333 Assessment of Spent Hemp Biomass as a Potential Feedstuff in Ruminant Diets

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 185-186
Author(s):  
Nathan Parker ◽  
Hunter Ford ◽  
Massimo Bionaz ◽  
Erminio Trevisi ◽  
Serkan Ates
Keyword(s):  
Feed Intake ◽  
Cannabis Sativa ◽  
Plasma Cholesterol ◽  
Animal Health ◽  
Agricultural Product ◽  
Health Production ◽  
Farm Bill ◽  
Ruminant Diets ◽  
Second Period

Abstract The 2018 Farm Bill removed hemp (Cannabis sativa) from the Controlled Substances Act, classifying it as an agricultural product. The process of cannabidiol extraction from hemp yields large quantities of spent hemp biomass (SHB) that may potentially be included in animal diets. However, the use of SHB in animal diets has not been approved by FDA yet since its effect on animal health, production and product quality is still unknown. Thus, a feeding study was carried out to investigate the effects of varying levels of SHB and a four-week withdrawal period on feed intake and liveweight gains of weaned lambs. A total of 35 weaned, male Polypay lambs kept in single pens were randomly assigned to five feeding treatments (n=7) and fed diets containing either no SHB (CON) or SHB at 10% (LH1) or 20% (HH1) for 4 weeks with 4 weeks withdrawal from SHB, or SHB at 10 (LH2) or 20% (HH2) for 8 weeks. The nutritive analysis of the SHB indicated a high-quality feed, with 20% (DM) crude protein and 27% NDF. Dry matter (DM) intake of lambs was negatively affected by 20% SHB during the first period. In the second period, DM intake was larger in lambs fed 10% SHB vs. CON, with the largest feed intake observed in HH1 lambs. In contrast, none of the performance data, including liveweight gains, were different across the groups and periods. Feeding 20% SHB decreased plasma cholesterol, NEFA, BHBA, Ca, and Cl and increased urea and Mg, while 10% SHB increased glucose, cholesterol, and NEFA. Our findings indicated that 10% SHB can be included in ruminant diets without causing any detrimental effect on performance with a possible positive effect on feed intake. The long-term feeding of 20% SHB strongly affects the metabolism.

Gestational exposure to Δ9-THC impacts ovarian follicular dynamics and angiogenesis in adulthood in Wistar rats

2021 ◽  
pp. 1-5
Author(s):  
Annia A. Martínez-Peña ◽  
Kendrick Lee ◽  
James J. Petrik ◽  
Daniel B. Hardy ◽  
Alison C. Holloway
Keyword(s):  
Reproductive Health ◽  
Cannabis Sativa ◽  
Follicular Development ◽  
Angiogenic Factor ◽  
Postnatal Life ◽  
Adult Rat ◽  
Female Reproductive Health ◽  
Gestational Exposure ◽  
Follicular Dynamics

Abstract With the legalization of marijuana (Cannabis sativa) and increasing use during pregnancy, it is important to understand its impact on exposed offspring. Specifically, the effects of Δ-9-tetrahydrocannabinol (Δ9-THC), the major psychoactive component of cannabis, on fetal ovarian development and long-term reproductive health are not fully understood. The aim of this study was to assess the effect of prenatal exposure to Δ9-THC on ovarian health in adult rat offspring. At 6 months of age, Δ9-THC-exposed offspring had accelerated folliculogenesis with apparent follicular development arrest, but no persistent effects on circulating steroid levels. Ovaries from Δ9-THC-exposed offspring had reduced blood vessel density in association with decreased expression of the pro-angiogenic factor VEGF and its receptor VEGFR-2, as well as an increase in the anti-angiogenic factor thrombospondin 1 (TSP-1). Collectively, these data suggest that exposure to Δ9-THC during pregnancy alters follicular dynamics during postnatal life, which may have long-lasting detrimental effects on female reproductive health.

scholarly journals A comparative two-cohort study of pediatric patients with long term stay in ICUs

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Julia García Mancebo ◽  
Sara de la Mata Navazo ◽  
Estíbaliz López-Herce Arteta ◽  
Rosario Montero Mateo ◽  
Isabel María López Esteban ◽  
...  
Keyword(s):  
Healthcare Resources ◽  
Non Invasive ◽  
Non Invasive Ventilation ◽  
Number Of Patients ◽  
Single Center Study ◽  
High Flow Oxygen ◽  
Hospital Acquired ◽  
Complications And Mortality ◽  
Second Period

