Symmetrical Ball Check-Valve Based Rotation-Sensitive Pump

2013 ◽  
Vol 135 (11) ◽  
Author(s):  
Fábio A. Rahal ◽  
Cyro Ketzer Saul

In this work an electromagnetically actuated membrane pump, which allows flow reversion with a simple rotation of its valve system, is presented as a proof of concept. The valve system combines two symmetrical ball check-valves (SBCV), fabricated using laser machining techniques on PMMA (poly-methyl methacrylate) and PDMS (polydimethylsiloxane). The best efficiencies were achieved using glass balls within the SBCVs. This configuration provides flow rates from 0.2 to 6.0 ml/min with pressures up to 7 kPa. We also present a model which allows simulating the pumping behavior qualitatively, including the reversion after the rotation. The main advantages of the presented pump are wide range flow rates, low driving voltage (below 30 V), same pressure and flow rate in both direct and reverse pumping modes, and easily scalable to both bigger and smaller dimensions.

Author(s):  
Omer San ◽  
Sinan Eren Yalcin ◽  
Oktay Baysal

A micropump is an essential component of a microfluidic lab-on-a-chip device, especially for their biomedical applications. Based on their actuation method to drive the fluid flow, pumps may be categorized as mechanical or non-mechanical devices. In our proposed paper, we will report our comparative study of the most promising micropumps in each of these categories: a piezoelectrically-actuated micropump (PAμP) and an electroosmotic micropump (EOμP). A PAμP requires relatively high applied voltage, but provides high flow rates and has emerged to be the dominant type of micropump in biomedical applications. A valveless diffuser-nozzle micropump, driven by an oscillating membrane, has an important advantage, since the fabrication of any additional moving part, such as a check valve, would add significantly to its cost and render a more failure-prone device. The piezoelectrically actuated, valveless micropumps use moving mechanical parts to pump fluid and control the flow with optimized actuation frequency and applied voltage. In the present study, the microflow-structure interaction in the PAμP is modeled using an arbitrary Lagrangian-Eulerian method including a parametric study of applied voltage and frequency. An EOμP consists of multiple micron-scale channels in parallel that are subjected to the electroosmotic effect. However, a major drawback in the conventional design of an EOμP is the need for a high driving voltage to increase the flow rate or to overcome the back pressure. In the present study, a low-voltage EOμP is proposed and computationally modeled. Our simulations are performed in order to study the low-voltage EOμP for its various flow rate and back pressure characteristics. In the proposed paper, we will discuss our comparisons of PAμP and EOμP, with respect to their actuation mechanisms, applied voltages, pump sizes, flow rates and back pressures.


2015 ◽  
Vol 2 (1) ◽  
pp. 6-12
Author(s):  
Agus Sugiarta ◽  
Houtman P. Siregar ◽  
Dedy Loebis

Automation of process control in chemical plant is an inspiring application field of mechatronicengineering. In order to understand the complexity of the automation and its application requireknowledges of chemical engineering, mechatronic and other numerous interconnected studies.The background of this paper is an inherent problem of overheating due to lack of level controlsystem. The objective of this research is to control the dynamic process of desired level more tightlywhich is able to stabilize raw material supply into the chemical plant system.The chemical plant is operated within a wide range of feed compositions and flow rates whichmake the process control become difficult. This research uses modelling for efficiency reason andanalyzes the model by PID control algorithm along with its simulations by using Matlab.


1984 ◽  
Vol 19 (1) ◽  
pp. 87-100
Author(s):  
D. Prasad ◽  
J.G. Henry ◽  
P. Elefsiniotis

Abstract Laboratory studies were conducted to demonstrate the effectiveness of diffused aeration for the removal of ammonia from the effluent of an anaerobic filter treating leachate. The effects of pH, temperature and air flow on the process were studied. The coefficient of desorption of ammonia, KD for the anaerobic filter effluent (TKN 75 mg/L with NH3-N 88%) was determined at pH values of 9, 10 and 11, temperatures of 10, 15, 20, 30 and 35°C, and air flow rates of 50, 120, and 190 cm3/sec/L. Results indicated that nitrogen removal from the effluent of anaerobic filters by ammonia desorption was feasible. Removals exceeding 90% were obtained with 8 hours aeration at pH of 10, a temperature of 20°C, and an air flow rate of 190 cm3/sec/L. Ammonia desorption coefficients, KD, determined at other temperatures and air flow rates can be used to predict ammonia removals under a wide range of operating conditions.


