scholarly journals Agreement Between Venous and Capillary Haemoglobin Concentrations in Bangladeshi Children (P10-105-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Leila Larson ◽  
Mohammed Imrul Hasan ◽  
Sabine Braat ◽  
Andrew Baldi ◽  
Mohammad Saiful Alam ◽  
...  
Keyword(s):  
Preliminary Data ◽  
Iron Supplementation ◽  
Correlation Coefficients ◽  
Kappa Coefficient ◽  
Capillary Blood ◽  
Altman Plot ◽  
Blood Samples ◽  
Bland Altman Plot ◽  
Funding Sources ◽  
Global Estimates

Abstract Objectives There are concerns that capillary haemoglobin (Hb) concentrations do not agree with venous Hb, which has implications for global estimates of anaemia largely derived from capillary Hb. In children enrolled in the Benefits and Risks of Iron Supplementation in Children (BRISC) trial, we examined differences between Hb concentrations collected from venous and capillary blood samples, and predictors of these differences. Methods Hb concentrations were measured in 3300 children at 8 months of age. Capillary Hb concentrations were measured during screening of children for inclusion in the trial. Venous Hb was measured up to 10 days after screening, during enrolment. All Hb measurements used the HemoCue® 301. In children who received both capillary and venous measurements, Hb means, standard deviations, and anaemia prevalence statistics were derived. Paired t-tests were used to compare means across groups. Pearson's correlation coefficients and a Bland-Altman plot were used to examine agreement between capillary and venous Hb. A kappa coefficient was used to examine agreement in diagnosis of anaemia between the two methods. Lastly, differences in mean venous and capillary Hb concentrations between phlebotomists were calculated using ANOVA. Results All 3300 children will have completed baseline Hb measurements by February 2019. The current abstract presents preliminary data up to December 2018 for 2485 children. Venous and capillary Hb concentrations were moderately correlated (r = 0.62). Prevalence of anaemia using venous samples was 44.8% and using capillary samples was 69.5%. Accounting for chance, the % agreement (kappa coefficient) between the methods for diagnosis of anaemia was 34.8%. Mean Hb concentrations were significantly higher in venous than capillary samples (mean ± SD: 11.0 ± 1.0 vs 10.4 ± 1.0 g/dL, P < 0.001). This is confirmed in the Bland-Altman plot. No differences in Hb were observed between phlebotomists. Conclusions Significant differences exist in the diagnosis of anaemia using capillary vs venous samples. Capillary Hb measurements should not be used as a surrogate for venous Hb as they may incorrectly estimate the prevalence of anaemia. Results indicated that global estimates of anaemia based on capillary Hb may be misrepresenting true estimates. Funding Sources NHMRC.

P1474Simpsons Triplane versus Biplane for left ventricle ejection fraction after myocardial infarction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
D Bras ◽  
C Reis ◽  
M J Andrade ◽  
R Ribeiras ◽  
M Mendes
Keyword(s):  
Myocardial Infarction ◽  
Ejection Fraction ◽  
Past History ◽  
Three Dimensional ◽  
Correlation Coefficients ◽  
Reference Method ◽  
Patient Characteristics ◽  
Anterior Wall ◽  
Altman Plot ◽  
Bland Altman Plot

