Alan Rabinowitz and the Jaguar

Hold On ◽  
2020 ◽  
pp. 29-56
Author(s):  
Peter Toohey
Keyword(s):  

What is it in a human brain that allows some individuals to like to wait when placed in a situation where most people, consumed by fear, would bolt? There are two brain chemicals that appear to enable an individual’s capacity to wait. Both seem to do this by “modulating” ort enabling the value of waiting for a reward to come. There are two great enablers of waiting, the neuromodulators dopamine and serotonin. In this chapter I’ll attempt to exemplify the operation of the neuromodulator serotonin in the life of the scientist, author, and big cat expert, Alan Rabinowitz. Fort the operation of dopamine, I’ll look at, amongst others, the famous sniper, Chris Kyle.

10.28945/3927 ◽  
2017 ◽  
Vol 6 ◽  
pp. 11
Author(s):  
Grandon Gill ◽  
Bernardo Rodrigues

A physicist who studies the human brain has adapted dynamic logic, a machine learning algorithm he developed, to run on a test database of network traffic. The algorithm has proven surprisingly adept at identifying malware traffic. Now he ponders how the project might move forward, given that cybersecurity is entirely outside of his domain of expertise (and interest). Dr. Leonid Perlovsky, distinguished physicist and cognitive scientist, pondered this question, which could have a significant impact on his research direction in the years to come. Over the past few decades, he had developed and refined algorithms for distinguishing objects in images, an approach that had found its way into various classified U.S. Department of Defense (DoD) applications. Now he was looking for new potential opportunities to see his research applied, allowing it to evolve further. One of the most interesting aspects of Perlovsky’s approach was that it was very similar to that taken by the human brain in processing sensory information. It began with a very vague model of what might or might not be present in the data being examined. Through successive iterations, analogous to the layers of processing used in human sensory systems, the patterns in the data corresponding to objects would grow more and more distinct until, finally, they became recognizable. Unlike most statistical techniques, this approach—termed “dynamic logic” by Perlovsky—did not require that a model be specified in advance. As such, it was well suited for contexts that required discovery. One application of dynamic logic that particularly impressed him involved the detection of malware in network packet data. Using an externally provided database of this traffic, his algorithm had successfully identified the presence of malware with almost eerie precision, and with substantially less processing than competing techniques. This suggested that dynamic logic could well become a powerful tool in the arsenal of IT professionals seeking to protect their systems from hackers. What other possible cybersecurity-related opportunities might be well suited to this tool? Identifying potential opportunities represented only part of the challenge of putting dynamic logic to work. After letting the project lay dormant for several years, he had recently been approached by an energetic Brazilian master’s student who had identified ways that DL (dynamic logic) could be used. The student had also established a DL open source project on his own initiative. If that project were to move forward, Perlovsky would need to provide some encouragement and guidance. But he had his own set of questions. Was the open source path the right way to proceed? What potential application should be given highest priority? Should government or commercial funding be pursued? And the big question… Perlovsky readily acknowledged that he was no cybersecurity expert. Given that he was already actively pursuing grants from the DoD and National Institute of Health (NIH), would it really make sense to split his attention further, and look towards tackling an entirely new class of problems?


Author(s):  
J. Anthony VanDuzer

SummaryRecently, there has been a proliferation of international agreements imposing minimum standards on states in respect of their treatment of foreign investors and allowing investors to initiate dispute settlement proceedings where a state violates these standards. Of greatest significance to Canada is Chapter 11 of the North American Free Trade Agreement, which provides both standards for state behaviour and the right to initiate binding arbitration. Since 1996, four cases have been brought under Chapter 11. This note describes the Chapter 11 process and suggests some of the issues that may arise as it is increasingly resorted to by investors.


2016 ◽  
Vol 39 ◽  
Author(s):  
Giosuè Baggio ◽  
Carmelo M. Vicario

AbstractWe agree with Christiansen & Chater (C&C) that language processing and acquisition are tightly constrained by the limits of sensory and memory systems. However, the human brain supports a range of cognitive functions that mitigate the effects of information processing bottlenecks. The language system is partly organised around these moderating factors, not just around restrictions on storage and computation.


