P037 Does perinatal history and delivery enhance the risk of hip involvement in Juvenile Idiopathic Arthritis patients? A case-control study

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
Makhlouf Yasmine ◽  
Hanene Ferjani ◽  
Affes Hassen ◽  
Kaouther Maatallah ◽  
Dorra Ben Nessib ◽  
...  

Abstract Background Children are vulnerable to congenital and developmental hip disorders. One of the causes of coxitis among children is juvenile idiopathic arthritis (JIA). Existing data on associations between maternal and early childhood exposures highlighted the potential role of prematurity in JIA [1]. The aim of this study was to compare perinatal history in JIA children with coxitis compared with patients with other causes of hip involvement. Methods We conducted a cross-sectional study including children with JIA complicated with coxitis and patients with other causes of hip involvement. We recorded sociodemographic data and the hip disorder. The mode of delivery, the values of the neonatal birth weight as well as the delivery method (vaginal, cesarean (C) section) were retrieved from medical records. We divided the patients into two groups: G1: JIA patients with coxitis and G2: patients with other causes of hip involvement. We compared delivery mode, as well as perinatal outcomes between the two groups. Results The study included 81 patients. There was a male predominance (59.3% males vs 40.7% females) with a sex-ratio of 1.45. The mean age of diagnosis was 9.9 years [1–16]. The mean disease duration was 9 months [0.1–156]. Hip disorders were distributed as follows: Legg-Calvé-Perthes disease (n = 3), epiphysiolysis of the femur head (n = 30), transient synovitis of the hip n = 7, septic hip (n = 10), tumor (n = 4), hip dislocation (n = 8), hip dysplasia (n = 4), juvenile idiopathic arthritis with coxitis (n = 15). The mean birth weight of the children was 3.4 kg [1.3–9]. About half of the patients had a natural delivery (55.6%) and most of them a face presentation (71.6%). A twin pregnancy was reported only in 2.5% of cases. Childbirth complications were reported in 7.4% of cases: umbilical cord prolapse (n = 1), Meconium aspiration syndrome (n = 1), failure to descend (n = 1), acute fetal distress (n = 3). Most of them had a normal growth and psychomotor development (96% and 97% respectively). There was no statistical difference between the two groups regarding delivery mode and fetal presentation before birth (P = 0.07, P = 0.48 respectively). Similarly, weight at birth was similar between JIA children and patients with other hip involvement (P = 0.52). Conclusion Our study showed that maternal and perinatal history did not differ between JIA patients with coxitis and patients with other causes of hip involvement.

2020 ◽  
Vol 5 (2) ◽  
pp. 24-27
Author(s):  
Leo Jumadi Simanjuntak ◽  
Patrick Anando Simanjuntak

Background: Estimated fetal weight (EFW) is important to determine mode of delivery. The use of estimated fetal weight based on fundal height has been widely used, but the use on overweight mothers is still limited. Objectives: This study aimed to compare the Johnson’s and Risanto’s formula in estimating fetal weight on overweight mothers. Method: The design used was cross-sectional, conducted at Mitra Sejati, Herna, and Methodist Sussana Wesley hospital on November 2019 until January 2020. Mann-Whitney test was used to compare EFW mean differences between Johnson’s and Risanto’s to actual birth weight. Paired t-test was used to compare EFW mean differences between Johnson’s and Risanto’s. Results: There were 103 overweight pregnant mothers fulfilling study criteria. The BMI mean was 31,26 ± 5l,54 kg/m2. Both Johnson’s and Risanto’s formula had no significant mean difference compare to actual birth weight, of 332,45 gram on Johnson’s (p value = 0,070) and 298,57 gram on Risanto’s (p value = 0,863). The mean difference between Risanto’s formula and actual birth weight was significantly lower than Johnson’s (mean difference = 33,88 gram, p value = 0,01). Conclusions: EFW measurement using Johnson’s and Risanto’s formula based on fundal height can be applied and used properly by health care workers. Risanto’s formula was more accurate to estimate fetal weight than Johnson’s in overweight mothers.   Latar belakang: Menentukan taksiran berat janin (TBJ) adalah penting bagi penolong persalinan untuk menentukan jenis persalinan. Pengukuran TBJ menggunakan tinggi fundus uterus merupakan metode yang banyak digunakan, namun penggunaan pada ibu hamil dengan berat badan berlebih masih terbatas. Tujuan: Penelitian ini bertujuan membandingkan rumus Johnson dan rumus Risanto dalam menentukan TBJ pada ibu hamil dengan berat badan berlebih. Metode: Desain penelitian adalah potong lintang, data diambil di RSU Mitra Sejati, RSU Herna, dan RSU Methodist Sussana Wesley pada November 2019 – Januari 2020. Dilakukan uji Mann-Whitney untuk membandingkan perbedaan rerata TBJ dengan rumus Johnson dan Risanto dengan berat badan lahir. Uji-t berpasangan digunakan untuk membandingkan perbedaan rerata TBJ dengan rumus Johnson dan Risanto. Hasil: Didapatkan 103 ibu hamil yang memenuhi kriteria penelitian dengan rerata IMT 31,26 ± 5l,54 kg/m2. Terdapat perbedaan rerata TBJ rumus Johnson dan rumus Risanto dibandingkan berat badan lahir sebesar 332,45 gram dan 298,57 gram. Tidak terdapat perbedaan rerata bermakna antara penghitungan TBJ menggunakan rumus Johnson dengan berat badan lahir (p = 0,070) dan rumus Risanto dengan berat badan lahir (p = 0,863). Perbedaan selisih TBJ Risanto dengan berat badan lahir lebih rendah dibandingkan selisih TBJ Johnson dengan berat badan lahir, yaitu sebesar 33,88 gram dan bermakna secara statistik (p = 0,01). Kesimpulan: Pengukuran TBJ menggunakan rumus Johnson dan rumus Risanto dapat diterapkan dan digunakan dengan baik oleh tenaga medis. Rumus Risanto memiliki tingkat ketepatan yang lebih baik dibandingkan rumus Johnson dalam menentukan TBJ pada ibu hamil dengan berat badan berlebih.