AbstractDuring the last decades, the number of patients with long stay admissions (LSA) in PICU has increased. The purpose of this study was to identify factors associated with PICU LSA, assessing healthcare resources use and changes in the profile of these patients. A retrospective, observational, single-center study was carried out. Characteristics of LSA were compared between two periods (2006–2010 and 2011–2015). During the earlier period there were 2,118 admissions (3.9% of them LSA), whereas during the second period, there were 1,763 (5.4% of them LSA) (p = 0.025). LSA accounted for 33.7% PICU stay days during the first period and 46.7% during the second (p < 0.001). Higher use of non-invasive ventilation (80.2% vs. 37.8%, p = 0.001) and high-flow oxygen therapy (68.8% vs. 37.8%, p = 0.005) was observed in the 2011–2015 cohort, whereas the use of arterial catheter (77.1% vs. 92.6%, p = 0.005), continuous infusion of adrenaline (55.2% vs. 75.9%, p = 0.004), and hemoderivative transfusion (74% vs. 89.2%, p = 0.010) was less frequent. In the 2006–2010 cohort, hospital-acquired infections were more common (95.2% vs. 68.8%, p < 0.001) and mortality was higher (26.8% vs. 13.8%, p = 0.026). The number of long-stay PICU admissions have increased entailing an intensive use of healthcare resources. These patients have a high risk for complications and mortality.

scholarly journals Water intake of pigs consuming tiamulin during the nursery phase1

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Kimberly A Vonnahme ◽  
Adam Mueller ◽  
Daniel A Nelson ◽  
Manuel Alexander Vasquez-Hidalgo ◽  
Deborah Amodie ◽  
...  
Keyword(s):  
Drinking Water ◽  
Water Intake ◽  
Feed Intake ◽  
Animal Health ◽  
Average Daily Gain ◽  
Water System ◽  
Water Soluble ◽  
Daily Water Intake ◽  
Original Product ◽  
Effect Of Treatment

Abstract Mass medication to manage population health can be achieved by providing therapeutics in the drinking water. Young nursery pigs are highly sensitive to the flavor and smell of water. Medications that reduce water palatability often lead to an interruption in water and feed intake. With the availability of several generic water-soluble antimicrobials for pigs, questions have arisen about their palatability compared with the original product. In this study, we compared the intake of water containing tiamulin hydrogen fumarate from two different manufacturers with the intake of unmedicated water. The hypothesis was that the intake of tiamulin-containing water would be similar to unmedicated water. Water intake was monitored upon entry into the nursery and just prior to leaving the nursery. Also, average daily gain (ADG) and feed efficiency (FE) were determined. A total of 300 pigs were individually weighed (4.2–10.9 kg; avg = 6.8 kg) for randomization to pen (n = 30 pens). The experiment had two time points: 1) early nursery (periods 1–3) and 2) late nursery (period 4). Pens were randomly assigned to a sequence (period 1–3) in a crossover experimental design containing three 10-d periods, with 5 d for the resetting of baseline where unmedicated water was provided followed by 5 d on tiamulin source addition [i.e., TriamuloxTM (Zoetis, Parsippany, NJ); Denagard (Elanco Animal Health, Greenfield, IN)] or unmedicated water. After period 3 was concluded, all pens were given unmedicated water (via nipple waterers) and the number of pigs per pen was reduced to six pigs to maintain adequate space per pig. Ten days prior to pigs leaving the nursery, a fourth period was performed. After a 5-d water baseline was achieved, pens were treated with either unmedicated water or Triamulox- or Denagard-containing water. Pigs had ad libitum access to water and feed. During the testing periods, daily water intake was measured by a cup water system in each pen. Feed intake was measured every 5 d. There was no effect of treatment on initial body weights or weights at the beginning or end of each period (P ≥ 0.51). Therefore, there was no effect of treatment on ADG (P ≥ 0.23). Water intake (P ≥ 0.16) and FE (P ≥ 0.35) were not affected by treatment. Water consumption was similar among all treatments in each of the four periods. There appears to be no aversion to water intake when tiamulin hydrogen fumarate is added to the drinking water.

