scholarly journals CENTRAL EQUILIBRIA IN MULTILOCUS SYSTEMS. I. GENERALIZED NONEPISTATIC SELECTION REGIMES

Genetics ◽  
1979 ◽  
Vol 91 (4) ◽  
pp. 777-798
Author(s):  
Samuel Karlin ◽  
Uri Liberman

ABSTRACT The generalized nonepistatic selection regime encompasses combinations of multiplicative and neutral viability effects distributed across a set of loci. These subsume, in particular, mixtures of the classical modes of multiplicative and additive fitness evaluations for multilocus traits. Exact analytic conditions for existence and stability of a multilocus Hardy-Weinberg (H-W) polymorphic equilibrium cmfiguration are ascertained. It is established that the central H-W polymorphism is stable only if the component loci are "overdominant" and sufficient recombination is in force. The H-W central equilibrium is never stable for tight linkage whenever some multiplicative selection effects are contributed by at least two of the loci involved. In the case of additive selection expression and individual overdominant loci, the H-W polymorphism is stable independently of the level of recombination. In the context of "natural" recombination schemes, "more recombination" enhances the stability 3f the H-W polymorphic equilibrium.

Genetics ◽  
1979 ◽  
Vol 91 (4) ◽  
pp. 799-816
Author(s):  
Samuel Karlin ◽  
Uri Liberman

ABSTRACT This paper is a continuation of the paper "Central Equilibria in Multilocus Systems I," concentrating on existence and stability properties accruing to central H-W type equilibria in multilocus bisexual systems acted on by generalized nonepistatic selection forces coupled to recombination events. The stability conditions are discussed and interpreted in three perspectives, and the influence of sexual differences in linkage relationships together with sex-dependent selection is appraised. In this case we deduce that the stability conditions of the H-W polymorphism in the bisexual model coincide exactly with the conditions for the corresponding monoecious model, provided that the recombination distribution imposed is that of the arithmetic mean of the male and female recombination distributions. A second concern has the same recombination distribution for both sexes, but contrasting selection regimes between sexes. It is then established that, with respect to discerning the relevance of the H-W equilibrium, there is an equivalent monoecious selection regime which is an appropriate "weighted combination" of the male and female selection forms. Finally, in the case where the selection and recombination structures are both sex dependent, a hierarchy of comparisons is elaborated, seeking to unravel the nature of selection-recombination interaction for monoecious versus diocecious systems.


2018 ◽  
Vol 33 (36) ◽  
pp. 1850216 ◽  
Author(s):  
M. Sharif ◽  
Arfa Waseem

This paper investigates the existence and stability of Einstein universe in the context of f(R, T, Q) gravity, where Q = R[Formula: see text] T[Formula: see text]. Considering linear homogeneous perturbations around scale factor and energy density, we formulate static as well as perturbed field equations. We parametrize the stability regions corresponding to conserved as well as non-conserved energy–momentum tensor using linear equation of state parameter for particular models of this gravity. The graphical analysis concludes that for a suitable choice of parameters, stable regions of the Einstein universe are obtained which indicates that the big bang singularity can be avoided successfully by the emergent mechanism in non-minimal matter-curvature coupled gravity.


Author(s):  
Erika Camacho ◽  
Richard Rand ◽  
Howard Howland

In this work we study a system of two van der Pol oscillators, x and y, coupled via a “bath” z: x¨−ε(1−x2)x˙+x=k(z−x)y¨−ε(1−y2)y˙+y=k(z−y)z˙=k(x−z)+k(y−z) We investigate the existence and stability of the in-phase and out-of-phase modes for parameters ε > 0 and k > 0. To this end we use Floquet theory and numerical integration. Surprisingly, our results show that the out-of-phase mode exists and is stable for a wider range of parameters than is the in-phase mode. This behavior is compared to that of two directly coupled van der Pol oscillators, and it is shown that the effect of the bath is to reduce the stability of the in-phase mode. We also investigate the occurrence of other periodic motions by using bifurcation theory and the AUTO bifurcation and continuation software package. Our motivation for studying this system comes from the presence of circadian rhythms in the chemistry of the eyes. We present a simplified model of a circadian oscillator which shows that it can be modeled as a van der Pol oscillator. Although there is no direct connection between the two eyes, they can influence each other by affecting the concentration of melatonin in the bloodstream, which is represented by the bath in our model.


Genetics ◽  
1982 ◽  
Vol 100 (1) ◽  
pp. 137-147
Author(s):  
S Karlin ◽  
J Raper

ABSTRACT Several multilocus models that incorporate both preferential mating and viability selection are studied. Specifically, a class of symmetric heterozygosity models are considered that assign individuals to phenotypic classes according to which loci are in heterozygous state regardless of the actual allelic content. Otherwise, an arbitrary number of loci, number of alleles per locus, and arbitrary recombination scheme, viability parameters and preferential mating pattern based on phenotypes are allowed. The conditions for the stability of a central polymorphism are indicated and interpreted. The effects of viability and preference selection may be summarized in a single quantity for each phenotypic class, a generalized fitness. Preferential assortative mating alone can produce stability for a central polymorphism as in the case of viability selection when sexual attractiveness or general fitness increases with higher levels of heterozygosity. The situation is more complex with sexual selection.


