COVID-19 mortality across selected states in India: the role of age structure.

Background Mortality rates provide an opportunity to identify and act on the health system intervention for preventing deaths. Hence, it is essential to appreciate the influence of age structure while reporting mortality for a better summary of the magnitude of the epidemic. Objectives We described and compared the pattern of COVID-19 mortality standardized by age between selected states and India from January to November 2020. Methods We initially estimated the Indian population for 2020 using the decadal growth rate from the previous census (2011). This was followed by estimations of crude and age-adjusted mortality rate per million for India and the selected states. We used this information to perform indirect standardization and derive the age-standardized mortality rates for the states for comparison. In addition, we derived a ratio for age-standardized mortality to compare across age groups within the state. We extracted information regarding COVID-19 deaths from the Integrated Disease Surveillance Programme special surveillance portal up to November 16, 2020. Results The crude mortality rate of India stands at 88.9 per million population(118,883/1,337,328,910). Age-adjusted mortality rate (per million) was highest for Delhi (300.5) and lowest for Kerala (35.9).The age-standardized mortality rate (per million) for India is (<15 years=1.6, 15-29 years=6.3, 30-44 years=35.9, 45-59 years=198.8, 60-74 years=571.2, & ≥75 years=931.6). The ratios for age-standardized mortality increase proportionately from 45-59 years age group across all the states. Conclusion There is high COVID-19 mortality not only among the elderly ages, but we also identified heavy impact of COVID-19 on the working population. Therefore, we recommend further evaluation of age-adjusted mortality for all States and inclusion of variables like gender, socio-economic status for standardization while identifying at-risk populations and implementing priority public health actions. Keywords COVID-19, Mortality, Age Standardized Mortality Rate, Indirect Standardization.

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Mortality from endometrial cancer in female population of Belgrade

Vojnosanitetski pregled ◽

10.2298/vsp0403267p ◽

2004 ◽

Vol 61 (3) ◽

pp. 267-272

Author(s):

Vesna Pantovic ◽

Mirjana Jarebinski ◽

Tatjana Pekmezovic ◽

Anita Knezevic ◽

Darija Kisic

Keyword(s):

Endometrial Cancer ◽

Mortality Rate ◽

Malignant Tumors ◽

Age Groups ◽

Mortality Rates ◽

Mortality Decline ◽

Female Population ◽

Average Percentage ◽

Standardized Mortality Rate

Data about mortality from malignant tumors of endometrium were analyzed in the Belgrade area during the period 1975-2000. The obtained results showed that the average percentage of endometrial cancer in mortality structure from all the cancers of female population was 2.65%. During the observed 26-years period, malignant tumors of endometrium constituted 17.38% of all the tumors of gynecological localization. The standardized mortality rate in 1975 (population worldwide used as a standard) 7.06/100 000 population while in 2000 it was 1.78/100 000 population, respectively, which showed almost fourfold mortality decline during the observed period (y=4.72-0.16x). A trend of declining risk of dying from endometrial cancer was present in all the age groups. The obtained results indicated that in the observed period the average mortality rates ranged from 0.14/100 000 population in females aged up to 34 years (y=0.30-0.01x), and reached the highest value in females aged 65-74 years (14.57/100 000; y=23.43-0.66x), and 75 years of age and over (19.62/100 000; y=31.17-0.85x).

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Mortality rates due to diseases of the circulatory system in Karachay-Cherkess republic in 2006 and 2014

Kazan medical journal ◽

10.17750/kmj2015-611 ◽

2016 ◽

Vol 97 (4) ◽

pp. 611-618

Author(s):

I V Samorodskaya ◽

E V Bolotova ◽

F Y Bidzhieva

Keyword(s):