Abstract Introduction Simpson's biplane (SBP) ignores the apical long-axis plane. It is estimated that 40% of myocardial infarction (MI)-related segmental abnormalities are located in this plane. The real-time triplane (RT3P) overcomes this issue, allowing to obtain all apical views simultaneously, at the same cardiac cycle. This method could be a more precise and reliable alternative to SBP in ejection fraction (EF) quantification in this setting. Purpose The authors aimed to compare EF assessed by two quantification methods, SBP and RT3P, using quantitative three-dimensional echocardiography (3DE) as the reference method, in patients with MI. Methods We have prospectively gathered data from 52 adult patients, which had recent or past history of MI. Exclusion criteria were the presence of atrial fibrillation, unknown coronary anatomy, significant valvular disease, left branch block, ventricular pacing and poor definition of endocardial borders. Estimation of EF by SBP, RT3P and 3DE was performed in all patients and gathered by two experienced operators. The two operators were blinded for the coronary angiography results before volume quantification. They were also blinded for their own measurements, as well as for the other operator's measurements. Spearman's correlation and linear regression were performed for correlation analysis. Bland-Altman plot was used for agreement assessment among the different methods. Interobserver agreement was assessed by Cohen's kappa. Results Patient characteristics are shown in table 1. EF calculation was feasible in all patients. There were excellent correlations between EF measured by SBP vs 3DE and RT3P vs 3DE (r=0.813 and r=0.9 respectively). Test of equality between two correlation coefficients confirmed that EF by RT3P method is significantly more correlated with the reference method, compared with EF by SBP (p=0.004). We have also performed a further analysis to study this results in special subsets. In anterior MI subset, EF by RT3P correlated by 0.909 with 3DE, versus 0.826 from EF by SBP (p=0.019). In inferior MI subset, EF by RT3P correlated by 0.779 with the reference method, versus 0.706 from EF by SBP (p=0.246). Fig 1 Correlation and Bland-Altman plot Conclusions Estimation of EF using SBP and RT3P methods by experienced operators strongly correlate with EF determined by 3DE. The RT3P method showed the strongest correlation between the two methods, which may point to its usefulness in the evaluation of EF in patients with anterior wall motion abnormalities after myocardial infarction.

scholarly journals P900 The Heart Model: Automated LVEF calculation in the real world

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
G Dhunnoo ◽  
A Mills ◽  
E F Lloyd ◽  
A Sabra ◽  
A Margulescu ◽  
...  
Keyword(s):  
Correlation Coefficients ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Heart Model ◽  
Altman Plot ◽  
Endocardial Border ◽  
Independent Observer ◽  
Ventricular Ejection Fraction ◽  
Bland Altman Plot ◽  
Chamber View

Abstract Background Heart Model (HM) is a proprietary, model-based algorithm for measurement of left ventricular ejection fraction (LVEF) in a 3D dataset acquired from an apical 4-chamber view by transthoracic echocardiography (TTE). There is evidence for superior reproducibility compared to 2D echo methods for LVEF measurement. Objective To assess the correlation of LVEF by HM with conventional, 2D LVEF methods. Methods All TTEs performed between 04-08/02/2019 by 2 HM-trained sonographers were included. Demographic characteristics, indication for TTE, LVEF by Simpson"s (LVEF_S), by "eyeballing" (LVEF_EB) and by HM (LVEF_HM), were recorded; LVEF for each study was also estimated by eye-balling by an experienced observer unaware of the reported LVEF (LVEF_IND). We compared LVEF by each method, their reciprocal correlations and their correlation with LVEF_HM. Image quality was rated excellent (endocardial border visible for all segments in the 3 apical views), good (&lt; 1 segment was not visible / view), adequate (&lt; 3 segments were not visible) and limited (&lt;4 segments were not visible). Indications for TTE were: assessment of LVEF in 1/3 of the studies, murmurs in 1/5, and other indications in the rest. Results We included 74 patients (42 M, mean age (SD) 69.8(13.9), range 18-92 years). Forty-nine (66%) patients were in sinus rhythm, 23 (31%) were in AF, and the rest were in various paced rhythms. Fifty patients (68%) had excellent, good or adequate images. The EFs calculated by different methods are shown in the Table (p &gt; 0.05 for all), an the Bland Altman plot (LVEF_EB vs HM) in the figure. LVEF_HM correlated modestly with the other methods if all studies were included (r = 0.535 LVEF_HM vs. LVEF_EB); the correlation improved if only good-quality studies were included (r = 0.769, p &lt; 0.001 for both). All combinations of LVEF_IND, LVEF_EB and LVEF_S had correlation coefficients &gt;0.93. Conclusions The Heart Model algorithm for LVEF measurement correlates well with traditional 2D methods in patients with good endocardial border definition, where its use can potentially improve reproducibility and reduce exam duration. LVEF by method (good-quality studies) N = 50 Simpson"s Eyeballing HeartModel Independent Mean(%) 48.6 48.9 50.9 48.8 SD(%) 17.8 16.6 14.9 15.7 Median(%) 54.5 52.5 53 50 Range(%) 16-74 17.5-72.5 19-88 15-75 SD - standard deviation Independent - LVEF estimate (eyeballing) by independent observer unaware of reported EFs. LVEF_EB was chosen as it was available inall the reports. Abstract P900 Figure. Bland Altman Plot (LVEF_EB vs LVEF_HM)

scholarly journals A new sensitive and robust next-generation sequencing platform for HIV-1 drug resistance mutations testing

