scholarly journals PHYSICAL ACTIVITY IN EARLY AND MIDDLE ADULTHOOD PREDICTS LATER-LIFE MEMORY TRAJECTORIES VIA HEALTH PATHWAYS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S900-S900
Author(s):  
Zarina Kraal ◽  
Laura B Zahodne
Keyword(s):  
Physical Activity ◽  
Life Course ◽  
Physical Inactivity ◽  
Mail Survey ◽  
Later Life ◽  
Study Entry ◽  
Latent Growth Curves ◽  
Metabolic Equivalents ◽  
Dementia Risk

Abstract Physical inactivity measured during late-life is a modifiable risk factor for dementia, but many studies use concurrent assessments with limited longitudinal follow-up. Less is known regarding life course exposure to physical inactivity. Physical activity patterns at different ages may make independent contributions to dementia risk, which would point to multiple critical periods for intervention. Using Health and Retirement Study Life History Mail Survey data (N=4,396), latent growth curves tested whether retrospectively-reported activity in early (18-29 years) and middle (40-49 years) adulthood predicted later-life memory trajectories over 18 years (mean age at study entry = 60.56 ± 5.44; mean follow-up = 13.27 ± 4.03 years). Total metabolic equivalents were computed from reports of moderate and vigorous physical activity. Biennial memory performance was modeled from study entry (between 1996 and 2014) to 2014. Self-reported physical and mental health at study entry were modeled as independent mediators. Models were adjusted for age at study entry, sex, education, race, ethnicity, childhood socio-economic status, year of study entry, and year of mail survey enrollment. More physical activity at ages 18-29 and 40-49 were independently associated with better initial memory, but not subsequent memory change. The association between physical activity at ages 40-49 and initial memory was partially mediated by better mental and physical health. These observational results support the possibility that physical activity interventions during multiple stages of the adult life course might be effective at lowering dementia risk. In particular, mid-life physical activity may have broad effects on later mental, physical, and cognitive health.

scholarly journals Physical Activity in Early- and Mid-Adulthood Are Independently Associated With Longitudinal Memory Trajectories in Later Life

2020 ◽  
Author(s):  
A Zarina Kraal ◽  
Hailey L Dotterer ◽  
Neika Sharifian ◽  
Emily P Morris ◽  
Ketlyne Sol ◽  
...  
Keyword(s):  
Physical Activity ◽  
Early Adulthood ◽  
Mail Survey ◽  
Growth Curves ◽  
Later Life ◽  
Critical Periods ◽  
Memory Decline ◽  
Latent Growth Curves ◽  
Cardiometabolic Diseases ◽  
Dementia Risk

Abstract Background Physical activity (PA) in later life may reduce dementia risk, but little is known regarding long-term cognitive effects of PA that occurred earlier in adulthood or mechanisms underlying associations. PA patterns at different ages may independently contribute to dementia risk, which would implicate multiple critical periods for intervention. The current study tested whether retrospective reports of PA in early and mid-adulthood were independently associated with later-life longitudinal memory outcomes and whether associations were mediated by late-life cardiometabolic diseases. Method Participants comprised 5200 Health and Retirement Study Life History Mail Survey respondents. Latent growth curves estimated independent associations between retrospectively reported PA in early adulthood (age 18–29) and mid-adulthood (age 40–49) and 16-year episodic memory trajectories. Indirect pathways involving the maintenance of PA from early- to mid-adulthood and the influence of PA on later-life cardiometabolic diseases (hypertension, diabetes, and heart disease) were also estimated. Results PA in early- and mid-adulthood independently predicted higher initial memory level and slower memory decline in later life, respectively. Early-adulthood PA was indirectly associated with later-life memory level through higher mid-adulthood PA and lower rates of later-life hypertension, as well as with subsequent memory decline through higher mid-adulthood PA. Conclusions The current findings highlight the importance of PA throughout adulthood, such that initiating and/or maintaining exercise in early- or mid-adulthood may be protective for later-life cognitive health, and hypertension appears to represent a key mediator of these effects.

