scholarly journals “A compressed representation of spatial distance in the rodent hippocampus’’

2021 ◽  
Author(s):  
Daniel J. Sheehan ◽  
Stephen Charczynski ◽  
Blake A. Fordyce ◽  
Michael E. Hasselmo ◽  
Marc W. Howard
Keyword(s):  
Spatial Location ◽  
Place Cells ◽  
Spatial Distance ◽  
Spatial Relationships ◽  
Time And Space ◽  
The Past ◽  
Starting Point ◽  
Starting Location ◽  
Stimulus Offset ◽  
Representation Of Time

AbstractPrincipal cells in the rodent hippocampus often fire in response to traversal through a specific spatial location (place cells), as well as elapsed time during an imposed temporal delay or after stimulus offset (time cells). Sequences of time cells unfold rapidly at first, with many time cells with narrow time fields. As the triggering event recedes into the past, time cells are fewer and have broader fields. This means that the representation of time in the hippocampus is compressed with greater resolution for time points near the present. Using tetrode recordings we measured individual CA1 units while rats traveled along a track that could be changed in length. Consistent with previous results, most place cells coded for distance from the starting point of the trajectory. Critically, place cells became less numerous and showed gradually widening fields with distance from the starting location. These results suggest that as the animal leaves a landmark, the hippocampal place code forms a compressed representation of distance from the starting location. The representation of time and space in the hippocampus have similar properties suggesting that they arise from similar computational mechanisms.Significance StatementThe hippocampus represents relationships between events in time and space. It has been hypothesized that temporal and spatial relationships are the result of a common computational mechanism. Previous work has shown that the representation of time in the hippocampus is compressed, with less neural resolution for more temporally remote events, consistent with the observation that temporal memory is worse for events further in the past. This paper shows an analogous result for spatial relationships. Place cells coded for distance from the start of a journey. As distance increased, place fields became broader and less numerous, showing a decrease in spatial resolution. This result suggests a unified coding scheme for the dimensions of time and space in the rodent hippocampus.

scholarly journals THE PECULIARITIES OF REPRESENTATION OF TIME ANS SPACE MODEL IN THE COLLECTION OF STORIES «WESSEX TALES» BY T.HARDY

2020 ◽  
Vol 1 (10(78)) ◽  
pp. 167-170
Author(s):  
Olena Rosstalna
Keyword(s):  
Contextual Analysis ◽  
Community Life ◽  
Moral Choice ◽  
Time And Space ◽  
Space Model ◽  
The Past ◽  
Space Organization ◽  
Characteristic Features ◽  
Local Image ◽  
Representation Of Time

The article analyzes the peculiarities of the representation of time and space model in the collection of short stories «Wessex Tales» by the English writer T.Hardy. Based on a contextual analysis of T. Hardy’s stories, time and space model was singled out as the dominant meaning for the creation of «Wessex Tales». It is proved that the category of time in «Wessex Tales» is a component of the composition of works (in some stories the principle of framing is used). Its functioning in the collection occurs in the form of a two-component model, the elements of which are past and present. It is determined that the specific presentation of the past is a combination of «collective» and «individual» time. While presenting individual facts in the lives of specific heroes in the form of «individual» time, the author introduces them into the context of events of community life in the form of «collective» time. Each individual character’s story thus becomes a part of panoramic depiction of Wessex world, while maintaining a connection with real historical events. «Quasi-historicity» is defined as one of the characteristic features of time. The interaction of temporal levels has also been investigated at the level of conflicts and problems in the writer’s stories and novels (the problem of responsibility for actions, the problem of moral choice, etc.). The peculiarity of space organization in the collection of stories is determined by multilevel (panoramic – local image; realistic – mythopoeticized sketches of the metaphorical plan; the existence of two subspaces in the mythologized model of the world) and multivariate. The article analyzes the closed and open, terrestrial and cosmic, real and imaginary spaces that are realized in the system of images (city, town, house, road, etc.).