Recording long-term feed intake using the X-ray method for selective breeding purposes in rainbow trout

Aquaculture ◽  
2007 ◽  
Vol 272 ◽  
pp. S274-S275
Author(s):  
A. Kause ◽  
D. Tobin ◽  
A. Dobly ◽  
D.F. Houlihan ◽  
S. Martin ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Feed Intake ◽  
Selective Breeding ◽  
Ray Method ◽  
X Ray

scholarly journals Monitoring of fish diseases in the Magadan region

2021 ◽  
Vol 36 ◽  
pp. 07008
Author(s):  
E.A. Vitomskova
Keyword(s):  
Pacific Salmon ◽  
Animal Health ◽  
Natural Populations ◽  
Clinical Signs ◽  
Commercial Fish ◽  
Fish Diseases ◽  
North East ◽  
Comparative Aspect ◽  
Different Seasons

In such a large region as the Far North-East of Russia, there is still no purposeful ichthyopathological study of fish diseases, which has epizootic and epidemiological significance. The material for the study was commercial fish caught in different seasons of 1995-2021. As a result of the research, individuals of natural populations and in aquaculture with clinical signs of infectious and parasitic diseases were found, and cultures of virulent strains of microorganisms were isolated. According to the results of the parasitological study, larvae of nematodes of the family Anisakidae and plerocercoids of cestodes Diphyllobothriidae, which have important epidemiological and epizootic significance, were registered. Based on long-term ichthyopathological studies, a retrospective review of own data was carried out. The analysis of infectious diseases of mature individuals of anadromous Pacific salmon of the genus Oncorhynchus, as well as long-term parasitological monitoring in a comparative aspect of the invasion of commercial fish by helminths dangerous to human and animal health, is presented.

scholarly journals Long-term and trans-generational effects of neonatal experience on sheep behaviour

2014 ◽  
Vol 10 (7) ◽  
pp. 20140273 ◽  
Author(s):  
Corinna Clark ◽  
Joanna Murrell ◽  
Mia Fernyhough ◽  
Treasa O'Rourke ◽  
Michael Mendl
Keyword(s):  
Early Life ◽  
Pain Sensitivity ◽  
Animal Health ◽  
Adult Life ◽  
Farm Animals ◽  
Important Species ◽  
Relative Paucity ◽  
Tail Docking ◽  
Generational Effects

Early life experiences can have profound long-term, and sometimes trans-generational, effects on individual phenotypes. However, there is a relative paucity of knowledge about effects on pain sensitivity, even though these may impact on an individual's health and welfare, particularly in farm animals exposed to painful husbandry procedures. Here, we tested in sheep whether neonatal painful and non-painful challenges can alter pain sensitivity in adult life, and also in the next generation. Ewes exposed to tail-docking or a simulated mild infection (lipopolysaccharide (LPS)) on days 3–4 of life showed higher levels of pain-related behaviour when giving birth as adults compared with control animals. LPS-treated ewes also gave birth to lambs who showed decreased pain sensitivity in standardized tests during days 2–3 of life. Our results demonstrate long-term and trans-generational effects of neonatal experience on pain responses in a commercially important species and suggest that variations in early life management can have important implications for animal health and welfare.

Long-term Administration of Cannabis sativa Impairs Learning and Memory in CD1 Mice

2015 ◽  
Vol 15 (3) ◽  
pp. 155-159
Author(s):  
V.E. Okon ◽  
A.O. Obembe ◽  
E.O. Ofutet ◽  
E.E. Osim
Keyword(s):  
Learning And Memory ◽  
Cannabis Sativa ◽  
Term Administration ◽  
Cd1 Mice

scholarly journals PSIX-39 Supplementing an immunomodulatory feed ingredient to improve thermoregulation and performance in finishing beef cattle under heat stress conditions

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 392-392
Author(s):  
Eduardo Colombo ◽  
Reinaldo F Cooke ◽  
Kelsey Schubach ◽  
Bruna Rett ◽  
Alice Brandão
Keyword(s):  
Heat Stress ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Treatment Effects ◽  
Bos Taurus ◽  
Animal Health ◽  
Plasma Concentrations ◽  
Experimental Period ◽  
Stress Conditions ◽  
Finishing Cattle