Myocardial Infarction ◽

Heart Disease ◽

Mortality Rate ◽

Age Groups ◽

Circulatory System ◽

Mortality Rates ◽

Recurrent Myocardial Infarction ◽

Circulatory System Diseases ◽

Causes Of Deaths ◽

Standardized Mortality Rate

Aim. To study mortality rates due to diseases of the circulatory system and certain nosological forms in Karachay-Cherkess Republic in 2006 and 2014.Methods. The data of the Russian Federation Federal State Statistics Service on the number of deaths according to a short nomenclature of causes of deaths were analyzed. The nosological structure was studied, proportion of each of the causes of death in the total number of deaths from circulatory system diseases was defined. The names of groups of short nomenclature of causes of deaths in 2006 and 2014 were compared. Non-standardized and standardized mortality rates were calculated.Results. Standardized mortality rate due to circulatory diseases decreased by 29.3% in 2014 in comparison with 2006. The decline in mortality due to circulatory system diseases was noted in all age groups, except for the age group 25-29 years (+18.5%) and 60-64 years (+4.2%). Deaths due to primary and recurrent myocardial infarction decreased (by 46.2%) in all age groups except the age of 40-44 years and 80-84 years, in which the mortality rate due to primary and recurrent myocardial infarction increased by 12.5 and 49.4%, respectively. The mortality from ischemic heart disease increased in age 35-39 years (by 11.3%) and 40-44 years (39.4%). In other age groups, the mortality from ischemic heart disease decreased, the maximum reduction was reported in age 65-69 years (54.8%). Standardized mortality rate due to cerebrovascular diseases decreased by 44.06% in 2014 in comparison with 2006.Conclusion. Taking into account significant contribution to the mortality structure due to circulatory system diseases number of deaths, causes of which are not clearly classified and cause problems with clinical interpretation, this issue requires attention of cardiologists, in terms of both health care delivery and specification of the patients’ health status.

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Epidemiological Characteristics of Cancer in Elderly Chinese

ISRN Oncology ◽

10.5402/2012/381849 ◽

2012 ◽

Vol 2012 ◽

pp. 1-5

Author(s):

Xiao Nong Zou ◽

Xia Wan ◽

Zhen Dai ◽

Gong Huan Yang

Keyword(s):

Lung Cancer ◽

Disease Surveillance ◽

Preventive Intervention ◽

Age Groups ◽

The Elderly ◽

Cancer Registries ◽

Mortality Rates ◽

World Population ◽

Elderly Chinese ◽

Epidemiological Characteristics

Background. Population of elder Chinese has been increasing, but the pattern and trend of cancer in that population was rarely reported. Methods. Mortality rates for cancer of all sites and of the site specific of the overall and elderly Chinese from 2004 to 2005 were estimated. The age structure of world population was used to observe the changes in the age-standardized mortality rates from 1975 to 2005 using the data from the national death surveys, Disease Surveillance Points, and cancer registries in China. Results. The mortalities among the elderly Chinese were 782.12 per 100,000, substantially higher than those of the people less than 60 years old. The mortalities for cancers of lung, stomach, liver, and esophagus in elderly population showed great increase compared to younger ages. Stomach cancer ranked as the second most common cancer following lung cancer in the elderly, and those two malignancies had similar mortality rates in male elderly, while in female, it ranked as first, surpassed lung cancer. Consistent decreased trends of M/I ratios of cancer were observed in all age groups. Conclusion. Strategies in cancer prevention and cost-effective preventive intervention should be highly considered and strongly implemented among the elderly Chinese.

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Outcome in an Urban Pediatric Trauma System with Unified Prehospital Emergency Medical Services Care

Prehospital and Disaster Medicine ◽

10.1017/s1049023x00041601 ◽

1995 ◽

Vol 10 (1) ◽

pp. 19-23 ◽

Cited By ~ 11

Author(s):

Michael J. VanRooyen ◽

Edward P. Sloan ◽

John A. Barrett ◽

Robert F. Smith ◽

Hernan M. Reyes

Keyword(s):

