scholarly journals Rethinking disease eradication: putting countries first

2021 ◽  
Vol 13 (3) ◽  
pp. 215-221
Author(s):  
Teshome Gebre

Abstract There have been various infectious disease eradication programs implemented in various parts of the world with varying degrees of success since the early 1900s. Of all those programs, the one that achieved monumental success was the Smallpox Eradication Program (SEP). Most of the global health leaders and authorities that came up with the new idea of disease eradication in the 1980s tried to design and shape the new programs based on their experience in the SEP. The SEP had a very effective tool, vaccine, that did not require a cold chain system, and a relatively simple way of administration. The total cost of the eradication program was about US$300 million and the entire campaign took about 10 y. However, the Guinea worm and polio eradication programs that followed in the footsteps of SEP attained varying levels of success, consuming a huge amount of resources and taking a much longer time (>30 y each). This paper reviews the factors that played major roles in hindering the attainment of eradication goals and outlines possible recommendations for the way forward. Among other things, this paper strongly emphasizes that endemic countries should take the lead in all matters pertaining to making decisions for disease elimination and/or eradication initiatives and that ‘elimination as a public health problem’ is the preferred option rather than going for complete eradication at the expense of other health programs and thereby contributing to weakening of already fragile health systems, mainly in Africa.

Author(s):  
Josu Doncel ◽  
Nicolas Gast ◽  
Bruno Gaujal

We analyze a mean field game model of SIR dynamics (Susceptible, Infected, and Recovered) where players choose when to vaccinate. We show that this game admits a unique mean field equilibrium (MFE) that consists in vaccinating at a maximal rate until a given time and then not vaccinating. The vaccination strategy that minimizes the total cost has the same structure as the MFE. We prove that the vaccination period of the MFE is always smaller than the one minimizing the total cost. This implies that, to encourage optimal vaccination behavior, vaccination should always be subsidized. Finally, we provide numerical experiments to study the convergence of the equilibrium when the system is composed by a finite number of agents ( $N$ ) to the MFE. These experiments show that the convergence rate of the cost is $1/N$ and the convergence of the switching curve is monotone.


2008 ◽  
Vol 29 (1) ◽  
pp. 59-66 ◽  
Author(s):  
Bich Huu Tran

Background Malnutrition is a public health problem in Vietnam. Child health and the status of women have been targets for various health programs in the country. In general, reports in the literature suggest that care is positively correlated with positive nutritional status of children. In the household, the father is considered a resource for care. However, the role of paternal care in health programs has not received the attention it deserves. Objective To identify associations between the involvement of fathers in child care and housework and the nutritional status of children under 3 years of age. Methods This cross-sectional study was based on a random sample of 547 children under 3 years of age from intact families and their biological parents. The main outcome variable was child nutrition. Predictor variables represented two domains of father's involvement. Multivariable general linear modeling and multivariable logistic regression modeling were performed with the use of a combination of stepwise and hierarchical approaches in data analysis. Results The overall prevalence of underweight among children was 19.1%, and the prevalence of stunting was 14.4%. Children whose fathers did not bring them to a medical facility for immunization were about 1.7 times more likely to be underweight and stunted than those whose fathers did bring them for immunization after child's age, household economic status, and mother's education were controlled for. Father's involvement in housework was not found to be related to the prevalence of malnutrition. Conclusions Paternal involvement in child immunization should be encouraged by health-care providers who manage immunization programs.


2018 ◽  
Vol 2 ◽  
pp. 30 ◽  
Author(s):  
Elizabeth A. Cromwell ◽  
Sharon Roy ◽  
Dieudonne P. Sankara ◽  
Adam Weiss ◽  
Jeffrey Stanaway ◽  
...  

Background:The objective of this study was to document the worldwide decline of dracunculiasis (Guinea worm disease, GWD) burden, expressed as disability-adjusted life years (DALYs), from 1990 to 2016, as estimated in the Global Burden of Disease study 2016 (GBD 2016). While the annual number of cases of GWD have been consistently reported by WHO since the 1990s, the burden of disability due to GWD has not previously been quantified in GBD.Methods:The incidence of GWD was modeled for each endemic country using annual national case reports. A literature search was conducted to characterize the presentation of GWD, translate the clinical symptoms into health sequelae, and then assign an average duration to the infection. Prevalence measures by sequelae were multiplied by disability weights to estimate DALYs.Results:The total DALYs attributed to GWD across all endemic countries (n=21) in 1990 was 50,725 (95% UI: 35,265–69,197) and decreased to 0.9 (95% UI: 0.5–1.4) in 2016. A cumulative total of 12,900 DALYs were attributable to GWD from 1990 to 2016.Conclusions:Using 1990 estimates of burden propagated forward, this analysis suggests that between 990,000 to 1.9 million DALYs have been averted as a result of the eradication program over the past 27 years.