Author(s):  
Michael D. T. McDonnell ◽  
Daniel Arnaldo ◽  
Etienne Pelletier ◽  
James A. Grant-Jacob ◽  
Matthew Praeger ◽  
...  

AbstractInteractions between light and matter during short-pulse laser materials processing are highly nonlinear, and hence acutely sensitive to laser parameters such as the pulse energy, repetition rate, and number of pulses used. Due to this complexity, simulation approaches based on calculation of the underlying physical principles can often only provide a qualitative understanding of the inter-relationships between these parameters. An alternative approach such as parameter optimisation, often requires a systematic and hence time-consuming experimental exploration over the available parameter space. Here, we apply neural networks for parameter optimisation and for predictive visualisation of expected outcomes in laser surface texturing with blind vias for tribology control applications. Critically, this method greatly reduces the amount of experimental laser machining data that is needed and associated development time, without negatively impacting accuracy or performance. The techniques presented here could be applied in a wide range of fields and have the potential to significantly reduce the time, and the costs associated with laser process optimisation.


1998 ◽  
Vol 37 (2) ◽  
pp. 293-300 ◽  
Author(s):  
Vickie L. Burris ◽  
John C. Little

A hypolimnetic aerator operating in one of the City of Norfolk's water supply reservoirs was tested. Dissolved oxygen (DO) profiles, water flow rate, and gas-phase holdup were measured over a wide range of applied air flow rates. A model that was developed to predict oxygen transfer in a Speece Cone was modified to conform to the conditions of the hypolimnetic aerator. By varying a single parameter (the initial bubble size) the model was found to provide a close fit to the experimental DO profiles as well as the observed gas-phase holdup. The model was used to show that a doubling in oxygen transfer may be achieved if initial bubble size is reduced from 5 mm to 2.5 mm. Knowing the initial bubble size, it should be possible to predict water velocity by incorporating the effect of momentum. Further work is now underway to test this approach and to examine the possibility of extending this generalized model to cover the range of hypolimnetic aeration and oxygenation devices.


Author(s):  
B. R. Nichols ◽  
R. L. Fittro ◽  
C. P. Goyne

Many high-speed, rotating machines across a wide range of industrial applications depend on fluid film bearings to provide both static support of the rotor and to introduce stabilizing damping forces into the system through a developed hydrodynamic film wedge. Reduced oil supply flow rate to the bearings can cause cavitation, or a lack of a fully developed film layer, at the leading edge of the bearing pads. Reducing oil flow has the well-documented effects of higher bearing operating temperatures and decreased power losses due to shear forces. While machine efficiency may be improved with reduced lubricant flow, little experimental data on its effects on system stability and performance can be found in the literature. This study looks at overall system performance of a test rig operating under reduced oil supply flow rates by observing steady-state bearing performance indicators and baseline vibrational response of the shaft. The test rig used in this study was designed to be dynamically similar to a high-speed industrial compressor. It consists of a 1.55 m long, flexible rotor supported by two tilting pad bearings with a nominal diameter of 70 mm and a span of 1.2 m. The first bending mode is located at approximately 5,000 rpm. The tiling-pad bearings consist of five pads in a vintage, flooded bearing housing with a length to diameter ratio of 0.75, preload of 0.3, and a load-between-pad configuration. Tests were conducted over a number of operating speeds, ranging from 8,000 to 12,000 rpm, and bearing loads, while systematically reducing the oil supply flow rates provided to the bearings under each condition. For nearly all operating conditions, a low amplitude, broadband subsynchronous vibration pattern was observed in the frequency domain from approximately 0–75 Hz. When the test rig was operated at running speeds above its first bending mode, a distinctive subsynchronous peak emerged from the broadband pattern at approximately half of the running speed and at the first bending mode of the shaft. This vibration signature is often considered a classic sign of rotordynamic instability attributed to oil whip and shaft whirl phenomena. For low and moderate load conditions, the amplitude of this 0.5x subsynchronous peak increased with decreasing oil supply flow rate at all operating speeds. Under the high load condition, the subsynchronous peak was largely attenuated. A discussion on the possible sources of this subsynchronous vibration including self-excited instability and pad flutter forced vibration is provided with supporting evidence from thermoelastohydrodynamic (TEHD) bearing modeling results. Implications of reduced oil supply flow rate on system stability and operational limits are also discussed.


