Heat Generation in Laser Irradiated Tissue

1989 ◽  
Vol 111 (1) ◽  
pp. 62-68 ◽  
Author(s):  
A. J. Welch ◽  
J. A. Pearce ◽  
K. R. Diller ◽  
G. Yoon ◽  
W. F. Cheong

Many medical applications involving lasers rely upon the generation of heat within the tissue for the desired therapeutic effect. Determination of the absorbed light energy in tissue is difficult in many cases. Although UV wavelengths of the excimer laser and 10.6 μm wavelength of the CO2 laser are absorbed within the first 20 μm of soft tissue, visible and near infrared wavelengths are scattered as well as absorbed. Typically, multiple scattering is a significant factor in the distribution of light in tissue and the resulting heat source term. An improved model is presented for estimating heat generation due to the absorption of a collimated (axisymmetric) laser beam and scattered light at each point r and z in tissue. Heat generated within tissue is a function of the laser power, the shape and size of the incident beam and the optical properties of the tissue at the irradiation wavelength. Key to the calculation of heat source strength is accurate estimation of the light distribution. Methods for experimentally determining the optical parameters of tissue are discussed in the context of the improved model.

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1018 ◽  
Author(s):  
Gloria Micó ◽  
Bernardo Gargallo ◽  
Daniel Pastor ◽  
Pascual Muñoz

In this paper the concept and design of an integrated optical device featuring evanescent field sensing and spectrometric analysis is presented. The device, termed integrated optics sensing spectrometer (IOSS), consists of a modified arrayed waveguide grating (AWG) which arms are engineered into two sets having different focal points. Half of the arms are exposed to the outer media, while the other half are left isolated, thus the device can provide both sensing and reference spectra. Two reference designs are provided for the visible and near-infrared wavelengths, aimed at the determination of the concentration of known solutes through absorption spectroscopy.


2019 ◽  
Vol 15 ◽  
pp. 2671-2677 ◽  
Author(s):  
Baptiste Amouroux ◽  
Clément Roux ◽  
Jean-Claude Micheau ◽  
Fabienne Gauffre ◽  
Christophe Coudret

Upconverting nanoparticles are a rising class of non-linear luminescent probes burgeoning since the beginning of the 2000’s, especially for their attractiveness in theranostics. However, the precise quantification of the light delivered remains a hot problem in order to estimate their impact on the biological medium. Sophisticated photophysical measurements under near infrared excitation have been developed only by few teams. Here, we present the first attempt towards a simple and cheap photochemical approach consisting of an actinometric characterization of the green emission of NaYF4:Yb,Er nanoparticles. Using the recently calibrated actinometer 1,2-bis(2,4-dimethyl-5-phenyl-3-thienyl)-3,3,4,4,5,5-hexafluoro-1-cyclopentene operating in the green region of the visible spectra, we propose a simple photochemical experiment to get an accurate estimation of the efficiency of these green-emitting “nanolamps”. The agreement of the collected data with the previous published results validates this approach.


2004 ◽  
Vol 32 (5) ◽  
pp. 489-505 ◽  
Author(s):  
Omar Feix do Nascimento ◽  
Antonio Balbin Villaverde ◽  
Renato Amaro Zângaro ◽  
Marcos Tadeu Tavares Pacheco ◽  
Steven F. Durrant

2021 ◽  
Vol 8 (4) ◽  
pp. 307-317
Author(s):  
Suleyman Yilmaz ◽  

<abstract> <p>In diagnosing the urinary tract and related diseases, the problem of light scattering from human urine was examined on the basis of classical electromagnetic theory. Numerical calculations were made for the designed cylindrical model with the help of optical parameters in the literature obtained from the laboratory test results of urine samples. In the designed model, the changes of the scattered intensity of the light from the urine solution according to the size parameter of the particles and the angular distribution of the system (including forward, side and back scattering) in the equatorial plane were obtained, in both transverse electric (TE) and transverse magnetic (TM) of the polarization states of the light. It was observed that the molecular density changes caused by the materials in the urine sample changed primarily the optical parameters and indirectly the intensity distribution of the scattered light. Thus, with the contribution of standard data provided as a result of light scatter calculations from urine samples taken from people with normal and different diseases, it will be easier to diagnose diseases that will be encountered later.</p> </abstract>


2018 ◽  
Vol 18 (19) ◽  
pp. 14555-14567 ◽  
Author(s):  
Carlos Toledano ◽  
Ramiro González ◽  
David Fuertes ◽  
Emilio Cuevas ◽  
Thomas F. Eck ◽  
...  

Abstract. The aim of this paper is to analyze the suitability of the high-mountain stations Mauna Loa and Izaña for Langley plot calibration of Sun photometers. Thus the aerosol optical depth (AOD) characteristics and seasonality, as well as the cloudiness, have been investigated in order to provide a robust estimation of the calibration uncertainty as well as the number of days that are suitable for Langley calibrations. The data used for the investigations belong to the AERONET and GAW-PFR networks, which maintain reference Sun photometers at these stations with long measurement records: 22 years at Mauna Loa and 15 years at Izaña. In terms of clear-sky and stable aerosol conditions, Mauna Loa (3397 m a.s.l.) exhibits on average 377 Langley plots (243 morning and 134 afternoon) per year suitable for Langley plot calibration, whereas Izaña (2373 m a.s.l.) shows 343 Langley plots (187 morning and 155 afternoon) per year. The background AOD (500 nm) values, on days that are favorable for Langley calibrations, are in the range 0.01–0.02 throughout the year, with well-defined seasonality that exhibits a spring maximum at both stations plus a slight summer increase at Izaña. The statistical analysis of the long-term determination of extraterrestrial signals yields to a calibration uncertainty of ∼ 0.25–0.5 %, this uncertainty being smaller in the visible and near-infrared wavelengths and larger in the ultraviolet wavelengths. This is due to atmospheric variability produced by changes in several factors, mainly the AOD. The uncertainty cannot be reduced based only on quality criteria of individual Langley plots and averaging over several days is shown to reduce the uncertainty to the needed levels for reference Sun photometers.


