scholarly journals 19 Effects of glutathione on growth performance and intestinal health of piglets

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 19-19
Author(s):  
Xianyong Ma ◽  
Zhimei Tian ◽  
Yiyan Cui ◽  
Zhichang Liu ◽  
Huijie Lu
Keyword(s):  
Growth Performance ◽  
Average Daily Gain ◽  
Control Group ◽  
Standard Diet ◽  
Intestinal Health ◽  
Large White ◽  
Crypt Depth ◽  
Mda Content ◽  
Villous Height ◽  
Mucosal Morphology

Abstract Object: The aim of this experiment was to study the effects of different levels of glutathione (GSH) on growth performance and intestinal health of piglets. Methods: A total of 180 piglets of 21-day-old (Duroc × Landrace × Large White) were randomly divided into 5 groups. The control group was fed a standard diet based on NRC 2012. The treatment group 1 - 4 was supplemented with 50, 100, 200 and 400mg/kg GSH. The experiment lasted 28 days. Results: Compared with the control group, 50mg/kg GSH significantly increased the piglet’s skin and gross color, average daily gain (ADG) and decreased feed gain ratio (F/G) (P < 0.05), while the effect of 100, 200, 400 mg/kg GSH was contrary. The supplementation of 50mg/kg GSH significantly increased the mucosal villi height, the ratio of villous height to crypt depth (VH/CD) and decreased the crypt depth (P < 0.05) in duodenum, jejunum and ileum (P < 0.05), while the effect of 100, 200, 400 mg/kg GSH was contrary; The supplementation of 50mg/kg GSH decreased the concentration of triglyceride in plasma (P < 0.05); The supplementation of 50, 100, 200, 400mg/kg GSH had no effect on the antioxidative indexes of blood, but 400mg/kg GSH increased the activities of T-AOC, GSH, SOD and decreased MDA content in jejunum and ileum; 400mg/kg GSH increased the content of T-SOD in liver (P < 0.05), while 50mg/kg GSH had no effect on SOD, GSH-PX, GSH-SOD in intestine and liver (P > 0.05). 50mg/kg GSH significantly increased T-AOC activity and decreased MDA content in muscle (P < 0.05). Conclusion: Supplementation of 50mg/kg GSH in piglets` diet was the most appropriate and it could significantly improve skin and gross color, growth performance and intestinal mucosal morphology, it also increased the antioxidation ability in muscle of piglets.

scholarly journals Effects of Yucca Shidigera Extract and Candida Utilis on Growth Performance and Intestinal Health of Weaned Piglets

2020 ◽  
Author(s):  
Zhenguo Yang ◽  
Yao Wang ◽  
Tianle He ◽  
Ziema Bumbie Gifty ◽  
Zhihong Sun ◽  
...  
Keyword(s):  
Growth Performance ◽  
Candida Utilis ◽  
Average Daily Gain ◽  
Intestinal Flora ◽  
Animal Husbandry ◽  
Good Effect ◽  
Control Group ◽  
Intestinal Health ◽  
Weaned Piglets ◽  
Cecal Microflora

Abstract BackgroundEconomic benefit is an important goal pursued by animal husbandry industry. The emergence of antibiotics has promoted the development of animal husbandry, but many problems caused by the abuse of antibiotics have caused concerns about the use of antibiotics from all walks of life. Therefore, it is imperative to find alternatives to antibiotics. A large number of studies have shown that plant extracts and probiotics have certain potential in improving animal growth performance, antioxidant capacity and immune function. The purpose of this study was to explore the effects of Yucca Shidigera Extract (YSE) and Candida Utilis (CU) on weaned piglets. We compared and evaluated the effects of YSE and CU on weaned piglets from the aspects of growth performance, immunity, antioxidant function, ileal morphology and microflora changes. Forty 28-day-old healthy weaned piglets (Rongchang pig×Landrace×Large white) were randomly divided into 4 treatments: (1) control group (CON); (2) CU; (3) YSE; (4) CU+YSE. ResultsOur results showed that YSE and CU improved the growth performance by significantly increasing final weight, average daily gain (ADG) (P < 0.05), and there is decreasing trend of feed/gain ratio (P=0.087). The effect of adding YSE or CU alone on growth performance had little difference, and the effect of oral CU was slightly better than that of adding YSE. At the same time, the combination of YSE and CU had a good effect on reducing the diarrhea rate. In addition, both YSE and CU increased the diversity of cecal microflora, and CU increased the diversity more significantly, but did not change the dominant microflora of cecum. We also found that the addition of YSE and CU could maintain the structural integrity of intestinal tissue and regulate intestinal pH, to maintain the level of intestinal-associated immune proteins. At the same time, YSE and CU have certain benefits in regulating intestinal flora. ConclusionYSE and CU can improve the growth performance, reduce the diarrhea rate, improve intestinal health, and increase the diversity and abundance of cecal microflora in weaned piglets. Therefore, they are expected to be used as probiotics in the production of weaned piglets.

