Evaluation of manubriosternal joint fusion and second costal cartilage calcification: Are they useful for estimating advanced age groups?

2021 ◽  
Author(s):  
Cemil Oktay ◽  
Güneş Aytaç
Keyword(s):  
Costal Cartilage ◽  
Age Groups ◽  
Advanced Age ◽  
Cartilage Calcification ◽  
Joint Fusion ◽  
Manubriosternal Joint

scholarly journals Trends in prevalence of gestational diabetes mellitus in Zhejiang Province, China, 2016–2018

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Meng Wang ◽  
Ru-Ying Hu ◽  
Wei-Wei Gong ◽  
Jin Pan ◽  
Fang-Rong Fei ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Rural Areas ◽  
Urban Areas ◽  
Age Groups ◽  
Zhejiang Province ◽  
Advanced Age ◽  
Female Population ◽  
Annual Prevalence

Abstract Background Limited population-based studies have investigated the secular trend of prevalence of gestational diabetes mellitus (GDM) in mainland China. Therefore, this study aimed to estimate the prevalence of GDM and time trends in Chinese female population. Methods Based on Diabetes Surveillance System of Zhejiang Province, 97,063 diagnosed GDM cases aged 20–50 years were identified from January 1, 2016 to December 31, 2018. Annual prevalence, prevalence rate ratios (PRRs) and average annual percentage change with their 95% confidence intervals (CIs) were reported. Results The age-standardized overall prevalence of GDM was reported to be 7.30% (95% CI 7.27–7.33%); 9.13% (95% CI 9.07–9.19%) in urban areas and 6.24% (95% CI 6.21–6.27%) in rural areas. Compared with 20–24 years age group, women in advanced age groups (25–50 years) were at higher risk for GDM (PRRs ranged from 1.37 to 8.95 and the 95% CIs did not include the null). Compared with rural areas, the risk for GDM was higher in urban areas (PRR: 1.69, 95% CI 1.67–1.72). The standardized annual prevalence increased from 6.02% in 2016 to 7.94% in 2018, with an average annual increase of 5.48%, and grew more rapidly in rural than urban areas (11.28% vs. 0.00%). Conclusions This study suggested a significant increase in the prevalence of GDM among Chinese female population in Zhejiang province during 2016–2018, especially in women characterized by advanced age and rural areas.

654 PHARYNGEAL POUCH SURGERY IN OCTO- AND NONAGENARIANS IS SAFE AND EFFECTIVE: A MULTICENTER COMPARATIVE COHORT STUDY

2021 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
David Liu ◽  
Mohamed Afzal ◽  
Tim Bright ◽  
David Watson ◽  
Peter Devitt ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Revisional Surgery ◽  
Age Groups ◽  
Symptomatic Improvement ◽  
Advanced Age ◽  
Perioperative Outcomes ◽  
Pharyngeal Pouch ◽  
Comparative Cohort Study ◽  
Pouch Surgery

Abstract   Surgery is the only effective treatment strategy for a symptomatic pharyngeal pouch. However, octo- and nonagenarians are often denied referral to a surgeon because of perceived increased risks. Here, we examine the perioperative outcomes of pharyngeal pouch surgery in octo- and nonagenarians in comparison to patients under 80 years-of-age. Methods Analysis of a prospectively maintained database of 113 patients (≥80 years-of-age: 27, <80 years-of-age: 86) who underwent pharyngeal pouch surgery across seven hospitals from 1 January 2006 to 30 September 2020. Results Patients ≥80 years-of-age had comparable operative time, complication profile, intensive care admission, emergency reoperation, and revisional surgery as their younger counterparts. The severity of complications was not significantly different between the two age groups. No surgical mortality was recorded. Multivariate analysis demonstrated that diverticulectomy combined with cricopharyngeal myotomy independently predicted higher rates of complications (OR: 4.53, 95% CI: 1.43-14.33, p = 0.010), but also greater symptomatic improvement (OR: 4.36, 95% CI: 1.50-12.67, p = 0.007). Importantly, a greater proportion of octo- and nonagenarians experienced improved swallowing than patients <80 years-of-age (96.3% vs. 74.4%, p = 0.013). Advanced age was not predictive of complications on multivariate analysis. Conclusion In appropriately selected patients, pharyngeal pouch surgery can be safely offered to patients above 80 years-of-age resulting in significant improvement in their quality-of-life. These patients should not be denied surgery on the basis of advanced age alone.

