scholarly journals Association Between Self-Reported Spinal Morning Stiffness and Radiographic Evidence of Lumbar Disk Degeneration in Participants of the Cohort Hip and Cohort Knee (CHECK) Study

2019 ◽  
Vol 100 (2) ◽  
pp. 255-267 ◽  
Author(s):  
Roxanne van den Berg ◽  
Elisabeth M Jongbloed ◽  
Natalia O Kuchuk ◽  
Bart W Koes ◽  
Edwin H G Oei ◽  
...  
Keyword(s):  
Morning Stiffness ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Radiographic Evidence ◽  
Cross Sectional ◽  
Disk Space ◽  
Lumbar Disk ◽  
Disk Degeneration ◽  
Lumbar Disk Degeneration ◽  
Disk Space Narrowing

Abstract Background Low back pain (LBP) is very common and is a main cause of limited activity and work absence. Patients with LBP may also report spinal morning stiffness; this symptom could be useful for identifying subgroups with signs and symptoms related to spinal osteoarthritis. Objective This study investigated whether an association exists between reported spinal morning stiffness and radiographic evidence of lumbar disk degeneration (LDD) in people with LBP and a history of pain of the hip and/or knee. Design This cross-sectional study used 8-year follow-up data from the Cohort Hip and Cohort Knee study. Methods The association between spinal morning stiffness and radiographic LDD features was assessed with multivariable logistic regression models. Results The presence of osteophytes was significantly associated with spinal morning stiffness (odds ratio [OR] = 2.1 [95% confidence interval [CI] = 1.3–3.2]) as was the presence of grade 2 or 3 disk space narrowing (OR = 2.0 [95% CI = 1.1–3.5]). There was also a significant association between morning stiffness persisting for > 30 minutes and grade 2 osteophytes (OR = 2.6 [95% CI = 1.1–6.2]) and grade 1 disk space narrowing (OR = 2.0 [95% CI = 1.1–3.6]). Furthermore, there was a significant association between moderate spinal morning stiffness and the presence of osteophytes (OR = 2.0 [95% CI = 1.2–3.2]). Both the presence of osteophytes and disk space narrowing were significantly associated with severe spinal morning stiffness (for osteophytes: OR = 2.0 [95% CI = 1.2–3.7]; for narrowing at L1-S1: OR = 1.8 [95% CI = 1.1–3.1]). Limitations Only lumbar lateral radiographs were available for each participant, implying that the LDD features could have been underestimated. The quality of the radiographs was not consistent. Conclusions This study showed an association between self-reported spinal morning stiffness and symptomatic LDD. When morning stiffness lasted > 30 minutes, there was a significant association with the features of LDD. The association was stronger when the severity of spinal morning stiffness increased.

RELATIONSHIP BETWEEN DISABILITY AND RADIOGRAPHIC FINDINGS OF LUMBAR DISK DEGENERATION IN SAMPLE OF IRAQI PATIENTS WITH MECHANICAL LOW BACKACHE

2021 ◽  
pp. 83-88
Author(s):  
KHUDAIR AL-BEDRI ◽  
RIYAM ALI ◽  
ZAINAB A. MAHMOOD
Keyword(s):  
Back Pain ◽  
X Rays ◽  
Radiographic Findings ◽  
X Ray ◽  
Disk Space ◽  
Lumbar Disk ◽  
Disk Degeneration ◽  
Lumbar Disk Degeneration ◽  
Severity Of Disability ◽  
Disk Space Narrowing