scholarly journals The Effects of the antimicrobial peptide WK3 on diarrhea, growth performance and intestinal health of weaned piglets challenged with enterotoxigenic Escherichia coli K88

2021 ◽  
Author(s):  
Licong Zhang ◽  
Tao Guo ◽  
Na Zhan ◽  
Taotao Sun ◽  
Anshan Shan
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Peptide ◽  
Growth Performance ◽  
Enterotoxigenic Escherichia Coli ◽  
Feed Additive ◽  
Control Group ◽  
Jejunal Mucosa ◽  
Intestinal Health ◽  
Villus Height ◽  
Crypt Depth

Background: Antibiotics are very effective for treating diarrhea in weaned pigs, but the global prohibition of antibiotics makes it urgent to find an alternative to antibiotics. Objective: An experiment was conducted to determine the antimicrobial activity of a linear trpzip-like β-hairpin antimicrobial peptide WK3 in vivo and to assess its effects on growth performance and intestinal health. Design: Thirty-two piglets were weaned at 21 days and housed in individual metabolic cages, which were randomly divided into four groups and were maintained on a corn-soybean meal-based basal diet. Group 1 included a blank group. Groups 2, 3, and 4 were orally infected by feeding with Enterotoxigenic Escherichia coli (ETEC) K88, which was followed by saline treatment (group 2), enrofloxacin injection at a dose of 2.5 mg/ kg (group 3), and WK3 injection at a dose of 2 mg/kg (group 4). The experiment lasted for 6 days, and feed and water were provided ad libitum. Results: Both WK3 and enrofloxacin effectively attenuated diarrhea and improved growth performance of piglets. Compared with the control group, WK3 significantly improved the villus height in the ileum (P < 0.05) but did not affect the villus height in the duodenum or jejunum. Additionally, we did not observe any obvious difference in crypt depth or villus height/crypt depth among the duodenum, jejunum and ileum (P > 0.05). WK3 also reduced the numbers of Enterococcus spp (P < 0.01) in the cecal contents, and the number of Enterobacterium spp tended to decrease (0.05 < P < 0.1). Moreover, the jejunal mucosa of the WK3 group exhibited lower interleukin-1α (IL-1a; P < 0.01), toll-like receptors-4 (TLR-4; P < 0.05), and myeloid differentiation primary response 88 (MyD88; P < 0.01) messenger ribonucleic acid (mRNA) expression levels. The jejunum of the WK3 group also exhibited an increased antioxidant capacity, reduced concentration of malondialdehyde (MDA; P < 0.05), and enhanced superoxide dismutase (SOD) activity (P < 0.05). Conclusions: WK3 has the potential to replace antibiotics as a new generation feed additive.

scholarly journals Effects of Diet Supplemented with Excess Pyrroloquinoline Quinone Disodium on Growth Performance, Blood Parameters and Redox Status in Weaned Pigs

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 359
Author(s):  
Dongxu Ming ◽  
Caiyun Huang ◽  
Wenhui Wang ◽  
Zijie Wang ◽  
Chenyu Shi ◽  
...  
Keyword(s):  
Serum Concentration ◽  
Growth Performance ◽  
Average Daily Gain ◽  
Pyrroloquinoline Quinone ◽  
Control Group ◽  
Growth Promoter ◽  
Feed Conversion ◽  
Weaned Pigs ◽  
Large White ◽  
Diarrhea Incidence

