Ratio of Serum Tartrate-Inhibitable Acid Phosphatase to Total Serum Protein in Benign Prostatic Hypertrophy and Prostatic Carcinoma

1992 ◽  
Vol 38 (2) ◽  
pp. 276-277 ◽  
Author(s):  
George Petrovich ◽  
Jasna Ursich-Jankovich ◽  
Zeijko Prijovich
Keyword(s):  
Acid Phosphatase ◽  
Serum Protein ◽  
Prostatic Carcinoma ◽  
Benign Prostatic Hypertrophy ◽  
Prostatic Hypertrophy ◽  
Total Serum Protein ◽  
Total Serum ◽  
Control Group ◽  
Activity Concentrations ◽  
Specific Activities

Abstract The activity concentration and the specific activity (the ratio of enzyme activity to total serum protein) of the tartrate-inhibitable fraction of acid phosphatase [orthophosphoric monoester phosphohydrolase (acid optimum), EC 3.1.3.2; TIAP] were related to benign prostatic hypertrophy and to prostatic carcinoma. As expected, the TIAP activity concentrations assayed in the sera of patients with benign prostatic hypertrophy were within the range of those assayed in normal human sera. In contrast, the specific activities of TIAP determined in the sera of patients with benign prostatic hypertrophy were significantly higher than those determined in the control group. In the sera of prostatic carcinoma patients, both the TIAP activity concentrations and the TIAP specific activities differed significantly (F = 730) from the normal values.

scholarly journals Effect of Quail Egg Administration on Some Liver Function Related Parameters

2017 ◽  
Vol 9 (2) ◽  
pp. 149-152
Author(s):  
Patrick E. ABA
Keyword(s):  
Serum Protein ◽  
Fasting Blood Glucose ◽  
Negative Control Group ◽  
Oral Route ◽  
Negative Control ◽  
Diabetic Rats ◽  
Total Serum Protein ◽  
Total Serum ◽  
Control Group ◽  
Group 5

There are a lot of testimonies on the therapeutic efficacies of quail egg on diabetics and on liver disorders. This study investigated synthetic and conjugatory states of the liver in diabetic rats administered varying concentrations of quail egg solution. Thirty (30) adult male albino Wistar rats were assigned to 5 groups of 6 rats each. Groups 2-5 of rats were injected with alloxan monohydrate intraperitoneally at the dose of 160 mg/kg, while rats in group 1 served as normal control. Upon establishment of fasting blood glucose level above 126 mg/dl, the rats in groups 2-4 were administered 30, 15 and 7.5 mg/ml of quail egg solution respectively for 7 days. Rats in groups 1 and 5 received distilled water (10 ml/kg) each. All treatments were through the oral route. At the end of the 7 days duration of the study, blood samples for serum protein and bilirubin assays were collected. Results indicated that the quail egg administration to alloxanized rats did not alter total serum protein and albumin values, but improved significantly (p<0.5) the conjugated bilirubin values compared to that of the negative control group (group 5). It was concluded that administration of quail egg solution to alloxanized rats aided hepatic conjugatory ability with little or no effect on its synthetic function.

The effect of different levels of crude protein on the pathophysiology of Haemonchus contortus infection in 2-year-old Boer dry does under confined conditions

2017 ◽  
Vol 57 (4) ◽  
pp. 719
Author(s):  
T. V. Can ◽  
M. A. Hohenhaus ◽  
P. J. Murray
Keyword(s):  
Serum Protein ◽  
Dietary Protein ◽  
Haemonchus Contortus ◽  
Haemoglobin Concentration ◽  
Basal Diet ◽  
Protein Supplementation ◽  
Total Serum Protein ◽  
Total Serum ◽  
Control Group ◽  
Cell Volumes

