Effects of Eggs and Egg Components on Cognitive Performance, Glycemic Response, and Subjective Appetite in Children Aged 9–14 Years (P14-017-19)

Abstract Objectives Childhood is a critical time for regular intake of high-quality nutrients to aid developing brains. Dietary protein and fat independently and additively enhance cognitive performance in adults, however there are limited studies in children. The objective of this study was to determine the effects of whole eggs and its components (egg whites [protein-rich, fat-free] vs. egg yolks [containing protein and essential fatty acids]) on cognitive performance, glycemic response, and subjective appetite in children. Methods Using a randomized within-subject repeated-measures design, 19 children (age: 12.2 ± 0.4 years) completed five test conditions, at least seven days apart. Following the consumption of a standardized breakfast 3 h prior to arriving at the laboratory, children consumed one of the following treatments: whole eggs (147 kcal), egg yolks (112 kcal), egg whites (35 kcal), full fat yogurt (147 kcal), or continued to fast. Cognitive performance, blood glucose, and subjective appetite were assessed at baseline and 15, 30, 60, and 90-min post-treatment. A battery of cognitive performance tests assessed attention, learning and memory, executive functioning, and spatial working memory. Results Word recall (learning and memory) was higher after egg yolks (Δ = 1.7 ± 0.6 words; P = 0.03) compared with egg whites. Change from baseline cognitive processing test scores (attention) were significantly higher (P < 0.05) after egg yolks by 1.11, 1.25, and 1.21 trials compared with whole eggs, egg whites, and yogurt, respectively. Change from baseline subjective average appetite was lower after yogurt compared with snack skipping (Δ = 9.7 ± 2.9 mm; P = 0.01). Change from baseline blood glucose was lower after yogurt compared with egg yolks (P = 0.001) and egg whites (P = 0.01); and blood glucose was lower after whole eggs compared with egg yolks (P = 0.02). Conclusions Egg yolks resulted in higher short-term learning and memory scores compared with egg whites, and attention was higher after egg yolks compared with egg whites, whole eggs and yogurt. In conclusion, consumption of egg yolks may be beneficial for supporting cognitive performance in children. Funding Sources Egg Nutrition Center.

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The Acute Effects of Yoga on Executive Function

Journal of Physical Activity and Health ◽

10.1123/jpah.10.4.488 ◽

2013 ◽

Vol 10 (4) ◽

pp. 488-495 ◽

Cited By ~ 74

Author(s):

Neha Gothe ◽

Matthew B. Pontifex ◽

Charles Hillman ◽

Edward McAuley

Keyword(s):

Aerobic Exercise ◽

Cognitive Performance ◽

Repeated Measures ◽

Reaction Times ◽

Exercise Bout ◽

Exercise Session ◽

Acute Effects ◽

Cognitive Assessments ◽

Repeated Measures Design ◽

The Relationship

Background:Despite an increase in the prevalence of yoga exercise, research focusing on the relationship between yoga exercise and cognition is limited. The purpose of this study was to examine the effects of an acute yoga exercise session, relative to aerobic exercise, on cognitive performance.Methods:A repeated measures design was employed where 30 female college-aged participants (Mean age = 20.07, SD = 1.95) completed 3 counterbalanced testing sessions: a yoga exercise session, an aerobic exercise session, and a baseline assessment. The flanker and n-back tasks were used to measure cognitive performance.Results:Results showed that cognitive performance after the yoga exercise bout was significantly superior (ie, shorter reaction times, increased accuracy) as compared with the aerobic and baseline conditions for both inhibition and working memory tasks. The aerobic and baseline performance was not significantly different, contradicting some of the previous findings in the acute aerobic exercise and cognition literature.Conclusion:These findings are discussed relative to the need to explore the effects of other nontraditional modes of exercise such as yoga on cognition and the importance of time elapsed between the cessation of the exercise bout and the initiation of cognitive assessments in improving task performance.

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Effect of skipping breakfast for 6 days on energy metabolism and diurnal rhythm of blood glucose in young healthy Japanese males

American Journal of Clinical Nutrition ◽

10.1093/ajcn/nqy346 ◽

2019 ◽

Vol 110 (1) ◽

pp. 41-52 ◽

Cited By ~ 12

Author(s):

Hitomi Ogata ◽

Momoko Kayaba ◽

Yoshiaki Tanaka ◽

Katsuhiko Yajima ◽

Kaito Iwayama ◽

...