2017 ◽  
Vol 14 (3) ◽  
pp. 2364
Author(s):  
Saadet Boybay Koyuncu ◽  
Sermin Timur Taşhan

The study aimed to examine the relationship between the gender of newborn with weight gained during pregnancy, mode of delivery and some parameters for newborn. This study used a descriptive and cross-sectional research design. A total of 632 women who gave birth in the postpartum service at a hospital were included in the study. The data were collected using a participant information form prepared by the researcher. Chi-square test and independent sample t-test were used to analyze the data. This study found that the mean pregnancy number and whether the current pregnancy was planned or not were higher for the women whose newborn babies were girls than for those whose newborn babies were boys, and that the mean birth weight of newborn girls was lower than that of newborn boys (p<0.05). No statistically significant relationship was found between the gender of newborn babies and the weight gained during pregnancy, mode of delivery, APGAR score, the time of beginning breastfeeding and giving supplementary food to the newborn babies (p>0.05). This study found that the gender of newborn affected their birth weight and is a determinant factor for the fertility rate of women. In these cases against girls, careful attention of health professionals is needed to ensure continuous and different victimization, close attention to risky couples, is recommended for the development of women's health.Extended English abstract is in the end of PDF (TURKISH) file. ÖzetAraştırma, yenidoğanın cinsiyetinin gebelikte kazanılan kilo, doğum şekli ve yenidoğanın bazı parametreleri ile ilişkisini incelemek amacıyla yapıldı. Araştırma tanımlayıcı ve kesitsel tiptedir. Araştırmaya bir hastanenin postpartum servisinde doğum yapan 632 kadın alındı. Veriler araştırmacı tarafından hazırlanan katılımcı bilgi formu aracılığıyla toplandı. İstatistiksel analizde ki-kare testi, independent sample t testi analizi kullanıldı. Araştırmada, kız yenidoğana sahip olan kadınların ortalama gebelik sayısı ve mevcut gebeliğin planlı olma durumu erkek yenidoğana sahip olanlara göre daha yüksek (p<0.05); kız yenidoğanların ortalama doğum kilosunun ise erkeklere oranla daha düşük olduğu saptandı (p<0.05). Araştırmada yenidoğanın cinsiyeti ile gebelikte kazanılan kilo, doğum şekli, APGAR skor, emzirmeye başlama zamanı ve yenidoğana ilk 24 saat içinde ek gıda verilmesi arasında istatistiksel olarak anlamlı bir ilişki saptanmamıştır (p>0.05). Araştırmada yenidoğan cinsiyetinin yenidoğanın doğum kilosunu etkilediği ve kadının doğurganlık hızında belirleyici bir faktör olduğu belirlenen çalışmada; kadın sağlığının geliştirilmesi için, kız çocuklar aleyhine olan bu durumlarda, sürekli ve farklı mağduriyetlerin yaşanmaması için sağlık profesyonellerinin dikkatli olması, riskli çiftlerin yakından ele alınması önerilmektedir.


