Polysomnographic features differentiating disorder of arousals from sleep-related hypermotor epilepsy

SLEEP ◽  
2019 ◽  
Author(s):  
Paola Proserpio ◽  
Giuseppe Loddo ◽  
Frederic Zubler ◽  
Luigi Ferini-Strambi ◽  
Laura Licchetta ◽  
...  

Abstract Objective The differential diagnosis between sleep-related hypermotor epilepsy (SHE) and disorders of arousal (DOA) may be challenging. We analyzed the stage and the relative time of occurrence of parasomnic and epileptic events to test their potential diagnostic accuracy as criteria to discriminate SHE from DOA. Methods Video-polysomnography recordings of 89 patients with a definite diagnosis of DOA (59) or SHE (30) were reviewed to define major or minor events and to analyze their stage and relative time of occurrence. The “event distribution index” was defined on the basis of the occurrence of events during the first versus the second part of sleep period time. A group analysis was performed between DOA and SHE patients to identify candidate predictors and to quantify their discriminative performance. Results The total number of motor events (i.e. major and minor) was significantly lower in DOA (3.2 ± 2.4) than in SHE patients (6.9 ± 8.3; p = 0.03). Episodes occurred mostly during N3 and N2 in DOA and SHE patients, respectively. The occurrence of at least one major event outside N3 was highly suggestive for SHE (p = 2*e-13; accuracy = 0.898, sensitivity = 0.793, specificity = 0.949). The occurrence of at least one minor event during N3 was highly suggestive for DOA (p = 4*e-5; accuracy = 0.73, sensitivity = 0.733, specificity = 0.723). The “event distribution index” was statistically higher in DOA for total (p = 0.012) and major events (p = 0.0026). Conclusion The stage and the relative time of occurrence of minor and major motor manifestations represent useful criteria to discriminate DOA from SHE episodes.

2021 ◽  
Vol 3 (2) ◽  
pp. 115-116
Author(s):  
Ravi Gupta ◽  
Niraj Kumar

Sexual activities during sleep have been reported by some people, often along with the amnesia for the same. Such activities, when involuntary, may arise because of disorders of arousal or may be attributed to sleep related seizures. However, differentiation between the two etiological factors and, also from voluntary acts committed during sleep-period is important not only for the management of disorders but for medicolegal purpose! Subjective information as well gathered by the patients, bed-partners or victims as objective measures, namely polysomnography, long-term video EEG, and neuroimaging techniques may be helpful in achieving the same.


VASA ◽  
2015 ◽  
Vol 44 (2) ◽  
pp. 106-114 ◽  
Author(s):  
Adem Adar ◽  
Hakan Erkan ◽  
Tayyar Gokdeniz ◽  
Aysegul Karadeniz ◽  
Ismail G. Cavusoglu ◽  
...  

Background: We aimed to investigate the association between aortic arch and coronary artery calcification (CAC). We postulated that low‐ and high‐risk CAC scores could be predicted with the evaluation of standard chest radiography for aortic arch calcification (AAC). Patients and methods: Consecutive patients who were referred for a multidetector computerized tomography (MDCT) examination were enrolled prospectively. All patients were scanned using a commercially available 64‐slice MDCT scanner for the evaluation of CAC score. A four‐point grading scale (0, 1, 2 and 3) was used to evaluate AAC on the standard posterior‐anterior chest radiography images. Results: The study group consisted of 248 patients. Median age of the study group was 52 (IQR: 10) years, and 165 (67 %) were male. AAC grades (r = 0.676, p < 0.0001) and age (r = 0.518, p < 0.0001) were significantly and positively correlated with CAC score. Presence of AAC was independently associated with the presence of CAC (OR: 11.20, 95 % CI 4.25 to 29.52). An AAC grade of ≥ 2 was the strongest independent predictor of a high‐risk CAC score (OR: 27.42, 95 % CI 6.09 to 123.52). Receiver operating characteristics curve analysis yielded a strong predictive ability of AAC grades for a CAC score of ≥ 100 (AUC = 0.892, P < 0.0001), and ≥ 400 (AUC = 0.894, P < 0.0001). Absence of AAC had a sensitivity, specificity and accuracy of 90 %, 84 % and 89 %, respectively, for a CAC score of < 100. An AAC grade of ≥ 2 predicted a CAC score of ≥400 with a sensitivity, specificity and accuracy of 68 %, 98 % and 95 %, respectively. Conclusions: AAC is a strong and independent predictor of CAC. The discriminative performance of AAC is high in detecting patients with low‐ and high‐risk CAC scores.


