LATENT DIABETES IN NON-DIABETIC HYPERTENSIVES WITH LEVELS OF FASTING GLUCOSE ≥ 5.6 MMOL/L, A CROSS-SECTIONAL STUDY IN CHINA: PP.17.155

Objectives. The concept now emerging is that higher thyroid-stimulating hormone (TSH) and lower thyroid hormone levels within the euthyroid range may adversely affect atherosclerosis. The present study aimed to investigate the potential associations between thyroid parameters and hyperhomocysteinaemia in a cohort of euthyroid diabetic subjects.Material and Methods. Two hundred and seventy-three euthyroid diabetic subjects (167 males and 106 females) were consecutively recruited in this cross-sectional study. Clinical and biomedical data was collected.Results. TSH level was higher in females than males. Compared to normal-homocysteine group, hyperhomocysteinaemia group was more likely to be elderly, males, with longer diabetes history, and with lower diastolic blood pressure. Free thyroxine (FT4) level was lower in hyperhomocysteinaemia group than in normal-homocysteine group; however, it was not statistically significant. Adjusted for age, sex, body mass index, duration of diabetes, blood pressure, fasting glucose, total cholesterol, and triglyceride in logistic regression analyses, hyperhomocysteinaemia was significantly correlated with FT4 (P=0.021). No significant association was found with TSH or free triiodothyronine. When analyzed in subjects with TSH < 2.5 uIU/mL separately, we got similar results.Conclusions. In conclusion, we identified a relation between hyperhomocysteinemia and FT4 in a group of euthyroid diabetic patients.

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Associations between Dietary Patterns and Impaired Fasting Glucose in Chinese Men: A Cross-Sectional Study

Nutrients ◽

10.3390/nu7095382 ◽

2015 ◽

Vol 7 (9) ◽

pp. 8072-8089 ◽

Cited By ~ 15

Author(s):

Meilin Zhang ◽

Yufeng Zhu ◽

Ping Li ◽

Hong Chang ◽

Xuan Wang ◽

...

Keyword(s):

Impaired Fasting Glucose ◽

Dietary Patterns ◽

Fasting Glucose ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Chinese Men

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Association between Cardiac Autonomic Function, Oxidative Stress and Inflammatory Response in Impaired Fasting Glucose Subjects: Cross-Sectional Study

PLoS ONE ◽

10.1371/journal.pone.0041889 ◽

2012 ◽

Vol 7 (7) ◽

pp. e41889 ◽

Cited By ~ 17

Author(s):

Ramkumar Thiyagarajan ◽

Senthil Kumar Subramanian ◽

Nishanth Sampath ◽

Madanmohan Trakroo ◽

Pravati Pal ◽

...

Keyword(s):

Oxidative Stress ◽

Inflammatory Response ◽

Impaired Fasting Glucose ◽

Autonomic Function ◽

Fasting Glucose ◽

Cross Sectional Study ◽

Cardiac Autonomic Function ◽

Sectional Study ◽

Cross Sectional

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Diabetes mellitus and impaired fasting glucose in ART-naïve patients with HIV-1, HIV-2 and HIV-1/2 dual infection in Guinea-Bissau: a cross-sectional study

Transactions of the Royal Society of Tropical Medicine and Hygiene ◽

10.1093/trstmh/trw017 ◽

2016 ◽

Vol 110 (4) ◽

pp. 219-227 ◽

Cited By ~ 5

Author(s):

Ditte Steiniche ◽

Sanne Jespersen ◽

Christian Erikstrup ◽

Henrik Krarup ◽

Aase Handberg ◽

...

Keyword(s):

Diabetes Mellitus ◽

Impaired Fasting Glucose ◽

Fasting Glucose ◽

Dual Infection ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Guinea Bissau ◽

Hiv 1

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Increased fasting glucose and the prevalence of arterial stiffness: a cross-sectional study in Chinese adults

Neurological Research ◽

10.1179/1743132814y.0000000345 ◽

2014 ◽

Vol 36 (5) ◽

pp. 427-433 ◽

Cited By ~ 11

Author(s):

Jing Wang ◽

Liping Liu ◽

Yong Zhou ◽

Chunxue Wang ◽

Haitao Hu ◽

...

Keyword(s):

Arterial Stiffness ◽

Fasting Glucose ◽

Cross Sectional Study ◽

Sectional Study ◽

Chinese Adults ◽

Cross Sectional

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Non-linear associations of body mass index with impaired fasting glucose, β-cell dysfunction, and insulin resistance in nondiabetic Chinese individuals: a cross-sectional study

Endokrynologia Polska ◽

10.5603/ep.a2021.0073 ◽

2021 ◽

Author(s):

Min Chen ◽

Ruihua Yang ◽

Ying Wang ◽

Yumei Jia ◽

Jia Liu ◽

...

Keyword(s):

Insulin Resistance ◽

Body Mass Index ◽

Body Mass ◽

Impaired Fasting Glucose ◽

Fasting Glucose ◽

Cross Sectional Study ◽

Sectional Study ◽

Β Cell ◽

Cross Sectional ◽

Cell Dysfunction

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Prevalence of Sexual Dysfunction in Women with Type 1, 2 Diabetes and Thyroid Disorder: A Cross-Sectional Study in Taif City, Saudi Arabia

10.21203/rs.3.rs-109530/v1 ◽

2020 ◽

Author(s):

Khalid Alshehri ◽

Raghad Al Thobaiti ◽

Athar Alqurashi ◽

Nada Algethami ◽

Khaled Alswat

Keyword(s):