Keyword(s):

Blood Glucose ◽

Energy Metabolism ◽

Energy Expenditure ◽

Sedentary Behavior ◽

Repeated Measures ◽

Clinical Trial Registry ◽

Metabolic Chamber ◽

Repeated Measures Design ◽

Breakfast Skipping ◽

Skipping Breakfast

ABSTRACTBackgroundSkipping breakfast has become a common trend that may lead to obesity and type 2 diabetes. Previous studies, which imposed a single incidence of breakfast skipping, did not observe any decrease in 24-h energy expenditure. Furthermore, the effects of breakfast skipping on diurnal blood glucose profiles over 24 h are contradictory.ObjectiveThe aim of this study was to clarify the influence of 6 consecutive days of breakfast skipping and sedentary behavior on energy metabolism and glycemic control.MethodsTen young men participated in 2 trials (with or without breakfast) that lasted for 6 consecutive days, and the 2 trials were conducted 1 wk apart with a repeated-measures design. During the meal intervention, each subject's blood glucose was measured using the continuous glucose monitoring system. If breakfast was skipped, subjects ate large meals at lunch and dinner such that the 24-h energy intake was identical to that of the 3-meal condition. At 2200 on the fifth day, the subjects entered a room-sized respiratory chamber, where they remained for 33 h, and were instructed to carry out sedentary behavior.ResultsThe glucose levels were similar between the 2 meal conditions during the first 5 d of meal intervention, but the blood glucose at 2300 was higher in the breakfast-skipping condition than in the 3-meal condition. Breakfast skipping elevated postprandial glycemic response after lunch on the first day of meal intervention. On the sixth day, there were no significant differences in 24-h energy expenditure and substrate oxidation. When subjects remained in a metabolic chamber, the level of physical activity significantly decreased, glycemic stability slightly deteriorated, and mean blood glucose over 24 h was higher in the breakfast-skipping trial than in the 3-meal trial.ConclusionsSedentary lifestyle and repeated breakfast skipping caused abnormal glucose fluctuations, whereas 24-h energy metabolism remained unaffected. Clinical Trial Registry: This trial was registered at http://www.umin.ac.jp/english/ as UMIN000032346.

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O034 Rockabye sailor: investigating the impact of simulated motion on sleep and cognitive performance

SLEEP Advances ◽

10.1093/sleepadvances/zpab014.033 ◽

2021 ◽

Vol 2 (Supplement_1) ◽

pp. A15-A16

Author(s):

R Matthews ◽

F Fraysse ◽

N Daniell ◽

P Schumacher ◽

S Banks

Keyword(s):

Sleep Quality ◽

Cognitive Performance ◽

Repeated Measures ◽

Sleep Time ◽

Motion Platform ◽

Subjective Sleep Quality ◽

Psychomotor Vigilance Test ◽

Repeated Measures Design ◽

Foot Motion ◽

The Impact

Abstract Background Many naval vessels are designed with sleeping berths orientated in a fore/aft direction. Reorientating the berths changes the rocking from side-to-side to head-to-foot. It is unknown what effect rocking orientation may have on sleep. Aim This study aimed to investigate the impact of a simulated fore/aft orientation (side-to-side motion) with a simulated athwartships berth orientation (head-to-foot motion), on sleep quality and quantity, and cognitive performance. Method 21 participants (13M/8F; 24.0±4.8 years; BMI 21.1±2.5) slept in berths on a motion platform replicating vessel motion. In a repeated measures design, each participant slept under three conditions in randomised order: 1) no motion, 2) fore/aft orientation (side-to-side motion), and 3) athwartships orientation (head-to-foot motion). Measurements of sleep (ambulatory polysomnography), sleepiness (Karolinska Sleepiness Scale: KSS), and vigilance (Psychomotor Vigilance Test: PVT) were analysed using Mixed Effects ANOVA. Results Participants’ total sleep time was shorter (p<0.001), sleep efficiency was reduced (p<0.001), they woke more frequently (p<0.001), and their sleep contained less REM (p<0.001) in the athwartships orientation (head-to-foot motion) compared to the no motion, and fore/aft orientation (side-to-side motion) conditions. Participants’ also reported significantly higher sleepiness on KSS (p=0.006), poorer subjective sleep quality (p<0.001), and displayed worse vigilant attention on PVT (p=0.03) following the athwartships orientation compared to the two other conditions. Discussion The simulated athwartships bunk orientation (head-to-foot motion) negatively impacted sleep and cognitive performance. These results may have implications for crew wellbeing. The data also gives unique theoretical insight into the effects of different types of rhythmic movement on sleep. Funding DSTG

