scholarly journals Suppression of fibrillation consisting of stable rotors by periodic pacing

2021 ◽  
Author(s):  
Pavel Buran ◽  
Thomas Niedermayer ◽  
Markus Bär
Keyword(s):  
Cardiac Tissue ◽  
Success Probability ◽  
Experimental Studies ◽  
High Energy ◽  
Spatiotemporal Chaos ◽  
Low Energy ◽  
Strongly Correlated ◽  
Electrical Field Strength ◽  
Excitable Tissue ◽  
Dominant Period

Recent experimental studies have shown that a sequence of low-energy electrical far-field pulses is able to terminate fibrillation with substantially lower per-pulse energy than a single high-energy electric shock (see S. Luther et al. Nature 475 (7355), 235-239). During this low-energy antifibrillation pacing (LEAP) procedure only tissue near sufficiently large conduction heterogeneities, such as large coronary arteries, is activated. In order to understand the mechanism behind LEAP, We have carried out a statistical study of resetting a medium filled by one or more stable spirals (“rotors”) in a two-dimensional electrophysiological model of cardiac tissue perforated by blood vessels to the resting state (“defibrillation”). We found the highest success probabilities for this defibrillation for underdrive pacing with periods 10 – 20 percent larger than the dominant period of the stable rotors in the unperturbed dynamics. If a sufficiently large number pulses is applied and an optimal pacing period chosen, the energy per pulse required for successful defibrillation is about 75 - 80 percent lower than the energy needed for single-shock defibrillation. Optimal conditions to control and suppress fibrillation based on stable rotors, hence, are similar to the ones in found for the case of an electrophysiological model displaying spatiotemporal chaos (“electrical turbulence”) in an earlier study (see P. Buran et al. Chaos 27, 113110 (2017)). The optimal pacing period is found to increase with increasing strength of the electrical field strength used in the model. The success probability also increases strongly until the fourth or fifth pulse administered, which is strongly correlated to an observed increase of the fraction of re-excitable tissue with each subsequent pulse. Monitoring the fraction of excitable tissue in the model as key quantity of the excitable medium, moreover, enabled us to successfully predict the optimal pacing period for defibrillation.

Assessment of the volume activity of α-radioactive wastes on surface and specific contamination by portable γ-spectrometry method

2020 ◽  
pp. 468-473
Author(s):  
I. P. Korenkov ◽  
A. I. Ermakov ◽  
A. B. Mayzik ◽  
T. N. Laschenova ◽  
V. N. Klochkov ◽  
...  
Keyword(s):  
Specific Activity ◽  
Experimental Studies ◽  
Germanium Detector ◽  
Low Energy ◽  
Gamma Ray Spectrometry ◽  
Building Structures ◽  
Germanium Detectors ◽  
Volume Activity ◽  
Β Decay ◽  
Γ Spectrometry

The aim of the study is to evaluate the volume activity of radioactive waste (RW) by surface and specific alpha contamination using portable gamma-spectrometry.Materials and methods. Methods of rapid assessment of the content of α-emitting radionuclides in solid waste of various morphologies using gamma-spectrometers based on germanium detectors are considered. Computational methods for determining the effectiveness of radionuclide registration are presented.Results. The possibility of using portable gamma-ray spectrometry to assess the surface and specific activity of various materials contaminated with α-emitters (232Th, 235U, 238U, 237Np, 239Pu, 240Pu and 241Am) is shown. The calculated values of the registration efficiency of low-energy gamma-emitters obtained by modeling the spatial-energy parameters of the detector are given.To simplify the solution of this problem, the calculation program used 20 standard templates of various geometries (rectangular, cylindrical, conical, spherical, etc.). The main sources of error in the survey of contaminated surfaces, largesized equipment and building structures were investigated.Conclusions. The possibilities of portable γ-spectrometry for estimating the volume of RW based on the surface density of contamination of materials with radionuclides of uranium and transuranic elements are investigated. When using γ-spectrometer with a high-purity germanium detector with a range of γ-quanta extended in the low-energy region, radionuclides such as 232Th, 235U,238U, 237Np, 241Am were determined by their own radiation or by the radiation of their daughter products.The “problem” element is plutonium, for rapid evaluation of which it is proposed, in accordance with the radionuclide vector methodology, to use 241Am, which accumulates during the β-decay of 241Pu.According to calculations, the most likely value of the activity ratio 239Pu/241Am for the object where the work was performed (scaling factor) varies in the range from 5.0 to 9.0.Based on the results of calculations and experimental studies, the parameters of the efficiency of registration of various α-emitting radionuclides by portable γ-spectrometers. It has been found that for germanium detectors with an absolute efficiency of registering a point source of 7÷15%, it is n×10–5÷n×10–4%.