PEDIATRICS ◽  
1981 ◽  
Vol 68 (2) ◽  
pp. 175-182
Author(s):  
Yves W. Brans ◽  
Donna L. Shannon ◽  
Rajam S. Ramamurthy

Volumes of plasma (PV), blood (BV), and red cells (RCV) were estimated within 32 hours of birth in 39 neonates with normal growth, 14 neonates with intrauterine growth retardation, and 20 neonates with macrosomia. Total PV, BV, and RCV increased linearly with birth weight and were unaffected by deviation in the quality of fetal growth. In proportion to body weight, PV/kg, BV/kg, and RCV/kg correlated neither with birth weight nor with the quality of intrauterine growth. Neonates with umbilical vein hematocrit (UV Hct) levels 51% to 60%, 61% to 65%, and 66% to 77% had progressively lower, but not statistically different, mean PV/kg (38.1 ± 4.49, 37.6 ± 5.41, and 34.8 ± 5.16 ml/kg, respectively). On the other hand, they had progressively higher mean BV/kg (90 ± 10.1 vs 101 ± 13.7 ml/kg, P &lt; .002, and vs 110 ± 19.0 ml/kg, P &lt; .001). They also had progressively higher mean RCV/kg (52 ± 7.4, 64 ± 8.7, and 75 ± 16.4 ml/kg, P &lt; .001). Although PV/kg did not correlate with UV Hct, both BV/kg and RCV/kg increased linearly with increasing UV Hct (r = .58 and r = .79, respectively). Volume estimates were repeated after partial exchange transfusion in 29 neonates. Mean UV Hct decreased from 63 ± 5.9% preexchange to 51 ± 5.2% postexchange (P &lt; .001), mean PV increased from 37.7 ± 5.56 to 47.6 ± 7.99 ml/kg (P &lt; .001) and mean RCV decreased from 67 ± 16.5 to 51 ± 12.3 ml/kg (P &lt; .001). Despite precautions to keep the partial exchange isovolemic, mean BV decreased from 105 ± 18.7 to 98 ± 18.0 ml/kg (P = .001) and the mean PV increase (10 ml/kg) was less than the mean RCV decrease (16 ml/kg). These data suggest that neonates with polycythemia have normal PV but their RCV and BV are elevated in direct proportion to UV Hct. "Isovolemic" partial exchange transfusion decreases UV Hct, RCV, and BV and increases PV.


Author(s):  
Ntiense Macaulay Utuk ◽  
Anyiekere Ekanem ◽  
Aniekan Monday Abasiattai

Background: Antenatal care is one of the four pillars of safe motherhood and its benefits in preventing adverse feto-maternal outcome is proven. Commencement of antenatal care early has been shown to be key for this benefit to be fully realized. The aim of this study was to determine the antenatal booking pattern of pregnant women and its determinants in our environment.Methods: A cross sectional study of women attending the booking clinic in the University of Uyo Teaching Hospital, Akwa Ibom State, Southern Nigeria over a three-month period.Results: The mean age of the respondents was 28.5 years. The mean gestational age at booking was 18.3 weeks. The majority of the patients were married (94.1%). 68.1% had a post-secondary education. 33.5% of patients were nultiparous, while 3.5% were grand multiparous. The majority of patients (72.4%) booked late for antenatal care. Age group, marital status, mode of delivery was not significantly associated with timing of booking. High levels of patient’s education, high levels of husband’s education as well as grand multiparity were significantly associated with late booking (P<0.05). Majority (65.4%) of patients claimed that it was safe to book at any time during pregnancy.Conclusions: The majority of women booked late for antenatal care. In our study, we have found that general and health education, subsidisation of cost for antenatal care and introduction of focused antenatal care will help to reverse this trend.