Head Injury ◽

Mortality Rate ◽

Trauma Center ◽

Pediatric Trauma ◽

Trauma System ◽

Age Groups ◽

Mortality Rates ◽

Trauma Centers ◽

Field Triage ◽

Pediatric Trauma Center

AbstractHypothesis:Pediatric mortality is predicted by age, presence of head trauma, head trauma with a low Glasgow Coma Scale (GCS) score, a low Pediatric Trauma Score (PTS), and transport directly to a pediatric trauma center.Population:Studied were 1,429 patients younger than 16 years old admitted to or declared dead on arrival (DOA) in a pediatric trauma center from January through October, 1988. The trauma system, which served 3-million persons, included six pediatric trauma centers.Methods:Data were obtained by a retrospective review of summary statistics provided to the Chicago Department of Health by the pediatric trauma centers.Results:Overall mortality was 4.8% (68 of 1429); 32 of the patients who died (47.1%) were DOA. The in-hospital mortality rate was 2.6%. Head injury was the principal diagnosis in 46.2% of admissions and was a factor in 72.2% of hospital deaths. The mortality rate was 20.3% in children with a GCS≤10 and 0.4% when the GCS was >10 (odds ratio [OR] = 67.0, 95% CI = 15.0–417.4). When the PTS was ≤ 5, mortality was 25.6%; with a PTS > 5, the mortality was 0.2% (OR = 420.7, 95% CI = 99.3–2,520). Although transfers to a pediatric trauma center accounted for 73.6% of admissions, direct field triage to a pediatric trauma center was associated with a 3.2 times greater mortality risk (95% CI = 1.58–6.59). Mortality rates were equal for all age groups. Pediatric trauma center volume did not influence mortality rates.Conclusions:Head injury and death occur in all age groups, suggesting the need for broad prevention strategies. Specific GCS and PTS values that predict mortality can be used in emergency medical services (EMS) triage protocols. Although the high proportion of transfers mandates systemwide transfer protocols, the lower mortality in these patients suggests appropriate EMS field triage. These factors should be considered as states develop pediatric trauma systems.

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Endovascular Aortic Repair in Patients of Advanced Age

Journal of Endovascular Therapy ◽

10.1177/15266028211049342 ◽

2021 ◽

pp. 152660282110493

Author(s):

Mitri K. Khoury ◽

Micah A. Thornton ◽

Christopher A. Heid ◽

Jacqueline Babb ◽

Bala Ramanan ◽

...

Keyword(s):

Mortality Rate ◽

Survival Benefit ◽

Elective Surgery ◽

Endovascular Aneurysm Repair ◽

The Elderly ◽

Mortality Rates ◽

Current Data ◽

Aortic Aneurysms ◽

Advanced Age ◽

The Impact

Purpose: Treatment decisions for the elderly with abdominal aortic aneurysms (AAAs) are challenging. With advancing age, the risk of endovascular aneurysm repair (EVAR) increases while life expectancy decreases, which may nullify the benefit of EVAR. The purpose of this study was to quantify the impact of EVAR on 1-year mortality in patients of advanced age. Materials and Methods: The 2003–2020 Vascular Quality Initiative Database was utilized to identify patients who underwent EVAR for AAAs. Patients were included if they were 80 years of age or older. Exclusions included non-elective surgery or missing aortic diameter data. Predicted 1-year mortality of untreated AAAs was calculated based on a validated comorbidity score that predicts 1-year mortality (Gagne Index, excluding the component associated with AAAs) plus the 1-year aneurysm-related mortality without repair. The primary outcome for the study was 1-year mortality. Results: A total of 11 829 patients met study criteria. The median age was 84 years [81, 86] with 9014 (76.2%) being male. Maximal AAA diameters were apportioned as follows: 39.6% were <5.5 cm, 28.6% were 5.5–5.9 cm, 21.3% were 6.0–6.9 cm, and 10.6% were ≥7.0 cm. The predicted 1-year mortality rate without EVAR was 11.9%, which was significantly higher than the actual 1-year mortality rate with EVAR (8.2%; p<0.001). The overall rate of perioperative MACE was 4.4% (n = 516). Patients with an aneurysm diameter <5.5cm had worse actual 1-year mortality rates with EVAR compared to predicted 1-year mortality rates without EVAR. In contrast, those with larger aneurysms (≥5.5cm) had better actual 1-year mortality rates with EVAR. The benefit from EVAR for those with Gagne Indices 2–5 was largely restricted to those with AAAs ≥ 7.0cm; whereas those with Gagne Indices 0–1 experience a survival benefit for AAAs larger than 5.5 cm. Conclusion: The current data suggest that EVAR decreases 1-year mortality rates for patients of advanced age compared to non-operative management in the elderly. However, the survival benefit is largely limited to those with Gagne Indices 0–1 with AAAs ≥ 5.5 cm and Gagne Indices 2–5 with AAAs ≥ 7.0 cm. Those of advanced age may benefit from EVAR, but realizing this benefit requires careful patient selection.