2021 ◽  
Author(s):  
Bin Yu ◽  
Changzhong Jin ◽  
Zixuan Ma ◽  
Ziwei Cai ◽  
Tingsen Li ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Sanger Sequencing ◽  
Resistance Mutations ◽  
Altman Plot ◽  
Blood Samples ◽  
Bland Altman Plot ◽  
Drug Resistance Mutations ◽  
Minority Variants ◽  
Generation Sequencing ◽  
Hiv 1

Next-generation sequencing (NGS) is a trending new platform which allows cheap, quantitative, high-throughput, parallel sequencing for minority variants with frequencies less than 20% of the HIV-1 quasi-species. In clinical setting, these advantages are crucial for choosing antiretroviral drugs with low genetic barriers and will potentially benefit treatment outcomes. In this investigation, we implemented the Boxin HIV-1 NGS platform for genotyping the drug-resistance-associated variants in PR/RT regions. Plasmids with known mutations were used to analyze the accuracy, reproducibility, and reliability of the Boxin NGS assay. Variant frequencies reported by Boxin NGS and the theoretical value were highly concordant. The Bland-Altman plot and the coefficient of variation (7%) suggested that the method has excellent reproducibility and reliability. Sanger sequencing confirmed the existence of these known variants with frequencies equal or above 20%. 78 blood samples were obtained from AIDS patients and underwent PR/RT region genotyping by Sanger sequencing and Boxin NGS. 33 additional drug resistance mutations were identified by Boxin NGS, 23/33 mutations were minority variants with frequencies below 20%. 15 blood samples obtained from AIDS patients underwent PR/RT region genotyping by Sanger sequencing, Boxin NGS, and Vela NGS. The Bland-Altman plot suggested that the variant frequencies detected by Boxin and Vela were highly concordant. Moreover, Boxin NGS assay detected five more minority variants with frequencies ranged from 1% to 20%. In a series of samples collected from 2016 to 2017, Boxin NGS reported a M184V mutation with a frequency of 4.92%, 3 months earlier than this mutation was firstly detected by Vela NGS and Sanger sequencing. In conclusion, Boxin NGS had good accuracy, reproducibility, and reliability. Boxin NGS was highly concordant with Sanger sequencing and Vela NGS. In terms of genotyping HIV-1 variants in PR/RT regions, Boxin NGS was more cost-efficient and appeared to have increased sensitivity without compromising sequence accuracy.

scholarly journals Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ramona A. Silvestre ◽  
Alejandro Almería Lafuente ◽  
Lucía Jiménez-Mendiguchía ◽  
Ana García-Cano ◽  
Rubén Romero López ◽  
...  
Keyword(s):  
Constant Error ◽  
Kappa Coefficient ◽  
Graves Disease ◽  
Clinical Validation ◽  
Diagnostic Validity ◽  
Thyrotropin Receptor ◽  
Altman Plot ◽  
Bland Altman Plot ◽  
Thyrotropin Receptor Antibodies ◽  
Receptor Antibodies