2017 ◽  
Vol 11 (2) ◽  
pp. 20-23
Author(s):  
Safiur Rahman Ansari ◽  
Gehanath Baral

Aims: To examine the association between maternal hemoglobin with birth weight.Methods: Cross sectional study of obstetrics database at Paropakar Maternity and Women’s Hospital. Hospital delivery of over 18 years of age women tested for Pearson correlation using SPSS-17.Results: Total of 2085 cases analyzed. There was mean hemoglobin value of 12.05 ± 1.30 (95% CI=11.992-12.103) g/dL and no any significant impact on mode of delivery (p=0.15) and neonatal death (p=0.736). There was a small but a significant correlation (p<0.01) of maternal age with hemoglobin (r = 0.106) and birth weight (r = 0.093); but a very small negative correlation between maternal hemoglobin and birth weight.Conclusions: Optimal maternal hemoglobin during labor rules out any strong correlation with birth weight.


Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
S Miladi ◽  
S Bouzid ◽  
A Fazaa ◽  
L Souabni ◽  
M Sellami ◽  
...  

Abstract Background Juvenile idiopathic arthritis (JIA) is a heterogeneous group of rheumatic diseases characterized by onset before the age of 16. Since the disease starts at an early age, it may lead to socio-professional difficulties in adulthood for JIA patients. This study aimed to describe the professional outcome of a series of 20 JIA patients. Methods A cross-sectional study including patients aged 20 years and more and fulfilling the ILAR criteria for the diagnosis of JIA was carried out. Telephone interviews were conducted. The responders answered questions about family status, current occupation, working h, eventual workplace adjustments, and sick leave frequency. Results Twenty patients answered the questionary; 14 males and 6 females. The mean age of the disease onset was 8 years. The mean age of patients at the time of the study was 24.27 years [20–36]. Polyarticular form was the most frequent (10 cases). Other subtypes diagnosed were systemic (4 cases), enthesitis-related arthritis (5 cases), oligoarticular (one case). Hip arthritis was observed in 8 patients and surgical intervention was needed in three. Eight patients were treated with csDMARDSs and 12 with bDMARDs. Three of our patients were married (aged 24, 34, and 36). Five were still studying: 4 had good grades without absenteeism. However, one patient needed special aid to go to school and had a higher absence rate. Five other patients were full-time college students without absenteeism. Four patients were college graduates. Among them, two were searching for a job for &gt;6 months. The other two were full-time administrative workers with no absenteeism. One patient did need workplace adjustments. Six patients could not work because of their physical disabilities. Conclusion According to our results, a quarter of our patients could not access professional life. Disease activity and hip destruction are the two main factors causing JIA patients to miss out on important personal and professional opportunities.


2021 ◽  
Vol 15 (11) ◽  
pp. 3496-3498
Author(s):  
Nazia Muneer ◽  
Shamaila Shamaun ◽  
Afshan Shahid ◽  
Riffat Jaleel ◽  
Mehreen Iqbal ◽  
...  

Objective: To determine the mean placental birth weight ratio at term in primigravidae Study design: Cross-sectional study Place and Duration: Department of Obstetrics and Gynecology, Civil Hospital Karachi, duration was six months after the approval of synopsis from 1st January 2016 to 30th June 2016 Subjects and Methods: A total of pregnant women who fulfill the inclusion criteria were included in this study. After delivery, baby was weighed by using weight machine and weight of baby was also noted (as per operational definition). After expulsion of complete placenta, placental weight was measured by using weight machine. The placental-birth weight ratio (PBWR) were calculated as ratio of placental weight to neonatal weight multiplied by 100. Results: Mean ± SD of maternal age was 24.77±4.04 with C.I (24.11----25.42) years. Mean ± SD of placental weight was 505.84±99.97 with C.I (489.71----521.97) grams. Out of 150 neonatal babies 101 (67.3%) were male and 49 (32.7%) were female. Mean placental birth weight ratio was found to be 16.82±2.63 with C.I (16.39----17.24). Conclusion: It is to be concluded that placental weight increased according to the birth weight. The placental weight to birth weight ratio decreased slightly with advancing gestational age. Keywords: Placental weight, Birth weight ratio, Labour at term, Primigravidae


2018 ◽  
Vol 18 (3) ◽  
pp. 539-547
Author(s):  
Micaely Cristina dos Santos Tenório ◽  
Marilene Brandão Tenório ◽  
Raphaela Costa Ferreira ◽  
Carolina Santos Mello ◽  
Alane Cabral Menezes de Oliveira