The research was implemented to assess the safety of feeding excess of pyrroloquinoline quinone disodium (PQQ·Na2) to 108 Duroc × Landrace × Large White weaned pigs (BW = 8.38 ± 0.47 kg). Pigs were weaned at 28 d and randomly distributed to one of three diets with six replicates and six pigs per replicate (three males and three females). Pigs in the control group were fed a corn-soybean meal-based diet (without growth promoter) while the two experimental diets were supplied with 7.5 and 75.0 mg/kg PQQ·Na2, respectively. Average daily gain (ADG), average daily feed intake (ADFI), feed conversion (F:G), diarrhea incidence, hematology, serum biochemistry, organ index and general health were determined. Diets supplementation with 7.5 mg/kg PQQ·Na2 in weaned pigs could increase ADG during the entire experimental period (p < 0.05). And there was a tendency to decrease F:G (p = 0.063). The F:G of weaned pigs fed 7.5 and 75.0 mg/kg PQQ·Na2 supplemented diets was decreased by 9.83% and 8.67%, respectively, compared to the control group. Moreover, pigs had reduced diarrhea incidence (p < 0.01) when supplemented with PQQ·Na2. No differences were observed between pigs supplemented with 0.0, 7.5 and 75.0 mg/kg PQQ·Na2 diets on hematological and serum biochemical parameters as well as histological assessment of heart, liver, spleen, lung and kidney. At day 14, pigs had increased activity of glutathione peroxidase (GSH-Px) (p < 0.05), catalase (CAT) (p < 0.05) and total antioxidant capacity (T-AOC) (p < 0.05), and the serum concentration of malondialdehyde (MDA) was decreased (p < 0.01) with PQQ·Na2 supplementation. At day 28, pigs had increased activities of total superoxide dismutase (T-SOD) (p < 0.01), GSH-Px (p < 0.01), CAT (p < 0.05) and T-AOC (p < 0.01), and serum concentration of MDA was lower (p < 0.01) with PQQ·Na2 supplementation. In conclusion, PQQ·Na2 can improve weaned pigs growth performance and serum antioxidant status. Meanwhile high PQQ·Na2 inclusion of 75.0 mg/kg does not appear to result in harmful effects on growth performance of pigs.

scholarly journals Effects of Rocket Seed Oil, Wheat Germ Oil, and Their Mixture on Growth Performance, Feed Utilization, Digestibility, Redox Status, and Meat Fatty Acid Profile of Growing Rabbits

Agriculture ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 662
Author(s):  
Sabrin Abdelrahman Morshedy ◽  
Ahmed M. Abdelmodather ◽  
Mohamed M. Basyony ◽  
Soliman A. Zahran ◽  
Mohamed A. Hassan
Keyword(s):  
Immune Response ◽  
Fatty Acid ◽  
Growth Performance ◽  
Wheat Germ ◽  
Seed Oil ◽  
Average Daily Gain ◽  
Feed Utilization ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Wheat Germ Oil

Vegetable oils are a source of natural antioxidants, including tocopherols, sterols, phenolic compounds, coenzymes, and polyunsaturated fatty acids that provide nutritional value, organoleptic properties, and significantly delay or prevent lipid oxidation. Eighty-four V-line rabbits at 5 weeks of age with an initial body weight (BW) of 535.60 ± 13.48 g were assigned randomly to four experimental groups (seven replicates in each group with three rabbits each). The first group served as a control and received 0.3 mL/kg BW of distilled water (CON), while the second and third groups received 0.3 mL/kg BW of rocket seed oil (RSO) and wheat germ oil (WGO), respectively. The fourth group received a mixture of oils consisting of 0.15 mL of RSO and 0.15 mL of WGO/kg BW (MOs). The experiment lasted 7 weeks. The study investigated the effects of RSO, WGO, and their mixture on growth performance, feed utilization, antioxidant status, and immune response of growing rabbits. The results indicated that the rabbits that were administered orally with RSO and WGO or their mixture had higher (p ≤ 0.05) final BW, weight gain, and average daily gain when compared to the control group. In addition, the feed conversion ratio improved significantly with RSO, WGO, and MOs treatments. Different oil treatments improved nutrient digestibility, nutritive value, and nitrogen balance. Moreover, the rabbits that received RSO, WGO, and their mixture had an improvement the meat fatty acid composition compared to the control rabbits. Oral administration of RSO, WGO, and their mixture significantly improved serum protein fractions, decreased blood urea nitrogen, and had a positive effect on serum total lipids, HDL-c, and LDL-c. Furthermore, the treatments of RSO, WGO, and MOs had a significant improvement in the antioxidative status and immune response.

scholarly journals Effects of Dietary Supplementation of gEGF on the Growth Performance and Immunity of Broilers