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Mortality due to respiratory diseases in the elderly after influenza vaccination campaigns in the Federal District, Brazil, 1996-2009

Jornal Brasileiro de Pneumologia ◽

10.1590/s1806-37132013000200011 ◽

2013 ◽

Vol 39 (2) ◽

pp. 198-204 ◽

Cited By ~ 2

Author(s):

Francisca Magalhães Scoralick ◽

Luciana Paganini Piazzolla ◽

Liana Laura Pires ◽

Cleudsom Neri ◽

Wladimir Kummer de Paula

Keyword(s):

Mortality Rate ◽

Influenza Vaccination ◽

Respiratory Diseases ◽

Positive Impact ◽

Vaccination Campaign ◽

Age Groups ◽

Federal District ◽

The Elderly ◽

Analysis Data ◽

Proportional Mortality

OBJECTIVE: To compare mortality rates due to respiratory diseases among elderly individuals residing in the Federal District of Brasília, Brazil, prior to and after the implementation of a national influenza vaccination campaign. METHODS: This was an ecological time series analysis. Data regarding the population of individuals who were over 60 years of age between 1996 and 2009 were obtained from official databases. The variables of interest were the crude mortality rate (CMR), the mortality rate due to the respiratory disease (MRRD), and the proportional mortality ratio (PMR) for respiratory diseases. We performed a qualitative analysis of the data for the period prior to and after the implementation of the vaccination campaign (1996-1999 and 2000-2009, respectively). RESULTS: The CMR increased with advancing age. Over the course of the study period, we observed reductions in the CMR in all of the age brackets studied, particularly among those aged 80 years or older. Reductions in the MRRD were also found in all of the age groups, especially in those aged 80 years or older. In addition, there was a decrease in the PMR for respiratory diseases in all age groups throughout the study period. The most pronounced decrease in the PMR for respiratory diseases in the ≥ 70 year age bracket occurred in 2000 (immediately following the implementation of the national vaccination campaign); in 2001, that rate increased in all age groups, despite the greater adherence to the vaccination campaign in comparison with that recorded for 2000. CONCLUSIONS: Influenza vaccination appears to have a positive impact on the prevention of mortality due to respiratory diseases, particularly in the population aged 70 or over.

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Treatment of cyanotic heart diseases in children

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh04s1009j ◽

2004 ◽

Vol 132 (suppl. 1) ◽

pp. 9-13

Author(s):

Ida Jovanovic ◽

Vojislav Parezanovic ◽

Slobodan Ilic ◽

Djordje Hercog ◽

Milan Vucicevic ◽

...

Keyword(s):

Heart Disease ◽

Mortality Rate ◽

Surgical Procedures ◽

Heart Surgery ◽

Heart Diseases ◽

Arterial Switch Operation ◽

Open Heart Surgery ◽

Age Groups ◽

Mortality Rates ◽

Cyanotic Heart Disease

Cyanotic heart diseases are relatively rare, but they are severe and heterogeneous congenital heart diseases, which require complex surgery. Development of different advanced surgical procedures, such as arterial switch operation (ASO), Fontan and its modifications, Norwood etc. operations, as well as better perioperative care significantly improved survival rate and quality of life of these children. The study group included 308 children treated for cyanotic heart disease in Yugoslavia, in the period January 2000 to July 2004. Some of them (239, 77.6%) were treated at the University Children?s Hospital in Belgrade, and others (69, 22.4%) in different institutions abroad. The age of the operated patients varied between 1 day and 19 years (median 12 months). The patients (pts) were divided into four groups, according to the disease and type of the operation. In the whole group of 308 patients treated due to cyanotic heart disease, there were 232 (75.3%) cases with open heart surgery and 76 (24.7%) with closed procedures. The mortality rate was significantly different between disease/operation groups, and age groups. Average mortality rates differed from 11.8% for palliative procedures to 12.5% for complete corrections. Mortality rate and achieved surgical results in treatment of chil?dren with cyanotic heart diseases were significantly worse than those published by leading cardiac surgery centers in the world. However, there is a clear tendency in introducing new surgical procedures, lowering the age at which the operation is done and decreasing the mortality rates.

