Influence of Myocardial Infarction on Serum Manganese, Copper, and Zinc Concentrations

1975 ◽  
Vol 21 (4) ◽  
pp. 578-581 ◽  
Author(s):  
Jacques Versieck ◽  
Fabrice Barbler ◽  
Albert Speecke ◽  
Julien Hoste
Keyword(s):  
Myocardial Infarction ◽  
Trace Elements ◽  
Neutron Activation Analysis ◽  
Serum Zinc ◽  
Serum Copper ◽  
Aminotransferase Activity ◽  
Copper And Zinc ◽  
Serum Aspartate Aminotransferase ◽  
Zinc Concentrations ◽  
Manganese Concentrations

Abstract Reportedly, serum manganese concentrations increase after myocardial infarction, closely correlated with increased serum aspartate aminotransferase activity. However, these conclusions are apparently based on analyses of contaminated samples. Serum manganese concentrations after myocardial infarction have been re-investigated by neutron activation analysis, and no significant increase could be demonstrated. Because serum copper and zinc could be determined simultaneously, analyses for these trace elements are also reported, which confirm the findings of others. After myocardial Infarction a statistically significant (0.02 < P < 0.05) increase in serum copper and a statistically significant (0.001 < P < 0.01) decrease in serum zinc were observed.

Changes in Serum Trace Elements after Surgery: Value of Copper and Zinc in Predicting Post-Operative Fatigue

1992 ◽  
Vol 20 (1) ◽  
pp. 12-19 ◽  
Author(s):  
A Cordova Martinez ◽  
J F Escanero Marcen
Keyword(s):  
Trace Elements ◽  
Total Protein ◽  
Serum Zinc ◽  
Serum Copper ◽  
Serum Total Protein ◽  
Muscular Performance ◽  
Skin Fold ◽  
Triceps Skin Fold ◽  
Zinc Concentrations ◽  
Serum Trace Elements

Triceps skin fold, arm muscular performance and fatigue were quantified, haematocrit measured and haemoglobin, serum total protein, albumin, transferrin, zinc and copper concentrations determined in 60 patients (36 women, 24 men) before and 3–45 days after surgery. On days 3 and 9 after surgery, there was a significant ( P < 0.05) decrease in serum zinc concentrations but by 45 days concentrations had return to pre-operative values. In contrast, serum copper concentrations were significantly ( P < 0.05) elevated until day 45. Haematocrit and haemoglobin and albumin concentrations were decreased significantly ( P < 0.05) 3 and 9 days after surgery, whereas serum total protein concentrations remained significantly ( P < 0.05) lower for 45 days compared with concentrations prior to surgery.

Diurnal Variation of Serum Copper and Zinc in Epileptics Receiving Anti-Convulsants

1986 ◽  
Vol 5 (3) ◽  
pp. 195-200 ◽  
Author(s):  
A. Taylor ◽  
K. Ghose
Keyword(s):  
Diurnal Variation ◽  
Reference Range ◽  
Serum Zinc ◽  
Serum Copper ◽  
Copper Level ◽  
Copper And Zinc ◽  
Urinary Copper ◽  
Zinc Concentrations ◽  
Zinc Levels ◽  
Patients With Epilepsy

1 Serial measurements of copper and zinc concentrations in serum were made at 06.00, 14.00, 22.00 and again at 06.00 hours in 37 male patients with epilepsy, aged between 9 and 19 years. Anti-convulsant drugs were administered at 08.00 and 20.00 hours, and standard hospital meals were allowed at 07.30, 12.00, 16.00 and 19.00 hours. 2 Similar to our previous results, eight patients (21.6%) had serum copper levels greater than the reference range (11.0–20.5 μmol/l) and this hypercupraemia was associated with carbamazapine and/or phenytoin medication. 3 No diurnal variation in serum copper level was observed. Serum copper concentration had no correlation with either 24 h urinary copper excretion or serum anti-convulsant drug levels. 4 Serum zinc concentrations were within the reference range (10–16.5 μmol/l), confirming our previous report. No relation with anti-convulsant medication or serum copper levels was found. 5 Diurnal variations in serum zinc levels with peak and trough concentrations at 06.00 and 14.00 hours, respectively, were observed. 6 It is proposed that these variations in serum zinc concentrations are a normal physiological process and is unlikely to be related to anti-convulsant drugs or epilepsy.

scholarly journals Serum Copper and Serum Zinc in Preeclampsia: Cause or Effect?

