scholarly journals Mental Health in UK Biobank Revised – development, implementation and results from an online questionnaire completed by 157,366 participants

2019 ◽  
Author(s):  
Katrina A. S. Davis ◽  
Jonathan R. I. Coleman ◽  
Mark Adams ◽  
Naomi Allen ◽  
Gerome Breen ◽  
...  
Keyword(s):  
Mental Health ◽  
Alcohol Use ◽  
Mental Disorders ◽  
Alcohol Use Disorder ◽  
Bipolar Affective Disorder ◽  
Face Validity ◽  
Common Finding ◽  
Uk Biobank ◽  
Post Traumatic Stress ◽  
Mental Health Questionnaire

AbstractThis paper corrects and updates a paper published in BJPsych Open 2018 “Mental Health in UK Biobank” (https://doi.org/10.1192/bjo.2018.12) that was voluntarily retracted following the finding of errors in the coding of the variable for alcohol use disorder. Notably, the percentage of participants reaching threshold for alcohol use disorder on the Alcohol Use Disorder Identification Tool increased from 7% to 21%.BackgroundUK Biobank is a well-characterised cohort of over 500,000 participants that offers unique opportunities to investigate multiple diseases and risk factors. An online mental health questionnaire completed by UK Biobank participants expands the potential for research into mental disorders.MethodsAn expert working group designed the questionnaire, using established measures where possible, and consulting with a service user group regarding acceptability. Operational criteria were agreed for defining likely disorder and risk states, including lifetime depression, mania/hypomania, generalised anxiety disorder, unusual experiences and self-harm, and current post-traumatic stress and alcohol use disorders.Results157,366 completed online questionnaires were available by August 2017. Comparison of self-reported diagnosed mental disorder with a contemporary study shows a similar prevalence, despite respondents being of higher average socioeconomic status. Lifetime depression was the most common finding in 24% of participants (37,434), with current alcohol use disorder criteria met by 21% (32,602), while other criteria were met by less than 8% of the participants. There was extensive comorbidity among the syndromes. Mental disorders were associated with a high neuroticism score, adverse life events and long-term illness; addiction and bipolar affective disorder in particular were associated with measures of deprivation.ConclusionsThe questionnaire represents a very large mental health survey in itself, and the results presented here show high face validity, although caution is needed due to selection bias. Built into UK Biobank, these data intersect with other health data to offer unparalleled potential for crosscutting biomedical research involving mental health.

scholarly journals Mental health in UK Biobank – development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis

BJPsych Open ◽  
2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Katrina A. S. Davis ◽  
Jonathan R. I. Coleman ◽  
Mark Adams ◽  
Naomi Allen ◽  
Gerome Breen ◽  
...  
Keyword(s):  
Mental Health ◽  
Alcohol Use ◽  
Bipolar Affective Disorder ◽  
Environmental Data ◽  
Face Validity ◽  
Common Finding ◽  
Uk Biobank ◽  
Post Traumatic Stress ◽  
Harmful Alcohol ◽  
Mental Health Questionnaire

Background UK Biobank is a well-characterised cohort of over 500 000 participants including genetics, environmental data and imaging. An online mental health questionnaire was designed for UK Biobank participants to expand its potential. Aims Describe the development, implementation and results of this questionnaire. Method An expert working group designed the questionnaire, using established measures where possible, and consulting a patient group. Operational criteria were agreed for defining likely disorder and risk states, including lifetime depression, mania/hypomania, generalised anxiety disorder, unusual experiences and self-harm, and current post-traumatic stress and hazardous/harmful alcohol use. Results A total of 157 366 completed online questionnaires were available by August 2017. Participants were aged 45–82 (53% were ≥65 years) and 57% women. Comparison of self-reported diagnosed mental disorder with a contemporary study shows a similar prevalence, despite respondents being of higher average socioeconomic status. Lifetime depression was a common finding, with 24% (37 434) of participants meeting criteria and current hazardous/harmful alcohol use criteria were met by 21% (32 602), whereas other criteria were met by less than 8% of the participants. There was extensive comorbidity among the syndromes. Mental disorders were associated with a high neuroticism score, adverse life events and long-term illness; addiction and bipolar affective disorder in particular were associated with measures of deprivation. Conclusions The UK Biobank questionnaire represents a very large mental health survey in itself, and the results presented here show high face validity, although caution is needed because of selection bias. Built into UK Biobank, these data intersect with other health data to offer unparalleled potential for crosscutting biomedical research involving mental health.