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1394
Author(s):  
Jianyong Zhou ◽  
Jingyi Yao ◽  
Luhong Bai ◽  
Chuansong Sun ◽  
Jianjun Lu
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Crude Extract ◽  
Serum Alkaline Phosphatase ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Control Group ◽  
Serum Samples ◽  
Chicken Embryos ◽  
Growth Of Animals

EGF has been shown to stimulate the growth of animals. In this study, the content of EGF in chicken embryos (gallus EGF, gEGF) aged from 1 to 20 days of incubation were determined by ELISA kit, and the 5-day-old chicken embryos with the highest content of 5593 pg/g were selected to make gEGF crude extracts. A total of 1500 1-day-old Xianju chickens were randomly divided into five groups with six replicates of 50 chickens each. The control group was fed a basal diet, and other treatment diets were supplemented with 4, 8, 16 and 32 ng/kg gEGF crude extract, respectively. The experiment lasted for 30 days. Chicks were harvested at the end of the experiment, and liver, spleen, thymus, bursa and serum samples were collected. Results showed that average daily gain (ADG) and average daily feed intake (ADFI) of 16 ng/kg group were higher than those in the control group (p < 0.05). The serum uric acid (UA) of the 16 ng/kg group was reduced (p < 0.01), and the serum alkaline phosphatase (AKP) of the 16 ng/kg group increased (p < 0.01). The gEGF extract also increased chick’s antioxidant capacity, decreased malondialdehyde (MDA) and increased catalase (CAT) in the liver and serum of 16 ng/kg groups in compared to the control group (p < 0.01). Furthermore, immunity was improved by the addition of gEGF to broiler diets. The serum immunoglobin A (IgA) content of 8 and 16 ng/kg groups and the serum immunoglobin M (IgM) content of 4 and 8 ng/kg groups were increased (p < 0.05) compared to the control group. The bursa index of each experimental group was higher than the control group (p < 0.01). These findings demonstrate that the crude extract of gEGF prepared in this experiment could improve the growth performance, antioxidant capacity and immunity of broilers.

PSVI-14 Blend of Additives in Nursery Pig Diets as an Antibiotics Substitute Increases the Growth Performance and Intestinal Health

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 201-201
Author(s):  
Sudario Roberto Silva Junior ◽  
Rhuan F Chaves ◽  
Maíra Resende ◽  
Ygor Henrique De Paula ◽  
Kenio De Gouvêa Cabral ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Feed ◽  
Block Design ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Intestinal Health ◽  
Total Period ◽  
Nursery Pigs ◽  
Randomized Block Design ◽  
Diarrhea Incidence

Abstract Antibiotics growth promoting (AGP) in animal feed has been restricted. With this, several additives have been tested in order to replace AGP and ensure intestinal health. The objective of this study was to evaluate the effects of a blend of additives on growth performance, diarrhea incidence and cecal content microbiota of nursery pigs. A total of 576 weaned pigs (6.21 ± 1.16 kg) were assigned into 4 treatments (12 replicates) in randomized block design: basal diet without additives (NC); basal diet with 120 ppm of halquinol (PC); NC + 0,05% blend of lactic acid (3,5%), benzoic acid (2,5%), flavonoids (3,5%) (B5); NC+ 0,1% of same blend (B10). The pigs were weighed 0 and 42 days into the experiment. On day 10, one animal per pen (10 replicates) was euthanized for microbiota analyses. The diarrhea incidence was calculated by the percentage of visual pens with diarrhea, by day, in the period. The growth performance was analyzed by GLIMMIX procedure and the means were compared with Tukey test (P &lt; 0.050) (SAS, 2009). Diarrhea incidence was analyzed by GENMOD procedure (SAS, 2009). The Kruskal Wallis test was used to compare microbial biodiversity (P &lt; 0.050) by statistical program STAMP. The final weight (P = 0.010) and average daily gain (P = 0.001) of B10 and PC were higher than NC. Regarding diarrhea, it was observed that the B5 and B10 had lower incidence when compared to other groups in the total period. In the microbiome analyses, it was observed that the B5, B10, and PC groups had lower (P = 0.021) biodiversity when compared to the NC piglets. However, the B5 and B10 group had higher biodiversity when compared to the PC group. In conclusion, the supplementation with 0,1% blend of additives can be a substitute for AGP.