Adjuvant chemotherapy (AC) initiation and early discontinuation in elderly patients (EPs) with stage III colon cancer (CC).

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 6014-6014
Author(s):  
Jenny J Ko ◽  
Hagen F. Kennecke ◽  
Howard John Lim ◽  
Sharlene Gill ◽  
Ryan Woods ◽  
...  
Keyword(s):  
Age Groups ◽  
Young Patients ◽  
Advanced Age ◽  
Stage Iii ◽  
Early Discontinuation ◽  
Cancer Specific Survival ◽  
Entire Cohort ◽  
Stage Iii Colon Cancer ◽  
The Impact ◽  
To Receive

6014 Background: Research suggests that EPs with cancer are commonly undertreated, but the precise reasons for this observation are unclear. Our aims were to 1) evaluate the impact of advanced age on AC use (none vs capecitabine vs FOLFOX) for stage III CC, 2) determine the specific reasons for selecting and discontinuing a particular regimen, and 3) examine if the effect of AC on outcomes is modified by age. Methods: Patients diagnosed with stage III CC from 2006 to 2008 and referred to any 1 of 5 cancer centers in British Columbia, Canada were identified. Descriptive statistics were used to summarize treatment patterns in young patients (YPs) aged <70 vs EPs aged >/=70 years. Logistic regression was used to evaluate the association between AC and cancer-specific survival (CSS) in YPs and EPs. Results: We identified 810 patients: 51% men, 52% YPs and 48% EPs, and 74% received AC in the entire cohort. When compared to YPs, EPs had worse ECOG and more comorbidities (both p<0.01). EPs were less likely than YPs to receive AC (57 vs 91%, p<0.01). Frequent reasons for no treatment included age, comorbidities and perceived minimal benefit from AC. Among those treated with AC, EPs were less likely to receive FOLFOX (32 vs 74%, p<0.01) in favor of capecitabine due to patient preference, age and comorbidities. Once started on AC, EPs had similar rates of early treatment discontinuation as YPs (70 vs 62%, p=0.08). Reasons for early discontinuation were comparable between EPs and YPs (Table). Receipt of either FOLFOX or capecitabine was correlated with improved CSS, compared to surgery alone. Age did not modify CSS, irrespective of AC choice (interaction p for capecitabine and age=0.26; interaction p for FOLFOX and age=0.40). Conclusions: EPs with stage III CC frequently received either no adjuvant treatment or capecitabine monotherapy due to advanced age and comorbidities. The treatment effect of AC on CSS is similar across age groups, with comparable side effects and rates of discontinuation between EPs and YPs. AC should not be withheld from CC patients based on advanced age alone. [Table: see text]

Breast lump

2015 ◽  
Author(s):  
Hugo Farne ◽  
Edward Norris-Cervetto ◽  
James Warbrick-Smith
Keyword(s):  
Breast Cancer ◽  
Breast Feeding ◽  
Costal Cartilage ◽  
Age Groups ◽  
Develop Breast Cancer ◽  
Abscess Formation ◽  
Cystic Change ◽  
Breast Lump ◽  
Breast Lumps ◽  
Periductal Mastitis