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Characteristics of mortality in the Orenburg region population in 2011-2017

Science and Innovations in Medicine ◽

10.35693/2500-1388-2020-5-2-99-104 ◽

2020 ◽

Vol 5 (2) ◽

pp. 99-104

Author(s):

Evgenii L. Borschuk ◽

Dmitrii N. Begun ◽

Tatyana V. Begun

Keyword(s):

Mortality Rate ◽

Causes Of Death ◽

Age Groups ◽

Circulatory System ◽

Mortality Rates ◽

Female Population ◽

Orenburg Region ◽

The Third ◽

Circulatory System Diseases ◽

External Causes

Objectives - to study the mortality indicators, their dynamics and structure, in the population of the Orenburg region in the period of 2011-2017. Material and methods. The study was conducted using the data from the territorial authority of statistics in the Orenburg region in the period from 2011 to 2017. The analytical, demographic and statistical methods were implemented for the study of the demographic indicators. Results. Cities and municipal settlements of the Orenburg region with high mortality indicators were included in the second and fourth clusters during the cluster analysis. The first and third clusters included cities and municipal settlements with an average mortality. The most favorable position has the Orenburg area with the lowest mortality rate in the region in 2017 - 8.4%. The dynamics of mortality rates among the male and female population tends to decrease, more pronounced dynamics is in men. Though, the male population is characterized by higher mortality rates in all age groups. The leading position among the causes of death is taken by diseases of the circulatory system (46.3% of the total mortality). The second position is occupied by tumors (17.2%), the third - by external causes (8.4%). Mortality from circulatory system diseases and from external causes has reduced. The dynamics of mortality from tumors does not change significantly. The rank of leading causes of death is not identical in the clusters: in the third and fourth clusters, the other causes occupy the second place in the structure of mortality, while tumors occupy the third. Conclusion. In the Orenburg region, the mortality rate is higher than overage in the Russian Federation by 0.9 per 1000 people. The study revealed significant territorial differences in the mortality rates. In general, the mortality among men in all age groups is higher than the mortality of women. The mortality rate from diseases of the circulatory system plays the leading role in the structure of mortality, but has the tendency for decline. Until 2006, the mortality from external causes ranked the second place, now the second place is taken by death from tumors The mortality from external causes is decreasing; mortality from tumors does not change significantly. The obtained results could be used by local authorities in developing the program of public health protection and assessing its effectiveness.

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Assessing Age-Specific Vaccination Strategies and Post-Vaccination Reopening Policies for COVID-19 Control Using SEIR Modeling Approach

10.1101/2021.02.18.21251981 ◽

2021 ◽

Author(s):

Xia Wang ◽

Hulin Wu ◽

Sanyi Tang

Keyword(s):

Age Structure ◽

Age Groups ◽

Social Contact ◽

The Elderly ◽

Vaccination Rate ◽

Social Contacts ◽

Post Vaccination ◽

Vaccination Strategies ◽

Contact Patterns ◽

Effect Of Age

AbstractBackgroundAs the availability of COVID-19 vaccines, it is badly needed to develop vaccination guidelines to prioritize the vaccination delivery in order to effectively stop COVID-19 epidemic and minimize the loss.MethodsWe evaluated the effect of age-specific vaccination strategies on the number of infections and deaths using an SEIR model, considering the age structure and social contact patterns for different age groups for each of different countries.ResultsIn general, the vaccination priority should be given to those younger people who are active in social contacts to minimize the number of infections; while the vaccination priority should be given to the elderly to minimize the number of deaths. But this principle may not always apply when the interaction of age structure and age-specific social contact patterns is complicated. Partially reopening schools, workplaces or households, the vaccination priority may need to be adjusted accordingly.ConclusionsPrematurely reopening social contacts could initiate a new outbreak or even a new pandemic out of control if the vaccination rate and the detection rate are not high enough. Our result suggests that it requires at least nine months of vaccination before fully reopening social contacts in order to avoid a new pandemic.

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Mortality of the population of the Komi Region at the end of the – XIX beginning of the XX century: age composition

Historical demography ◽

10.19110/2304-5922-2021-1-11-14 ◽

2021 ◽

Vol 1 ◽

pp. 11-14

Author(s):

D.V. Vishnyakova ◽

Keyword(s):

Mortality Rate ◽

Age Groups ◽

Mortality Rates ◽

Age Composition ◽

Younger Age ◽

Significant Concentration

The article describes some mortality rates of the population of the Komi Region in the late XIX-early XX century. The age composition of the deceased is revealed, with a distribution by gender. During the studied time, mortality was characterized by a significant concentration in younger age groups. The mortality rate of children under the age of five years averaged 55–70 % of the total number of deaths in the region.

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