Abstract Objectives Graves’ disease is secondary to the presence of anti-thyrotropin receptor antibodies (TRAb), which stimulate thyroid hormones. TRab determination is crucial for etiological diagnosis. The objectives of this study were (i) to compare two methods for determining TRab by chemoluminiscence vs. standard TRACE-immunofluorescence; (ii) to determine the diagnostic validity of the three methods. Methods A retrospective study in 194 patients with a TRAb determination request. TRAb were determined by immunofluorescence (Kryptor, ThermoFisher) and chemiluminescence (Immulite, Siemens and Maglumi, Snibe). Clinical validation: medical records were reviewed and categorized according to thyroid function. Statistical analysis: Differences in quantitative variables were assessed by intraclass correlation coefficient, Bland–Altman plot, and mean differences (mD). Qualitative variables were dichotomized by cut-off points; Kappa coefficient was calculated. Correlations were evaluated by Pearson’s coefficient and Passing-Bablok regression analysis. The diagnostic validity of the three methods was investigated. Results Kryptor-Immulite: mD: 1.2 (95%CI: −16 to >18). Passing-Bablok: Constant error (95%CI: −0.8349 to −0.5987). Proportional error (95%CI: 0.7862–1.0387). ICC: 0.86 (95%CI: 0.82–0.89). Kappa coefficient: 0.68 (95%CI 0.59–0.78). Kryptor-Maglumi: mD: −0.3 (95%CI: −12 to >12). Passing-Bablok: Constant error (95%CI: −0.7701 to >0.1621. Proportional error (95%CI: 0.8571 to 1.3179. ICC: 0.93 (95%CI: 0.89–0.97). Kappa coefficient: 0.53 (95%CI: 0.32–0.74). Diagnosis of Graves’ disease was confirmed in 113 patients (Kryptorf showed better specificity and positive predictive value, whereas Immulite demonstrated better sensitivity and negative predictive value). Conclusions The three methods have a good diagnostic performance for Graves’ disease, with superimposable results on Bland–Altman plot. Interchangeability was not confirmed on the regression and agreement analysis, with the presence of biases.

Investigating the Dutch Movement-Specific Reinvestment Scale in people with stroke

2012 ◽  
Vol 27 (2) ◽  
pp. 160-165 ◽  
Author(s):  
Melanie Kleynen ◽  
Susy M Braun ◽  
Anna JHM Beurskens ◽  
Jeanine A Verbunt ◽  
Rob A de Bie ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Limits Of Agreement ◽  
Rehabilitation Centre ◽  
Altman Plot ◽  
Rehabilitation Process ◽  
Bland Altman Plot ◽  
Intraclass Correlation Coefficients ◽  
Conscious Control

Objective: Reinvestment is a phenomenon in which conscious control of movements that are best controlled automatically disrupts performance. The propensity for reinvestment may therefore play an important role in the movement rehabilitation process. The Movement-Specific Reinvestment Scale measures an individual’s propensity for reinvestment. The aim of this study was to translate the scale for use with Dutch participants with stroke and to assess its reliability. Design: A test–retest design. Setting: In community after discharge from rehabilitation centre. Subjects: Forty-five people with stroke. Measures: Reliability of the translated scale was assessed using intraclass correlation coefficients (ICC) and Bland–Altman plot. Results: The ICC was 0.85 (95% confidence interval (CI) 0.74–0.91). Limits of agreement ranged from −2.38 to 3.10. Conclusion: The Dutch Movement-Specific Reinvestment Scale appears to be a reliable tool with which to assess the propensity for movement-specific reinvestment by people with stroke.

scholarly journals RELIABILITY OF ANTHROPOMETRIC MEASUREMENTS CONDUCTED IN NATIONAL PHYSICAL FITNESS STANDARD (SEGAK) ASSESSMENTS AMONG SCHOOL-AGED ADOLESCENTS IN TERENGGANU, MALAYSIA

2019 ◽  
Vol 19 (2) ◽  
pp. 141-148
Author(s):  
Nurzaime Zulaily ◽  
Aryati Ahmad ◽  
Mohd Razif Shahril ◽  
Fadzli Syed Abdullah ◽  
Amran Ahmed
Keyword(s):  
Physical Fitness ◽  
Weight Status ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Anthropometric Measurements ◽  
Kappa Statistics ◽  
Altman Plot ◽  
Cohen’S Kappa ◽  
Bland Altman Plot ◽  
Cohen's Kappa

