scholarly journals Racial Differences in the Association of Mediterranean Diet with Cognitive Decline (P14-002-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Puja Agarwal ◽  
Yamin Wang ◽  
Lisa Barnes ◽  
Thomas Holland ◽  
Denis Evans ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Racial Differences ◽  
Mediterranean Diet ◽  
Sex Education ◽  
Cognitive Assessments ◽  
Funding Sources ◽  
The Us ◽  
Education Participation ◽  
The Mediterranean ◽  
The Impact

Abstract Objectives The US older population is on the rise and projected to be 42% minority by 2050. Cognitive impairment is one of the major public health concerns of an aging population, and diet is one possible modifiable risk factor. However, we have limited knowledge of diet associations with cognition in minorities as most of the findings are either not reported by race or the data is not available for non-white populations. In a previous study, we found Mediterranean diet associated with slower cognitive decline in the biracial population of Chicago Health and Aging Project (CHAP). In this study, we examined this association in CHAP separately by race (Blacks and Whites). Methods Analyses included 4985 participants of the Chicago Health and Aging Project (63% African American, mean age = 75 ± 6.0 years, mean education = 12.6 ± 3.6 years) who completed a food frequency questionnaire and at least two cognitive assessments (a composite of 4 cognitive tests) over an average follow-up of 6.3 years. Computed scores of adherence to the Mediterranean diet were analyzed in tertiles of intake. We used mixed models adjusted for age, sex, education, participation in cognitive activities, physical activity, and total calories. Results Among Whites, both the middle (β = 0.014, P = 0.06) and highest tertiles of Mediterranean scores (β = 0.022, P = 0.003) were associated with slower cognitive decline compared to the lowest tertile of scores. Among Blacks, only the highest tertile of Mediterranean scores was associated with slower cognitive decline (T3 vs. T1: β = 0.014, P = 0.016; T2 vs. T1: β = −0.004, P = 0.92). The associations remained similar when further adjusted for cardiovascular conditions. Conclusions The Mediterranean diet associations with cognition may vary by race. Further study is required to understand these potential racial differences for the impact of diet on cognition. Funding Sources RFAG054057.

scholarly journals Sex-Related Differences in the Effects of the Mediterranean Diet on Glucose and Insulin Homeostasis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Alexandra Bédard ◽  
Louise Corneau ◽  
Benoît Lamarche ◽  
Sylvie Dodin ◽  
Simone Lemieux
Keyword(s):  
Sex Differences ◽  
Insulin Sensitivity ◽  
Mediterranean Diet ◽  
Sex Difference ◽  
Premenopausal Women ◽  
Nonesterified Fatty Acids ◽  
Time Interaction ◽  
Insulin Homeostasis ◽  
The Mediterranean ◽  
The Impact

Objective. To document sex differences in the impact of the Mediterranean diet (MedDiet) on glucose/insulin homeostasis and to verify whether these sex-related effects were associated with changes in nonesterified fatty acids (NEFA).Methods. All foods were provided to 38 men and 32 premenopausal women (24–53 y) during 4 weeks. Variables were measured during a 180 min OGTT before and after the MedDiet.Results. A sex-by-time interaction for plasma insulin iAUC was found (men: −17.8%,P=0.02; women: +9.4%,P=0.63;Pfor sex-by-time interaction = 0.005). A sex-by-time interaction was also observed for insulin sensitivity (Cederholm index,P=0.03), for which only men experienced improvements (men: +8.1%,P=0.047; women: −5.9%,P=0.94). No sex difference was observed for glucose and C-peptide responses. Trends toward a decrease in NEFA AUC (P=0.06) and an increase in NEFA suppression rate (P=0.06) were noted, with no sex difference. Changes in NEFA were not associated with change in insulin sensitivity.Conclusions. Results suggest that the more favorable changes in glucose/insulin homeostasis observed in men compared to women in response to the MedDiet are not explained by sex differences in NEFA response. This clinical trial is registered with clinicaltrials.govNCT01293344.

scholarly journals Self-Perceived Physical Activity and Adherence to the Mediterranean Diet in Healthy Adolescents during COVID-19: Findings from the DIMENU Pilot Study

Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 622
Author(s):  
Angelo Galluccio ◽  
Giovanna Caparello ◽  
Ennio Avolio ◽  
Emanuele Manes ◽  
Simona Ferraro ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mediterranean Diet ◽  
Eating Habits ◽  
Wellness Programs ◽  
Health Impact ◽  
The Self ◽  
Global Pandemic ◽  
Mediterranean Diet Adherence ◽  
The Mediterranean ◽  
The Impact

