scholarly journals P401 Sarcopenia in children and young adults with primary sclerosing cholangitis and IBD

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S371-S372
Author(s):  
E Shteyer ◽  
R Cytter-Kuint ◽  
L Winberg
Keyword(s):  
Young Adults ◽  
Nutritional Status ◽  
Sclerosing Cholangitis ◽  
Psoas Muscle ◽  
Control Group ◽  
Significant Difference ◽  
Apri Score ◽  
Inflammatory Bowel ◽  
Children And Young Adults ◽  
Magnetic Resonance Imaging Mri

Abstract Background Malnutrition is common in children with inflammatory bowel disease (IBD) and in liver diseases. The nutritional status can be assessed by evaluating for sarcopenia, which is described as the loss of muscle mass and/or strength that are reflected by decreased psoas muscle surface area (PMSA). Accumulating data shows association of PSMA with chronic diseases, however, literature regarding sarcopenia in children is still limited. The aim of this study is to assess sarcopenia in children and young adults with sclerosing cholangitis (PSC) with or without IBD. Methods Retrospective analysis of patients below 25 years of age diagnosed with PSC between the years 2010–2018 was done. Patients who performed magnetic resonance imaging (MRI) were included in the study. Detailed clinical, anthropometric, laboratory and imaging findings were recorded. The control group was comprised of children who underwent MRI due to suspected scoliosis or kidney structural anomalies and had normal study. PMSA was determined at intervertebral disc L3. Results Sixty-five patients were included in the study. Twenty with PSC with a mean age of 15.2 ± 5 years, 12 were female and 9 had IBD. The control group comprised of 45 healthy subjects with no significant difference in age, gender and BMI from the study group. There was no significant difference in PMSA between groups. However, PMSA significantly correlated with aspartate transaminase (AST) and Platelet Ratio Index (APRI) score (marker for hepatic fibrosis, r = −0.49, p = 0.02). Additionally, PMSA was significantly higher in patients who had both PSC and IBD (475.61 ± 136 vs. 789 ± 328, p = 0.01). Conclusion Children and young adults with concomitant PSC and IBD were in a better nutritional status in comparison to patients with PSC alone, as evidenced by a lesser degree of sarcopenia. Additionally, sarcopenia correlates to the degree of liver fibrosis assessed by APRI score. Further larger studies are warranted in order to corroborate the importance of sarcopenia in patients with PSC.

OBSERVATIONS OF TOTAL SERUM BASE IN CHILDREN AND YOUNG ADULTS BY A CONDUCTIVITY METHOD

PEDIATRICS ◽  
1949 ◽  
Vol 4 (6) ◽  
pp. 805-809
Author(s):  
W. M. KELSEY ◽  
L. B. LEINBACH
Keyword(s):  
Young Adults ◽  
Total Serum ◽  
Age Group ◽  
Conductivity Method ◽  
Normal Children ◽  
Significant Difference ◽  
Children And Young Adults ◽  
The Mean ◽  
Standard Deviations

Values for total serum base in 96 normal children under 12 years of age as determined by the conductivity method fell between 143 to 160.5 mEq./l. The mean was 153. Standard deviations for each age group are given. The values in 73 normal persons above the age of 12 varied from 142 to 160.5 mEq./l. The mean was 147 mEq./l. A statistically significant difference between the total serum base in children and adults was found.

Risk Factors for Venous Thromboembolism in Children and Young Adults With Inflammatory Bowel Disease

2019 ◽  
Vol 243 ◽  
pp. 173-179 ◽  
Author(s):  
Kerri McKie ◽  
Robert J. McLoughlin ◽  
Michael P. Hirsh ◽  
Muriel A. Cleary ◽  
Jeremy T. Aidlen
Keyword(s):  
Risk Factors ◽  
Inflammatory Bowel Disease ◽  
Young Adults ◽  
Venous Thromboembolism ◽  
Bowel Disease ◽  
Inflammatory Bowel ◽  
Children And Young Adults

scholarly journals P264 Analysis of nutritional status and nutrient intake in patients with inflammatory bowel disease: a prospective, case–control study

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S282-S282
Author(s):  
Y E YOON ◽  
H M Kim ◽  
J H Kim ◽  
Y H Youn ◽  
H J Park ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Nutritional Status ◽  
Energy Intake ◽  
Body Fat ◽  
Bowel Disease ◽  
Nutrient Intake ◽  
Asia Pacific ◽  
Control Group ◽  
Fat Percentage ◽  
Inflammatory Bowel