Objectives: Disability related to chronic low back pain (LBP) is a complex and multidimensional phenomenon all over the world. The prevalence of backache in middle age and elderly is up to 84%. This study aims to evaluate the associations of X-ray features of lumbar disk degeneration with severity of disability among patients with mechanical LBP. Patients and Methods: A cross-sectional study was conducted on a total of 300 patients with chronic mechanical LBP. Severity of disability was measured using Modified Oswestry Disability Index and intensity of backache was assessed using numeric rating scale (0–10). X-ray features of lumbar disc degeneration according to Lane classification and spondylolisthesis were assessed in lateral recumbent lumbar X-rays. Results: The mean age of our sample was 52.45±7.87 and 71.7% of involved patients were women. Most patients were recorded as overweight or obese. The findings of disk space narrowing were mild in 65.7%, moderate in 28.7%, and severe in 5.6%, where the presence of osteophytes were small in 76.9%, moderate in 20.5%, and large in 2.6%. Regarding disability, two-third of cases were focused on minimal disability, followed by moderate, severe, and crippled as (26%), (6%), and (2%), respectively. There was highly significant association between women and pain radiation to legs (p=0.004). Obesity and overweight had meaningless effects on all markers. Conclusions: The severity of disability was significantly more in women, high intensity of lower back pain, presence of pain radiating to legs, moderate/severe disk space narrowing on X-ray, and disk degenerative disease score on X-ray, while age, presence of osteophytes and spondylolisthesis, body mass index, and pain duration were not associated with severity of disability.

scholarly journals Genetic variants in COL11A2 of lumbar disk degeneration among Chinese Han population

2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Xuejun Yang ◽  
Haiyu Jia ◽  
Wenhua Xing ◽  
Feng Li ◽  
Manglai Li ◽  
...  
Keyword(s):  
Genetic Variants ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Han Population ◽  
Lumbar Disk ◽  
Disk Degeneration ◽  
Lumbar Disk Degeneration

scholarly journals Signs and symptoms in Gaucher Disease: priority nursing diagnoses

2018 ◽  
Vol 71 (1) ◽  
pp. 104-110 ◽  
Author(s):  
Márcia Koja Breigeiron ◽  
Vitória da Costa Moraes ◽  
Janice Carneiro Coelho
Keyword(s):  
Gaucher Disease ◽  
Bone Pain ◽  
Genetic Diagnosis ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Physical Mobility ◽  
Risk For Bleeding ◽  
Nursing Diagnoses

ABSTRACT Objective: Identify the signs and symptoms of patients with Gaucher Disease, inferring possible priority nursing diagnoses. Method: Cross-sectional study, developed in a specialized laboratory, between 2013 and 2015. The sample (n = 91) comprised the records of patients with genetic diagnosis for Gaucher Disease. The study respected research norms. Results: Prevalence of female sex (57.1%), age at diagnosis between 0 and 10 years, and origin from the Southeast Region of Brazil were prevalent. Hematologic changes, bone pain, hepatomegaly, splenomegaly, and fatigue were the most recurrent signs and symptoms. The inferred diagnoses for the studied population were: Risk for bleeding; Fatigue; Chronic pain and Acute pain; Impaired physical mobility; Imbalanced nutrition: less than body requirements; and Risk for Developmental Delay. Conclusion: The establishment of Priority Nursing Diagnoses based on signs and symptoms makes it possible to achieve expected outcomes for each individual in the care context.

scholarly journals Pain in emergency units: correlation with risk classification categories

2018 ◽  
Vol 26 (0) ◽  
Author(s):  
Wandressa Letícia Viveiros ◽  
Meiry Fernanda Pinto Okuno ◽  
Cássia Regina Vancini Campanharo ◽  
Maria Carolina Barbosa Teixeira Lopes ◽  
Gabriella Novelli Oliveira ◽  
...  
Keyword(s):  
Signs And Symptoms ◽  
Medical Specialty ◽  
Cross Sectional Study ◽  
Risk Classification ◽  
Moderate Intensity ◽  
Ratio Test ◽  
Intense Pain ◽  
Cross Sectional ◽  
Mild Pain