Low energy vs. high energy depositional settings and related sedimentary bodies in early Senenian rudist bearing carbonate shelves (central-southern Italy)

2001 ◽  
Vol 28 (1) ◽  
pp. 37-40 ◽  
Author(s):  
Gabriele Carannante ◽  
A. Laviano ◽  
D. Ruberti ◽  
Lucia Simone ◽  
G. Sirna ◽  
...  
Keyword(s):  
Southern Italy ◽  
High Energy ◽  
Low Energy ◽  
Depositional Settings

Transportation: Fuel Energies

2017 ◽  
Author(s):  
Peter Rez
Keyword(s):  
Energy Density ◽  
Fossil Fuels ◽  
High Energy ◽  
Ease Of Use ◽  
Low Energy ◽  
High Energy Density ◽  
Nuclear Fuels ◽  
Liquid Hydrocarbons ◽  
Transportation Fuel ◽  
Journey Time

Transportation efficiency can be measured in terms of the energy needed to move a person or a tonne of freight over a given distance. For passengers, journey time is important, so an equally useful measure is the product of the energy used and the time taken for the journey. Transportation requires storage of energy. Rechargeable systems such as batteries have very low energy densities as compared to fossil fuels. The highest energy densities come from nuclear fuels, although, because of shielding requirements, these are not practical for most forms of transportation. Liquid hydrocarbons represent a nice compromise between high energy density and ease of use.

scholarly journals Low-Energy Electron Damage to Condensed-Phase DNA and Its Constituents

2021 ◽  
Vol 22 (15) ◽  
pp. 7879
Author(s):  
Yingxia Gao ◽  
Yi Zheng ◽  
Léon Sanche
Keyword(s):  
Condensed Phase ◽  
Genetic Material ◽  
High Energy ◽  
Dna Lesions ◽  
Low Energy ◽  
Experimental Investigations ◽  
Experimental Conditions ◽  
Strand Breaks ◽  
Sequence Of Events ◽  
Wide Range

The complex physical and chemical reactions between the large number of low-energy (0–30 eV) electrons (LEEs) released by high energy radiation interacting with genetic material can lead to the formation of various DNA lesions such as crosslinks, single strand breaks, base modifications, and cleavage, as well as double strand breaks and other cluster damages. When crosslinks and cluster damages cannot be repaired by the cell, they can cause genetic loss of information, mutations, apoptosis, and promote genomic instability. Through the efforts of many research groups in the past two decades, the study of the interaction between LEEs and DNA under different experimental conditions has unveiled some of the main mechanisms responsible for these damages. In the present review, we focus on experimental investigations in the condensed phase that range from fundamental DNA constituents to oligonucleotides, synthetic duplex DNA, and bacterial (i.e., plasmid) DNA. These targets were irradiated either with LEEs from a monoenergetic-electron or photoelectron source, as sub-monolayer, monolayer, or multilayer films and within clusters or water solutions. Each type of experiment is briefly described, and the observed DNA damages are reported, along with the proposed mechanisms. Defining the role of LEEs within the sequence of events leading to radiobiological lesions contributes to our understanding of the action of radiation on living organisms, over a wide range of initial radiation energies. Applications of the interaction of LEEs with DNA to radiotherapy are briefly summarized.