School-based health programs implemented by the Malaysian Ministry of Education (MOE) through the National Physical Fitness Standard (SEGAK) assessments provided an important platform in health status monitoring among schoolchildren. However, to date, there is still no reliability study conducted on this method. Therefore, this study aimed to determine the reliability of the anthropometric data collected by physical education (PE) teachers in the SEGAK assessments. Anthropometry measurements of standard six school adolescents involved in the Health of Adolescents in Terengganu study were taken by trained researchers using a standardised protocol. The anthropometrics data were then compared with PE teachers’ measurements from the SEGAK assessments obtained from the specifically developed Health Monitoring System database. Reliability of the anthropometric measurements were analysed using Pearson’s correlation test, Intraclass Correlation Coefficients (ICC), Bland-Altman plot and Cohen’s Kappa statistics. Intraclass correlation coefficient between teacher-measured and researcher-measured values shows good correlation in weight (ICC = 0.93), height (ICC = 0.98) and BMI (ICC = 0.91). The Bland-Altman plot showed a relatively small difference in mean of weight, height, and BMI between teacher-measured and researcher-measured value. The mean difference between teacher-measured and researcher-measured value of weight, height, and BMI were 1.8kg, 0.1cm, and 0.8kg/m2 respectively. Overall, Cohen’s Kappa statistics showed substantial agreement (κ = 0.642) in BMI categorisation between the two measurements. Findings from reliability analysis conducted affirmed that anthropometrics assessments conducted by PE teachers in SEGAK assessments are reliable to be used for identification of body weight status among school children and adolescents particularly in Terengganu, Malaysia.

Validity and repeatability of goniometry in normal horses

2016 ◽  
Vol 29 (04) ◽  
pp. 314-319 ◽  
Author(s):  
Henry Adair ◽  
David Levine ◽  
Denis Marcellin-Little
Keyword(s):  
Range Of Motion ◽  
Correlation Coefficients ◽  
Mean Difference ◽  
Altman Plot ◽  
Intra Class Correlation ◽  
Bland Altman Plot ◽  
Radiographic Measurements ◽  
The Mean ◽  
Metatarsophalangeal Joints ◽  
Flexion And Extension

SummaryPurpose: To assess validity and inter- and intra-tester reliability of equine goniometry and to establish values for carpal, meta -carpophalangeal, tarsal, and metatarsophalangeal flexion and extension in horses.Subjects: Seventeen healthy equine subjects of varied breeds were used.Methods: Three investigators blindly and independently measured in triplicate the extension and flexion of carpal, metacarpo -phalangeal, tarsal, and metatarsophalangeal joints of 17 horses after sedation. Radiographs of these joints in flexion and extension were acquired while under sedation. Goniometric and radiographic measurements were compared statistically and were correlated. A Bland-Altman plot was constructed. Inter- and intra-tester repeatability of goniometry were evaluated by calculating intra-class correlation coefficients (ICC). Mean flexion and extension of carpal, metacarpo -phalangeal, tarsal, and metatarsophalangeal joints were calculated.Results: Goniometric and radiographic measurements did not differ statistically and were significantly correlated (correlation coefficients ranged from 0.59 - 0.89). The mean difference between goniometric and radiographic measurements was 0.4°. Triplicate measurements collected by the three raters did not differ significantly within raters (ICC ranging from 0.950 - 0.995) and between raters (ICC ranging from 0.942 - 0.989).Conclusion: Goniometry is a valid and repeatable tool for evaluation of the range of motion of carpal, metacarpophalangeal, tarsal, and metatarsophalangeal joints in standing, sedated healthy horses.

Diagnostic Performance of the BHBCheck β-Hydroxybutyrate Meter for Hyperketonemia in Indian Cows and Buffaloes

2021 ◽  
Author(s):  
Vishal Surendrakumar Suthar ◽  
Deepak B Patil
Keyword(s):  
Blood Plasma ◽  
Diagnostic Performance ◽  
Laboratory Method ◽  
Reference Laboratory ◽  
Excellent Correlation ◽  
Altman Plot ◽  
Blood Samples ◽  
Bland Altman Plot ◽  
Test Characteristics ◽  
Reference Serum