The four most common diagnoses for a breast lump are: • Benign cystic change (also known as fibrocystic change, fibroadenosis, or benign breast change) • Fibroadenoma • Cyst • Carcinoma If we consider women of all ages, there are a number of other potential diagnoses: • Fat necrosis • Periductal mastitis • Abscess • Galactocele • Phyllodes tumour • Sarcoma • Duct papilloma • ‘Non-breast’ lumps, e.g. lipoma, sebaceous cyst, prominent costal cartilage/rib. The age of the patient is one of the most useful pieces of information for narrowing the differential. As an approximate guide, the most common diagnoses in the following age groups are: • <30 years: physiologically normal lumpy breast; benign cystic change; fibroadenoma; abscess (if breast-feeding); galactocele (if breast-feeding) • 30–45 years: benign cystic change; cyst; abscess (especially smokers); carcinoma • 45–60 years: cyst; abscess (smokers); carcinoma • >60 years: carcinoma ▲ Note: It is worth emphasizing that breast cancer is possible in all ages, is common, and is potentially very serious. Therefore you must exclude it in any presentation of breast lump, regardless of how benign it seems. Failure to diagnose breast cancer is one of the most common malpractice claims in the USA. Galactoceles may occur during or shortly after the cessation of lactation. They may present as a firm mass (often subareolar) and are caused by the obstruction of a lactiferous duct. The duct gradually becomes more distended with milk and epithelial cells, and may rarely be complicated by a secondary infection leading to abscess formation. Clinically, a galactocele is very similar to a cyst on examination. In addition, lactating women are predisposed to mastitis (whether or not they have a galactocele). The causative organisms are usually skin commensals such as Staphylococcus aureus or Staphylococcus epidermidis—this is in contrast to the periductal mastitis and abscess formation seen in older women, in whom anaerobic bacteria may also be implicated. Two of the greatest risk factors for breast cancer are being female and increasing age. Otherwise, the following are recognized as important factors: • Previous breast cancer • Family history of breast cancer. Suspicions should be raised if: ■ Three close blood relatives (on the same side of the family) develop breast cancer at any age

Total Knee Arthroplasty in Patients of Advanced Age: A Look at Outcomes and Complications

2018 ◽  
Vol 33 (01) ◽  
pp. 001-007 ◽  
Author(s):  
Peter G. Passias ◽  
Olivia J. Bono ◽  
James V. Bono
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Functional Outcomes ◽  
Older Patients ◽  
Age Groups ◽  
Review Article ◽  
Advanced Age ◽  
Complication Rates ◽  
Reconstructive Procedures ◽  
Total Knee

AbstractTotal knee arthroplasty (TKA) is one of the most highly successful orthopaedic procedures performed in North America. It is also one of the most common procedures performed, and its incidence continues to increase. Despite this, it is the opinion of many that patients of advanced age groups are not ideal candidates to undergo such procedures secondary to the concern over higher complication rates and poorer functional outcomes. This review article attempts to analyze the current body of literature concerning TKA outcomes and to evaluate some of the issues that are more specific to this population when they undergo TKA. It is our hypothesis that the literature does not support this popular misconception, and that older patients who do not have significant medical comorbidities are good candidates to undergo primary TKA. However, certain cohorts of this population are not ideal candidates to undergo this procedure. Also, certain joint reconstructive procedures, such as simultaneous and staged bilateral TKA, are higher risk procedures in this patient cohort.

Advanced age is not a barrier to creating a functional arteriovenous fistula: a retrospective study

2017 ◽  
Vol 18 (4) ◽  
pp. 307-312 ◽  
Author(s):  
Monica C. Beaulieu ◽  
Chance S. Dumaine ◽  
Alexandra Romann ◽  
Mercedeh Kiaii
Keyword(s):  
Cardiovascular Disease ◽  
Independent Risk Factor ◽  
Age Groups ◽  
Primary Patency ◽  
Advanced Age ◽  
Secondary Patency ◽  
Single Center ◽  
Younger Patients ◽  
Arteriovenous Fistulas ◽  
The Impact