ABSTRACT Objectives: to correlate risk classification categories with the level of pain of patients in an emergency service. Method: cross-sectional study carried out in the Risk Classification of 611 patients. The variables studied were: age, gender, comorbidities, complaint duration, medical specialty, signs and symptoms, outcome, color attributed in the risk classification of and degree of pain. We used Analysis of Variance, a Chi-Square test and a Likelihood Ratio test. Results: the average age was 42.1 years (17.8); 59.9% were women; the green (58.9%) and yellow (22.7%) risk classification prevailed and hypertension (18.3%) was the most common Comorbidity. The most frequent pain intensity was moderate (25.9%). In the red category, patients presented a higher percentage of absence of pain; in the blue, mild pain; and in the green, yellow and orange categories, there was a greater percentage of intense pain (p < 0.0001). Conclusion: among the patients who presented pain, the majority reported moderate intensity. Regarding risk categories, most patients in the red category did not report pain. Those who were classified as green, yellow and orange, reported mostly intense pain. On the other hand, patients in the blue category reported predominantly mild pain.

scholarly journals Mental health and burden in mothers of children with congenital Zika syndrome during COVID-19 pandemic

2021 ◽  
Vol 21 (suppl 2) ◽  
pp. 481-490
Author(s):  
Gabriela Lopes Gama ◽  
Bruna Milena da Silva ◽  
Mariana Balbino da Silva ◽  
Rayssa Vieira Brandão Ferreira ◽  
Jousilene de Sales Tavares ◽  
...  
Keyword(s):  
Mental Health ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Symptoms Of Depression ◽  
Maternal Schooling ◽  
The Social ◽  
Burden Scale ◽  
Congenital Zika Syndrome ◽  
Health Impairments

Abstract Objectives: to evaluate burden, frequency of anxiety and signs and symptoms of depression in mothers of children with congenital Zika syndrome (CZS) during the COVID-19 pandemic and the social isolation period. Methods: this is a cross-sectional study conducted with mothers who care for their children with CZS. The data were collected by an online form with questions regarding mother's socioeconomic conditions and questions related with Zarit burden scale and Beck's inventories on depression and anxiety. Spearman’s correlation tests and multiple regression analyzes were performed to assess factors related to mothers' burden and mental health. Results: 41 mothers were evaluated, 51.2% had mild burden, 39% had minimal anxiety and 73.2% did not have signs and symptoms of depression. Negative correlations were observed between levels of burden and maternal schooling (p=0.01), presence of signs and symptoms of anxiety and receiving financial aid (p<0.04) as well as the presence of signs and symptoms of anxiety and having children with seizures history (p=0.03). Conclusion: despite the risk of their children again being victims of an epidemic virus, mothers who care for their children with CZS did not present serious mental health impairments.

scholarly journals Insomnia among medical students: a cross-sectional study

2019 ◽  
Vol 7 (3) ◽  
pp. 893
Author(s):  
Hassan Abdullah Shakeel ◽  
Hamza Maqsood ◽  
Asher Ishaq ◽  
Basit Ali ◽  
Humza Hussain ◽  
...  
Keyword(s):  
Medical Students ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Poor Quality ◽  
Cross Sectional ◽  
Athens Insomnia Scale ◽  
Falling Asleep ◽  
Quality Sleep ◽  
Waking Up ◽  
Socio Demographic Factors

Background: Insomnia, the most common sleep disorder, is the perception or complaint of inadequate or poor-quality sleep because of one or more of the following conditions: difficulty in falling asleep, frequent waking up during the night with difficulty for returning to sleep, waking up too early in the morning, or unrefreshing sleep. It is the most common sleep related complaint reported in the primary care setting. Medical students are specially at risk of developing insomnia and its consequences. This study evaluates the prevalence and severity of insomnia in medical students in relation to certain socio-demographic factors like age, sex and class of education.Methods: A questionnaire based study was done on 135 medical students of Nishtar Medical University, Multan chosen on basis of random sampling to test the prevalence of insomnia using Athens Insomnia Scale (AIS). Out of these students 75 were males and 60 were females. Students were interviewed to obtain information about age, sex and academic year of education.Results: According to Athens insomniac scale scoring, 55 (40.74%) students were found insomniac while 80 (59.25%) were non-insomniac. Out of 55 insomniac students, 23 (41.81%) were males while 32 (58.18%) were females. Likewise, out of 80 non-insomniac students, 52 (65%) were males while 28 (35%) were females. The prevalence of insomnia in medical students was found to be increased with the increasing age. It was found that the females have more insomnia prevalence as well as more severe signs and symptoms of insomnia. Moreover, final year students tend to show more prevalence and severity of insomnia than their juniors.Conclusions: According to this study, 2 out of every 5 students were insomniac. Demographic comparison showed that the prevalence and severity of insomnia was more in females and final year students. Also, it was increasing side by side with increasing age.