scholarly journals RETRACTED – Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants

BJPsych Open ◽  
2018 ◽  
Vol 4 (3) ◽  
pp. 83-90 ◽  
Author(s):  
Katrina A. S. Davis ◽  
Jonathan R. I. Coleman ◽  
Mark Adams ◽  
Naomi Allen ◽  
Gerome Breen ◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
Expert Witness ◽  
Bipolar Affective Disorder ◽  
Face Validity ◽  
Uk Biobank ◽  
Post Traumatic Stress ◽  
Online Questionnaire ◽  
Case Definitions ◽  
Mental Health Questionnaire

Background UK Biobank is a well-characterised cohort of over 500 000 participants that offers unique opportunities to investigate multiple diseases and risk factors. Aims An online mental health questionnaire completed by UK Biobank participants was expected to expand the potential for research into mental disorders. Method An expert working group designed the questionnaire, using established measures where possible, and consulting with a patient group regarding acceptability. Case definitions were defined using operational criteria for lifetime depression, mania, anxiety disorder, psychotic-like experiences and self-harm, as well as current post-traumatic stress and alcohol use disorders. Results 157 366 completed online questionnaires were available by August 2017. Comparison of self-reported diagnosed mental disorder with a contemporary study shows a similar prevalence, despite respondents being of higher average socioeconomic status than the general population across a range of indicators. Thirty-five per cent (55 750) of participants had at least one defined syndrome, of which lifetime depression was the most common at 24% (37 434). There was extensive comorbidity among the syndromes. Mental disorders were associated with high neuroticism score, adverse life events and long-term illness; addiction and bipolar affective disorder in particular were associated with measures of deprivation. Conclusions The questionnaire represents a very large mental health survey in itself, and the results presented here show high face validity, although caution is needed owing to selection bias. Built into UK Biobank, these data intersect with other health data to offer unparalleled potential for crosscutting biomedical research involving mental health. Declaration of interest G.B. received grants from the National Institute for Health Research during the study; and support from Illumina Ltd. and the European Commission outside the submitted work. B.C. received grants from the Scottish Executive Chief Scientist Office and from The Dr Mortimer and Theresa Sackler Foundation during the study. C.S. received grants from the Medical Research Council and Wellcome Trust during the study, and is the Chief Scientist for UK Biobank. M.H. received grants from the Innovative Medicines Initiative via the RADAR-CNS programme and personal fees as an expert witness outside the submitted work.

PTSD, panic disorder and alcohol use disorder as a triple threat for violence among male jail detainees

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Alexa J. Barrett ◽  
Stephanie L. Taylor ◽  
Albert M. Kopak ◽  
Norman G. Hoffmann
Keyword(s):  
Mental Health ◽  
Alcohol Use ◽  
Panic Disorder ◽  
Alcohol Use Disorder ◽  
Health Conditions ◽  
Post Traumatic Stress ◽  
Content Type ◽  
Mental Health Conditions ◽  
Jail Detainees ◽  
Violent Offenses

Purpose Despite ranking among the most prevalent mental health conditions and their likely contributions to violent offending, post-traumatic stress disorder (PTSD), panic disorder (PD) and alcohol use disorder (AUD) have not been examined closely among adult males detained in rural jails. The purpose of this paper is to assess the prevalence of co-occurring PTSD, PD and AUD within this population and identify their associations with violent offenses. Design/methodology/approach The sample consists of 349 males recently booked into local jails. The Comprehensive Addictions and Psychological Evaluation – 5 was administered to assess mental health conditions. Bivariate statistics and multivariate logistic regression were used to examine associations between PTSD, PD, AUD and violent offenses. Findings A disproportionate number of participants met criteria for PTSD, PD and AUD. Co-occurrence was prevalent among detainees booked for violent offenses with 25% reporting symptoms of all three disorders. PD emerged as the strongest single condition associated with violence, while the combination of PTSD, PD and AUD significantly increased the likelihood of violent offenses. Practical implications A better understanding of the relationship between mental health conditions and violent offenses is essential for efficacious assessment and treatment. Appropriately informed mental health care for jail detainees can increase public safety and guide practices for addressing these conditions within criminal justice populations. Originality/value There is limited research on mental health within the rural jail detainee population. To the authors’ knowledge, this is the first study to examine the association between PTSD, PD, AUD and violent offenses drawn from local detention centers.