The global pandemic coronavirus disease (COVID-19) resulted in restrictions which forced adolescents to stay at home and influenced their food habits and lifestyles with potential negative health impact. This study aims to investigate the self-reported physical activity (PA) and eating habits related to the consumption of Mediterranean foods in a sample of adolescents during the COVID-19 lockdown enrolled into the DIMENU study. A web survey was launched for 91 adolescents (aged 15–17 years) to assess their adherence to the Mediterranean Diet using the KIDMED test and lifestyle habits using a questionnaire designed following recommendations by Italian National Institute of Health (ISS score). Our results indicate that most of the sample declared no changes in eating habits and PA without sex differences. After dividing the sample into active and sedentary groups based on the self-perceived PA, we found that KIDMED and ISS scores were significantly higher (p = 0.0028 and p = 0.0001, respectively) in active adolescents. Moreover, KIDMED was positively correlated with ISS only in active adolescents (r = 0.311, p = 0.0185). In conclusion, our data underline the impact of the PA on the Mediterranean diet adherence in adolescents during the lockdown, suggesting the usefulness of promoting wellness programs directed towards inactive individuals to increase their awareness on the importance of healthy lifestyles.

Does adherence to the Mediterranean diet modify the impact of smoking on health?

Public Health ◽  
2009 ◽  
Vol 123 (6) ◽  
pp. 459-460 ◽  
Author(s):  
C.I. Vardavas ◽  
A. Papadaki ◽  
W.H.M. Saris ◽  
A.G. Kafatos
Keyword(s):  
Mediterranean Diet ◽  
The Mediterranean ◽  
The Impact

The role of Mediterranean diet in the course of subjective cognitive decline in the elderly population of Greece: results from a prospective cohort study

2021 ◽  
pp. 1-29
Author(s):  
George S. Vlachos ◽  
Mary Yannakoulia ◽  
Costas A. Anastasiou ◽  
Mary H. Kosmidis ◽  
Efthimios Dardiotis ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Mediterranean Diet ◽  
The Elderly ◽  
Protective Role ◽  
Subjective Cognitive Decline ◽  
Preventive Strategy ◽  
Food Groups ◽  
Medical Disorders ◽  
The Mediterranean

Abstract Very few data are available regarding the association of adherence to the Mediterranean Diet (MeDi) with Subjective Cognitive Decline (SCD) evolution over time. A cohort of 939 cognitively normal individuals reporting self-experienced, persistent cognitive decline not attributed to neurological, psychiatric or medical disorders from the Hellenic Epidemiological Longitudinal Investigation of Aging and Diet (HELIAD study) was followed-up for a mean period of 3.10 years. We defined our SCD score as the number of reported SCD domains (memory, language, visuoperceptual and executive), ranging from 0 to 4. Dietary intake at baseline was assessed through a food frequency questionnaire; adherence to the MeDi pattern was evaluated through the Mediterranean Diet Score (MDS) that ranged from 0 to 55, with higher values indicating greater adherence to the MeDi. The mean SCD score in our cohort increased by 0.20 cognitive domains during follow-up. After adjustment for multiple potential confounders, we showed that an MDS higher by 10 points was associated with a 7% reduction in the progression of SCD within one year. In terms of food groups, every additional vegetable serving consumption per day was associated with a 2.3% reduction in SCD progression per year. Our results provide support to the notion that MeDi may have a protective role against the whole continuum of cognitive decline, starting at the first subjective complaints. This finding may strengthen the role of the MeDi as a population-wide, cost-effective preventive strategy targeting the modifiable risk factors for cognitive decline.

Abstract 13: Adherence to Various Dietary Patterns and Risk of Recurrent Coronary Heart Disease and Mortality in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study

Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
James M Shikany ◽  
Monika M Safford ◽  
Joanna Bryan ◽  
PK Newby ◽  
Joshua S Richman ◽  
...  
Keyword(s):  
Racial Differences ◽  
Mediterranean Diet ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Lower Risk ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Mediterranean Diet Score ◽  
The Mediterranean ◽  
Diet Score