2020 ◽  
pp. 52-57
Author(s):  
Anjum A. K. Sayyed ◽  
Alka N. Sontakke
Keyword(s):  
Trace Elements ◽  
Case Control Study ◽  
Serum Zinc ◽  
Serum Copper ◽  
Total Serum ◽  
Control Group ◽  
Multisystem Disorder ◽  
Mean Values ◽  
Copper And Zinc ◽  
Control Study

Background: Preeclampsia is multisystem disorder. Despite its prevalence and severity, the pathophysiology of this multisystem disorder is poorly understood. In concern regarding the increasing number of preeclamptic cases and lack of data about the levels of trace elements in preeclampsia, a case-control study was conducted with aim to determine the trace elements like serum total copper and serum total zinc in preeclampsia. Aims: To estimate alterations in serum copper and serum zinc in preeclampsia and to compare them with normal pregnant women. Study Design: This is a case control study, carried out in the Department of Biochemistry, MIMER Medical College, Talegaon Dabhade, Pune. Methods: The present study consisted of 120 study participants. These were divided into two groups. Group I - normal pregnant women as control (n=60) and Group II - preeclamptic group (n=60). The serum levels of copper and zinc were determined by inductively coupled plasma atomic emission spectrometry (ICP- AES) technique at IIT Mumbai. Results: Analysis revealed that mean values of total serum copper and total serum zinc were 196.20 ± 25.9 and 77.15 ± 14.5 (µg/dl) respectively in control group. In preeclamptic group, the mean values of copper and zinc were 213.13± 38.6 and 76.23 ± 13.13 (µg/dl) respectively. Copper was significantly increased in preeclamptic group, while non-significant reduction in levels of zinc levels was observed when compared to control group. Conclusion: In the present study, significantly high serum copper was observed in preeclamptic patients. Presence of high copper levels may be related factor in the etiopathogenesis of preeclampsia. Estimation of trace elements like copper and zinc may help clinicians in early diagnosis and minimizing or delaying complications of preeclampsia, hence preventing harm to both mother & fetus.

Estimation of Trace Elements in Gingival Crevicular Fluid and Serum-Comparative Study in Healthy and Periodontitis

2017 ◽  
Vol 9 (5) ◽  
Author(s):  
Bhagavathami Meenaksh ◽  
Chitraa R. Chandran ◽  
Aravindhan Thathchari Ranganathan ◽  
Kavindapadi Venkateswaran Rama ◽  
Valarmathy Srinivasan
Keyword(s):  
Trace Elements ◽  
Inductively Coupled Plasma ◽  
Gingival Crevicular Fluid ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Serum Copper ◽  
Cross Sectional ◽  
Inductively Coupled ◽  
Significant Difference ◽  
Copper Zinc

Background: This study aims to determine and compare the levels of trace elements copper, zinc, selenium and chromium in GCF and serum of patients with periodontitis and healthy individuals. Methods: This cross sectional study includes 24 study subjects recruited from the patients reporting to the Department of Periodontics , Tagore Dental College Chennai. All the selected patients were subjected to a clinical examination done by a single examiner. The estimation of trace elements Copper, Zinc, Selenium and Chromium in GCF and serum is performed using Perkin Elmer optima 5300 Inductively Coupled Plasma Emission Spectrometer (ICPOES). Results: GCF and serum copper levels showed no significant difference in both periodontitis and healthy groups . Selenium levels tend to be the same in both groups. Serum zinc levels are more in periodontitis patients than healthy subjects (p less than 0.01). GCF chromium levels are found to be more in patients with periodontitis than healthy. Conclusions : More research is therefore needed to monitor the role of these trace elements C with an increased sample size to ascertain whether they are associated with a reduced risk of periodontitis.

Maternal Serum Copper and Zinc Concentrations in Normal and Small-for-Date Pregnancies

1984 ◽  
Vol 18 (4) ◽  
pp. 212-216 ◽  
Author(s):  
P. Kiilholma ◽  
M. Grönroos ◽  
P. Liukko ◽  
P. Pakarinen ◽  
H. Hyörä ◽  
...  
Keyword(s):  
Serum Copper ◽  
Maternal Serum ◽  
Copper And Zinc ◽  
Zinc Concentrations

ESTIMATION OF SERUM COPPER AND ZINC IN ANAEMIC PATIENTS

2016 ◽  
Vol 9 (5) ◽  
pp. 162
Author(s):  
Aishwarya Swaminathan ◽  
Sohara Parveen ◽  
Vishnupriya V ◽  
Gayathri R
Keyword(s):  
Study Design ◽  
Clinical Laboratory ◽  
Serum Zinc ◽  
Serum Copper ◽  
Healthy Individuals ◽  
Adequate Amount ◽  
Rich Food ◽  
Copper And Zinc ◽  
Group 2 ◽  
Zinc Levels

ABSTRACTObjective: Estimation of serum zinc and copper levels in anemic patients.Methods: The study design included 30 subjects presenting to clinical laboratory, global hospitals. The subjects were divided into 2 groups. TheGroup 1 consists of 15 healthy individuals and Group 2 consists of 15 anemic patients.Results: The serum copper and zinc levels were evaluated in anemic patients. The serum copper and zinc were found to be significantly lower inanemic patients when compared with normal individuals.Conclusion: Thus, the study concludes that the serum zinc and copper in anemic patients is significantly less when compared to the control individuals.Hence, it is important to add adequate amount of zinc and copper rich food in their diet to control the prevalence of anemia.Keywords: Anemia, Zinc, Copper, Hemoglobin.

