days after giving birth. Breast milk samples were taken on the 14th day and 40th day to analyze β-carotene and retinol content in breast milk along with the interview of food consumption. The results showed β-carotene and retinol content in breast milk did not differ significantly between the groups, both on the 14th day and the 40th day after giving birth (p>0.05). However, galohgor might maintain the β-carotene concentration in breast milk. Therefore, as conclusion, galohgor cookies may be provided as the source of β-carotene in breast milk.

scholarly journals Dietary Intervention to Control Vitamin A Deficiency in Seven- to Twelve-Year-Old Children

1994 ◽  
Vol 15 (1) ◽  
pp. 1-4 ◽  
Author(s):  
A. Wadhwa ◽  
A. Singh ◽  
A. Mittal ◽  
S. Sharma
Keyword(s):  
Vitamin A ◽  
Nutrition Education ◽  
Dietary Intervention ◽  
Vitamin A Deficiency ◽  
Serum Vitamin ◽  
Intervention Period ◽  
Intervention Programme ◽  
Significant Difference ◽  
And Control ◽  
Β Carotene

The efficacy of a dietary intervention programme to control vitamin A deficiency through inexpensive, locally available sources of β-carotene was evaluated in 121 children 7–12 years old. The subjects were randomly divided into experimental and control groups. A three-day food intake was first recorded for each subject using a 24-hour recall method and repeated at the end of the study on a randomly selected subsample. The intervention period lasted one month, during which carrots, papayas, coriander, and mint were offered daily as sources of β-carotene. There was no significant difference in the dietary intakes of the groups before the study. After the intervention period, the serum vitamin A values of the experimental subjects were significantly higher than those of the controls. These results indicate that consumption of small amounts of inexpensive, readily available vegetable sources of β-carotene could help prevent and control vitamin A deficiency. Nutrition education programmes are needed to encourage the use of these foods for home consumption as well as in feeding programmes for schoolchildren.

scholarly journals Contribution of Amaranthus cruentus and Solanum macrocarpon Leaves Flour to Nutrient Intake and Effect on Nutritional Status of Rural School Children in Volta Region, Ghana

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Godfred Egbi ◽  
Mary Glover-Amengor ◽  
Margaret M. Tohouenou ◽  
Francis Zotor
Keyword(s):  
Vitamin A ◽  
Nutritional Status ◽  
School Children ◽  
Intervention Group ◽  
Beta Carotene ◽  
Control Groups ◽  
Amaranthus Cruentus ◽  
Feeding Program ◽  
The Mean ◽  
And Control

Background. Plant-based foods are staple diets and main micronutrient sources of most rural Ghanaian households. The objective of this study was to determine the effect of Amaranthus cruentus and Solanum macrocarpon leafy vegetable flour on micronutrient intake and nutritional status of rural Ghanaian school children. Method. This study was a randomized controlled trial that consisted of baseline data collection and a three-month nutrition intervention feeding program. Two groups of 53 children, age 4–9 years, involved in the Ghana School Feeding Program took part in the study. An experimental group consumed Amaranthus cruentus and Solanum macrocarpon leaves flour (ACSMLVF) stews and soup. The control group consumed stews and soup without ACSMLVF. Haemoglobin and serum vitamin A concentrations were determined. Dietary and anthropometric data were collected and analysed. Participants were screened for malaria parasitaemia and hookworm. Results. Anaemia was present in 41.5% and 37.3%, respectively, of the intervention and control groups at baseline. It was present in 28.3% and 53.3%, respectively, at the end of the study. This was significantly different (p=0.024). There was a low vitamin A concentration in 66.0% and 64.7% at baseline and 20.8% and 23.4% at the end of the study in the intervention and control groups, respectively. The mean iron, zinc, and provitamin A (beta-carotene) intakes of the intervention group were 14.2 ± 7.1 mg, 5.7 ± 2.1 mg, and 214.5 ± 22.6 μg, respectively, at baseline. Those of the control were 13.7 ± 6.1 mg, 5.4 ± 2.1 mg, and 210.6 ± 20.1 μg, respectively. At the end of the study, the mean intake of iron, zinc, and beta-carotene for the intervention group was 24.1 ± 10.9 mg, 13.8 ± 8.2 mg, and 694.2 ± 33.1 μg, respectively. The intake of these micronutrients for the control at the end of the study was 14.8 ± 6.2 mg, 5.9 ± 2.3 mg, and 418.4 ± 34.7 μg, respectively. Conclusion. Consumption of ACSMLVF stews and soup increased iron, zinc, and beta-carotene intakes. Anaemia prevalence was lower in the intervention group at the end of the study.

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