Author(s):  
P. A. Madden ◽  
W. R. Anderson

The intestinal roundworm of swine is pinkish in color and about the diameter of a lead pencil. Adult worms, taken from parasitized swine, frequently were observed with macroscopic lesions on their cuticule. Those possessing such lesions were rinsed in distilled water, and cylindrical segments of the affected areas were removed. Some of the segments were fixed in buffered formalin before freeze-drying; others were freeze-dried immediately. Initially, specimens were quenched in liquid freon followed by immersion in liquid nitrogen. They were then placed in ampuoles in a freezer at −45C and sublimated by vacuum until dry. After the specimens appeared dry, the freezer was allowed to come to room temperature slowly while the vacuum was maintained. The dried specimens were attached to metal pegs with conductive silver paint and placed in a vacuum evaporator on a rotating tilting stage. They were then coated by evaporating an alloy of 20% palladium and 80% gold to a thickness of approximately 300 A°. The specimens were examined by secondary electron emmission in a scanning electron microscope.


Author(s):  
K.S. Kosik ◽  
L.K. Duffy ◽  
S. Bakalis ◽  
C. Abraham ◽  
D.J. Selkoe

The major structural lesions of the human brain during aging and in Alzheimer disease (AD) are the neurofibrillary tangles (NFT) and the senile (neuritic) plaque. Although these fibrous alterations have been recognized by light microscopists for almost a century, detailed biochemical and morphological analysis of the lesions has been undertaken only recently. Because the intraneuronal deposits in the NFT and the plaque neurites and the extraneuronal amyloid cores of the plaques have a filamentous ultrastructure, the neuronal cytoskeleton has played a prominent role in most pathogenetic hypotheses.The approach of our laboratory toward elucidating the origin of plaques and tangles in AD has been two-fold: the use of analytical protein chemistry to purify and then characterize the pathological fibers comprising the tangles and plaques, and the use of certain monoclonal antibodies to neuronal cytoskeletal proteins that, despite high specificity, cross-react with NFT and thus implicate epitopes of these proteins as constituents of the tangles.


Author(s):  
C.K. Hou ◽  
C.T. Hu ◽  
Sanboh Lee

The fully processed low-carbon electrical steels are generally fabricated through vacuum degassing to reduce the carbon level and to avoid the need for any further decarburization annealing treatment. This investigation was conducted on eighteen heats of such steels with aluminum content ranging from 0.001% to 0.011% which was believed to come from the addition of ferroalloys.The sizes of all the observed grains are less than 24 μm, and gradually decrease as the content of aluminum is increased from 0.001% to 0.007%. For steels with residual aluminum greater than 0. 007%, the average grain size becomes constant and is about 8.8 μm as shown in Fig. 1. When the aluminum is increased, the observed grains are changed from the uniformly coarse and equiaxial shape to the fine size in the region near surfaces and the elongated shape in the central region. SEM and EDAX analysis of large spherical inclusions in the matrix indicate that silicate is the majority compound when the aluminum propotion is less than 0.003%, then the content of aluminum in compound inclusion increases with that in steel.


Author(s):  
C. S. Potter ◽  
C. D. Gregory ◽  
H. D. Morris ◽  
Z.-P. Liang ◽  
P. C. Lauterbur

Over the past few years, several laboratories have demonstrated that changes in local neuronal activity associated with human brain function can be detected by magnetic resonance imaging and spectroscopy. Using these methods, the effects of sensory and motor stimulation have been observed and cognitive studies have begun. These new methods promise to make possible even more rapid and extensive studies of brain organization and responses than those now in use, such as positron emission tomography.Human brain studies are enormously complex. Signal changes on the order of a few percent must be detected against the background of the complex 3D anatomy of the human brain. Today, most functional MR experiments are performed using several 2D slice images acquired at each time step or stimulation condition of the experimental protocol. It is generally believed that true 3D experiments must be performed for many cognitive experiments. To provide adequate resolution, this requires that data must be acquired faster and/or more efficiently to support 3D functional analysis.


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