Increased propensity for violence among female jail detainees with PTSD, panic disorder and alcohol use disorder

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Stephanie L. Taylor ◽  
Alexa J. Barrett ◽  
Albert M. Kopak ◽  
Norman G. Hoffmann
Keyword(s):  
Mental Health ◽  
Alcohol Use ◽  
Panic Disorder ◽  
Alcohol Use Disorder ◽  
Post Traumatic Stress ◽  
Content Type ◽  
Violent Offending ◽  
Jail Detainees ◽  
The Usa ◽  
Violent Offenses

Purpose The female jail population is steadily growing in rural jails across the country. Detainees have high rates of mental health and substance use disorders, some of which are linked to violent offenses. These conditions include post-traumatic stress disorder (PTSD), panic disorder (PD) and alcohol use disorder (AUD). This study aims to examine the associations between these disorders among females charged with violent offenses. Design/methodology/approach The sample consists of 167 female detainees from local rural jails in the USA. To assess participants’ behavioral health, the Comprehensive Addictions and Psychological Evaluation – 5 (CAAPE-5) was administered. The associations between PTSD, PD, AUD and violent offenses were investigated using bivariate statistics and multivariate logistic regression. Findings Over half of the female detainees in the sample met criteria individually for PTSD, PD or AUD, substantiating previous work on prevalence rate. Of the sample, only 10% were charged with violent offenses, from which the predominant condition reported was PTSD. Among detainees arrested for violent offenses, 69% also met criteria for PTSD, 56% for AUD and 44% for PD. Multivariate results indicate AUD was the only significant predictor for violent offenses. Research limitations/implications Female detainees experience trauma and mental health conditions at high rates. Research-informed mental health care may result in increased treatment efficacy. Provided the links between PTSD, PD and AUD, special considerations for this population should address interpersonal factors in treatment that may relate to violent offenses. Originality/value Little research exists examining female jail detainees and the implications of AUD, PTSD and PD on violent offending. To the authors' knowledge, this is the first study to examine the relationship between AUD, PTSD and PD in female jail detainees with violent offenses.

scholarly journals Prevalence of Mental Disorders and Suicidality in Canadian Provinces

2019 ◽  
Vol 64 (11) ◽  
pp. 761-769
Author(s):  
Joshua Palay ◽  
Tamara L. Taillieu ◽  
Tracie O. Afifi ◽  
Sarah Turner ◽  
James M. Bolton ◽  
...  
Keyword(s):  
Mental Health ◽  
Substance Use ◽  
Alcohol Use ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Substance Use Disorders ◽  
Alcohol Use Disorder ◽  
Service Providers ◽  
The Past ◽  
Canadian Provinces

Objective: There is limited information to guide health-care service providers and policy makers on the burden of mental disorders and addictions across the Canadian provinces. This study compares interprovincial prevalence of major depressive disorder (MDD), bipolar disorder, generalized anxiety disorder (GAD), alcohol use disorder, substance use disorders, and suicidality. Method: Data were extracted from the 2012 Canadian Community Health Survey—Mental Health ( n = 25,113), a representative sample of Canadians over the age of 15 years across all provinces. Cross tabulations and logistic regression were used to determine the prevalence and odds of the above disorders for each province. Adjustments for provincial sociodemographic factors were performed. Results: The past-year prevalence of all measured mental disorders and suicidality, excluding GAD, demonstrated significant interprovincial differences. Manitoba exhibited the highest prevalence of any mental disorder (13.6%), reflecting high prevalence of MDD and alcohol use disorder compared to the other provinces (7.0% and 3.8%, respectively). Nova Scotia exhibited the highest prevalence of substance use disorders (2.9%). Quebec and Prince Edward Island exhibited the lowest prevalence of any mental disorder (8.5% and 7.7%, respectively). Manitoba also exhibited the highest prevalence of suicidal ideation (5.1%); however, British Columbia and Ontario exhibited the highest prevalence of suicidal planning (1.4% and 1.3%, respectively), and Ontario alone exhibited the highest prevalence of suicide attempts (0.7%). Conclusions: Significant interprovincial differences were found in the past-year prevalence of mental disorders and suicidality in Canada. More research is necessary to explore these differences and how they impact the need for mental health services.