Background: We have shown that the Southern dietary pattern, characterized by added fats, fried foods, organ and processed meats, and sugar-sweetened beverages, is associated with a greater risk of incident CHD in REGARDS, a national, population-based, longitudinal cohort. We sought to determine if the Southern pattern, other dietary patterns, and the Mediterranean diet score were associated with CHD events and mortality in REGARDS participants who previously reported CHD. Methods: REGARDS enrolled white and black adults aged ≥45 years between 2003-2007. Data were analyzed from 3,562 participants with CHD at baseline. Participants completed an FFQ at baseline, from which 5 dietary patterns were derived through factor analysis (Table). The Mediterranean diet score was calculated for each participant. Expert-adjudicated CHD events included myocardial infarction and CHD death. Cox proportional hazards regression was used to model the association of the dietary patterns and score with CHD events and death, adjusting for sociodemographics, lifestyle factors, energy intake, anthropometrics, and medical conditions. Results: Over 7 years of follow-up, there were 581 recurrent CHD events and 1,098 deaths. In fully-adjusted analyses, the highest quartile of adherence to the alcohol/salads pattern and highest group of the Mediterranean diet score were associated with lower risk of recurrent CHD compared to the lowest quartile/group (HR: 0.76; 95% CI: 0.59 – 0.98, HR: 0.78; 95% CI: 0.62 – 0.98, respectively). The highest quartile of adherence to the Southern pattern was associated with higher mortality (HR: 1.57; 95% CI: 1.28 – 1.91), while the highest group of the Mediterranean diet score was associated with lower mortality (HR: 0.80; 95% CI: 0.68 – 0.95). Conclusions: While the Southern dietary pattern was not related to risk of recurrent CHD, it was associated with higher mortality in REGARDS participants with existing CHD. Greater adherence to a Mediterranean diet was associated with lower risk of recurrent CHD and mortality.

scholarly journals Effects of Olive Oil on Blood Pressure: Epidemiological, Clinical, and Mechanistic Evidence

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1548 ◽  
Author(s):  
Marika Massaro ◽  
Egeria Scoditti ◽  
Maria Annunziata Carluccio ◽  
Nadia Calabriso ◽  
Giuseppe Santarpino ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Olive Oil ◽  
Mediterranean Diet ◽  
Lifestyle Changes ◽  
Antihypertensive Medications ◽  
Hypertensive Patients ◽  
High Oleic ◽  
The Mediterranean ◽  
The Impact

The increasing access to antihypertensive medications has improved longevity and quality of life in hypertensive patients. Nevertheless, hypertension still remains a major risk factor for stroke and myocardial infarction, suggesting the need to implement management of pre- and hypertensive patients. In addition to antihypertensive medications, lifestyle changes, including healthier dietary patterns, such as the Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean diet, have been shown to favorably affect blood pressure and are now recommended as integrative tools in hypertension management. An analysis of the effects of nutritional components of the Mediterranean diet(s) on blood pressure has therefore become mandatory. After a literature review of the impact of Mediterranean diet(s) on cardiovascular risk factors, we here analyze the effects of olive oil and its major components on blood pressure in healthy and cardiovascular disease individuals and examine underlying mechanisms of action. Both experimental and human studies agree in showing anti-hypertensive effects of olive oil. We conclude that due to its high oleic acid and antioxidant polyphenol content, the consumption of olive oil may be advised as the optimal fat choice in the management protocols for hypertension in both healthy and cardiovascular disease patients.

scholarly journals From the Table to the Tumor: The Role of Mediterranean and Western Dietary Patterns in Shifting Microbial-Mediated Signaling to Impact Breast Cancer Risk

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2565 ◽  
Author(s):  
Tiffany M. Newman ◽  
Mara Z. Vitolins ◽  
Katherine L. Cook
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Mediterranean Diet ◽  
Dietary Patterns ◽  
Gut Microbiome ◽  
Western Diet ◽  
Diet Pattern ◽  
The Mediterranean ◽  
The Impact

Diet is a modifiable component of lifestyle that could influence breast cancer development. The Mediterranean dietary pattern is considered one of the healthiest of all dietary patterns. Adherence to the Mediterranean diet protects against diabetes, cardiovascular disease, and cancer. Reported consumption of a Mediterranean diet pattern was associated with lower breast cancer risk for women with all subtypes of breast cancer, and a Western diet pattern was associated with greater risk. In this review, we contrast the available epidemiological breast cancer data, comparing the impact of consuming a Mediterranean diet to the Western diet. Furthermore, we will review the preclinical data highlighting the anticancer molecular mechanism of Mediterranean diet consumption in both cancer prevention and therapeutic outcomes. Diet composition is a major constituent shaping the gut microbiome. Distinct patterns of gut microbiota composition are associated with the habitual consumption of animal fats, high-fiber diets, and vegetable-based diets. We will review the impact of Mediterranean diet on the gut microbiome and inflammation. Outside of the gut, we recently demonstrated that Mediterranean diet consumption led to distinct microbiota shifts in the mammary gland tissue, suggesting possible anticancer effects by diet on breast-specific microbiome. Taken together, these data support the anti-breast-cancer impact of Mediterranean diet consumption.