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Martial Art Training and Cognitive Performance in Middle-Aged Adults

Journal of Human Kinetics ◽

10.1515/hukin-2015-0083 ◽

2015 ◽

Vol 47 (1) ◽

pp. 277-283 ◽

Cited By ~ 5

Author(s):

Peter Douris ◽

Christopher Douris ◽

Nicole Balder ◽

Michael LaCasse ◽

Amir Rand ◽

...

Keyword(s):

Executive Function ◽

Cognitive Performance ◽

Processing Speed ◽

Repeated Measures ◽

Middle Aged ◽

Motor Tasks ◽

Repeated Measures Design ◽

Martial Art ◽

Treatment Conditions ◽

Middle Aged Adults

AbstractCognitive performance includes the processes of attention, memory, processing speed, and executive functioning, which typically declines with aging. Previous research has demonstrated that aerobic and resistance exercise improves cognitive performance immediately following exercise. However, there is limited research examining the effect that a cognitively complex exercise such as martial art training has on these cognitive processes. Our study compared the acute effects of 2 types of martial art training to aerobic exercise on cognitive performance in middle-aged adults. We utilized a repeated measures design with the order of the 3 exercise conditions randomly assigned and counterbalanced. Ten recreational middle-aged martial artists (mean age = 53.5 ± 8.6 years) participated in 3 treatment conditions: a typical martial art class, an atypical martial art class, and a one-hour walk at a self-selected speed. Cognitive performance was assessed by the Stroop Color and Word test. While all 3 exercise conditions improved attention and processing speed, only the 2 martial art conditions improved the highest order of cognitive performance, executive function. The effect of the 2 martial art conditions on executive function was not different. The improvement in executive function may be due to the increased cortical demand required by the more complex, coordinated motor tasks of martial art exercise compared to the more repetitive actions of walking.

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Role of Amino Acids in Blood Glucose Changes in Young Adults Consuming Cereal with Milks Varying in Casein and Whey Concentrations and Their Ratio

Journal of Nutrition ◽

10.1093/jn/nxaa275 ◽

2020 ◽

Vol 150 (12) ◽

pp. 3103-3113

Author(s):

Bonnie Kung ◽

Sylvie L Turgeon ◽

Shirley Vien ◽

Ruslan Kubant ◽

Dalia El Khoury ◽

...

Keyword(s):

Amino Acids ◽

Blood Glucose ◽

Repeated Measures ◽

Protein Concentration ◽

Postprandial Blood Glucose ◽

Total Protein Content ◽

Breakfast Cereal ◽

Repeated Measures Design ◽

Glucoregulatory Hormones

ABSTRACT Background Increasing the total protein content and reducing the casein to whey ratio in milks consumed with breakfast cereal reduce postprandial blood glucose (BG). Objectives We aimed to explore associations between plasma amino acids (AAs), BG, and glucoregulatory hormones. Methods In this repeated-measures design, 12 healthy adults consumed cereal (58 g) and milks (250 mL) with 3.1 wt% or high 9.3 wt% protein concentrations and with casein to whey ratios of either 80:20 or 40:60. Blood was collected at 0, 30, 60, 120, 140, 170, and 200 min for measurement of the primary outcome, BG, and for the exploratory outcomes such as plasma AA, gastric emptying, insulin (INS), and glucoregulatory hormones. Measures were made prior to and after an ad libitum lunch at 120 min. Exploratory correlations were conducted to determine associations between outcomes. Results Pre-lunch plasma AA groups [total (TAA), essential (EAA), BCAA, and nonessential (NEAA)] were higher after 9.3 wt% than 3.1 wt% milks by 12.7%, 21.4%, 20.9%, and 7.6%, respectively (P ≤ 0.05), while post-lunch AA groups were higher by 10.9%, 19.8%, 18.8%, and 6.0%, respectively (P ≤ 0.05). Except for NEAA, pre-lunch AAs were higher after 40:60 than 80:20 ratio milks by 4.5%, 8.3%, and 9.3% (P ≤ 0.05). When pooled by all treatments, pre-lunch AA groups associated negatively with BG (r/ρ ≥ −0.45, P ≤ 0.05), but post-lunch only TAA and NEAA correlated (r ≥ −0.37, P < 0.05). Pre-lunch BG was inversely associated with Leu, Ile, Lys, Met, Thr, Cys-Cys, Asn, and Gln (r/ρ ≥ −0.46, P ≤ 0.05), but post-lunch, only with Thr, Ala, and Gly (r ≥ −0.50, P ≤ 0.05). Pre-lunch associations between AA groups and INS were not found. Conclusions Protein concentration and the ratio of casein to whey in milks consumed at breakfast with cereal affect plasma AA concentrations and their associations with decreased BG. The decrease in BG could be explained by INS-independent mechanisms. This trial was registered at www.clinicaltrials.gov as NCT02471092.