Combined administration of bacteriocin- -producing, probiotic strain Enterococcus faecium CCM7420 with Eleutherococcus senticosus and their effect in rabbits

2013 ◽  
Vol 16 (4) ◽  
pp. 619-627 ◽  
Author(s):  
M. Pogány Simonová ◽  
A. Lauková ◽  
L. Chrastinová ◽  
I. Plachá ◽  
V. Strompfová ◽  
...  
Keyword(s):  
Growth Performance ◽  
Enterococcus Faecium ◽  
Average Daily Gain ◽  
Probiotic Strain ◽  
Cholesterol Concentration ◽  
Control Group ◽  
Feed Conversion ◽  
Eleutherococcus Senticosus ◽  
Commercial Diet ◽  
And Control

Abstract The effect of Enterococcus faecium CCM7420 (EF) - enterocin-producing and probiotic strain of rabbit origin, Eleutherococcus senticosus extract (ES) and their combination (ES+EF) was determined on selected bacteria in faeces and caecum content, leukocytes phagocytosis, blood biochemistry and growth performance. Ninety-six weaned rabbits were divided into 3 experimental (ES, EF, ES+EF) and control group (CG). The rabbits in the groups ES and EF+ES were fed commercial diet enriched with E. senticosus extract (30 g/100 kg feed), rabbits in groups EF and CG were fed untreated diet. The rabbits in the EF and ES+EF groups were administered with an overnight culture of E. faecium CCM7420 strain (500 μl/animal/day into water, 109 CFU/ml). The treatment period lasted 21 days. The microbiological examinations in faecal samples confirmed the presence of E. faecium CCM7420 strain. In groups EF and ES+EF, the reduction of faecal coliforms, Pseudomonas-like sp., Clostridium-like sp. and S. aureus was recorded. Leucocyte phagocytosis significantly increased in all experimental groups (P<0.0001) compared to CG. The lowest GPx values were measured in the ES+EF group. Higher total protein, triglycerides and calcium concentrations were detected in experimental groups compared to CG. The cholesterol concentration decreased in the ES group. The highest average daily gain was recorded in EF group; in ES+EF the better feed conversion ratio and no mortality was recorded. These results indicated that the dietary supplementation with the E. faecium CCM7420 and E. senticosus extract stimulate the leukocytes phagocytosis and reduces the potential pathogens in rabbits digestive tract without oxidative stress and improve the growth performance.

scholarly journals Dietary Enteromorpha Polysaccharide Enhances Intestinal Immune Response, Integrity, and Caecal Microbial Activity of Broiler Chickens

2021 ◽  
Vol 8 ◽  
Author(s):  
Teketay Wassie ◽  
Zhuang Lu ◽  
Xinyi Duan ◽  
Chunyan Xie ◽  
Kefyalew Gebeyew ◽  
...  
Keyword(s):  
Immune Response ◽  
Gut Microbiota ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Marine Algae ◽  
Basal Diet ◽  
Control Group ◽  
Villus Height ◽  
Crypt Depth ◽  
Caecal Microbiota

Marine algae polysaccharides have been shown to regulate various biological activities, such as immune modulation, antioxidant, antidiabetic, and hypolipidemic. However, litter is known about the interaction of these polysaccharides with the gut microbiota. This study aimed to evaluate the effects of marine algae Enteromorpha (Ulva) prolifera polysaccharide (EP) supplementation on growth performance, immune response, and caecal microbiota of broiler chickens. A total of 200 1-day-old Ross-308 broiler chickens were randomly divided into two treatment groups with ten replications of ten chickens in each replication. The dietary treatments consisted of the control group (fed basal diet), and EP group (received diet supplemented with 400 mg EP/kg diet). Results showed that chickens fed EP exhibited significantly higher (P &lt; 0.05) body weight and average daily gain than the chicken-fed basal diet. In addition, significantly longer villus height, shorter crypt depth, and higher villus height to crypt depth ratio were observed in the jejunal and ileal tissues of chickens fed EP. EP supplementation upregulated the mRNA expression of NF-κB, TLR4, MyD88, IL-2, IFN-α, and IL-1β in the ileal and jejunal tissues (P &lt; 0.05). Besides, we observed significantly higher (P &lt; 0.05) short-chain volatile fatty acids (SCFAs) levels in the caecal contents of the EP group than in the control group. Furthermore, 16S-rRNA analysis revealed that EP supplementation altered gut microbiota and caused an abundance shift at the phylum and genus level in broiler chicken. Interestingly, we observed an association between microbiota and SCFAs production. Overall, this study demonstrated that supplementation of diet with EP promotes growth performance, improves intestinal immune response and integrity, and modulates the caecal microbiota of broiler chickens. This study highlighted the application of marine algae polysaccharides as an antibiotic alternative for chickens. Furthermore, it provides insight to develop marine algae polysaccharide-based functional food and therapeutic agent.