The effect of dietary protein supplementation on the pathophysiology of a single Haemonchus contortus infection in 2-year-old Boer dry does under confined conditions was examined. Twenty-four does were randomly confined in individual pens and allocated into three groups balanced by their liveweight. The goats in the Control group were offered a basal diet whereas goats in Treatments 1 and 2 were fed the basal diet plus 25% and 50% dietary protein increments, respectively. Each animal was orally administrated 100 H. contortus L3 larvae/kg liveweight on Day 0 of the experiment. The goat liveweights and FAMACHA scores were recorded at weekly intervals. Packed cell volumes, eosinophil percentage, haemoglobin concentration, total serum protein, globulin, and albumin concentrations were recorded on Days 0 and 14, and then at weekly intervals during the experiments. Faecal egg counts were measured on Days 0, 21, and then at weekly intervals thereafter. Antigen-specific IgA, IgG, and IgM titres were determined from Enzyme-linked immunosorbent assays tests on Days 0, 28, and at the termination of the experiment. The results of this study showed that a single H. contortus L3 infection did not cause pathogenic effects in 2-year-old Boer dry does. Dietary protein supplementation significantly lowered faecal egg count and significantly enhanced IgG titres (P < 0.05). However, the higher protein diets did not have any significant effects on liveweight, packed cell volumes, haemoglobin concentration, biological parameters (total serum protein, albumin, and globulin concentrations), and peripheral antibodies (IgA and IgM titres) between the treatments. Further investigations are required to clarify the role of protein supplementation to control H. contortus infection in goats.

scholarly journals The effect of using Ginger (Zingiber officinale) or parsley seeds (petroselinum sativum) on some of physiologically traits of black

2012 ◽  
Vol 36 (0A) ◽  
pp. 142-150
Author(s):  
Mohammed M. Dakheel
Keyword(s):  
Herbal Medicine ◽  
Blood Sugar ◽  
Serum Protein ◽  
Zingiber Officinale ◽  
Feed Additives ◽  
Physiological Traits ◽  
Total Serum Protein ◽  
Total Serum ◽  
Control Group ◽  
Globulin Level

The study was aimed to know the effect of adding 3% of grind zingiber officinale or 8% ofpetroselinum sativum seeds in the concentrate diet (400g/head/ daily) of the Black Iraqi Does (19does) in some physiological traits. Nineteen healthy weak-medium does were divided into threegroups, the first group of 6 does fed concentrate diet containing zingiber, while in the secondgroup (6) does were fed on a diet containing 8% grind petroselinum sativum seeds, however, theother does kept as control group and fed the concentrate diet free of the herbal medical additivesduring mid December 2009 up to end of May 2010. The results revealed that group, The first andsecond groups were highly significant (p>0.05) in their Hb and PCV during the late months ofthe study, also both feed additives caused significant (p>0.05) increase in WBCs, lymphocyte andmonocytes ratio, while they caused significant decrease in neutrophils compared with the controlgroup. The total serum protein and albumin of Animals of both groups fed herbal medicine werehighly significant (p>0.05) in comparing with the control group. While the globulin level was notaffected, also blood sugar of both groups fed zingiber or petroselinum seeds showed significant(p> 0.05) lower levels during the late months of the study.

scholarly journals Serum 4-Hydroxy-2-nonenal and Induced Nitric Oxide Synthase in Hypertension Patient

2017 ◽  
Vol 2 (1) ◽  
pp. 29-33
Author(s):  
Alaa H. Jawad ◽  
Ali Hammed ◽  
Hadeel Adil ◽  
Zyad Al-Qaisi ◽  
Amamer Redwan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Serum Protein ◽  
Inflammatory Diseases ◽  
Total Serum Protein ◽  
Total Serum ◽  
Control Group ◽  
Markers Of Oxidative Stress ◽  
Oxide Synthase