scholarly journals Tracking the mental health of a nation: prevalence and correlates of mental disorders in the second Singapore mental health study

2019 ◽  
Vol 29 ◽  
Author(s):  
M. Subramaniam ◽  
E. Abdin ◽  
J. A. Vaingankar ◽  
S. Shafie ◽  
B. Y. Chua ◽  
...  
Keyword(s):  
Mental Health ◽  
Bipolar Disorder ◽  
Alcohol Use ◽  
Mental Disorders ◽  
Alcohol Abuse ◽  
Alcohol Use Disorder ◽  
Lifetime Prevalence ◽  
Health Study ◽  
Dsm Iv ◽  
Mental Health Study

Abstract Aims The second Singapore Mental Health Study (SMHS) – a nationwide, cross-sectional, epidemiological survey - was initiated in 2016 with the intent of tracking the state of mental health of the general population in Singapore. The study employed the same methodology as the first survey initiated in 2010. The SMHS 2016 aimed to (i) establish the 12-month and lifetime prevalence and correlates of major depressive disorder (MDD), dysthymia, bipolar disorder, generalised anxiety disorder (GAD), obsessive compulsive disorder (OCD) and alcohol use disorder (AUD) (which included alcohol abuse and dependence) and (ii) compare the prevalence of these disorders with reference to data from the SMHS 2010. Methods Door-to-door household surveys were conducted with adult Singapore residents aged 18 years and above from 2016 to 2018 (n = 6126) which yielded a response rate of 69.0%. The subjects were randomly selected using a disproportionate stratified sampling method and assessed using World Health Organization Composite International Diagnostic Interview version 3.0 (WHO-CIDI 3.0). The diagnoses of lifetime and 12-month selected mental disorders including MDD, dysthymia, bipolar disorder, GAD, OCD, and AUD (alcohol abuse and alcohol dependence), were based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria. Results The lifetime prevalence of at least one mood, anxiety or alcohol use disorder was 13.9% in the adult population. MDD had the highest lifetime prevalence (6.3%) followed by alcohol abuse (4.1%). The 12-month prevalence of any DSM-IV mental disorders was 6.5%. OCD had the highest 12-month prevalence (2.9%) followed by MDD (2.3%). Lifetime and 12-month prevalence of mental disorders assessed in SMHS 2016 (13.8% and 6.4%) was significantly higher than that in SMHS 2010 (12.0% and 4.4%). A significant increase was observed in the prevalence of lifetime GAD (0.9% to 1.6%) and alcohol abuse (3.1% to 4.1%). The 12-month prevalence of GAD (0.8% vs. 0.4%) and OCD (2.9% vs. 1.1%) was significantly higher in SMHS 2016 as compared to SMHS 2010. Conclusions The high prevalence of OCD and the increase across the two surveys needs to be tackled at a population level both in terms of creating awareness of the disorder and the need for early treatment. Youth emerge as a vulnerable group who are more likely to be associated with mental disorders and thus targeted interventions in this group with a focus on youth friendly and accessible care centres may lead to earlier detection and treatment of mental disorders.

scholarly journals Mental Health Over Time in a Military Sample: The Impact of Alcohol Use Disorder on Trajectories of Psychopathology After Deployment

2015 ◽  
Vol 28 (6) ◽  
pp. 547-555 ◽  
Author(s):  
Laura Sampson ◽  
Gregory H. Cohen ◽  
Joseph R. Calabrese ◽  
David S. Fink ◽  
Marijo Tamburrino ◽  
...  
Keyword(s):  
Mental Health ◽  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
The Impact ◽  
Over Time

Economic evaluation and costs of telepsychiatry programmes: A systematic review

2020 ◽  
pp. 1357633X2093891 ◽  
Author(s):  
John A Naslund ◽  
Lauren M Mitchell ◽  
Udita Joshi ◽  
Dipal Nagda ◽  
Chunling Lu
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Mental Disorders ◽  
Clinical Care ◽  
Mental Illnesses ◽  
Economic Evaluations ◽  
Schizophrenia Spectrum Disorders ◽  
Post Traumatic Stress