Introduction Arteriovenous fistulas (AVFs) are the recommended form of vascular access for hemodialysis. However, controversy exists regarding whether AVFs are suitable for elderly patients. Methods Single-center retrospective review to investigate the impact of age on AVF outcomes. Five hundred and twenty-five patients with AVF creation were stratified based on age <65, 65-75, and >75 years. AVF outcomes including primary failure, AVF patency (primary, secondary, and functional), and AVF complications were studied for 3 years following AVF creation. Results The cohort was 63% male, 44% Caucasian, and 55% had diabetes or cardiovascular disease. 39% were aged <65 years, 33% 65-75 years, and 28% were aged >75 years. No differences in rates of primary failure, loss of primary patency, complications, or need for intervention were observed between age groups. There was a significant association of age with secondary patency and functional patency, with age >75 being an independent risk factor for shortened lifespan of the fistula. For patients aged >75 years, secondary patency at 3 years was 64% compared to 75%-78% for younger patients. Functional patency at 2 years was 69% for those aged >75 years compared to 78%-81% for younger patients. Conclusions We found no difference in AVF maturation, primary patency, complications, or interventions in those over the age of 75 compared to younger counterparts. While secondary and functional patency rates were significantly lower in those aged >75 years, the magnitude of difference is likely not clinically relevant. Therefore, we recommend that advanced age alone should not preclude patients from AVF creation.

scholarly journals Effect of Long-term Ingestion of Chicken Extract on Muscular Power for Middle and Advanced Age Groups

2012 ◽  
Vol 59 (4) ◽  
pp. 182-185 ◽  
Author(s):  
Mikako Sato ◽  
Hirohiko Maemura ◽  
Yoshihisa Takahata ◽  
Fumiki Morimatsu ◽  
Yuji Sato
Keyword(s):  
Age Groups ◽  
Advanced Age ◽  
Muscular Power

Costal Cartilage Calcification Presenting a Doughnut Appearance on 99mTc-Pyrophosphate Myocardial Imaging

1979 ◽  
Vol 4 (2) ◽  
pp. 83 ◽  
Author(s):  
F L DATZ ◽  
W R GRAY ◽  
S E LEWIS ◽  
J T WILLERSON ◽  
R W PARKEY
Keyword(s):  
Costal Cartilage ◽  
Myocardial Imaging ◽  
Cartilage Calcification

scholarly journals PREVALENCE OF MULTI-FOCAL ATHEROSCLEROTIC PATHOLOGY ACROSS AGE GROUPS

2013 ◽  
Vol 12 (2) ◽  
pp. 63-69
Author(s):  
A. N. Sumin ◽  
R. A. Gaifullin ◽  
A. V. Bezdenezhnykh ◽  
E. V. Korok ◽  
A. V. Karpovich ◽  
...  
Keyword(s):  
Cardiovascular Surgery ◽  
Age Groups ◽  
Intima Media Thickness ◽  
Group Iv ◽  
Advanced Age ◽  
Peripheral Angiography ◽  
Group Iii ◽  
Group I ◽  
High Prevalence ◽  
Group Ii

Aim. To compare the prevalence of multi-focal subclinical atherosclerotic pathology and its determinants in cardiovascular surgery patients.Material and methods. The study included 1018 patients — 825 en and 193 women (mean age 59,0±12,0 years) — who were hospitalised for a planned intervention on coronary or other arteries. Group I (n=542) was aged under 60 years, Group II (n=215) — 60–64 years, Group III (n=141) — 65–69 years, and Group IV (n=120) — 70 years or older. All participants underwent coronary angiography and Doppler ultrasound; peripheral angiography was performed, if necessary. Multi-focal atherosclerosis (MFA) criteria were the presence of stenosis (≥30%) or revascularisation in two or more vascular territories.Results. Subclinical atherosclerotic pathology of various localisation was observed in 52,3% of the patients. Advanced age was linked to an increase in the MFA prevalence: from 45,8% in Group I to 58,6% in Group II, 58,2% in Group III, and 63,3% in Group IV (p=0,0001). In Group I, MFA was associated with the intermittent claudication syndrome (ICS), decreased body mass index (BMI), increased intima-media thickness (IMT), elevated total cholesterol (TCH). However, in Groups II–IV, the only association observed was between MFA and ICS.Conclusion. Taking into account the subclinical (hemodynamically insignificant) arterial pathology had resulted in a high prevalence of MFA. Advanced age was associated with a higher MFA prevalence. Other factors linked to MFA were increased IMT, elevated TCH, decreased BMI, and ICS. 

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