scholarly journals Tracking of Maternal Physical Activity and Sport Participation over 11 Years: Findings from the Czech ELSPAC Study

2022 ◽  
Vol 19 (2) ◽  
pp. 705
Author(s):  
Mario Kasović ◽  
Lovro Štefan ◽  
Pavel Piler ◽  
Martin Zvonar
Keyword(s):  
Physical Activity ◽  
Risk Factor ◽  
Strength Training ◽  
Generalized Estimating Equations ◽  
Physical Inactivity ◽  
Sport Participation ◽  
Team Sports ◽  
Racket Sports ◽  
Structured Questionnaire

Purpose: Tracking of physical activity (PA) and sport participation (SP) during motherhood is poorly understood. The purpose of the study was to analyze the extent of tracking of maternal PA and SP. Methods: In this investigation, data were collected from the Czech ELSPAC study subsample of 4811 and 2609 women measured postnatally (1991–1992) and after 11 years of follow-up (2002–2003), respectively. The structured questionnaire was used to assess the participation and average weekly time spent in PA, and the frequency of engaging in different sports (running, cycling, strength training, racket sports, swimming, and team sports). Tracking was calculated using generalized estimating equations (GEE) with beta coefficients (β), odds ratios (ORs), and 95% confidence intervals (95% CI). Results: Moderately high tracking coefficients were observed for cycling (β = 0.69, 95% 0.67–0.72), strength training (β = 0.59, 95% 0.56–0.63), and weekly time spent in PA (β = 0.53, 95% 0.38–0.66); meanwhile, moderate tracking coefficients were generated for swimming (β = 0.48, 95% 0.44–0.52), team sports (β = 0.44, 95% 0.39–0.48), racket sports (β = 0.44, 95% 0.39–0.48), and running (β = 0.35, 95% 0.30–0.40). Mothers who did not participate in PA at baseline were 81% more likely not to participate in it at follow-up (OR = 1.81, 95% CI 1.53–2.13). Conclusion: Cycling- and strength-related activities and weekly PA were tracked moderately-to-moderately high during motherhood. Moreover, the strong tracking of physical inactivity indicates that the detection of this risk factor before pregnancy should be advocated.

Abstract P199: Keep Moving, Your Health Depends On It: Impact Of Improved Physical Activity And Weight Loss In A Wellness Program

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Ebenezer T Oni ◽  
Ehimen Aneni ◽  
Maribeth Rouseff ◽  
Thinh Tran ◽  
Henry Guzman ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Weight Loss ◽  
Intervention Program ◽  
South Florida ◽  
Metabolic Equivalents ◽  
Baseline Weight ◽  
The Mean ◽  
The Difference

Negative impact of CVD as the leading cause of death in the US is worsened by the significant burden of obesity and associated morbidity and concerns about the growing population inactivity. The American Heart Association has emphasized worksite-based interventions to improve CV health. We evaluated the benefits of improved physical activity(PA) and weight loss(WL) among employees of the Baptist Health South Florida enrolled in a wellness intervention program. Methods: Employees with two or more Cardio-metabolic risk factors , such as total cholesterol ≥ 200 mg/dl, systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg, hemoglobin A1C ≥ 6.5%, and body mass index (BMI) ≥ 30 were enrolled in an intervention program themed “My unlimited potential”. Interventions were focused on diet and PA modifications. We defined improved physical activity as the difference in the metabolic equivalents (METs) at 12 weeks follow-up and at baseline. WL (lbs) was the difference in weight at follow-up. The relationship between WL and changes in METs was explored in an ordered logistic regression. Results: Overall 203 (48±10 years, 78% females) employees were enrolled with a retention rate of 89% (n=181) at 12 weeks follow-up. At baseline the median weights was 211 lbs., and mean METs- 8.6, while at follow-up the median weight was 200 lbs, and the mean METs 11. At 12 weeks follow up 38% had significant WL (lost >5% of baseline weight). The median WL was 8.4 (IQR 4.8-13.0) lbs and the mean change in METs was 2.4±1.8. Median WL increased with increasing tertiles of METs change; tertile1- 6.5(4-11) lbs., tertile2- 9(6-13)lbs. tertile3- 11(7-15)lbs. Increased PA was related to increased WL across BMI categories adjusting for age, gender and baseline weight. Conclusion: This study points strongly toward the benefit of increasing PA among other lifestyle modification interventions in controlling weight. Although further follow-up of this population to evaluate sustainability of change is needed, our results clearly relate improved PA and health.