Abstract Objectives: to analyze the factors associated with the birth of small for gestational age (SGA)infants, in a Northeastern Brazilian capital. Methods: a cross-sectional study was carried out with 331 pregnant women and their newborns attending the public health network in the city of Maceió, in 2014. Maternal antenatal data were collected (socioeconomic, lifestyle, clinical and nutritional) as well as data of the newborns (gestational age, mode of delivery, sex, birth weight and length), after delivery. Birth weight was classified according to the INTERGROWTH-21st curves, being considered SGA those below the 10th percentile according to gestational age and gender. The results were analyzed by Poisson regression using a hierarchical model and were expressed as prevalence ratios (PR) and their respective 95% confidence intervals (CI95%). Results: it was verified that 5.1% of the newborns were SGA. Regarding the associated factors, after adjustment of the hierarchical model, the variable working outside the home was associated with the endpoint studied [PR = 0.14; (CI95% = 0.02-0.75); p=0.022]. Conclusions: it was verified a low frequency of SGA infants in the evaluated population. The fact that the mother works outside the home proved to be a protective factor for this condition.


Author(s):  
Nishu Bhushan ◽  
Surinder Kumar ◽  
Dinesh Kumar ◽  
Reema Khajuria

Background: The incidence of obesity has increased to pandemic proportions over the last 20 years. Obesity is a chronic illness which is associated with metabolic disease, nutritional deficiency, musculoskeletal complications and carcinomas. The aim of the study was to evaluate and compare the maternal and perinatal outcome in patients with BMI 20-24.9 kg/m2 (normal), with BMI 25-29.9 kg/m2 (overweight) and with BMI >30 kg/m2 (obese).Methods: This cross-sectional study was conducted on 300 singleton pregnant women with gestational age>37 weeks with cephalic presentation. The selected women were categorized into three groups of 100 each according to their BMI: Category I included normal women (BMI 20-24.9 kg/m2), Category II included overweight women (BMI 25-29.9 kg/m2) and Category III included obese women (BMI >30 kg/m2).Results: There was increased incidence of antepartum complications in obese women. The difference in the occurrence of pre-eclampsia among the three categories was statistically significant (p=0.001). Similarly, more obese women had eclampsia (5%) and gestational diabetes mellitus (6%) as compared to overweight and normal women and the difference was statistically significant in both these complications (p=0.02 for each). The risk of induction of labour was highest in obese women and so was the incidence of caesarean and instrumental deliveries and the difference was statistically significant. The difference in the onset of labour as well as mode of delivery among the three categories was statistically significant (p<0.05). In perinatal outcomes, the difference in mean birth weight of the babies among three categories was statistically significant (p<0.0001). The difference in incidence of low birth weight (<2.5 kg) as well as macrosomia (>4 kg) among babies of three BMI categories was statistically significant (p<0.05). The difference in the incidence of NICU admissions was statistically significant (p=0.02).Conclusions: Obesity is an independent risk factor for adverse pregnancy outcomes and hence preventable steps should be taken for reducing the maternal and perinatal morbidity and mortality.


Author(s):  
S.H. Elbeely ◽  
M.A. AlQurashi

BACKGROUND: Very low birth weight infants born prematurely are at greater risk for growth delays that lead to Ex-utero Growth Restriction (EUGR) during vulnerable periods of organ structural and functional development. There is considerable evidence that early growth failure has adverse effects on long term neurodevelopment in children which often persists into adulthood. METHODS: This is a single-center cross-sectional study on live newborn infants with birth weight ranges from 500 to 1500 grams (VLBW) and gestational age (GA) between 24–32 weeks who were admitted to NICU at KAMC-Jeddah over a 5 year period (2009–2013). This study aims to evaluate predischarge growth pattern of VLBW infants in terms of weight, head circumference (HC) and length and to identify important variables that have influenced such growth pattern. RESULTS: Of the 135 infants included in the final analysis, 68 (50.4%) were male and 67 (49.6%) were female and the mean gestational age was 28.83±2.064 weeks and the mean birth weight 1166.74±256 grams. Ninety-two infants (68%) had discharge weight at ≤10th percentile and forty four (32%) had their weight >10th percentile. HC was the lowest affected among the anthropometric measurements with 42% ≤10th percentile. In terms of linear growth, 62% had their length ≤10th percentile. Amongst infants born ≤750 grams, 71% and 70% had HC and height at ≤10th percentile respectively, at the time of discharge. BPD was significantly associated with EUGR (p = 0.026). CONCLUSIONS: This study demonstrates that almost 2/3rd of VLBW infants born at KAMC-Jeddah with birth weight ≤750 grams were discharged home with EUGR as demonstrated by their weight, length, and HC ≤10th percentile. BPD was found to be significantly associated with EUGR amongst post-natal factors influencing EUGR.


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