2015 ◽  
Vol 3 (2) ◽  
pp. 248
Author(s):  
Grasiano Warakano Lailossa

The differences In cold chain system, Risk analysis and Hazard Analysis and Critical Crisis Point(HACCP) is a procedure for the identification, assessment and control of hazards in, and indirectly risks from, food. HACCP procedures focus on chemical, physical and microbiological hazards, Yellow Fin Tuna is the one of the most superior export fishery product of Moluccas, based on paper review and field observation in Molucass, this paper is a preliminary study to development HACCP framework of frozen Yellow Fin Tuna in Moluccas.


2021 ◽  
Author(s):  
Romain LAN ◽  
Fabrice CAMPANA ◽  
Delphine TARDIVO ◽  
Jean-Hugues CATHERINE ◽  
Jean-Noel VERGNES ◽  
...  

Abstract Background: Tobacco and alcohol are the main risk factors for oral squamous cell carcinoma, the low survival rate of which is a public health problem. European-wide health policies (prevention campaign, tobacco packaging) have been put in place to inform the population of the risks associated with their consumption. Due to the increase in smoking among women and changes in sexual practices, the incidence of this disease is still too high. The identification of data from internet research on the population could make it possible to measure the impact and better orient these preventive measures.The objective was to analyse the data on interest shown in oral cancers from several online databases, and to cross-reference them with the data on the introduction of European public health programs.Methods: A search of data from Google ©, Wikipedia © and Twitter © users in 28 European countries relating to oral cancer between 2004 and 2019 was carried out. Bibliometric analysis of press and scientific articles over the same period was also analysed. The association between these data and the introduction of public health programs in Europe has been studied.Results: Changes in tobacco packaging correlated with a significant increase in internet research on oral cancer in 7 countries. Unlike national policies and campaigns, the European awareness program Make Sense has had no influence on internet research. There was an asymmetric correlation in internet searches between publications on oral cancer from scientific articles or "traditional" media (weak association) and those from internet media such as Twitter © or Wikipedia © (strong association).Conclusion: Our work highlights 7 areas of work around which oral cancer awareness in Europe could be refocused.


Author(s):  
Sumit Arun Hirve ◽  
Pradeep Reddy C. H.

Being premature, the traditional data visualization techniques suffer from several challenges and lack the ability to handle a huge amount of data, particularly in gigabytes and terabytes. In this research, we propose an R-tool and data analytics framework for handling a huge amount of commercial market stored data and discover knowledge patterns from the dataset for conveying the derived conclusion. In this chapter, we elaborate on pre-processing a commercial market dataset using the R tool and its packages for information and visual analytics. We suggest a recommendation system based on the data which identifies if the food entry inserted into the database is hygienic or non-hygienic based on the quality preserved attributes. For a precise recommendation system with strong predictive accuracy, we will put emphasis on Algorithms such as J48 or Naive Bayes and utilize the one who outclasses the comparison based on accuracy. Such a system, when combined with R language, can be potentially used for enhanced decision making.


2020 ◽  
Vol 48 (1) ◽  
Author(s):  
Mahboubeh Khaton Ghanbari ◽  
Hasan Abolghasem Gorji ◽  
Masoud Behzadifar ◽  
Nadia Sanee ◽  
Nafiul Mehedi ◽  
...  

Abstract Background Brucellosis is the most significant and common bacterial zoonosis and is recognized as a re-emerging and neglected disease. Tackling zoonosis is very important for the health and the economy. One Health is an approach characterized by the integration of human and animal health, plants, and ecosystems and encourages joining local, national, and global multidisciplinary efforts to achieve optimal levels of health and collaboration among different disciplines to address complex health problems. Objectives The present study aimed to review published scientific literature related to the use of the One Health approach to tackle human brucellosis. Methods Web of Science (WoS), PubMed, Scopus, The Cochrane Library, and Embase databases were searched from inception until 30 January 2020. The reference lists of all relevant papers were hand-searched. Two authors extracted data from published studies independently. The Joanna Briggs Institute tool was used to assess the quality of studies. Results Of 2297 studies, 10 studies were deemed eligible, which were conducted between 2013 and 2019. Studies were performed in Uganda, Malta, Serbia, Greece, Mongolia, Azerbaijan, Israel, India, Ethiopia, and the USA. All studies suggested that brucellosis is still a major public health problem and that the most important aspect of the One Health approach is the interdependence of humans, ecosystems, and animals .Some studies have focused on livestock vaccination as the most effective way to prevent disease, and others have focused on the biology of Brucella infection and its transmission patterns. Some studies have pointed to the effectiveness of the One Health approach in all the phases of disease management as well as to its role in reducing health costs. Conclusion The success of the approach depends on the willingness of the decision-makers to implement the necessary policies. Due to the heterogeneity of current practices, and organizations involved in One Health approach-based programs, it will be incomplete without proper planning. To better implement the approach, strategies should be appraised and disseminated by experts and relevant stakeholders.


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