scholarly journals Unitary Structure of Palindromes in DNA

2021 ◽  
Author(s):  
Mehmet Ali Tibatan ◽  
Mustafa Sarisaman

We investigate the quantum behavior encountered in palindromes within DNA structure. In particular we reveal the unitary structure of usual palindromic sequences found in genomic DNAs of all living organisms using the Schwinger approach. We clearly demonstrate the role played by palindromic configurations with special emphasis on physical symmetries in particular subsymmetries of unitary structure. We unveil the prominence of unitary structure in palindromic sequences in the sense that vitally significant information endowed within DNA could be transformed unchangeably in the process of transcription. We introduce a new symmetry relation namely purine-purine or pyrimidine-pyrimidine symmetries (p-symmetry) in addition to the already known symmetry relation of purine-pyrimidine symmetries (pp symmetry) given by Chargaff rule. Therefore important vital functions of a living organisms are protected by means of these symmetric features. It is understood that higher order palindromic sequences could be generated in terms of the basis of the highest prime numbers that make up the palindrome sequence number. We propose that violation of this unitary structure of palindromic sequences by means of our proposed symmetries leads to a mutation in DNA which could offer a new perspective in the scientific studies on the origin and cause of mutation.

2020 ◽  
Vol 9 (4) ◽  
pp. 40-43
Author(s):  
N. K. Yuldasheva ◽  
S. D. Gusakova ◽  
D. Kh. Nurullaeva ◽  
N. T. Farmanova ◽  
R. P. Zakirova ◽  
...  

Introduction. Lipids are a widespread group of biologically active substances in nature, making up the bulk of the organic substances of all living organisms. They accumulate in plants in seeds, as well as in fruits and perform a number of vital functions: they are the main components of cell membranes and the energy reserve for the body.Aim. Study of neutral lipids of sown oats (Avena sativa L.).Materials and methods. The objects of the study were fruits (grains) of oats of the sown variety "Tashkent 1," harvested in the Republic of Uzbekistan. Results and discussions. Neutral lipids of oat grains have been found to contain 13 fatty acids with a predominance of the sum of oleic, linolenic and linoleic acids. The total degree of unsaturation was almost 78%. Absorption bands characteristic of these substances were observed in the IR spectrum of MEGC.Conclusion. According to the results of the NL analysis, oat grains consisted of triacylglycerides and free LCDs, which were accompanied by hydrocarbons, phytosterols, triterpenoids and tocopherols.


Marine Drugs ◽  
2022 ◽  
Vol 20 (1) ◽  
pp. 54
Author(s):  
Joko Tri Wibowo ◽  
Matthias Y. Kellermann ◽  
Lars-Erik Petersen ◽  
Yustian R. Alfiansah ◽  
Colleen Lattyak ◽  
...  

Melanin is a widely distributed and striking dark-colored pigment produced by countless living organisms. Although a wide range of bioactivities have been recognized, there are still major constraints in using melanin for biotechnological applications such as its fragmentary known chemical structure and its insolubility in inorganic and organic solvents. In this study, a bacterial culture of Streptomyces cavourensis SV 21 produced two distinct forms of melanin: (1) a particulate, insoluble form as well as (2) a rarely observed water-soluble form. The here presented novel, acid-free purification protocol of purified particulate melanin (PPM) and purified dissolved melanin (PDM) represents the basis for an in-depth comparison of their physicochemical and biological properties, which were compared to the traditional acid-based precipitation of melanin (AM) and to a synthetic melanin standard (SM). Our data show that the differences in solubility between PDM and PPM in aqueous solutions may be a result of different adjoining cation species, since the soluble PDM polymer is largely composed of Mg2+ ions and the insoluble PPM is dominated by Ca2+ ions. Furthermore, AM shared most properties with SM, which is likely attributed to a similar, acid-based production protocol. The here presented gentler approach of purifying melanin facilitates a new perspective of an intact form of soluble and insoluble melanin that is less chemical altered and thus closer to its original biological form.