1997 ◽  
Vol 5 (2) ◽  
pp. 83-89 ◽  
Author(s):  
V.A. McGlone ◽  
H. Abe ◽  
S. Kawano

Kiwifruit firmness was estimated by scattering 864 nm laser light through the fruit to exiting angles at 20 to 55° around the circumference of the fruit from the incident beam. The intensity of scattered light emitted from the fruit increased with decreasing firmness, especially at larger angles. The intensity changes were modelled using an inverse power law relationship between the intensity and a distance factor D = sin(θ / 2), where θ is the exiting angle. With increasing firmness the proportionality constant S increases and the power coefficient of D, – n, decreases. The logarithm of S gave the best linear regression results against stiffness and rupture force; two standard measures of fruit firmness, with R2 values of 83% and 79%, respectively.


2016 ◽  
Vol 24 (6) ◽  
pp. 571-585 ◽  
Author(s):  
Ataollah Haddadi ◽  
Guillaume Hans ◽  
Brigitte Leblon ◽  
Zarin Pirouz ◽  
Satoru Tsuchikawa ◽  
...  

We used the Kubelka-Munk theory equations for calculating the absorption coefficient (Kλ), the scattering coefficient ( Sλ), the transport absorption (σλa), the reduced scattering coefficient [σλs(1 – g)] and the penetration depth (δλ) from visible-near infrared reflectance spectra acquired over thin samples of quaking aspen and black spruce conditioned at three different moisture levels. The computed absorption and scattering coefficients varied from 0.1 mm−1 to 4.0 mm−1 and from 5.5 mm−1 to 10.0 mm−1, respectively. The absorption coefficients varied according to the absorption band, but the scattering coefficients decreased slowly towards high wavelengths. The sample moisture content was then estimated using the partial least squares (PLS) regression method from the Kλ and/or Sλ spectra, and the resulting PLS models were compared to those obtained with raw and transformed [multiplicative scatter corrected (MSC), first and second derivative] absorption spectra. The best PLS models for black spruce, quaking aspen and both species were obtained when only the 800–1800 nm range was used with the raw or MSC spectra. They led to a root mean square error of cross validation ( RMSECV) of 1.40%, 1.09% and 1.23%, respectively, and to a coefficient of determination ( R2CV) higher than 0.94. We also found that the Kλ spectra between 800 nm and 1800 nm can provide PLS models having an acceptable accuracy for moisture content estimation ( R2CV = 0.83 and RMSECV = 2.32%), regardless of the species.


2018 ◽  
Vol 617 ◽  
pp. L7
Author(s):  
A. D. Schneider ◽  
C. P. Dullemond ◽  
B. Bitsch

Context. Vertically hydrostatic protoplanetary disk models are based on the assumption that the main heating source, stellar irradiation, does not vary much with time. However, it is known that accreting young stars are variable sources of radiation. This is particularly evident for outbursting sources such as EX Lupi and FU Orionis stars. Aims. We investigate how such outbursts affect the vertical structure of the outer regions of the protoplanetary disk, in particular their appearance in scattered light at optical and near-infrared wavelengths. Methods. We employ the 3D FARGOCA radiation-hydrodynamics code, in polar coordinates, to compute the time-dependent behavior of the axisymmetric disk structure. The temperature is computed self-consistently and time-dependently from the irradiation flux using a two-stage radiative transfer method: first the direct illumination is computed; then the diffuse radiation is treated with the flux-limited diffusion method. The outbursting inner disk region is not included explicitly. Instead, its luminosity is added to the stellar luminosity and is thus included in the irradiation of the outer disk regions. For time snapshots of interest we insert the density structure into the RADMC-3D radiative transfer code and compute the appearance of the disk at optical/near-infrared wavelengths, where we observe stellar light that is scattered off the surface of the disk. Results. We find that, depending on the amplitude of the outbursts, the vertical structure of the disk can become highly dynamic, featuring circular surface waves of considerable amplitude. These “hills” and “valleys” on the disk’s surface show up in the scattered light images as bright and dark concentric rings. Initially these rings are small and act as standing waves, but they subsequently lead to outward propagating waves, like the waves produced by a stone thrown into a pond. These waves continue long after the actual outburst has died out. Conclusions. Single, periodic, or quasiperiodic outbursts of the innermost regions of protoplanetary disks will necessarily lead to wavy structures on the surface of these disks at all radii. We propose that some of the multi-ringed structures seen in optical/infrared images of several protoplanetary disks may have their origin in outbursts that occurred decades or centuries ago. However, the multiple rings seen at (sub-)millimeter wavelengths in HL Tau and several other disks are not expected to be related to such waves.


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