scholarly journals Incidência de Interações Medicamentosas e Avaliação Clínica nos Pacientes de um Hospital Público Brasileiro

2020 ◽  
Vol 24 (3) ◽  
pp. 202-210
Author(s):  
Fabiana Cristina Furquim ◽  
Cristina Eunice Okuyama ◽  
Sandro Rostelato-Ferreira ◽  
Carla Leticia Rivero-Wendt ◽  
Helder Oliveira ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Positive Association ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Documentary Evidence ◽  
Potential Ddis ◽  
Cross Sectional ◽  
De Se ◽  
Clinical Interactions

Interações droga-droga (IDDs) são responsáveis por problemas terapêuticos e as principais causas de reações adversas a medicamentos que levam a hospitalização. O objetivo do trabalho foi analisar a incidência de IDDs em pacientes admitidos em hospital público no Brasil, em 2015. Em um estudo transversal, 351pacientes foram selecionados com IDDs utilizando-se o banco de dados da Micromedex®, e as interações foram classificadas de acordo com a severidade e documentação. Os potenciais IDDs foram avaliados durante o acompanhamento farmacoterapêutico diário por anamnese farmacêutica e a análise dos exames laboratoriais foi realizada. Um total de 2.937 potenciais IDDs foram identificados e 28,42% deles tinham sinais e sintomas clínicos confirmados em 87 pacientes (29%). Entre os pacientes que apresentaram interações, 62,07% tinham mais que 60 anos. Neste grupo de idade, 61,27% de todos os sinais e sintomas clínicos observados foram também identificados, demonstrando uma associação positiva entre interações clínicas e idade. Além disso, uma correlação positiva entre o número de drogas prescritas e a ocorrência de sinais clínicos também foram observados. Muitos IDDs observados foram de severidade moderada e estavam relacionados a alterações das pressões arteriais e níveis glicêmicos. Este estudo demonstrou que IDDs estão diretamente relacionados a idade e número de drogas prescritas. E a grande frequência de IDDs com documentação fraca alertam para a necessidade de se analisar esse tipo de interação. Sendo assim, este estudo mostrou que potenciais IDDs e sinais e sintomas clínicos significantes em pacientes só reforçam a necessidade de se apoiar a farmácia clínica.   Palavras-chave: Interação Droga-Droga (IDD). Pacientes Internados. Farmacoterapia, Poli Farmácia. Sinais e Sintomas.   Abstract Drug-drug interactions (DDIs) are responsible for therapeutic problems and the main causes of adverse drug reactions that require hospitalization. The aim of this study was to analyze the incidence of DDIs in patients admitted in a Public Hospital in Brazil, in 2015. In a cross-sectional study, DDIs were screened in 351 patients, using Micromedex® database, that classify interactions according to severity and documentary evidence. Potential DDIs were assessed at the daily pharmacotherapeutic follow-up through pharmaceutical anamnesis and analysis of laboratory tests were performed. A total of 2,937 potential DDIs were identified and 28.42% of these had confirmed signs and symptoms clinical in 87 patients (29%). Among the patients that presented interactions, 62.07% were older than 60 years. In this age group, 61.27% of all signs and symptoms clinical observed in the study were also identified, demonstrating a positive association between the occurrence of clinical interactions and age. In addition, a positive correlation between the number of drugs prescribed and the occurrence of signs clinicals was also observed. Most DDIs observed were of moderate severity and were related to imbalance of blood pressure and glycemic levels. This study demonstrated that DDIs are directly related to the age and number of drugs prescribed. And the greater frequency of DDIs with fair documentary evidence alerts to the need to consider all the possible interactions. Thereafter, this study showed that potential DDIs and sign and clinical symptoms  are significant in patients and reinforce the need to support Clinical Pharmacy.   Keywords: Drug-Drug Interaction (DDI). Inpatients. Pharmacotherapy. Poly Pharmacy. Sign and Symptom.    