Memory and its offspring: Realism and the “specious present”

2018 ◽  
Vol 28 (2) ◽  
pp. 172-192
Author(s):  
Terence McMullen
Keyword(s):  
William James ◽  
Mental Representations ◽  
Spatial Location ◽  
Time And Space ◽  
Specious Present ◽  
Temporal Duration ◽  
The Past ◽  
Metaphysics Of Time ◽  
Direct Apprehension

Without memory we could not recall events, nor could we imagine, image, or expect things. Representationist accounts of memory claim that to remember is to access stored representations of past events. This is logically impossible: there are no such things as mental representations. Memory is the direct apprehension of past events. Some assert that this claim involves the temporal absurdity of supposing that the past can be known directly in the present. There is no such absurdity: cognition and its objects have temporal duration as well as spatial location. Situations perceived and remembered are extended temporally as well as spatially. William James drew attention to the specious present, the belief that we live in a temporally unextended now. A solid ontological account of the metaphysics of time and space is provided uniquely in the empiricist metaphysics of John Anderson’s realism.

Holism, Chinese Medicine and Systems Ideologies: Rewriting the Past to Imagine the Future

2018 ◽  
Author(s):  
Volker Scheid
Keyword(s):  
Eighteenth Century ◽  
Chinese Medicine ◽  
Medical Humanities ◽  
Science And Technology Studies ◽  
Human Beings ◽  
The Past ◽  
Starting Point ◽  
The Us ◽  
Shared Objective ◽  
Definition Of

This chapter explores the articulations that have emerged over the last half century between various types of holism, Chinese medicine and systems biology. Given the discipline’s historical attachments to a definition of ‘medicine’ that rather narrowly refers to biomedicine as developed in Europe and the US from the eighteenth century onwards, the medical humanities are not the most obvious starting point for such an inquiry. At the same time, they do offer one advantage over neighbouring disciplines like medical history, anthropology or science and technology studies for someone like myself, a clinician as well as a historian and anthropologist: their strong commitment to the objective of facilitating better medical practice. This promise furthermore links to the wider project of critique, which, in Max Horkheimer’s definition of the term, aims at change and emancipation in order ‘to liberate human beings from the circumstances that enslave them’. If we take the critical medical humanities as explicitly affirming this shared objective and responsibility, extending the discipline’s traditional gaze is not a burden but becomes, in fact, an obligation.

Disciplining Polenta: A Parody on the Politics of Saving Food

2020 ◽  
Vol 20 (2) ◽  
pp. 1-11
Author(s):  
Zachary Nowak ◽  
Bradley M. Jones ◽  
Elisa Ascione
Keyword(s):  
Food Products ◽  
Social Value ◽  
Traditional Food ◽  
Traditional Foods ◽  
Time And Space ◽  
Historical Sources ◽  
Scholarly Literature ◽  
Identity Creation ◽  
The Past ◽  
The Social

This article begins with a parody, a fictitious set of regulations for the production of “traditional” Italian polenta. Through analysis of primary and secondary historical sources we then discuss the various meanings of which polenta has been the bearer through time and space in order to emphasize the mutability of the modes of preparation, ingredients, and the social value of traditional food products. Finally, we situate polenta within its broader cultural, political, and economic contexts, underlining the uses and abuses of rendering foods as traditional—a process always incomplete, often contested, never organic. In stirring up the past and present of polenta and placing it within both the projects of Italian identity creation and the broader scholarly literature on culinary tradition and taste, we emphasize that for so-called traditional foods to be saved, they must be continually reinvented.

Cyber Peacekeeping: Critical Evaluation of Digital Blue Helmets Program

2020 ◽  
pp. 17-27
Author(s):  
Fahad Nabeel
Keyword(s):  
United Nations ◽  
Critical Evaluation ◽  
Threat Detection ◽  
Information And Communications Technologies ◽  
The Past ◽  
Research Article ◽  
Un Peacekeeping ◽  
Starting Point ◽  
Communications Technologies ◽  
Future Potential