A life course approach for understanding later life sustainability

2017 ◽  
pp. 103-110
Author(s):  
Holly Syddall ◽  
Avan Aihie Sayer
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Life Course ◽  
Grip Strength ◽  
Optimal Strategies ◽  
Later Life ◽  
Present Evidence ◽  
Considerable Evidence ◽  
Life Course Approach ◽  
The Life Course

This chapter describes a life course approach for understanding later life sustainability, focusing on grip strength as a marker of physical sustainability, and explaining how a life course approach recognizes that muscle strength in later life reflects not only rate of loss in later life, but also the peak attained earlier in life. We present evidence that risk factors operating throughout the life course have an impact on physical sustainability in later life with particular consideration of the effects of body size, socioeconomic position, physical activity, diet, and smoking. We have shown that low birth weight is associated with weaker grip strength across the life course and that there is considerable evidence for developmental influences on ageing skeletal muscle. Finally, a life course approach suggests opportunities for early intervention to promote later life physical sustainability; but optimal strategies and timings for intervention are yet to be identified.

Tracking of physical activity during middle school transition in Iranian adolescents

2011 ◽  
Vol 71 (6) ◽  
pp. 631-641 ◽  
Author(s):  
Parvaneh Taymoori ◽  
Tanya R Berry ◽  
David R Lubans
Keyword(s):  
Physical Activity ◽  
High School ◽  
Physical Inactivity ◽  
Physical Activity Behavior ◽  
Self Report ◽  
Psychological Variables ◽  
Interpersonal Influences ◽  
Factors Analysis ◽  
Activity Behavior

Objective: The purpose of this longitudinal study was to examine changes in physical activity behavior, psychological factors and interpersonal influences associated with exercise behavior during the transition from secondary school to high school in Sanandaj, Iran. Design: Data were collected from students in 2006 ( N = 1,073), of whom 844 provided follow-up data in 2009. Setting: The students were in high school in 2009 (51% male) with a mean age of 16.42 ± 1.73 years. Method: Physical activity-related cognitions, interpersonal influences, and physical activity behavior were measured using self-report questionnaires. To assess the effects of time and sex on psychosocial factors, analysis of variances (ANOVAs) were conducted. The relative stability of physical activity psychosocial correlates from wave 1 through wave 2 was assessed using Pearson product-moment correlations. Results: There were significant differences according to sex across time for physical activity, psychological variables and interpersonal influences associated with exercise activities. The girls were less active than boys at both time points. Girls reported lower self-efficacy and perceived more barriers and fewer perceived benefits for physical activity over time. Interpersonal influences on activity were more stable for girls than boys. Conclusion: The results offer evidence for decreasing physical activity in boys and girls and sex differences in cognitive variables and interpersonal influences. This is important for understanding how to address the problem of physical inactivity among Iranian youth.

scholarly journals Association between physical activity levels in mid-life with physical activity in old age: a 20-year tracking study in a prospective cohort

BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e017378 ◽  
Author(s):  
Daniel Aggio ◽  
Olia Papacosta ◽  
Lucy Lennon ◽  
Peter Whincup ◽  
Goya Wannamethee ◽  
...  
Keyword(s):  
Physical Activity ◽  
Old Age ◽  
Sport Participation ◽  
Intraclass Correlation ◽  
Sports Participation ◽  
Later Life ◽  
Kappa Statistics ◽  
Activity Levels ◽  
Recreational Activity