Application of the feed additive «Abiotonic» in poultry farming

2021 ◽  
Vol 1 (10) ◽  
pp. 72-78
Author(s):  
Valentina M. Bachinskaya ◽  
◽  
Aleksandr A. Deltsov ◽  
Dmitrii V. Gonchar ◽  
◽  
...  
Keyword(s):  
Amino Acids ◽  
Egg Production ◽  
Laying Hens ◽  
Average Daily Gain ◽  
Live Weight ◽  
Poultry Meat ◽  
Feed Additive ◽  
Control Group ◽  
Standard Diet ◽  
Nonessential Amino Acids

This paper presents a study of the effect of the feed additive «Abiotonic» on the indicators of egg and meat productivity when applied to laying hens. It was found that with the additional introduction of this additive into the standard diet of poultry, the content of nonessential amino acids in their meat is 10% higher compared to the same parameters in the meat of chickens of the control group, the content of partially nonessential amino acids is by 8,5%, and of irreplaceable amino acids is by 6,7%. In addition, in the meat of laying hens, which used the feed additive «Abiotonic», the content of selenium (Se) is 29,4% higher than in the meat of birds of the control group, and iron (Fe) – by 20%. The average daily gain in live weight of the birds in the experimental group was 3,6 g more than in the control hens. Microbiological research made it possible to establish that poultry meat, regardless of the introduction of the feed additive «Abiotonik», meets the established requirements and is safe for human consumption. «Abiotonic», in addition, significantly improves the egg production of birds. It was found that the weight of eggs with the introduction of this feed additive in the diet in addition to the compound feed increased by an average of 1,2 g, and the egg production increased by 23 eggs in 7 days.

EFFECT OF VARIOUS FORMS OF SELENIUM ON THE PRODUCTIVITY AND METABOLISM OF FATTENED YOUNG PIGS IN PRODUCTION CONDITIONS

2021 ◽  
pp. 55-65
Author(s):  
M.G. CHABAEV ◽  
◽  
E.YU. TSIS ◽  
R.V. NEKRASOV ◽  
M.I. KLEMENTEV
Keyword(s):  
Blood Cells ◽  
Average Daily Gain ◽  
White Blood Cells ◽  
Live Weight ◽  
Growing Pigs ◽  
Control Group ◽  
Protein Activity ◽  
Large White ◽  
Organic Selenium ◽  
Young Pigs

Selenium plays an important role for maintaining complex and adequate nutrition of fattened young pigs. It also has a big biological importance to maintain growth and health, as well as for biochemical and physiological processes This study presents the results of a production experiment to determine the effect of organic and inorganic forms of selenium on growth indicators, immunohematological blood parameters and slaughter qualities of fattened pigs in period I and II. Test feeding with various forms of selenium has been implemented with two groups of analogs (N = 60; n = 30), taking into account age and live weight. The experiment was conducted on castrates of large white breed, which were divided into two groups of 30 heads each following the principle of analogues (taking into account their age, live weight). The studied fattened pigs received standard complete feeds of the SK-5 and SK-6 types for a period of 105 days. Growing pigs were fed with organic selenium for 20 mg/kg as part of the feed 64 mixture per head in the first and second period of fattening, while the animals of the control group were fed with 0.3 mg/kg of the inorganic form of selenium. Including a chelated form of selenium in the complete feed of castrates at the rate established in the course of scientific and economic studies has led to 757 g of average daily gain, which is 8.1% more as compared to the control group. The concentration of red blood cells in the blood of growing pigs fed with 20 mg/kg of selenium chelate increased by 6.3%, hemoglobin – by 2.4%, and white blood cells – by 7.1% as compared to the control. Feeding organic selenium to fattened young pigs contributed to a significant increase in specific units of protein activity by 38.65% (p < 0.01), BASC – by 7.63%, as well as lysis – by 40.06% (p < 0.05), and phagocytic activity by 3.33% in blood serum as compared to the control. The half-carcasses of hogs who had received fed rations including selenium chelate fetured slaughter weight and slaughter yield, respectively, higher – by 6.4 and 0.6% as compared with the control analogues. The use of the established norm of organic selenium in the diets of fattened young pigs according to the results of production testing is economically profitable and contributes to a per-head profit of 420 rubles.

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