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The Promise of Intergenerational Choir for Improving Psychosocial and Cognitive Health for those with Dementia: The Voices in Motion Project

The Arbutus Review ◽

10.18357/tar101201918962 ◽

2019 ◽

Vol 10 (1) ◽

pp. 66-82

Author(s):

Nicholas Tamburri ◽

Michaella Trites ◽

Debra Sheets ◽

Andre Smith ◽

Stuart MacDonald

Keyword(s):

High School Students ◽

Depressive Symptoms ◽

Cognitive Function ◽

Episodic Memory ◽

Repeated Measures ◽

Memory Function ◽

Medical Science ◽

Word Recall ◽

Repeated Measures Design

Rates of dementia continue to increase along with life expectancy. As neither dementia’s causenor its cure is well understood from the perspective of medical science, further investigations ofcomplementary lifestyle and non-pharmaceutical interventions are imperative. Although arts-basedtherapies have been explored selectively, the significance of these interventions for persons withdementia (PwD) remains undervalued in both the general population and scientific literature. Thisstudy aims to examine one promising lifestyle intervention, the effect of intergenerational choirparticipation, on psychosocial and cognitive function for PwD. Participants (n = 32), in partnershipwith their family caregivers and local high school students, participated in an intergenerational choirfor as many as three choir seasons spanning up to 18 months of follow-up. Participants underwent anexpansive assessment of psychosocial, physiological, and cognitive function every four to six weeksas part of an intensive repeated measures design. Here, the potential benefits of choir for PwD wereexplored in relation to change for select cognitive (Mini-Mental State Examination: MMSE; TrailMaking Task A: TMT-A; Word Recall) and psychosocial (Patient Health Questionnaire: PHQ-9)indicators. Multilevel modelling was used to index initial levels (at baseline) and change (spanningup to eight follow-up assessments) in function for measures of global cognition, executive functioning,episodic memory, and depressive symptoms. Notably, no significant declines were observed for MMSEor TMT-A tasks. As expected, episodic memory function continued to decline, with a significantlessening of depressive symptoms and signs observed for the PHQ-9. These results suggest thatdespite the progressive nature of underlying neuropathology for dementia subtypes like Alzheimer’sDisease, preservation of select cognitive functions as well as mitigation of psychosocial comorbidities(depressive symptoms) is possible through participation in an intergenerational choir.

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Glycemic response in nonracing sled dogs fed single starch ingredients and commercial extruded dog foods with different carbohydrate sources

Journal of Animal Science ◽

10.1093/jas/skaa241 ◽

2020 ◽

Vol 98 (8) ◽

Author(s):

Alexandra Rankovic ◽

Jennifer L Adolphe ◽

D Dan Ramdath ◽

Anna K Shoveller ◽

Adronie Verbrugghe

Keyword(s):