In 2016, the United Nations (UN) launched the Digital Blue Helmets (DBH) program under its Office of Information and Communications Technologies (OICT). The launching of DBH was a continuation of a series of steps that the UN and its related agencies and departments have undertaken over the past decade to incorporate cyberspace within their working methodologies. At the time of inception, DBH was envisioned as a team capacitated to act as a replica of a physical peacekeeping force but for the sole purpose of overseeing cyberspace(s). Several research studies have been published in the past few years, which have conceptualized cyber peacekeeping in various ways. Some scholars have mentioned DBH as a starting point of cyber peacekeeping while some have proposed models for integration of cyber peacekeeping within the current UN peacekeeping architecture. However, no significant study has attempted to look at how DBH has evolved since its inception. This research article aims to examine the progress of DBH since its formation. It argues that despite four years since its formation, DBH is still far away from materializing its declared objectives. The article also discusses the future potential roles of DBH, including its collaboration with UN Global Pulse for cyber threat detection and prevention, and embedding the team along with physical peacekeepers.

‘I AM’: Indigenous consciousness for authenticity and leadership

Leadership ◽  
2021 ◽  
pp. 174271502199959
Author(s):  
Chellie Spiller
Keyword(s):  
True Self ◽  
The Past ◽  
Starting Point ◽  
The Future

This article encourages a move away from the excessively inward gaze of ‘to thine own self be true’ and explores ‘I AM’ consciousness as a starting point. An I AM approach encourages a move from the measurable self to the immeasurable expansiveness and mystery of our own becoming. It is to step beyond the lines drawn around the ‘true self’ or the lines that others would have us draw. I AM consciousness reflects an ancient Indigenous thread that echoes through millennia and reminds humans that we are a movement through time, and each person is a present link to the past and the future, woven into a fabric of belonging.

scholarly journals Hepatitis and tuberculosis testing are much less common than HIV testing among adults in Kisumu, Kenya: results from a cross-sectional assessment

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Joshua Tunnage ◽  
Adam Yates ◽  
Chiaka Nwoga ◽  
Valentine Sing’oei ◽  
John Owuoth ◽  
...  
Keyword(s):  
Secondary Education ◽  
Viral Hepatitis ◽  
Hiv Testing ◽  
Spatial Location ◽  
Tuberculosis Screening ◽  
Cross Sectional ◽  
The Past ◽  
Prior Testing ◽  
Testing Uptake ◽  
One Year

Abstract Background Kenya has a high burden of HIV, viral hepatitis, and tuberculosis. Screening is necessary for early diagnosis and treatment, which reduces morbidity and mortality across all three illnesses. We evaluated testing uptake for HIV, viral hepatitis, and tuberculosis in Kisumu, Kenya. Methods Cross-sectional data from adults aged 18–35 years who enrolled in a prospective HIV incidence cohort study from February 2017 to May 2018 were analyzed. A questionnaire was administered to each participant at screening for study eligibility to collect behavioral characteristics and to assess prior testing practices. Among participants without a history of previously-diagnosed HIV, multivariable robust Poisson regression was used to estimate prevalence ratios (PRs) and 95% confidence intervals (CIs) for factors potentially associated with HIV testing in the 12 months prior to enrollment. A hierarchical model was used to test for differential access to testing due to spatial location. Results Of 671 participants, 52 (7.7%) were living with HIV, 308 (45.9%) were female, and the median age was 24 (interquartile range 21–28) years. Among 651 (97.0%) who had ever been tested for HIV, 400 (61.2%) reported HIV testing in the past 6 months, 129 (19.7%) in the past 6–12 months, and 125 (19.1%) more than one year prior to enrollment. Any prior testing for viral hepatitis was reported by 8 (1.2%) participants and for tuberculosis by 51 (7.6%). In unadjusted models, HIV testing in the past year was more common among females (PR 1.08 [95% CI 1.01, 1.17]) and participants with secondary education or higher (PR 1.10 [95% CI 1.02, 1.19]). In the multivariable model, only secondary education or higher was associated with recent HIV testing (adjusted PR 1.10 [95% CI 1.02, 1.20]). Hierarchical models showed no geographic differences in HIV testing across Kisumu subcounties. Conclusions Prior HIV testing was common among study participants and most had been tested within the past year but testing for tuberculosis and viral hepatitis was far less common. HIV testing gaps exist for males and those with lower levels of education. HIV testing infrastructure could be leveraged to increase access to testing for other endemic infectious diseases.