THE RELATIONSHIP BETWEEN ESTABILISHED CORONARY RISK FACTORS AND SERUM COPPER AND ZINC CONCENTRATIONS IN A LARG PERSIAN POPULATION SAMPLE

2008 ◽  
Vol 9 (1) ◽  
pp. 136-137
Author(s):  
M. Ghayour-Mobarhan ◽  
H. Esmaeili ◽  
M. Azimi-Nezhad ◽  
A. Shapouri-Moghaddam ◽  
S. Parizadeh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Population Sample ◽  
Serum Copper ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Copper And Zinc ◽  
Zinc Concentrations ◽  
The Relationship

Serum copper and zinc concentrations are lower in Iranian patients with angiographically defined coronary artery disease than in subjects with a normal angiogram

2007 ◽  
Vol 21 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Seyyed Mohammad Reza Kazemi-Bajestani ◽  
Majid Ghayour-Mobarhan ◽  
Mahmoud Ebrahimi ◽  
Mohsen Moohebati ◽  
Habib Allah Esmaeili ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Copper ◽  
Copper And Zinc ◽  
Zinc Concentrations ◽  
Artery Disease ◽  
Iranian Patients

scholarly journals TRACE METALS IN CANCER PATIENTS AND THEIR CORRELATION WITH RENAL FUNCTION

2003 ◽  
Vol 42 (146) ◽  
pp. 71-73
Author(s):  
Shankhar Majhi ◽  
B D Toora ◽  
S K Sen ◽  
K Anantha ◽  
N Anantha
Keyword(s):  
Trace Elements ◽  
Trace Metals ◽  
Cancer Patients ◽  
Serum Zinc ◽  
Serum Copper ◽  
The Body ◽  
Significant Elevation ◽  
Super Oxide Dismutase ◽  
Carcinoma Stomach ◽  
Cu And Zn

ABSTRACTTwo trace elements, copper (Cu) and zinc (Zn) in serum are elevated in cancer patients since both areconstituents of super oxide dismutase (SOD) as metalloenzyme, the enzyme that scavenge free radicals andactivated oxygen species in the body. The study of 52 cancer patients comprising of 31 carcinoma stomachand 21 breast cancer showed the elevation of both of these trace elements in serum when compared to 32healthy controls and effected the kidney functions as a consequences. Serum Cu and Zn were estimated byAtomic Absorption Spectrometer (AAS), analyzed statistically by student "t" test and marked elevationwas observed in cancer patient compared to healthy controls. Serum Cu and Zn values were 98.13 ± 17.49μg/dl 99..57 ± 13.91 μg /dl respectively in 38 healthy subjects and these trace metals were 156.23 ± 31.02 μg/dl and 171.86 ± 35.15 μg/dl in 52 cancer patients showing significant elevation (P <0.001). These elevatedelements were routed through kidneys and damaged nephrons since both of them are cationic heavy metals.Nephrotoxicity of these trace metals was reflected as elevated level of blood urea and creatinine and werefound to be 27.44 ± 7.72 mg /dl and 0.83 ± 0.30 mg/dl in control groups and 64.49 ± 49 mg /dl and 1.60 ± 0.72mg/dl in cancer patients respectively, a significant elevation (P<0.001) in study group. The elevation ofthese parameters may indicate renal origin.Key Words: Serum copper, serum zinc, super oxide dismutase, carcinoma stomach, carcinoma breastand nephrotoxicity.

Serum Zinc, Iron, and Copper Concentrations during Typhoid Fever in Man: Effect of Chloramphenicol Therapy

1975 ◽  
Vol 21 (4) ◽  
pp. 528-532 ◽  
Author(s):  
Robert S Pekarek ◽  
R M Kluge ◽  
H L DuPont ◽  
R W Wannemacher ◽  
R B Hornick ◽  
...  
Keyword(s):  
Typhoid Fever ◽  
Serum Iron ◽  
Iron Concentration ◽  
Serum Zinc ◽  
Salmonella Typhi ◽  
Serum Copper ◽  
Related Phenomenon ◽  
Iron And Zinc ◽  
Zinc Concentrations ◽  
Metal Monitoring

Abstract In volunteers experimentally infected with Salmonella typhi, serum iron and zinc concentrations became significantly depressed and there was a concomitant rise in serum copper before the onset of overt clinical illness. However, after several days of fever and the initiation of chloramphenicol therapy, serum iron and zinc concentrations significantly increased. Additional studies—in volunteers with typhoid fever treated with chloramphenicol, in a volunteer with typhoid fever receiving cefazolin and gentamicin, and in untreated rhesus monkeys infected with Salmonella typhimurium—provided evidence that the increase in serum iron concentration during the febrile phase was the result of chloramphenicol therapy, whereas the increase in serum zinc concentrations was a disease-related phenomenon. The importance of trace-metal monitoring during infectious disease and chemotherapy is discussed

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