2013 ◽  
Vol 444-445 ◽  
pp. 796-800
Author(s):  
Yi Xiang Geng ◽  
Han Ze Liu

The existence and stability of subharmonic oscillations in a two end-fixed fluid conveying pipe whose base is subjected to a harmonic excitation are investigated. A Galerkin approach is utilized to reduce the equation of motion to a second order nonlinear differential equation. The conditions for the existence of subharmonic oscillations are given by using Melnikov method. The stability of subharmonic oscillations is discussed in detail by using action-angle variable and averaging method. It is shown that the velocity of fluid plays an important role in the stability of subharmonic oscillations.


2001 ◽  
Vol 15 (02) ◽  
pp. 167-176
Author(s):  
TAE-HOON CHUNG ◽  
SEUNGWHAN KIM

We investigate the effect of time delay on spatiotemporal dynamics in one-dimensional discrete excitable media with local delayed-interactions using coupled sine circle-maps. With the help of the stability analysis and numerical calculation of the pattern complexity entropy, we construct the phase diagram in the parameter space time delay and the nonlinear coupling. We find that the time delay affects the existence and stability of various regular states including homogeneously phase-locked and checkerboard states. In particular, the time delay induces the breakup of the homogeneously phase-locked state into spatiotemporal intermittency and the occurrence of multi-stability that depends on the winding number.


2009 ◽  
Vol 16 (5) ◽  
pp. 505-515 ◽  
Author(s):  
Chunyu Zhao ◽  
Hongtao Zhu ◽  
Ruizi Wang ◽  
Bangchun Wen

In this paper an analytical approach is proposed to study the feature of frequency capture of two non-identical coupled exciters in a non-resonant vibrating system. The electromagnetic torque of an induction motor in the quasi-steady-state operation is derived. With the introduction of two perturbation small parameters to average angular velocity of two exciters and their phase difference, we deduce the Equation of Frequency Capture by averaging two motion equations of two exciters over their average period. It converts the synchronization problem of two exciters into that of existence and stability of zero solution for the Equation of Frequency Capture. The conditions of implementing frequency capture and that of stabilizing synchronous operation of two motors have been derived. The concept of torque of frequency capture is proposed to physically explain the peculiarity of self-synchronization of the two exciters. An interesting conclusion is reached that the moments of inertia of the two exciters in the Equation of Frequency Capture reduce and there is a coupling moment of inertia between the two exciters. The reduction of moments of inertia and the coupling moment of inertia have an effect on the stability of synchronous operation.


2013 ◽  
Vol 13 (2) ◽  
Author(s):  
Laurent Véron

AbstractWe study existence and stability for solutions of −Lu + g(x, u) = ω where L is a second order elliptic operator, g a Caratheodory function and ω a measure in Ω. We present a unified theory of the Dirichlet problem and the Poisson equation. We prove the stability of the problem with respect to weak convergence of the data.


2017 ◽  
Vol 29 (8) ◽  
pp. 2030-2054
Author(s):  
Sorinel A. Oprisan

We used the phase-resetting method to study a biologically relevant three-neuron network in which one neuron receives multiple inputs per cycle. For this purpose, we first generalized the concept of phase resetting to accommodate multiple inputs per cycle. We explicitly showed how analytical conditions for the existence and the stability of phase-locked modes are derived. In particular, we solved newly derived recursive maps using as an example a biologically relevant driving-driven neural network with a dynamic feedback loop. We applied the generalized phase-resetting definition to predict the relative-phase and the stability of a phase-locked mode in open loop setup. We also compared the predicted phase-locked mode against numerical simulations of the fully connected network.


Author(s):  
M. D. Groves ◽  
E. Wahlén

We present an existence and stability theory for gravity–capillary solitary waves with constant vorticity on the surface of a body of water of finite depth. Exploiting a rotational version of the classical variational principle, we prove the existence of a minimizer of the wave energy𝓗subject to the constraint𝓘= 2µ, where𝓘is the wave momentum and 0 <µ≪ 1. Since𝓗and𝓘are both conserved quantities, a standard argument asserts the stability of the setDµof minimizers: solutions starting nearDµremain close toDµin a suitably defined energy space over their interval of existence. In the applied mathematics literature solitary water waves of the present kind are described by solutions of a Korteweg–de Vries equation (for strong surface tension) or a nonlinear Schrödinger equation (for weak surface tension). We show that the waves detected by our variational method converge (after an appropriate rescaling) to solutions of the appropriate model equation asµ↓ 0.


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