Abstract Background Anthropometric data and dietary intake pattern are poorly known in Asian inflammatory bowel disease (IBD) patients. The aim of this study was to investigate the nutritional status and nutrient intake of IBD patients compared with control population. Methods From February to June 2018, a total of 65 outpatients, including 33 ulcerative colitis (UC) and 32 Crohn’s disease (CD) were prospectively enrolled in Gangnam Severance Hospital. As a control group, age- and gender-matched 260 subjects were included among the Korean National Health and Nutrition Examination Survey (KNHANES) data. Anthropometry and body composition data were collected by bioelectrical impedance analysis(BIA); meanwhile, nutrient intake was measured based on diet diary. Results Based on Asia Pacific criteria, more than half of both UC and control group were obese or overweight, on the other hands, CD was relatively low, about 1/3. Compared with the UC group, body fat index including both fat mass index (FMI) and body fat percentage (BFP) were significantly lower in the CD group. Following nutrients intake including intake of energy, carbohydrate, niacin, sodium and potassium were significantly lower in UC than the control group. Meanwhile, intake of carbohydrate, thiamine, niacin, sodium, potassium and iron was significantly lower in CD than the control group. In addition, the ratio of energy intake through protein and fat was significantly higher in the IBD than the control group. Conclusion Similar to the control group, more than half of UC patients were overweight or obesity, meanwhile, the proportion of obese patients in CD was lower than in the control group. The ratio of energy intake through protein and fat was significantly higher in IBD than in the control group. Our results may have clinical implications for risk of IBD development in terms of dietary pattern and further direction of nutritional intervention.

Serum Leptin in Children and Young Adults with Inflammatory Bowel Disease

1998 ◽  
Vol 26 (5) ◽  
pp. 500-505 ◽  
Author(s):  
Alison G. Hoppin ◽  
Lee M. Kaplan ◽  
David Zurakowski ◽  
Alan M. Leichtner ◽  
Athos Bousvaros
Keyword(s):  
Inflammatory Bowel Disease ◽  
Young Adults ◽  
Bowel Disease ◽  
Serum Leptin ◽  
Inflammatory Bowel ◽  
Children And Young Adults

scholarly journals Adequacy of food consumption in elderly Alzheimer’s disease in a community of Southern Brazil: a Cross-sectional study

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 671
Author(s):  
Glaucia Renee Hilgemberg ◽  
Aline Jacoski de Oliveira Krüger da Silva ◽  
Bárbara Luisa Fermino ◽  
Camila Diedrich ◽  
Simone Carla Benincá ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Nutritional Status ◽  
Neuronal Loss ◽  
Great Difficulty ◽  
Amyloid Peptide ◽  
Control Group ◽  
Food Record ◽  
Cross Sectional ◽  
Significant Difference

Background: Alzheimer's disease (AD) is the most common cause of dementia, with a multifactorial etiology, in which the person has great difficulty identifying feelings of hunger, satiety, and feeding, which may affect their nutritional status. Pathologically, it is associated with neurodegeneration of synapses followed by neuronal loss, accompanied by glial proliferation surrounded by neurofibrillary tangles, beta-amyloid peptide (Aβ) deposition, inflammation and cerebrovascular injury hindering the ability to perform activities of daily living. This study aimed to analyze quantitatively the differences between an elderly group with AD and a control group, in terms of macro and micronutrient consumption evaluation. Methods: the study involved 69 participants who were assessed via collection of anthropometric measurements (weight, height and body mass index) with nutritional status being assessed by 24-hour food recall and three-day food record. Cognitive assessments were performed using the Mini-Mental State Examination (MMSE) and Clinical Dementia Ranting (CDR). Results: The intake of lipids in patients with severe dementia, was lower (p <0.05). The consumption of proteins showed a decrease with demential advance. For vitamins, there was a significant difference (p <0.05) in the amount of thiamine, niacin, vitamin D, E and K and calcium, chromium and iodine minerals, which were significantly reduced in AD patients (p <0.05). Conclusions: Decreases in macronutrient and micronutrient consumption may result in a consequent impairment of nutritional status, dementia progression, and decreased quality and life expectancy of elderly patients with AD.

scholarly journals A Pedometer-based Intervention with Daily Walking Steps and its Relationship with Nutritional Status among Overweight/Obese University Students in Kuala Terengganu

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Kok J.L ◽  
Asma’, A. ◽  
Khairil-Shazmin K ◽  
Hayati M.Y
Keyword(s):  
Physical Activity ◽  
Waist Circumference ◽  
Nutritional Status ◽  
University Students ◽  
Control Group ◽  
Case Group ◽  
Baseline Activity ◽  
Dietary Record ◽  
Significant Difference ◽  
Before And After

Introduction: The aim of this study was to determine the effects of pedometer-based intervention and the relationship between daily walking steps and nutritional status among overweight/obese university students in Kuala Terengganu. Materials and methods: The study was an 8-week intervention study that included 23 overweight/obese university students. After 7 days of baseline activity, anthropometric data such as weight, height and waist circumference and a one-day dietary record were taken. The participants were divided into a control and case group. The control group (n=15) was instructed to continue with their normal activities and habits throughout the 8 weeks. The case group (n=8) was instructed to walk based on the targeted number of steps. Data such as body weight, waist circumference and a one-day dietary record were taken after the intervention. Results: Both case and control group show significant differences in body mass index (BMI) with p=0.017 and p=0.047 respectively. However, there is a large and significant difference between walking steps and BMI before and after intervention for the case group. There were no differences in any other study parameters during the 8-week study. Conclusion: In conclusion, short-term intervention with a pedometer increased physical activity and positively affected the BMI of overweight/obese participants. The use of a pedometer was efficient in measuring daily physical activity (r= 0.756, p< 0.05).

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