Blood Glucose ◽

Repeated Measures ◽

Interindividual Variation ◽

White Bread ◽

Glycemic Response ◽

Whole Grain ◽

White Rice ◽

Time To Peak ◽

Sled Dogs ◽

Green Lentils

Abstract This study adapted the established glycemic index (GI) methodology used in human research to perform two studies in sled dogs in order to assess the blood glucose-raising potential of pulse-based dog foods. The first was a pilot study (n = 6 dogs) to determine the GI of single starch sources (white bread, cooked white rice, and cooked green lentils) using a glucose solution as control. Next, the effect on glycemic and insulinemic meal responses and GI of commercial extruded dog foods containing different categories of starch sources (traditional grain, whole grain, grain-free, and vegan) were investigated on 11 dogs using a glucose control. Results were compared using repeated measures analysis of variance (ANOVA). Consumption of 10 g of available carbohydrate (Av CHO) was insufficient to elicit a measurable response in blood glucose for GI determination, and as such, the amount was increased to 25 g for the second study. The GI (±SE) of the single starch sources and dog foods was: white bread: 47 ± 11, cooked white rice: 71 ± 14, cooked green lentils: 60 ± 20 (P = 0.569), traditional grain: 83 ± 17, whole grain: 56 ± 8, grain-free: 41 ± 6, and vegan: 65 ± 15 (P = 0.154). No statistical differences in glycemic response over time were observed between the single starch sources or the extruded diets tested (P = 0.1412; P = 0.2651). The insulinemic response elicited by the extruded diets was also not different (P = 0.079); however, the traditional grain diet did have the slowest time to peak for insulin (P = 0.0078). Among single starch sources and extruded dog foods, there were no differences in the glycemic indices measured in this study. The GI methodology has not been validated for use in canine species, and it is likely that our results were due to higher interindividual variation or inadequate study power. Regardless, this study will serve to better define future studies to investigate the potential physiological benefits of low GI foods for dogs.

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Cognitive Performance Following Ingestion of Glucose–Fructose Sweeteners That Impart Different Postprandial Glycaemic Responses: A Randomised Control Trial

Nutrients ◽

10.3390/nu11112647 ◽

2019 ◽

Vol 11 (11) ◽

pp. 2647 ◽

Cited By ~ 3

Author(s):

Celeste Keesing ◽

Brianna Mills ◽

Charlene Rapsey ◽

Jillian Haszard ◽

Bernard Venn

Keyword(s):

Blood Glucose ◽

Cognitive Performance ◽

Glucose Concentration ◽

Declarative Memory ◽

Blood Glucose Concentration ◽

Word Recall ◽

Cognitive Test ◽

Randomised Control Trial ◽

Glycaemic Response ◽

The Mean

We aimed to investigate the isolated effect of glycaemia on cognitive test performance by using beverages sweetened with two different glucose–fructose disaccharides, sucrose and isomaltulose. In a randomised crossover design, 70 healthy adults received a low-glycaemic-index (GI) isomaltulose and sucralose beverage (GI 32) and a high-GI sucrose beverage (GI 65) on two occasions that were separated by two weeks. Following beverage ingestion, declarative memory and immediate word recall were examined at 30, 80 and 130 min. At 140 min, executive function was tested. To confirm that the glycaemic response of the test beverages matched published GI estimates, a subsample (n = 12) of the cognitive testing population (n = 70) underwent glycaemic response testing on different test days. A significantly lower value of mean (95% CI) blood glucose concentration incremental area under the curve (iAUC) was found for isomaltulose, in comparison to the blood glucose concentration iAUC value for sucrose, the difference corresponding to −44 mmol/L∙min (−70, −18), p = 0.003. The mean (95% CI) difference in numbers of correct answers or words recalled between beverages at 30, 80 and 130 min were 0.1 (−0.2, 0.5), −0.3 (−0.8, 0.2) and 0.0 (−0.5, 0.5) for declarative memory, and −0.5 (−1.4, 0.3), 0.4 (−0.4, 1.3) and −0.4 (−1.1, 0.4) for immediate free word recall. At 140 min, the mean difference in the trail-making test between beverages was −0.3 sec (−6.9, 6.3). None of these differences were statistically or clinically significant. In summary, cognitive performance was unaffected by different glycaemic responses to beverages during the postprandial period of 140 min.

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Effect of Chia (Salvia hispanica L.) Flour on Glycemic Response and Energy Intake in Healthy Adults (P06-099-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz031.p06-099-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Olivia Coelho ◽

Daniela Rocha ◽

Barbara Pereira da Silva ◽

Alessandra Silva ◽

Ana Paula Caldas ◽

...