2018 ◽  
Vol 03 (01) ◽  
pp. 1850002 ◽  
Author(s):  
Janis Edelmann ◽  
Andrew J. Petruska ◽  
Bradley J. Nelson

Magnetically controlled catheters and endoscopes can improve minimally invasive procedures as a result of their increased maneuverability when combined with modern magnetic steering systems. However, such systems have two distinct shortcomings: they require continuous information about the location of the instrument inside the human body and they rely on models that accurately capture the device behavior, which are difficult to obtain in realistic settings. To address both of these issues, we propose a control algorithm that continuously estimates a magnetic endoscope’s response to changes in the actuating magnetic field. Experiments in a structured visual environment show that the control method is able to follow image-based trajectories under different initial conditions with an average control error that measures 1.8 % of the trajectory length. The usefulness for medical procedures is demonstrated with a bronchoscopic inspection task. In a proof-of-concept study, a custom 2[Formula: see text]mm diameter miniature camera endoscope is navigated through an anatomically correct lung phantom in a clinician-controlled manner. This represents the first demonstration of the controlled manipulation of a magnetic device without localization, which is critical for a wide range of medical procedures.


Pharmaceutics ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 73
Author(s):  
Huimin Yan ◽  
Ying Hu ◽  
Antonina Akk ◽  
Muhammad Farooq Rai ◽  
Hua Pan ◽  
...  

Osteoarthritis (OA) is a progressive joint disease that causes significant disability and pain and for which there are limited treatment options. We posit that delivery of anabolic factors that protect and maintain cartilage homeostasis will halt or retard OA progression. We employ a peptide-based nanoplatform to deliver Wingless and the name Int-1 (WNT) 16 messenger RNA (mRNA) to human cartilage explants. The peptide forms a self-assembled nanocomplex of approximately 65 nm in size when incubated with WNT16 mRNA. The complex is further stabilized with hyaluronic acid (HA) for enhanced cellular uptake. Delivery of peptide-WNT16 mRNA nanocomplex to human cartilage explants antagonizes canonical β-catenin/WNT3a signaling, leading to increased lubricin production and decreased chondrocyte apoptosis. This is a proof-of-concept study showing that mRNA can be efficiently delivered to articular cartilage, an avascular tissue that is poorly accessible even when drugs are intra-articularly (IA) administered. The ability to accommodate a wide range of oligonucleotides suggests that this platform may find use in a broad range of clinical applications.


PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6929 ◽  
Author(s):  
Alexandra Vassilieva ◽  
Markus Harboe Olsen ◽  
Costanza Peinkhofer ◽  
Gitte Moos Knudsen ◽  
Daniel Kondziella

Background Levels of consciousness in patients with acute and chronic brain injury are notoriously underestimated. Paradigms based on electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) may detect covert consciousness in clinically unresponsive patients but are subject to logistical challenges and the need for advanced statistical analysis. Methods To assess the feasibility of automated pupillometry for the detection of command following, we enrolled 20 healthy volunteers and 48 patients with a wide range of neurological disorders, including seven patients in the intensive care unit (ICU), who were asked to engage in mental arithmetic. Results Fourteen of 20 (70%) healthy volunteers and 17 of 43 (39.5%) neurological patients, including 1 in the ICU, fulfilled prespecified criteria for command following by showing pupillary dilations during ≥4 of five arithmetic tasks. None of the five sedated and unconscious ICU patients passed this threshold. Conclusions Automated pupillometry combined with mental arithmetic appears to be a promising paradigm for the detection of covert consciousness in people with brain injury. We plan to build on this study by focusing on non-communicating ICU patients in whom the level of consciousness is unknown. If some of these patients show reproducible pupillary dilation during mental arithmetic, this would suggest that the present paradigm can reveal covert consciousness in unresponsive patients in whom standard investigations have failed to detect signs of consciousness.


2014 ◽  
Vol 36 (3) ◽  
pp. 405-412 ◽  
Author(s):  
Robert Goovaerts ◽  
Tom Van Assche ◽  
Marc Sonck ◽  
Joeri Denayer ◽  
Gert Desmet

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