ObjectivesThis study aims to examine the tracking and predictability of physical activity in old age from overall physical activity and participation in sport, recreational activity and walking in mid-life.DesignProspective population-based cohort study.SettingBritish Regional Heart Study participants recruited from primary care centres in the UK in 1978–1980.Participants and outcome measuresMen (n=3413) self-reported their physical activity at baseline, 12, 16 and 20-year follow-ups and were categorised as inactive or active and having high or low participation in sport, walking and recreational activities. Tracking was assessed using kappa statistics and random effects models. Logistic regression estimated the odds of being active at 20-year follow-up according to physical activity participation in mid-life.ResultsAmong 3413 men (mean age at baseline 48.6±5.4 years) with complete data, tracking of overall physical activity was moderate (kappa: 0.23–0.26). Tracking was higher for sports participation (kappa: 0.35–0.38) compared with recreational activity (kappa: 0.16–0.24) and walking (kappa: 0.11–0.15). Intraclass correlation coefficients demonstrated similar levels of stability and only marginally weakened after controlling for covariates. Compared with inactive men, being active at baseline was associated with greater odds of being active at 20-year follow-up (OR 2.7, 95% CI 2.4 to 3.2) after adjusting for sociodemographic, health and lifestyle variables. Playing sport in mid-life was more strongly associated with being active at 20-year follow-up than other domains, particularly when sport participation began earlier in life.ConclusionBeing physically active in mid-life increases the odds of being active in old age. Promoting physical activity in later life might be best achieved by promoting sport participation earlier in the life course.

Multimorbidity, mortality, and physical activity

2016 ◽  
Vol 12 (4) ◽  
pp. 272-280 ◽  
Author(s):  
Paul D Loprinzi ◽  
Ovuokerie Addoh ◽  
Chelsea Joyner
Keyword(s):  
Physical Activity ◽  
Mortality Risk ◽  
Physical Inactivity ◽  
Self Report ◽  
Minimal Effect ◽  
Increased Risk ◽  
All Cause Mortality ◽  
The Government ◽  
Physician Diagnosis

Objectives Multimorbidity and physical inactivity are individually associated with increased mortality risk, but the possibility for physical activity to moderate the multimorbidity–mortality relationship has yet to be investigated. Methods Data from the 1999–2006 NHANES were employed, with 16,091 participants constituting the analytic sample. Participants were followed through 2011, including a median follow-up of 99 months. Physical activity was assessed via self-report with multimorbidity assessed from physician diagnosis. Results After adjustment, for every 1 morbidity increase, participants had a 23% increased risk of all-cause mortality (HR = 1.23; 95% CI: 1.19–1.28; p < 0.001). Multimorbidity mostly remained associated with all-cause mortality across all levels of physical activity, with the exception of those achieving four times the dose of the government guidelines. Discussion With the exception of those who engaged in high levels of self-reported physical activity, physical activity had a minimal effect on the multimorbidity–mortality relationship.

scholarly journals Do Life Course Physical Activity Profiles Reduce the Effects of Childhood Exposures on Cognition?

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 29-29
Author(s):  
Monica Williams-Farrelly ◽  
Jacqui Smith
Keyword(s):  
Physical Activity ◽  
Life Course ◽  
Healthy Aging ◽  
Latent Class ◽  
Mail Survey ◽  
Learning Problems ◽  
Average Reference ◽  
Curve Modeling ◽  
The Relationship ◽  
Retirement Study

Abstract Although physical activity throughout life is one of the most reliable predictors of healthy aging, can less consistent or favorable trajectories also improve cognition trajectories among older adults? Drawing from accumulation theories, we use longitudinal data from the Health and Retirement Study and Life History Mail Survey (N=9,309) to examine the early antecedents of cognitive decline and the extent to which different life course physical activity profiles can slow such a decline. Results from latent class analysis reveal seven distinct profiles: consistently low, consistently high, consistently average (reference), improvers, decliners, midlife motivators, and previously athletic “couch potatoes.” Growth curve modeling analyses show that membership in the consistently high class and midlife motivators were associated with better cognition initially and over time, with no difference between the two classes. Additionally, though poor health and learning problems in childhood were associated with worse initial cognition, physical activity does not mediate the relationship.