Abstract This experiment compared physiological and productive parameters in finishing cattle managed under heat stress conditions, and supplemented or not with Omnigen-AF (Phibro Animal Health, Teaneck, NJ). Crossbred cattle (Bos taurus × B. indicus; 64 heifers and 64 steers) were ranked by initial body weight (BW; 440 ± 3 kg) and sex, and allocated to 1 of 16 pens (8 heifers or steers/pen). Pens within sex were randomly assigned to receive (OMN; n = 8) or not (CON; n = 8) Omnigen-AF at 56 g/cow daily (as-fed basis). Cattle received a total-mixed ration during the experimental period (d 0 to 107), and Omnigen-AF was offered daily as a top-dress to OMN. Cattle were shipped on d 107 to a commercial packing facility for slaughter. Cattle BW was recorded and samples of blood and tail-switch hair collected on d 0, 28, 56, 84, and 106. Feed intake was evaluated biweekly from each pen, and feed efficiency calculated according to total feed intake and BW gain of each pen. From d 0 to 7, 28 to 42, and 84 to 98, heifer intravaginal temperature was recorded hourly (iButton temperature loggers DS1922L, Maxim Integrated, San Jose, CA). Environmental temperature humidity index (THI) was also recorded hourly throughout the experiment, and averaged 79.8 ± 0.6. Heifers receiving OMN had less (P &lt; 0.05) vaginal temperature from 1500 to 1900h (39.05 vs. 39.19 °C), when THI ranged from 85.3 to 90.1. No treatment effects were detected (P &gt; 0.20) for BW gain, feed intake, feed efficiency, and carcass traits. No treatment effects were also detected (P &gt; 0.17) for plasma concentrations of cortisol and haptoglobin, and cortisol concentrations in tail-switch hair. Hence, OMN ameliorated hyperthermia in finishing cattle exposed to heat stress conditions, but such benefit was not sufficient to improve productive and physiological responses.

The long-term accumulation and depletion of copper in the liver of different breeds of sheep fed diets of differing copper content

1983 ◽  
Vol 100 (2) ◽  
pp. 441-449 ◽  
Author(s):  
J. A. Woolliams ◽  
N. F. Suttle ◽  
G. Wiener ◽  
A. C. Field ◽  
C. Woolliams
Keyword(s):  
Copper Content ◽  
Rate Of Increase ◽  
Breed Differences ◽  
The Mean ◽  
Second Period ◽  
Mean Concentration ◽  
Period Measurement

SUMMARYChanges in Cu concentration in the livers of adult Scottish Blackface (B), Welsh Mountain (W) and B × W ewes fed diets containing 4, 9, 17 and 29 mg Cu/kg D.M. were measured over a 28-week period. Measurement continued during two further periods of 18 weeks when first all sheep were fed the diet containing 4 mg Cu/kg D.M. and finally, when 4 mg Mo/kg D.M. was added to this diet.During the first period the increase on all diets was least in B ewes and, apart from the 4 mg Cu/kg D.M. diet, greatest in W ewes; this difference increased as the Cu in the diet increased. The rate of increase for all ewes diminished towards the end of the period. All breed types retained proportionately less Cu in their livers as the Cu in the diet increased; at one extreme B ewes fed 17 or 29 mg Cu/kg D.M. retained equal amounts.When during the second period all sheep were fed the 4 mg Cu/kg D.M. diet the Cu concentration in their livers decreased, the rate of decrease being greatest for ewes whose mean concentration in the liver was highest, but at similar concentrations the decrease was greater in B than W ewes. During the final period the decrease was faster and was again associated with the mean Cu concentration, but the decrease was not significantly affected by breed.Throughout the trial, W ewes had the highest concentration of Cu in their plasma, whilst B ewes and ewes fed the 4 mg Cu/kg D.M. diet throughout had the lowest concentrations both in plasma and in their kidneys at slaughter.The results show that breeds differ in their ability to retain Cu from the diet in their livers. The magnitude of these differences depends on the intake of Cu and Mo from the diet and is affected by the concentration of Cu in the liver. Breed differences in the absorption and endogenous loss of Cu are suggested.

scholarly journals Economic impact of cross compliance in the field of animal welfare (Acts C18 and C16)

2015 ◽  
Vol 10 (1s) ◽  
Author(s):  
Marisanna Speroni ◽  
Maurizio Capelletti ◽  
Antonio Bruni ◽  
Luigi Degano
Keyword(s):  
Animal Welfare ◽  
Economic Impact ◽  
Animal Health ◽  
Animal Husbandry ◽  
Market Prices ◽  
Management Actions ◽  
Public Grant ◽  
Cattle Farms ◽  
Cross Compliance

The paper reports the results of assessment of animal welfare at farm level on two dairy cattle farms, identification of structural and management actions to improve the animal welfare and estimate of the costs of such actions; furthermore the economic impact of the potential support under measure 215 of the Rural Development Plan was also simulated. At the time of assessment, no severe break of compliance was detected at the two farms; however some weaknesses were identified and improvement were proposed in order to maintain the current animal welfare status and avoid future failures. The two use cases showed that investments to improve animal welfare were partly self funded in the mid and long term due to the higher milk yield and the better animal health that were expected as consequence; however, in the short term, a large part of expenses was fully borne by farmers if not supported by a public grant or higher market prices. The support provided by the measure 215 is effective in rewarding farmers who undertake to adopt standards of animal husbandry which go beyond the relevant mandatory standards.

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