scholarly journals Science and Healthy Meals in the World: Nutritional Epigenomics and Nutrigenetics of the Mediterranean Diet

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1748 ◽  
Author(s):  
Fabio Caradonna ◽  
Ornella Consiglio ◽  
Claudio Luparello ◽  
Carla Gentile
Keyword(s):  
Mediterranean Diet ◽  
Disease Risk ◽  
Cooking Methods ◽  
Intangible Cultural Heritage ◽  
Protective Effects ◽  
Positive Health ◽  
Food Components ◽  
The Mediterranean ◽  
The Impact ◽  
Scientific Topic

The Mediterranean Diet (MD), UNESCO Intangible Cultural Heritage of Humanity, has become a scientific topic of high interest due to its health benefits. The aim of this review is to pick up selected studies that report nutrigenomic or nutrigenetic data and recapitulate some of the biochemical/genomic/genetic aspects involved in the positive health effects of the MD. These include (i) the antioxidative potential of its constituents with protective effects against several diseases; (ii) the epigenetic and epigenomic effects exerted by food components, such as Indacaxanthin, Sulforaphane, and 3-Hydroxytyrosol among others, and their involvement in the modulation of miRNA expression; (iii) the existence of predisposing or protective human genotypes due to allelic diversities and the impact of the MD on disease risk. A part of the review is dedicated to the nutrigenomic effects of the main cooking methods used in the MD and also to a comparative analysis of the nutrigenomic properties of the MD and other diet regimens and non-MD-related aliments. Taking all the data into account, the traditional MD emerges as a diet with a high antioxidant and nutrigenomic modulation power, which is an example of the “Environment-Livings-Environment” relationship and an excellent patchwork of interconnected biological actions working toward human health.

scholarly journals The Mediterranean Diet in the Stroke Belt: A Cross-sectional Study on Adherence and Perceived Knowledge, Barriers, and Benefits (P18-066-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Michael Greene ◽  
Caroline Knight ◽  
Olivia Jackson ◽  
Imran Rahman ◽  
Donna Burnett ◽  
...  
Keyword(s):  
Mediterranean Diet ◽  
Linear Regression Analysis ◽  
Demographic Variables ◽  
Dietary Guidelines ◽  
Amazon Mechanical Turk ◽  
Funding Program ◽  
The Us ◽  
Knowledge Barriers ◽  
The Mediterranean ◽  
Stroke Belt

Abstract Objectives The Mediterranean diet (MD) is recommended by the current Dietary Guidelines for Americans, yet little is known about the diet in the US, particularly in areas of high chronic disease. Thus, we investigated MD adherence and perceived benefits and barriers to consumption of the MD in the US Stroke Belt. Methods A survey containing 44 validated MD knowledge, barriers, and benefits (KBB) questions, a validated 14-question MD adherence screener, 7 questions based on the Precaution Adoption Model (stages of change), and 7 demographic/anthropometric questions was distributed systematically to US residents using Amazon Mechanical Turk. Responses from the Stroke Belt (SB; n = 304), California (CA; n = 489), and all other US states (OtherUS; n = 439) were obtained. The CA group served as the reference group. A linear model was used to assess KBB question scores in the groups (Model 1), adjusted for sex and age (Model 2), and all other demographic variables (Model 3). Multivariable linear regression analysis was used to assess the differences in total MD adherence scores between the groups adjusted for all covariates. Simple logistic regression for having heard of the MD with demographic variables was examined. Statistical analyses were conducted in R v3.5.2. Results Barriers on MD knowledge, convenience, sensory factors, and health and familiarity with the MD diet were significantly greater in the SB group, but not the OtherUS group, in all models (P < 0.05). Weight loss was found to be a significantly greater benefit in the SB group in all models (P < 0.05). For each point increase in MD adherence, a reduction in 0.32 and 0.48 points (P < 0.05) was observed in the SB and otherUS groups, respectively. In the full cohort, the odds for participants having heard of the MD prior to taking the survey significantly increased 12.50 times (95%CI, 2.56–226) for 65–74 year olds. The odds were also significantly increased (OR 1.68; 95%CI, 1.13–2.47 and OR 2.47; 95%CI, 1.45–4.32) for those with Bachelor's and Master's or professional degrees, respectively, while no significant differences were found with sex or race. Conclusions Our results identify key barriers and benefits of the MD in the SB which can inform targeted MD intervention studies. Funding Sources USDA Hatch Funding Program (MWG) and Haggard Family Annual Award in Nutrition and Dietetics (OJ).

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