Hypertension (HT) And related diseases such as chronic kidney disease(CKD) share in that one of the main reasons for them is to increase the oxidative stress, which in turn increases the severity of the disease and exacerbation of symptoms. Reactive molecules produced from oxidative stress, in addition to causing tissue damage by oxidation of biomolecules like DNA, lipids, proteins and sugars; they are lead to the formation of mediators with potent inflammatory effect. The objective of this study was to investigate some markers of oxidative stress in hypertension (HT) and HT with CKD patients in addition to some biochemical parameters related to these diseases. This study involved 84 male subjects aged between (25-65) year equally divided into three groups, first and second one belong to HT and HT with CKD patients respectively from Al-yarmouk Teaching hospital, while the third one for apparently healthy 28 subjects considered as control group. For each subject in the three groups these markers and parameters were evaluated; 4-hydroxy-2-nonenl(4HNE), induced nitric oxide synthase(iNOS), albumin, urea, creatinine ,total serum protein. The results were compared to control; There was a significantly higher (p<0.01) in 4HNE, and iNOS levels in both HT and HT with CKD patients, while serum albumin and Total serum protein shows significantly (p<0.01) lower levels in both groups. The elevation levels of oxidative stress markers may be due to oxidative damage of tissues that caused by these inflammatory diseases. Was concluded that there was a positive relation between oxidation results from these diseases and their developments and suggest increase need to intake of antioxidants as precaution in front of these disease.

PARALLEL STUDIES OF COMPLEMENT AND COAGULATION IV. EFFECT OF CARBON TETRACHLORIDE

1951 ◽  
Vol 29 (2) ◽  
pp. 48-58
Author(s):  
Christine E. Rice ◽  
Paul Boulanger ◽  
P. J. G. Plummer
Keyword(s):  
Carbon Tetrachloride ◽  
Liver Injury ◽  
Serum Protein ◽  
Guinea Pigs ◽  
Fatty Degeneration ◽  
Blood Groups ◽  
Total Serum Protein ◽  
Total Serum ◽  
Coagulation Time ◽  
Complement Activity

To determine whether liver injury would result in a parallel decline in the complement titer and coagulative properties of the blood, groups of guinea pigs were given series of injections of the liver poison, carbon tetrachloride. Marked fatty degeneration of the liver, a decline in total serum protein and albumin, a decrease in complement activity, and a prolongation of coagulation time was observed in the treated animals. A general relationship was noted between the albumin-globulin ratio and the complement titer of the serum and between the complement titer and the coagulation time of the plasma.

Muscle Weight Relationship to Serum Proteins, Hemocytes, and Hepatopancreas in the Lobster, Homarus americanus

1967 ◽  
Vol 24 (11) ◽  
pp. 2339-2354 ◽  
Author(s):  
James E. Stewart ◽  
John W. Cornick ◽  
Diane M. Foley ◽  
M. F. Li ◽  
C. M. Bishop
Keyword(s):  
Serum Protein ◽  
Physiological Condition ◽  
Serum Proteins ◽  
Homarus Americanus ◽  
Total Serum Protein ◽  
Total Serum ◽  
Experimental Conditions ◽  
Muscle Weight ◽  
Beef Liver ◽  
The Relationship

Total serum protein values, hemocyte numbers, and muscle weights were determined for 216 intermolt lobsters immediately after their capture, and for 230 others held captive under a variety of dietary and environmental conditions. Average muscle values ranged from approximately 13% to the more normal 20–25% of the live animals' weight, depending upon experimental conditions. The total serum protein up to a level of 55 mg/ml was shown to be a reliable indicator of muscle weights, although the relationship was not identical for all lobster groups. It appeared to be modified chiefly by the areas from which the different groups were taken. Diet was more important than the temperatures (5 to 14 C) in affecting changes in muscle and serum protein values. Starvation caused a greater reduction (50 to 70%) in the size of the hepatopancreas than in the muscle. Histological examination of the hepatopancreatic tissue showed that the lipid content was markedly reduced upon starvation and that a degeneration of this organ was apparent for lobsters fed a beef liver and herring diet. Measurement of serum proteins would appear to be a useful technique in experiments on lobster nutrition and have value, within specified limits, for assessing the physiological condition of wild lobsters.