Sexual Dysfunction ◽

Fasting Glucose ◽

Cross Sectional Study ◽

Thyroid Disorders ◽

Thyroid Disorder ◽

Sectional Study ◽

Cross Sectional ◽

Female Patients ◽

The Impact

Abstract Background: Women with diabetes mellitus or thyroid disorders are at risk of sexual dysfunction. This study aimed to estimate the prevalence of female sexual dysfunction (FSD) in women with diabetes and/or thyroid disorders and the impact of disease control on the ASEX score.Methods: A cross-sectional study for female patients who had a routine clinic visit were included. The Arizona Sexual Experience Scale (ASEX) was used to evaluate for FSD. Those with a total score of ≥ 19 or scored ≥ 5 on any item or ≥ 4 on three items were considered to have FSD.Results: A total of 253 female patients with a mean age of 39.1 ± 7.3 years were included. Two-thirds of the participants have no FSD. More than half (57.7%) of the participants had a strong desire for sex, and about 20% of the participants were unsatisfied with their orgasm. Compared to those with no FSD, those with FSD had lower BMI (P = 0.375), more likely to have a master’s degree or higher (P = 0.117), diabetes (P = 0.879), hypothyroidism (P = 0.625), diabetes-related microvascular and macrovascular complications (P = 0.049), higher HbA1c, fasting glucose, and TSH (P = 0.731, P = 0.161, and P = 0.561, respectively), lower total cholesterol and LDL (P = 0.368 and P = 0.339, respectively), and exercise more regularly (P = 0.929). Conclusion: One-third (32.5%) of the study participants had a FSD. Those with type 1 diabetes had the highest ASEX scores. We detected non-significant negative correlations between total ASEX score and both BMI and TSH, as well as a non-significant positive correlation between total ASEX score and both HbA1c and fasting glucose value.

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Association Between Serum Furin and Fasting Glucose: A Cross-Sectional Study in Chinese Adults

Frontiers in Endocrinology ◽

10.3389/fendo.2021.781890 ◽

2022 ◽

Vol 12 ◽

Author(s):

Yan He ◽

Hanyun Zhu ◽

Min Zhang ◽

Jing Li ◽

Shengqi Ma ◽

...

Keyword(s):

Sex Education ◽

Fasting Glucose ◽

Data Interpretation ◽

Cross Sectional Study ◽

Sectional Study ◽

Chinese Adults ◽

Cross Sectional ◽

Negatively Associated ◽

Increased Risk ◽

Normal Glucose

BackgroundFurin has been associated with glucose metabolic phenotypes in small sampled clinical studies. However, this association has not yet been studied in Chinese. Here, we aimed to examine the association between serum furin and fasting glucose in Chinese adults.MethodsSerum furin and fasting plasma glucose were assayed for 2,172 participants (mean aged 53 years, 38% men) in the Gusu cohort. A median regression model was applied to examine the association between serum furin and fasting glucose, adjusting for age, sex, education level, cigarette smoking, alcohol drinking, obesity, blood pressure, and lipids. To facilitate data interpretation, the association between serum furin and prevalent diabetes was also examined.ResultsSerum furin was negatively associated with fasting glucose (β=-0.18, P<0.001 for log-furin). In participants with diabetes, serum furin was significantly lower than those with normal glucose (median: 0.90 ng/mL vs. 1.05 ng/mL, P=0.001). Compared with participants in the highest quartile of serum furin, those in the lowest quartile had 42% and 80% increased risk of prevalent prediabetes (OR=1.42, 95%CI: 1.05-1.92, P=0.023) and diabetes (OR=1.80, 95%CI: 1.13-2.91, P=0.015), respectively.ConclusionsSerum furin was negatively associated with prediabetes and diabetes in Chinese adults. Our findings suggest that serum furin may be a risk factor or a biomarker of diabetes.

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Premature ovarian failure after childhood cancer and risk of metabolic syndrome – a cross-sectional analysis

Acta Endocrinologica ◽

10.1530/eje-20-1275 ◽

2021 ◽

Author(s):

Axel Netterlid ◽

Helena Mörse ◽

Aleksander Giwercman ◽

Emir Henic ◽

Kristina E Akesson ◽

...

Keyword(s):

Metabolic Syndrome ◽

Childhood Cancer ◽

Fasting Glucose ◽

Childhood Cancer Survivors ◽

Cross Sectional Study ◽

Sectional Study ◽

Ovarian Insufficiency ◽

Cross Sectional ◽

X Ray ◽

Sectional Analysis

Objective: Female childhood cancer survivors (CCS) are at risk of several late effects, among them metabolic syndrome (MetS) and premature ovarian insufficiency (POI). The objective is to study if POI is associated with risk of MetS and increased cardiovascular risk in CSS. Design: A cross-sectional study with a median time since cancer diagnosis of 25 (12 – 41) years. Patients and controls were recruited from the South Medical Region of Sweden. Methods: The study included 167 female CCS, median age 34 (19 – 57) years, diagnosed with childhood cancer at median age 8.4 (0.1 – 17.9) years together with 164 controls, matched for age, sex, ethnicity, residence, and smoking habits. All subjects were examined with fasting glucose, insulin, HbA1c, and lipid profile. Fat mass was calculated with dual-energy X-ray absorptiometry (DXA), questionnaires for medication were obtained. Detailed information of cancer treatment was available. Results: POI was present in 13% (22/167) among CCS (hypothalamic/pituitary cause excluded) and in none among controls. MetS was present in 14% (24/167) among all CCS (p = 0.001), in 23% (5/22) of those with POI (p < 0.001), compared with 4% (6/164) among controls. OR for MetS in all CCS compared with controls was 4.4 (95% CI 1.8, 11.1) (p = 0.002) and among CCS with POI the OR was 7.7 (CI 2.1, 28.1) (p = 0.002). Conclusion: The prevalence of MetS was higher in females treated for childhood cancer compared with controls and the presence of POI significantly increased the risk of developing MetS.

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