A Prospective Examination of the Relationship between Physical Activity and Dementia Risk in Later Life

2012 ◽  
Vol 26 (6) ◽  
pp. 333-340 ◽  
Author(s):  
Mary Elizabeth Bowen
Keyword(s):  
Physical Activity ◽  
Model Building ◽  
Vigorous Physical Activity ◽  
Later Life ◽  
Cognitive Outcome ◽  
Dementia Diagnosis ◽  
Activity Data ◽  
Dementia Risk ◽  
Prospective Study Design ◽  
The Relationship

Purpose. To examine the relationship between vigorous physical activity and dementia risk. Design. Prospective study design utilizing physical activity data from the Health and Retirement Study and cognitive outcome data from the Aging, Demographics, and Memory Study. Setting. Community-based. Subjects. Adults age 71 and over (N = 808) with 3 to 7 years of physical activity information prior to dementia/no dementia diagnosis. Measures. Physical activity was measured by participation in vigorous activities such as aerobics, sports, running, bicycling, and heavy housework three or more times per week (yes/no). Dementia diagnosis was based on an expert panel (e.g., neuropsychologists, neurologists, geropsychiatrists) who performed and reviewed a battery of neuropsychological tests. Analysis. Binary logistic regression models were used to account for demographic characteristics, genetic risk factors (one or two apolipoprotein E ε4 alleles), health behaviors (e.g., smoking, drinking alcohol), health indicators (body mass index), and health conditions (e.g., diabetes, heart disease) in a sequential model-building process. Results. The relationship between vigorous physical activity and dementia risk remained robust across models. In the final model, older adults who were physically active were 21% (p ≤ .05) less likely than their counterparts to be diagnosed with dementia. Conclusion. Vigorous physical activity may reduce the risk for dementia independently of the factors examined here. This study's findings are important given that few preventative strategies for dementia have been explored beyond hormonal therapy and anti-inflammatory drugs.

Independent effects of waist circumference and physical activity on all-cause mortality in Canadian women

2006 ◽  
Vol 31 (3) ◽  
pp. 271-276 ◽  
Author(s):  
Peter T Katzmarzyk ◽  
Cora L Craig
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Waist Circumference ◽  
Physical Inactivity ◽  
Proportional Hazards ◽  
Leisure Time Physical Activity ◽  
Smoking Status ◽  
Cox Proportional Hazards ◽  
Independent Effects

The purpose of this study was to determine the independent effects of waist circumference (WC) and physical inactivity on the risk of mortality in women. This prospective cohort study included 5421 female participants 20-69 years of age in the 1981 Canada Fitness Survey. WC was measured with an anthropometric tape and leisure-time physical activity levels over the previous 12 months were assessed with a questionnaire. Mortality surveillance was conducted by data linkage with the Canadian Mortality Database through 31 December, 1993. The hazard ratios (HR) of mortality were estimated using Cox proportional hazards regression with age, smoking status, and alcohol con sumption included as covariates in all models. A total of 225 deaths occurred over an average of 12.4 years of follow up (67 500 person-years of follow up). Physical activity (HR = 0.78; 95% C.I.: 0.64-0.95) and WC (HR = 1.17; 95% C.I.: 1.05-1.31) were associated with mortality when included in separate regression models. When included in the same model, both physical activity (HR = 0.79; 95% CI: 0.65-0.96) and WC (HR = 1.16; 95% C.I.: 1.04-1.30) remained independent significant predictors of mortality. In conclusion, physical inactivity and high WC have significant independent risks of premature mortality among women.Key words: death, obesity, cohort study, Canada Fitness Survey.

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