Abstract The objective of the study was to evaluate diagnostic performance of the electronic hand-held BHBCheck meter (PortaCheck, Inc, USA; BHM) to determine blood, plasma and serum β-hydroxybutyrate (BHB) against serum BHB determined using reference laboratory method of Randox D-3 Hydroxybutyrate Ranbut assay (RSM) in Indian cows and buffaloes. Blood samples were collected by puncturing coccygeal vessels for determining serum and plasma BHB using BHM and serum BHB using RSM from 217 cows (Gir breed; median 42 DIM and 3rd lactation) and 223 buffaloes (non-descript; median 39 DIM and 3rd lactation) from nearby herds. Cow-side blood BHB were determined with BHM. The Pearson’s correlation between blood (0.988; 0.987), plasma (0.985; 0.983) and serum (0.985; 0.983) BHB determined using the BHM and serum BHB determined with the RSM were significant. Bland-Altman plot demonstrated an excellent agreement between blood, plasma and serum BHB determined with BHM, against the serum BHB determined with RSM. For hyperketonemia with reference serum BHB cut-off values ≥ 1.2 and 1.4 mmol/L determined with RSM; recorded optimized BHB thresholds, sensitivity and specificity for blood (≥ 0.9 to 1.0 mmol/L; 91 to 95% and 88 to 98%) plasma (≥ 0.9 to 1.0 mmol/L; 91 and 100%) and serum (≥ 0.9 to 1.0 mmol/L; 92 to 100% and 85 to 94%) with BHM in cows and buffaloes. In conclusion, BHB determined with BHM demonstrated an excellent correlation, agreement and test characteristics with BHB determined with RSM, hence, can accurately determine blood, plasma and serum BHB in cows and buffaloes.

scholarly journals Comparison of capillary, venous and buffy coat blood samples in detecting Plasmodium species among malaria suspected patients attending at Hamusite health center. A cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Getu Abeje ◽  
Woyneshet Gelaye ◽  
Getaneh Alemu
Keyword(s):  
Health Center ◽  
Detection Rate ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Buffy Coat ◽  
Blood Film ◽  
Capillary Blood ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Samples

Abstract Background Both capillary and venous blood samples have been interchangeably used for the diagnosis of malaria in Ethiopia. However, Plasmodium parasites are thought to be more concentrated in capillary than in venous blood. Hence, selecting a sample source where parasites are more concentrated is indispensable approach in order to maximize the accuracy of blood film microscopy. Therefore, the present study aimed to compare the detection rate and the parasitemia level of Plasmodium species from conventional capillary and venous blood films, and buffy coat preparations. Methods A facility based cross-sectional study was conducted from Feburary to March 2020 among 210 febrile patients attending Hamusite health center, northwest Ethiopia. Capillary and venous blood samples were collected and buffy coat was prepared from each sample. Thin and thick blood films were prepared, stained, and examined microscopically following standard protocol. Data were analysed using Statistical Package for Social Sciences Software version 20 and Med-Calc software version 19.3. Results Capillary blood buffy coat (61/210, 29.0%) had significantly higher detection rate as compared to capillary (48/210, 22.9%) and venous (42/210, 20.0%) blood films (p < 0.001). However, no significant difference was observed between capillary and venous blood films (p = 0.070) in detecting Plasmodium species. The highest and the lowest mean asexual stage parasite counts were found in capillary blood buffy coat (4692.88) and venous blood (631.43) films, respectively showing significant variations (p < 0.001). Mean gametocyte count was also highest in capillary blood buffy coat (3958.44). As compared to capillary blood buffy coat, the sensitivity of venous blood buffy coat, capillary blood film and venous blood film were 73.8, 78.7, 68.9%, respectively. Conclusion Capillary blood buffy coat samples showed the highest sensitivity in detecting and quantitating malaria parasites that its use should be promoted in clinical settings. However, conventional capillary and venous blood films could be used interchangeably.

Effects of Different Methods Used to Take Blood Samples on Blood Glucose Measurements

2021 ◽  
pp. 105477382110247
Author(s):  
Eda Ergin ◽  
Ayten Zaybak
Keyword(s):  
Blood Glucose ◽  
Glucose Tolerance Test ◽  
Venous Blood ◽  
Tolerance Test ◽  
Capillary Blood ◽  
Oral Glucose ◽  
Blood Samples ◽  
Significant Difference ◽  
Measurement Results ◽  
Quasi Experimental

The purpose of this study is to compare whether or not there is a difference between venous and capillary blood samples in blood glucose measurements and investigate the effects of different aseptic methods used in skin cleaning before collecting blood samples on measurement results. This quasi-experimental study was conducted with 109 patients. The capillary first and second blood drop values taken from the patients after fasting and at 2 hours following 75 g oral glucose tolerance test (OGTT) and capillary and venous blood glucose values were compared. There was no significant difference between the median venous blood glucose value and the capillary second blood drop value taken after wiping the finger with alcohol. There was no significant difference between the first and second blood drop values of capillary blood glucose 2 hours after OGTT.

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