Objective Telepsychiatry involves use of telecommunications technology to deliver psychiatric care and offers promise to reduce costs and increase access to mental health services. This systematic review examined cost reporting of telepsychiatry programmes for mental healthcare. Methods We systematically searched electronic databases for studies reporting costs, including economic evaluations such as cost-effectiveness analyses, or costs of developing telepsychiatry programmes for clinical care of mental disorders. Included studies enrolled participants with mental disorders and involved telepsychiatry for depression, anxiety disorders, serious mental illnesses including schizophrenia spectrum disorders and bipolar disorder, post-traumatic stress disorder, dementia or epilepsy. Results Twenty-six unique studies met inclusion criteria (17,967 participants), with most targeting depression ( n = 7; 27%), general mental disorders and screening ( n = 7; 27%), child mental health ( n = 4; 15%) and geriatric mental health ( n = 4; 15%). Nearly all studies ( n = 25; 96%) compared telepsychiatry programme costs with either standard in-person consultation or usual care, with 15 (60%) reporting that telepsychiatry programmes were less expensive, and 8 (32%) showing telepsychiatry programmes were more expensive. Three studies reported cost-effectiveness analyses, favouring telepsychiatry programmes, but at highly elevated cost-effectiveness thresholds. Few studies reported costs of developing or delivering telepsychiatry programmes. Conclusion Costs of telepsychiatry programmes varied widely, with substantial heterogeneity in how costs were defined and reported. Some programmes cost less than in-person services while others cost more. Therefore, rigorous cost-effectiveness studies following established standards in economic evaluation are needed to inform implementation and sustainability of these programmes in health systems.

scholarly journals Effectiveness of psychological treatments for depression and alcohol use disorder delivered by community-based counsellors: two pragmatic randomised controlled trials within primary healthcare in Nepal

2019 ◽  
Vol 215 (2) ◽  
pp. 485-493 ◽  
Author(s):  
Mark J. D. Jordans ◽  
Nagendra P. Luitel ◽  
Emily Garman ◽  
Brandon A. Kohrt ◽  
Sujit D. Rathod ◽  
...  
Keyword(s):  
Mental Health ◽  
Primary Care ◽  
Alcohol Use ◽  
Randomised Controlled Trials ◽  
Alcohol Use Disorder ◽  
Controlled Trials ◽  
Community Based ◽  
Psychological Treatments ◽  
Randomised Controlled ◽  
Healthy Activity

BackgroundEvidence shows benefits of psychological treatments in low-resource countries, yet few government health systems include psychological services.AimEvaluating the clinical value of adding psychological treatments, delivered by community-based counsellors, to primary care-based mental health services for depression and alcohol use disorder (AUD), as recommended by the Mental Health Gap Action Programme (mhGAP).MethodTwo randomised controlled trials, separately for depression and AUD, were carried out. Participants were randomly allocated (1:1) to mental healthcare delivered by mhGAP-trained primary care workers (psychoeducation and psychotropic medicines when indicated), or the same services plus individual psychological treatments (Healthy Activity Program for depression and Counselling for Alcohol Problems). Primary outcomes were symptom severity, measured using the Patient Health Questionnaire – 9 item (PHQ-9) for depression and the Alcohol Use Disorder Identification Test for AUD, and functional impairment, measured using the World Health Organization Disability Assessment Schedule (WHODAS), at 12 months post-enrolment.ResultsParticipants with depression in the intervention arm (n = 60) had greater reduction in PHQ-9 and WHODAS scores compared with participants in the control (n = 60) (PHQ-9: M = −5.90, 95% CI −7.55 to −4.25, β = −3.68, 95% CI −5.68 to −1.67, P < 0.001, Cohen's d = 0.66; WHODAS: M = −12.21, 95% CI −19.58 to −4.84, β = −10.74, 95% CI −19.96 to −1.53, P= 0.022, Cohen's d = 0.42). For the AUD trial, no significant effect was found when comparing control (n = 80) and intervention participants (n = 82).ConclusionAdding a psychological treatment delivered by community-based counsellors increases treatment effects for depression compared with only mhGAP-based services by primary health workers 12 months post-treatment.Declaration of interestNone.

Sign in / Sign up

Export Citation Format

Share Document