THE EFFECT OF REPEATED HEAT AND COLD EXPOSURE ON SERUM PROTEIN COMPOSITION IN MAN

1967 ◽  
Vol 45 (4) ◽  
pp. 571-575 ◽  
Author(s):  
W. F. Blatt ◽  
J. Kerkay
Keyword(s):  
Serum Protein ◽  
Cold Exposure ◽  
Total Protein ◽  
Protein Composition ◽  
Total Serum Protein ◽  
Total Serum ◽  
Heat Acclimatization ◽  
Albumin Content ◽  
Protein Serum ◽  
Lipoprotein Distribution

Total protein, serum protein, and lipoprotein electrophoretic distribution and hematocrit values were determined in two groups of men during acclimatization to 6 weeks of cold and 11 days of heat respectively. After 3 weeks of cold exposure total serum protein and albumin content decreased, while the globulin fractions increased; thus, the calculated albumin/globulin ratio was significantly depressed. During the last 2 weeks, these parameters gradually returned to control values. Overall, the protein changes during heat acclimatization were minimal, although the globulins decreased slightly, yielding a small increase in the albumin/globulin ratio. The hematocrit levels were significantly lowered during both environmental exposures, whereas the lipoprotein distribution remained essentially unchanged.

Determination of Total Serum Protein Levels Fed by Hot Smoked Rainbow Trout (Oncorhynchus mykiss) Diets in Rats

2008 ◽  
Vol 3 (4) ◽  
pp. 246-251
Author(s):  
Suleyman Kaleli ◽  
Mustafa Unlusayin ◽  
Sengul Bilgin ◽  
Levent Izci ◽  
Ali Gunlu
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Serum Protein ◽  
Total Serum Protein ◽  
Total Serum ◽  
Protein Levels ◽  
Rainbow Trout Oncorhynchus Mykiss

scholarly journals Serum proteinogram of the Campeiro horse

2019 ◽  
Vol 71 (2) ◽  
pp. 363-368
Author(s):  
A.F. Souza ◽  
J. Schade ◽  
A.F. Ramos ◽  
M.S.M. Albuquerque ◽  
G.V. Fonteque ◽  
...  
Keyword(s):  
Serum Protein ◽  
Serum Proteins ◽  
Reference Interval ◽  
Total Serum Protein ◽  
Total Serum ◽  
Serum Concentrations ◽  
Reproductive Condition ◽  
Serum Fractions ◽  
Pregnancy Status ◽  
Biuret Method

ABSTRACT The aim of this study to measure the fractions of the total serum proteins of the Campeiro horse and identify the influences of biological variants. Blood samples were taken in 138 horses of the breed Campeiro for measuring the concentration of total serum protein by the biuret method. Serum concentrations of protein fractions were measured by electrophoresis using agarose gel. Groups were formed according to age, sex and reproductive condition. The average values of serum fractions: albumin (2.85±0.36g/dl), alpha 1 (0.28±0.11g/dl), alpha 2 (0.26±0.08g/dL) beta 1 (0.57±0.15g/dl), beta 2 (0.89±0.28g/dL), gamaglobulinas (1.86±0.34g/dL), albumin/globulin ratio (0.75±0.18) and 2.5% percentile and 97.5% had slight differences in relation to the reference interval proposed for the species. They observed higher values of alpha 1 and 2 globulins in the group from that had six to eight years old and gammaglobulins in group above 13 years old. Serum protein concentrations were similar in horses and mares and between non-pregnant and pregnant. Sex and pregnancy status did not affect serum proteinogram. Alpha and gammaglobulins have higher values as the age increases. Serum proteinogram of Campeiro horses shows variations that have to be considered in the interpretation of laboratory tests.

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