scholarly journals Quality and Operations Management in Food Supply Chains: A Literature Review

2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Yong He ◽  
Hongfu Huang ◽  
Dong Li ◽  
Chunming Shi ◽  
Sarah J. Wu
Keyword(s):  
Literature Review ◽  
Supply Chains ◽  
Operations Research ◽  
Operations Management ◽  
Food Supply ◽  
Research Field ◽  
Food Supply Chains ◽  
The Past ◽  
Starting Point

We present a literature review on quality and operations management problems in food supply chains. In food industry, the quality of the food products declines over time and should be addressed in the supply chain operations management. Managing food supply chains with operations management methods not only generates economic benefit, but also contributes to environmental and social benefits. The literature on this topic has been burgeoning in the past few years. Since 2005, more than 100 articles have been published on this topic in major operations research and management science journals. In this literature review, we concentrate on the quantitative models in this research field and classify the related articles into four categories, that is, storage problems, distribution problems, marketing problems, and food traceability and safety problems. We hope that this review serves as a reference for interested researchers and a starting point for those who wish to explore it further.

Radical Tense-Indexical Historicality and the De Se

KronoScope ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 7-27
Author(s):  
Carl Humphries
Keyword(s):  
Alternative View ◽  
The Past ◽  
Starting Point ◽  
De Se ◽  
Temporal Expressions ◽  
The Subject ◽  
The One ◽  
Self Reference ◽  
A Current ◽  
Shed Light

Abstract “Being is said in many ways,” claimed Aristotle, initiating a discussion about existential commitment that continues today. Might there not be reasons to say something similar about “having been,” or “having happened,” where these expressions denote something’s being located in the past? Moreover, if history – construed not only as an object of inquiry (actual events, etc.) but also as a way of casting light on certain matters – is primarily concerned with “things past,” then the question just posed also seems relevant to the question of what historical understanding amounts to. While the idea that ‘being’ may mean different things in different contexts has indisputable importance, the implications of other, past-temporal expressions are elusive. In what might any differences of substantive meaning encountered there consist? One starting point for responding – the one that provides the subject matter explored here – is furnished by the question of whether or not a certain way of addressing matters relating to the past permits or precludes forms of intelligibility that could be said to be ‘radically historical.’ After arguing that the existing options for addressing this issue remain unsatisfactory, I set out an alternative view of what it could mean to endorse or reject such an idea. This involves drawing distinctions and analogies connected with notions of temporal situatedness, human practicality and historicality, which are then linked to a further contrast between two ways of understanding the referential significance of what is involved when we self-ascribe a relation to a current situation in a manner construable as implying that we take ourselves to occupy a unique, yet circumstantially defined, perspective on that situation. As regards the latter, on one reading, the specific kind of indexically referring language we use – commonly labelled “de se” – is something whose rationale is exhausted by its practical utility as a communicative tool. On the other, it is viewed as capturing something of substantive importance about how we can be thought of as standing in relation to reality. I claim that this second reading, together with the line of thinking about self-identification and self-reference it helps foreground, can shed light on what it would mean to affirm or deny the possibility of radically historical forms of intelligibility – and thus also on what it could mean to ascribe a plurality of meanings to talk concerning things being ‘in the past.’

Time and space problems in the text of epos

2020 ◽  
Vol 60 (11) ◽  
pp. 143-146
Author(s):  
Parvana Ismayil Pashayeva ◽  
Keyword(s):  
Key Words ◽  
Time Pass ◽  
Time And Space ◽  
Physical Time ◽  
The Past ◽  
The Future ◽  
Time Changes

The article deals with the problems of introducing of time, time changes and the time-place relations as well. Artistic time is distinguished by belonging of an artistic time to the past in the artistic text, and in epos texts as well. In such kinds of texts one can meet with the changing of situations and various forms of substitutions of grammatical time. Speech moment can be used in defining of criteria for the present, past and the future times in epos texts. And speech moment is being connected with the physical time. Grammatical time comes into effect as a result of time pass components of physical time changings of course. Key words: time, place, epos, artistic time, grammatical time

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