Venous thrombosis in the elderly: incidence, risk factors and risk groups

2010 ◽  
Vol 8 (10) ◽  
pp. 2105-2112 ◽  
Author(s):  
M. J. ENGBERS ◽  
A. VAN HYLCKAMA VLIEG ◽  
F. R. ROSENDAAL
2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Jinzeng Zuo ◽  
Yongcheng Hu

Abstract Objective The purpose of this study was to investigate the incidence, location, and related factors of deep venous thrombosis (DVT) of the bilateral lower extremities after intertrochanteric fractures in the elderly. Methods Retrospective analysis was performed on the elderly patients with intertrochanteric fracture who were admitted from January 2017 to December 2019. At admission, patients receive routine ultrasound Doppler scanning of bilateral lower extremities to detect DVT; those with DVT were assigned to the case group and those without DVT to the control group. Patient data on demographics, comorbidities, injury-related data, and laboratory test results at admission were extracted. Logistic regression analyses were conducted to identify the independent risk factors associated with DVT. Results Five hundred seventy-eight patients were included, among whom 116 (20.1%) had DVT. Among those with DV, 70.7% (82/116) had DVT of the distal type, 24 (29.6%) had DVT of the proximal type, and 10 (10.4%) had mixed DVT. In 76.7% (89/116) of patients, DVT occurred in the fractured extremity, 9.5% (11/116) in the bilateral and 13.8% (16/116) in the non-fractured extremity. Multivariate analyses identified obesity, delay to admission, increased D-dimer level (> 1.44 mg/L) and reduced albumin (< 31.7 g/L) as independent factors. Conclusions Admission incidence of DVT was high in elderly patients with intertrochanteric fractures, especially the proximal DVT. Identification of associated risk factors is useful for individualized assessment risk of DVT and early targeted interventions.


2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Michele Manigrasso ◽  
Marco Milone ◽  
Nunzio Velotti ◽  
Sara Vertaldi ◽  
Pietro Schettino ◽  
...  

Abstract Background Although it is known that portomesenteric venous thrombosis (PMVT) is associated with total colectomy and proctocolectomy in young patients with inflammatory bowel disease, little is known about incidence and risk factors of PMVT among the elderly population undergoing colorectal surgery for cancer. Methods Data of elderly patients (> 70 years) undergoing surgery for colorectal cancer were retrospectively registered. The occurrence of PMVT was correlated with the patients’ characteristics and operative variables. Data collected included age, sex, obesity, ASA score, tumor degree, type of surgical resection, surgical approach (laparoscopic or open), and duration of surgery (from skin incision to the application of dressings). Results A total of 137 patients > 70 years who underwent surgery for colorectal cancer and developed an acute intraabdominal process with suggestive symptoms, needing a CT scan, were included. Three of these patients (2.1%) had portomesenteric venous thrombosis during the study period, which was proved with CT scan. There were no significant patients’ characteristics or operative variables between patients with or without the occurrence of PMVT after surgery. Of interest, only operative time was significantly higher in patients with PMVT after surgery (256 ± 40 vs 140 ± 41, p < 0.001). Conclusions PMVT as a cause of abdominal pain after colorectal surgery for cancer in the elderly population is uncommon. An index of suspicion for PMVT in an elderly postoperative colorectal cancer patient with sudden onset of abdominal pain must be maintained.


2016 ◽  
Vol 14 (9) ◽  
pp. 1759-1764 ◽  
Author(s):  
A. Karasu ◽  
M. J. Engbers ◽  
M. Cushman ◽  
F. R. Rosendaal ◽  
A. van Hylckama Vlieg

Author(s):  
Brunna Rodrigues de Lima ◽  
Brenda Kelly Gonçalves Nunes ◽  
Lara Cristina da Cunha Guimarães ◽  
Lucenda Fellipe de Almeida ◽  
Valéria Pagotto

ABSTRACT Objective: To identify the incidence, risk factors for delirium, and its association with death in the elderly hospitalized with fractures. Method: Prospective cohort, with a one-year follow-up of elderly people with clinical or radiological diagnosis of fracture, from an emergency and trauma hospital in the state of Goiás. The outcome delirium was defined by the medical description in the medical record. The predictor variables were demographic, health conditions, and hospitalization complications. A hierarchical multiple analysis was performed using robust Poisson regression, with Relative Risk as a measure of effect. Results: A total of 376 elderly patients were included. The incidence of delirium was 12.8% (n = 48). Risk factors were male gender, age ≥80 years, dementia, heart disease, osteoporosis, chronic obstructive pulmonary disease, high-energy traumas, pneumonia, urinary tract infection, and surgery. The risk of death in the sample was 1.97 times higher (HR: 1.97 95% CI 1.19–3.25) in elderly people with delirium. Conclusion: Delirium had an intermediate incidence (12.8%); the risk of death in this group was about 2 times higher in one year after hospital admission. Demographic factors, past history of diseases, surgery, and complications have increased the risk and require monitoring during hospitalization of elderly people with fractures.