2019 ◽  
pp. 44-61
Author(s):  
Oleksandr Cherevchenko

The article deals with an attempt to characterize a smell in human knowledge, analyzed the points of view of different scientists concerning this problem, considered odor markers of the artistic text as components of united system of verbal and non verbal individual resources aimed at forming different types of subtext. The olfactory feeling occupies the special place in the vital functions of man. They arose up one of the first, next to taste, which provided the living organisms two basic functions: feed and reproduction. However, in the process of evolution, olfactory feelings experienced the biggest changes European poetry of the beginning of XX century is interesting in its aspiration to create a new poetical speech that is why the attention is adhered to odor instruments, when the smell became an expression of the esthetical subtext. Odor content of the poetical speech of the XX century is one of the most important tools of forming content deepness of the text meaning, disclosure of the palette of meanings. The research is based on the material of poetry of representatives of Silver age and Ukrainian neoclassicists. The research proves that the most dynamic is lexical system of the language which helps to show ethnic language map of the world in artistic text. It studies the evolution of an individual author’s nomination in the poetic creativity of M. Rylsky, M. Zerov, Y. Klen, M. Dray-Hmara, P. Fylypovych, A. Block, N. Gumilov, A. Akchmatova, V. Maiakovski, S. Jesenin, V. Chlebnikov, O. Mandelshtam, M. Zvietaieva, V. Briusov and others. The paper examines the semantic-derivative structure of innovations of odor lexems, classifies the most numerous lexical and semantic groups of new words for identifying smell, and defines typical signs of odorous lexemes that represent the specific national language and poetic view of the world. Materials of the research can be used in teaching such subjects as “Modern Ukrainian Literary Language (lexicology, phraseology, lexicography)”, “Stylistics and Culture of the Ukrainian Language”, “Rhetoric and Linguistic Analysis of Artistic Text”, as well as special courses on ethnolinguistics, linguopoetics; for writing chapters devoted to the study of trope units, in textbooks and manuals; in lexicographic practice when compiling dictionaries of the writer’s language.


Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1757 ◽  
Author(s):  
Szymon Kowalski ◽  
Dariusz Wyrzykowski ◽  
Iwona Inkielewicz-Stępniak

Discovering that metals are essential for the structure and function of biomolecules has given a completely new perspective on the role of metal ions in living organisms. Nowadays, the design and synthesis of new metal-based compounds, as well as metal ion binding components, for the treatment of human diseases is one of the main aims of bioinorganic chemistry. One of the areas in vanadium-based compound research is their potential anticancer activity. In this review, we summarize recent molecular and cellular mechanisms in the cytotoxic activity of many different synthetic vanadium complexes as well as inorganic salts. Such mechanisms shall include DNA binding, oxidative stress, cell cycle regulation and programed cell death. We focus mainly on cellular studies involving many type of cancer cell lines trying to highlight some new significant advances.


2004 ◽  
Vol 10 (3) ◽  
pp. 261-276 ◽  
Author(s):  
John Stewart ◽  
Antonio Coutinho

The fundamental concepts of autopoiesis, which emphasize the circular organization underlying both living organisms and cognition, have been criticized on the grounds that since they are conceived as a tight logical chain of definitions and implications, it is often not clear whether they are indeed a scientific theory or rather just a potential scientific vocabulary of doubtful utility to working scientists. This article presents the deployment of the concepts of autopoiesis in the field of immunology, a discipline where working biologists themselves spontaneously have long had recourse to “cognitive” metaphors: “recognition”; a “repertoire” of recognized molecular shapes; “learning” and “memory”; and, most striking of all, a “self versus non-self” distinction. It is shown that in immunology, the concepts of autopoiesis can be employed to generate clear novel hypotheses, models demonstrating these ideas, testable predictions, and novel therapeutic procedures. Epistemologically, it is shown that the self–non-self distinction, while quite real, is misleadingly named. When a real mechanism for generating this distinction is identified, it appears that the actual operational distinction is between (a) a sufficiently numerous set of initial antigens, present from the start of ontogeny, in conditions that allow for their participation in the construction of the system's organization and operation, and (b) single antigens that are first presented to the system after two successive phases of maturation. To call this a self–non-self distinction obscures the issue by presupposing what it ought to be the job of scientific investigation to explain.


Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 3027
Author(s):  
Viviana Scognamiglio ◽  
Maria Teresa Giardi ◽  
Daniele Zappi ◽  
Eleftherios Touloupakis ◽  
Amina Antonacci

Photosynthetic microorganisms are among the fundamental living organisms exploited for millennia in many industrial applications, including the food chain, thanks to their adaptable behavior and intrinsic proprieties. The great multipotency of these photoautotroph microorganisms has been described through their attitude to become biofarm for the production of value-added compounds to develop functional foods and personalized drugs. Furthermore, such biological systems demonstrated their potential for green energy production (e.g., biofuel and green nanomaterials). In particular, the exploitation of photoautotrophs represents a concrete biorefinery system toward sustainability, currently a highly sought-after concept at the industrial level and for the environmental protection. However, technical and economic issues have been highlighted in the literature, and in particular, challenges and limitations have been identified. In this context, a new perspective has been recently considered to offer solutions and advances for the biomanufacturing of photosynthetic materials: the co-culture of photoautotrophs and bacteria. The rational of this review is to describe the recently released information regarding this microbial consortium, analyzing the critical issues, the strengths and the next challenges to be faced for the intentions attainment.


Author(s):  
Carlo Brogna

Acetylcholine (ACh) is the best one characterized neurotransmitter. Its central roles in the cholinergic areas and central nervous system (CNS) and peripheral (PNS) synapses are well known. It was the first molecule identified as a neurotransmitter and appears to be phylogenetically the oldest one signaling molecules. ACh was detected in bacteria, protozoa, fungi, algae and primitive plants, indicating that the cholinergic system was widely distributed in living organisms before its appearance in the nervous system. The autonomous nervous system (ANS) is an integral part animal kingdom history. It determines fight-escape reactions as well as outlining the vital and cognitive functions bio-organization rhythms. The virus (Covid-19) extraneous effects acting on it could help to better understand its functions. The Blast results show some factors like protein that can be implicated such as bungaro-toxins, phospholipase A2 and the similar prothrombin activator protein. A positive correlation with different toxins is obtained and the Covid-19 double pathogenic mechanism theory is proposed. The process allows us to outline the possibility about toxic-like factors presence.


2019 ◽  
Vol 12 (1) ◽  
pp. 49-55
Author(s):  
Hamid Ali Abed Almousawi ◽  
Mustafa Kamil Kadhim

The biotic balance is a special strategy followed by the building, which helps it to stay and interact, and perform vital functions at a constant and natural rate under suitable conditions or the possibility of making them suitable, in the light of the general trend that seeks to preserve nature, as a result of the emergence of concepts of sustainability and green architecture and applied models of polarization outside the environment Which resulted in buildings that are not compatible with the environment and thus reduced environmental performance of the building, emerged the research problem of "lack of knowledge about the mechanisms of living organisms to achieve a biological balance with the surrounding nature." The main objective of the research was to "build a cognitive perception about the mechanisms by which living organisms create a biological balance with the surrounding environment." Therefore, the main research hypothesis was that there is a similarity between the mechanisms used by living organisms to balance the surrounding nature and the architectural solutions that the architect must follow to achieve the same Harmony with the surrounding nature, "and therefore adopted the methodology of research on two parts: First: the theoretical study, which includes the introduction of concepts and considerations related to the concept of biological balance, and knowledge of the mechanisms used by living organisms and try to apply in the field of architecture, The study concluded that the strategies of living organisms in dealing with the surrounding environment, along with the automatic architecture of marsh homes, is the basis of the main hypothesis and its applicability.


Molecules ◽  
2020 ◽  
Vol 25 (16) ◽  
pp. 3607
Author(s):  
Barbara Demmig-Adams ◽  
Marina López-Pozo ◽  
Jared J. Stewart ◽  
William W. Adams

This review compares and contrasts the role of carotenoids across the taxa of life—with a focus on the xanthophyll zeaxanthin (and its structural isomer lutein) in plants and humans. Xanthophylls’ multiple protective roles are summarized, with attention to the similarities and differences in the roles of zeaxanthin and lutein in plants versus animals, as well as the role of meso-zeaxanthin in humans. Detail is provided on the unique control of zeaxanthin function in photosynthesis, that results in its limited availability in leafy vegetables and the human diet. The question of an optimal dietary antioxidant supply is evaluated in the context of the dual roles of both oxidants and antioxidants, in all vital functions of living organisms, and the profound impact of individual and environmental context.


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