2020 ◽  
Vol 36 (5) ◽  
pp. 777-786 ◽  
Author(s):  
Julia Waldeyer ◽  
Jens Fleischer ◽  
Joachim Wirth ◽  
Detlev Leutner

Abstract. There is substantial evidence that students in higher education who have sophisticated resource-management skills are more successful in their studies. Nevertheless, research shows that students are often not adequately prepared to use resource-management strategies effectively. It is thus crucial to screen and identify students who are at risk of poor resource management (and consequently, reduced academic achievement) to provide them with appropriate support. For this purpose, we extend the validation of a situational-judgment-based instrument called Resource-Management Inventory (ReMI), which assesses resource-management competency (including knowledge of resource-management strategies and the self-reported ability to use this knowledge in learning situations). We evaluated the ReMI regarding factor structure, measurement invariance, and its impact on academic achievement in different study domains in a sample of German first-year students ( N = 380). The results confirm the five-factor structure that has been found in a previous study and indicate strong measurement invariance. Furthermore, taking cognitive covariates into account, the results confirm that the ReMI can predict students’ grades incrementally. Finally, a multi-group analysis shows that the findings can be generalized across different study domains. Overall, we provide evidence for a valid and efficient instrument for the assessment of resource-management competency in higher education.


2018 ◽  
Vol 20 (5) ◽  
pp. 618-622
Author(s):  
Juan Pablo Zavala-Crichton ◽  
Rodrigo Alejandro Yáñez-Sepúlveda ◽  
Nayaded Y. Hernández-García ◽  
Fernando Omar Barraza-Gómez ◽  
Sandra Marcela Mahecha-Matsudo
Keyword(s):  

Objetivo Determinar los efectos del plan gubernamental vida sana en marcadores metabólicos plasmáticos y capacidad física en mujeres sedentarias de Villa Alemana.Métodos Participaron 63 mujeres (41,2 ± 11,2 años) que fueron sometidas a 12 meses de intervención multi e inter-disciplinaria (médico, nutricionista, psicólogo(a) y profesor de educación física) (180 minutos de ejercicio por semana). En el análisis estadístico descriptivo se utilizaron la media y desviación estándar, la prueba T de muestras relacionadas se usó para determinar los efectos del programa, el nivel de significancia se estimó con un valor p<0,05.Resultados Se apreció una disminución en el colesterol total (p=0,003) y colesterol LDL (p=0,048), mejora en el test de 6 minutos (p=0,000) y número de sentadillas en treinta segundos (p=0,000) con un efecto positivo en el delta de recuperación de la frecuencia cardíaca (p=0,001).Conclusión La estrategia gubernamental produjo una disminución en el riesgo cardiovascular debido a una mejora en los marcadores metabólicos y capacidad física de las mujeres.


2012 ◽  
Vol 31 (1) ◽  
pp. 217-251
Author(s):  
Soonmook Lee ◽  
Sun Jung Kwon ◽  
Sung Chil Yeo ◽  
이경희 ◽  
이현정 ◽  
...  
Keyword(s):  

2015 ◽  
Vol 8 (1) ◽  
pp. 1976-1981
Author(s):  
Casey McMahon

The principle postulate of general relativity appears to be that curved space or curved spacetime is gravitational, in that mass curves the spacetime around it, and that this curved spacetime acts on mass in a manner we call gravity. Here, I use the theory of special relativity to show that curved spacetime can be non-gravitational, by showing that curve-linear space or curved spacetime can be observed without exerting a gravitational force on mass to induce motion- as well as showing gravity can be observed without spacetime curvature. This is done using the principles of special relativity in accordance with Einstein to satisfy the reader, using a gravitational equivalence model. Curved spacetime may appear to affect the apparent relative position and dimensions of a mass, as well as the relative time experienced by a mass, but it does not exert gravitational force (gravity) on mass. Thus, this paper explains why there appears to be more gravity in the universe than mass to account for it, because gravity is not the resultant of the curvature of spacetime on mass, thus the “dark matter” and “dark energy” we are looking for to explain this excess gravity doesn’t exist.


Author(s):  
Trần Thanh Đức

This research carried out in Huong Vinh commune, Huong Tra town, Thua Thien Hue province aimed to identify types of land use and soil characteristics. Results showed that five crops are found in Huong Vinh commune including rice, peanut, sweet potato, cassava and vegetable. There are two major soil orders with four soil suborders classified by FAO in Huong Vinh commune including Fluvisols (Dystric Fluvisols<em>, </em>Gleyic Fluvisols and Cambic Fluvisols) and Arenosols (Haplic Arenosols). The results from soil analysis showed that three soil suborders including Dystric Fluvisols<em>, </em>Gleyic Fluvisols and Cambic Fluvisols belonging to Fluvisols were clay loam in texture, low pH, low in OC, total N, total P<sub>2</sub>O<sub>5</sub> and total K<sub>2</sub>O. Meanwhile, the Haplic Arenosols was loamy sand in texture, poor capacity to hold OC, total N, total P<sub>2</sub>O<sub>5</sub> and total K<sub>2</sub>O


Sign in / Sign up

Export Citation Format

Share Document