Fabrication of the narrow size nano curcuminoids emulsion by combining phase inversion temperature and ultrasonication: preparation and bioactivity

2021 ◽  
Author(s):  
Quang Hieu Tran ◽  
Thuy Thanh Ho ◽  
Tu Thanh Nguyen
Keyword(s):  
Energy Method ◽  
Phase Inversion ◽  
Curcuma Longa ◽  
High Energy ◽  
Low Energy ◽  
Inversion Temperature ◽  
Comprehensive Study ◽  
Phase Inversion Temperature

A comprehensive study from Curcuma longa to powder nano curcuminoids has been carried out. Combining of both low energy method (Phase Inversion Temperature) and high-energy method (Ultrasonication), a series of...

scholarly journals Charge transport through extended molecular wires with strongly correlated electrons

2021 ◽  
Author(s):  
James O. Thomas ◽  
Jakub K. Sowa ◽  
Bart Limburg ◽  
Xinya Bian ◽  
Charalambos Evangeli ◽  
...  
Keyword(s):  
Electron Transport ◽  
Charge Transport ◽  
Experimental Studies ◽  
Strongly Correlated Electrons ◽  
Molecular Wires ◽  
Correlated Electrons ◽  
Strongly Correlated

Experimental studies of electron transport through an edge-fused porphyrin oligomer in a graphene junction are interpreted within a Hubbard dimer framework.

scholarly journals The low-energy effective theory of axions and ALPs

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Martin Bauer ◽  
Matthias Neubert ◽  
Sophie Renner ◽  
Marvin Schnubel ◽  
Andrea Thamm
Keyword(s):  
High Energy ◽  
New Physics ◽  
Mass Scale ◽  
Low Energy ◽  
Effective Theory ◽  
Loop Order ◽  
Flavor Changing ◽  
Effective Lagrangian ◽  
Anomalous Dimensions ◽  
Pseudoscalar Mesons

Abstract Axions and axion-like particles (ALPs) are well-motivated low-energy relics of high-energy extensions of the Standard Model, which interact with the known particles through higher-dimensional operators suppressed by the mass scale Λ of the new-physics sector. Starting from the most general dimension-5 interactions, we discuss in detail the evolution of the ALP couplings from the new-physics scale to energies at and below the scale of electroweak symmetry breaking. We derive the relevant anomalous dimensions at two-loop order in gauge couplings and one-loop order in Yukawa interactions, carefully considering the treatment of a redundant operator involving an ALP coupling to the Higgs current. We account for one-loop (and partially two-loop) matching contributions at the weak scale, including in particular flavor-changing effects. The relations between different equivalent forms of the effective Lagrangian are discussed in detail. We also construct the effective chiral Lagrangian for an ALP interacting with photons and light pseudoscalar mesons, pointing out important differences with the corresponding Lagrangian for the QCD axion.

scholarly journals Combination of Dual-Energy X-ray Transmission and Variable Gas-Ejection for the In-Line Automatic Sorting of Many Types of Scrap in One Measurement

2021 ◽  
Vol 11 (10) ◽  
pp. 4349
Author(s):  
Tianzhong Xiong ◽  
Wenhua Ye ◽  
Xiang Xu
Keyword(s):  
High Efficiency ◽  
Nearest Neighbor ◽  
High Energy ◽  
Dual Energy ◽  
Center Of Gravity ◽  
Low Energy ◽  
Identification Accuracy ◽  
Flow Process ◽  
X Ray ◽  
Automatic Sorting

As an important part of pretreatment before recycling, sorting has a great impact on the quality, efficiency, cost and difficulty of recycling. In this paper, dual-energy X-ray transmission (DE-XRT) combined with variable gas-ejection is used to improve the quality and efficiency of in-line automatic sorting of waste non-ferrous metals. A method was proposed to judge the sorting ability, identify the types, and calculate the mass and center-of-gravity coordinates according to the shading of low-energy, the line scan direction coordinate and transparency natural logarithm ratio of low energy to high energy (R_value). The material identification was satisfied by the nearest neighbor algorithm of effective points in the material range to the R_value calibration surface. The flow-process of identification was also presented. Based on the thickness of the calibration surface, the material mass and center-of-gravity coordinates were calculated. The feasibility of controlling material falling points by variable gas-ejection was analyzed. The experimental verification of self-made materials showed that identification accuracy by count basis was 85%, mass and center-of-gravity coordinates calculation errors were both below 5%. The method proposed features high accuracy, high efficiency, and low operation cost and is of great application value even to other solid waste sorting, such as plastics, glass and ceramics.

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