Keyword(s):

Blood Glucose ◽

Food Intake ◽

Dietary Intake ◽

Energy Intake ◽

Repeated Measures ◽

Normal Weight ◽

Healthy Adults ◽

Glycemic Response ◽

Repeated Measures Anova ◽

Anova Test

Abstract Objectives Postprandial glycemic control is essential in both healthy and diabetic people, as hyperglycemia predisposes to complications associated with diabetes. The consumption of fiber-rich meals help to prevent and control undesirable glycemic changes. This study aimed to evaluate the effect of one-day consumption of chia on glycemic response and energy intake in healthy adults. Methods Single-blind, randomized, crossover design study involving healthy adults, normal weight (BMI 18.5–24.9 kg/m2), euglycemic (100 mg/dL), with no diabetes family history. They attended to the laboratory after 10–12 h fasting and received either 350 ml of a shake containing 10 g of chia flour (4.44 g of fiber) or 350 ml of a control shake (1.1 g of fiber)- similar in calories and macronutrients, containing 51 g of available carbohydrate - on two non-consecutive days (washout period). At each testing day, 60 minutes after shake intake a glucose solution (25 g) was provided. Capillary blood glucose was measured in fasting state (−60 min), immediately before (0 min), and 15, 30, 45, 60, 90, 120 minutes after glucose load. In addition, food intake was assessed 24-hour dietary recall was performed after each testing day. Habitual dietary intake was estimated using the semi-quantitative QFCA. The study was approved by the Local Ethics Committee. Repeated-measures ANOVA test was used to compare habitual dietary intake and consumption after shake. Two-way repeated measures ANOVA test followed by Bonferroni's post-hoc was used to assess the differences in postprandial blood glucose. Incremental area under the curve (AUC) of postprandial glycemia was calculated using the trapezoidal rule and paired sample t-test was used to compare them. All analyses were conducted using SPSS software. Statistical significance was set as p < 0.05. Results Fifteen subjects completed the study (14 female and 1 male). Consumption of chia (10 g of chia flour) did not change the blood glucose (p > 0.05) nor food intake (p > 0.05) among adults (25 ± 1 years), euglycemic (87.88 ± 1.21 mg/dL), normal weight (21.06 ± 0.28 kg/m2 and 23.23 ± 1.19% body fat percentual). Conclusions The one-day consumption of chia flour did not affect the glycemic response and did not interfere in energy intake in healthy individuals. The long-term effect of chia should be assessed. Funding Sources CNPq, CAPES, FAPEMIG, FUNARBE, DNS-UFV. Supporting Tables, Images and/or Graphs

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Power of Modified Brown-Forsythe and Mixed-Model Approaches in Split-Plot Designs

Methodology ◽

10.1027/1614-2241/a000124 ◽

2017 ◽

Vol 13 (1) ◽

pp. 9-22 ◽

Cited By ~ 1

Author(s):

Pablo Livacic-Rojas ◽

Guillermo Vallejo ◽

Paula Fernández ◽

Ellián Tuero-Herrero

Keyword(s):

Repeated Measures ◽

Statistical Power ◽

Mixed Model ◽

Covariance Structure ◽

Simulation Method ◽

Future Research ◽

Repeated Measures Design ◽

Fixed And Random Effects ◽

Split Plot ◽

High Level

Abstract. Low precision of the inferences of data analyzed with univariate or multivariate models of the Analysis of Variance (ANOVA) in repeated-measures design is associated to the absence of normality distribution of data, nonspherical covariance structures and free variation of the variance and covariance, the lack of knowledge of the error structure underlying the data, and the wrong choice of covariance structure from different selectors. In this study, levels of statistical power presented the Modified Brown Forsythe (MBF) and two procedures with the Mixed-Model Approaches (the Akaike’s Criterion, the Correctly Identified Model [CIM]) are compared. The data were analyzed using Monte Carlo simulation method with the statistical package SAS 9.2, a split-plot design, and considering six manipulated variables. The results show that the procedures exhibit high statistical power levels for within and interactional effects, and moderate and low levels for the between-groups effects under the different conditions analyzed. For the latter, only the Modified Brown Forsythe shows high level of power mainly for groups with 30 cases and Unstructured (UN) and Autoregressive Heterogeneity (ARH) matrices. For this reason, we recommend using this procedure since it exhibits higher levels of power for all effects and does not require a matrix type that underlies the structure of the data. Future research needs to be done in order to compare the power with corrected selectors using single-level and multilevel designs for fixed and random effects.

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