scholarly journals High Anti-HCV Seroprevalence and Low Performance of ICT Strip in Diagnosing Hepatitis C Virus Infection in Children in Enugu Metropolis

2018 ◽  
Vol 12 (1) ◽  
pp. 149-156
Author(s):  
Maryann C. Ezeilo ◽  
Godwill A. Engwa ◽  
Romanus I. Iroha ◽  
Damian N. Odimegwu
Keyword(s):  
Risk Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Test Performance ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Hcv Infection ◽  
Enzyme Linked Immunosorbent Assay ◽  
Cross Sectional

Background:The lack of a vaccine for Hepatitis C virus (HCV) places children at a high risk of contracting the infection. It becomes necessary to accurately diagnose this infection for proper treatment as well as identifying potential risk factors for effective management.Aim:This study was conceived to assess the test performance of the commonly used Immunochromatographic test (ICT) strip and identify the associated clinical manifestations and risk factors of HCV in children in Enugu Metropolis.Method:A cross-sectional study involving randomly selected 270 children below six years of age was conducted in Enugu Nigeria. The subjects were screened for anti-HCV by ICT and Enzyme-Linked Immunosorbent Assay (ELISA) and the demographic, signs and symptoms and risk factors were collected.Results:A total of 50 out of 270 children were positive for anti-HCV with a seropositivity of 18.5%. ICT strip had a very low sensitivity of 38.00% with an accuracy of 88.52% in detecting anti-HCV. The presence of dark urine was associated (p= 0.01) with HCV infection.Conclusion:A seroprevalence of 18.5% of Anti-HCV was found in children below six years old in Enugu metropolis and the performance of ICT in diagnosing HCV infection was poor compared to ELISA.

scholarly journals Awareness about breast feeding practices and vitamin A deficiency among mothers in Srikakulam district of Andhra Pradesh, South India

2021 ◽  
Vol 8 (5) ◽  
pp. 2346
Author(s):  
Vasantha Rao Sappati ◽  
Sannapaneni Krishnaiah ◽  
Suneetha Sapur
Keyword(s):  
Vitamin A ◽  
Breast Feeding ◽  
Andhra Pradesh ◽  
Vitamin A Deficiency ◽  
Sampling Strategy ◽  
Signs And Symptoms ◽  
Feeding Practices ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cross Sectional

Background: To assess the awareness about breast feeding practices and to assess the knowledge, attitude and practice about the signs and symptoms of vitamin A deficiency (VAD) and vitamin A rich foods intake among mothers of children below 5 years in the Srikakulam district of Andhra Pradesh (AP) in South India.Methods: A population based cross-sectional study was conducted on 284 mothers (age range 14 to 36 years) during June 2011 and September 2011. A combined simple and systematic random sampling strategy was used to select mothers from one tribal, rural and semi urban area with a representative sample of the Srikakulam district. A standardized structured questionnaire that was developed and validated by the National institute of nutrition, Hyderabad was utilized for this study.Results: The awareness of vitamin A and night blindness was 68.7% (95% confidence intervals (CI): 62.9–74.0) (n=195) and 93.7% (95% CI: 90.2–96.2) (n=266) respectively. The knowledge of signs and symptoms of vitamin A deficiency (VAD) was nil among illiterate mothers and low among literates; with primary education, adjusted odds ratio (OR): 0.01 (95% CI: 0.00, 0.06) and with secondary education, OR: 0.19 (95% CI: 0.06, 0.62) compared to mothers with graduation and above.Conclusions: There is a need to increase the awareness and knowledge about VAD among mothers with children below 5 years in the southern state of AP.

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