2002 ◽  
Vol 95 (6) ◽  
pp. 290-292 ◽  
Author(s):  
Muhammad Asghar ◽  
Vedamurthy Adhiyaman ◽  
M W Greenway ◽  
Bhimal K Bhowmick ◽  
A Bates

Chronic subdural haematoma (CSDH) is predominantly a disease of the elderly. Most of the existing data come from studies done several decades ago. We examined the incidence, risk factors, clinical presentation, management and outcome in elderly patients with CSDH by retrospective study of the period 1996–1999 in the three district hospitals of North Wales. 40 cases of CSDH were identified in patients > 65 years, the incidence in this population being 8.2/100000. Falls (57%) and antithrombotic therapy (33%) were the most frequent risk factors. The most common presenting features were altered mental state (52%) and focal neurological deficit (50%). 24 patients (60%) underwent surgical intervention with 4 deaths (17%). In the non-operated group mortality was 7/16 (44%). Most of the deaths in this series were due either to CSDH or to the complications of frailty and poor mobility. Surgery itself was generally successful.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Sònia Jiménez ◽  
Òscar Miró ◽  
Pere Llorens ◽  
Francisco J. Martín-Sánchez ◽  
Guillermo Burillo-Putze ◽  
...  

2009 ◽  
Vol 14 (2) ◽  
Author(s):  
Anette Hylen Ranhoff

<span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><p align="left">I fjor sommer ble Europa rammet av en hetebølge og tusenvis av eldre mennesker døde. Sammenhengen mellom helsetilstand og påvirkning av klima er kompleks og medisinske, sosiale og miljømessige faktorer er involvert. Imidlertid er hete- og kulderelaterte sykdommer, skade og død i høy grad mulig å forebygge, og det er behov for å analysere denne situasjonen og andre ekstreme værsituasjoner for å kunne sikre helsen til eldre personer ved liknede hendelser i fremtiden.   Artikkelen gir en oversikt over litteratur som omhandler sykelighet og dødelighet som følge av ekstreme værforhold: hete, kulde og situasjoner der transport, elektrisitet og andre leveranser er begrenset, som etter en orkan, enorme snøfall eller liknende. Sammenhenger mellom sykelighet, dødelighet og temperatur i alminnelighet bli også omtalt, med spesielt fokus på de eldre.            </p><p align="left">Eldre som lever alene og er sosialt isolerte, og spesielt de som har funksjonshemning eller kognitiv svikt har høyest risiko for sykdom, skade og død i ekstreme værsituasjoner. Dette kan trolig i stor grad forebygges. Det anbefales at alle kommuner har kriseplaner for naturkatastrofer og ekstreme værsituasjoner som spesielt inneholder tiltak rettet mot sårbare eldre. Planene bør inneholde generell alarmering og informasjon samt systemer for oppsøkende virksomhet overfor risikogrupper.</p><p align="left"> </p><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><p>The 2003 heat wave in Europe was responsible for the deaths of thousands of elderly people. Heat- and cold-related illnesses, injuries and deaths are supposed to be largely preventable, and it is a need for analysing this situation and other situations with extreme weather conditions where elderly people are believed to be particularly vulnerable</p><p>This article is a review of the literature concerning morbidity and mortality in extreme weather conditions like heat, cold and situations where transportation, electricity, and other supplies are limited as a consequence of extreme weather such as after a hurricane or an enormous snowfall. Associations between mortality, morbidity and temperature in general are also discussed with focus on the elderly population<strong>. </strong>after a hurricane or an enormous snowfall. The frailest elderly are at the highest risk. In situati The elderly are at high risk for illnesses, injuries and death in extreme weather conditions. There are numerous reports from heat waves, but also cold-related problems are well documented. Other risk factors are disability, cognitive impairment, chronic disease, the use of special drugs and social isolation. Many risk factors are common for heat-, and cold-related problems, and also for other situations like<strong> </strong>ons with extreme weather conditions, we recommend local and central authorities to have emergency plans with special adaptations to the needs of elderly people and other vulnerable groups. These plans should include general warning and information and systems for preventive visits to high-risk groups.</p>. </span></span></span></span>


2001 ◽  
Vol 16 (4) ◽  
pp. 349-355 ◽  
Author(s):  
Patrizia Galanakis ◽  
Horst Bickel ◽  
Reiner Gradinger ◽  
Stephan Von Gumppenberg ◽  
Hans Förstl

Cancers ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 432
Author(s):  
Yu-Shin Hung ◽  
Jen-Shi Chen ◽  
Yen-Yang Chen ◽  
Chang-Hsien Lu ◽  
Pei-Hung Chang ◽  
...  

Background: Few studies have explored the association between pancreatic cancer and arterial thromboembolism (aTE). Methods: A total of 838 consecutive patients receiving palliative chemotherapy for pancreatic cancer between 2010 and 2016 were retrospectively enrolled. The clinical characteristics of patients were analyzed to determine the incidence, risk factors, and survival outcome of aTE in patients with pancreatic cancer. Results: aTE occurred in 42 (5.0%) of 838 patients. Patients with aTE had a worse survival outcome than those without (5.1 months versus 7.8 months, hazard ratio 1.53, 95% confidence interval [CI]: 1.12–2.09). Stage IV disease, high aspartate transaminase level, and comorbidity with hypertension or atrial fibrillation were four independent predictors of aTE. A concise predictive model stratified patients into low (0–1 predictor), intermediate (2 predictors), and high (3–4 predictors) risk groups. The hazard ratios for the comparison of patients in intermediate and high risk groups with those in low risk group were 4.55 (95% CI: 2.31–8.98), and 13.3 (95% CI: 5.63–31.6), respectively. Conclusion: Patients with pancreatic cancer undergoing palliative chemotherapy have an increased risk of aTE. A predictive model showed that patients presented with 3 or 4 predictors had the highest risk for developing aTE.


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